• Tissue Engineering and Regenerative Medicine
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• v.15 no.6
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• pp.751-760
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• 2018

BACKGROUND: Bone tissue engineering based on pluripotent stem cells (PSCs) is a new approach to deal with bone defects. Protocols have been developed to generate osteoblasts from PSCs. However, the low efficiency of this process is still an important issue that needs to be resolved. Many studies have aimed to improve efficiency, but developing accurate methods to determine efficacy is also critical. Studies using pluripotency to estimate efficacy are rare. Telomerase is highly associated with pluripotency. METHODS: We have described a quantitative method to measure telomerase activity, telomeric repeat elongation assay based on quartz crystal microbalance (QCM). To investigate whether this method could be used to determine the efficiency of in vitro osteogenic differentiation based on pluripotency, we measured the pluripotency pattern of cultures through stemness gene expression, proliferation ability and telomerase activity, measured by QCM. RESULTS: We showed that the pluripotency pattern determined by QCM was similar to the patterns of proliferation ability and gene expression, which showed a slight upregulation at the late stages, within the context of the general downregulation tendency during differentiation. Additionally, a comprehensive gene expression pattern covering nearly every stage of differentiation was identified. CONCLUSION: Therefore, this assay may be powerful tools for determining the efficiency of differentiation systems based on pluripotency. In this study, we not only introduce a new method for determining efficiency based on pluripotency, but also provide more information about the characteristics of osteogenic differentiation which help facilitate future development of more efficient protocols.

• Women's Health Nursing
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• v.13 no.4
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• pp.237-244
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• 2007

• Molecular & Cellular Toxicology
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• v.3 no.sup4
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• pp.37.5-37.5
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• 2007

• Korean Journal of Social Welfare
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• v.35
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• pp.107-131
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• 1998

This study tried to formulate and operate an interdisciplinary case management team in Eun-Pyung Gu, Seoul. This was a part of an effort to promote efficiency of service delivery system for low-income elderly or the handicapped by linking. coordinating. and integrating various health and human services providers. In-depth qualitative analysis described the process of which the interdisciplinary case management team was formed, along with the process of the team operation. The interdisciplinary team consisted of home helpers, visiting nurses, and social workers from Health Center and Social Welfare Centers. Issues dealt with by the team include: 1) information exchange of clients' social, economic, and medical situations; 2) identification of types of service provision to clients; 3) clients' needs assessment and its prioritization; 4) assignment of a leading case manager for each case; 5) identification of problems and issues regarding integration of service delivery system The team approach to case management contributed to the systematic delivery of services to the elderly and the handicapped by avoiding service duplication and fragmentation. This study argued that public agency played a key role in constituting and operating the interdisciplinary case management team Suggestions for further studies were presented.

• Journal of the Korean Home Economics Association
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• v.27 no.3
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• pp.13-28
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• 1989

With the purpose of identifying clothing for persons with special needs one of new directions in Clothing and Textiles, this pater comparatively analyzed current curriculum and research trends related to this field between Korea and America. Questionaire was distributed to 25 Korean colleges with Clothing and Textiles department and 4 American colleges known for special clothing study. Questions regarded the name of course, level (grade), number of credit houre, prerequisits and supporting courses, subjects of lecture and projects, way of managing lecture and projects, evaluation system, other special characteristics. Resources for analyzing research trends are Thesis and Dissertations in Clothing and Textiles, Research Journal of Clothing & Textiles/Home Economics Association, College Professors' research reports collection, of both Korea and America. Years of publications are 1972∼1986 (America), 1978∼1988 (Korea). Findings are as follows; 1. Clothing for special needs can be classified into various groups; Clothing for physically handicapped, mentally retarded, elderly, unusual-sized, pregnant/nursing mothers, institutionalized, protective clothing, uniform/career apparel. 2. Management of coursework related to special clothing has several common characteristics specially in America; Building-up coursework, problem-solving orientation, cooperative team-preject, interdisciplinary approach, client-versus-designer preference, community involvement. In Korea, a few school only has special clothing coursework and its scope of study was very limited. 3. Majority of research reports done with the subjects of special clothing had made for physically handicapped people and the elderly. Protective clothing and uniform have recently been paid much interests. 4. Researchers had mainly concerned on Design and Construction Aspects and nextly on social-psychological aspects. However, in America, selection and care aspects and marketing aspects of special clothing have been very procuctive issues recently. 5. Study on clothing for special needs has several opportunities to be stressed and improvements to be strengthened. Opportunities included active participation to the welfare of community society, strong publicity of accurate professional image, share with business and industry, interdisciplinary approach and new job market. Improvements were discussed in terms of strengthening supporting courses/prerequistes, intensifying interdisciplinary cooperation, provoking strong community involvement and securing financial support and research funds.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.23 no.12
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• pp.1571-1577
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• 2019

There is a growing interest in psychological counseling and pyschotherapy and many experts are working to help clients more efficiently. Given the many advantages of cyber counseling can be a good alternative to traditional face-to-face counseling. This paper examines the trends of cyber counseling and psychotherapy in South Korea. As a result, when comparing traditional counseling with cyber counseling, cyber counseling had advantages such as high accessibility, convenience, cost reduction effect, and inconvenience in face-to-face counseling. In addition, cyber counseling in South Korea began in the late 1980s, and many studies were conducted for teenagers who are familiar with ICT. Lastly, I briefly researched the current status of cyber counseling and psychotherapy in South Korea. Currently, more active cyber counseling and psychotherapeutic interventions are being carried out using images, AI, and VR. However, because the interdisciplinary approach is somewhat lacking, it is necessary to develop various counseling and psychotherapy programs and verify the effectiveness through the interdisciplinary approach.

• The Journal of Korean Philosophical History
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• no.27
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• pp.387-415
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• 2009

The crisis of moral-ethical school subject is related to the scientific identity of moral education in Korean society. Because it's identity hasn't been established yet exactly. At past time 'National Ethics' included not only moral education, but also anti-Communist education and education of political ideology or propaganda. The scientific foundation of ethical education is on ethics, and it is a branch of philosophy. But to escape this fact, some scholars relating with ethical education claimed to need 'interdisciplinary approach' to ethical subject. As a result, they allowed other department to give their certificates. Futhermore it is at a crisis to be integrated into social subject. Philosophy as scientific origin of ethics has already not interdisciplinary character but the idea of integrated science. So there is no necessity for finding another scientific foundation. Now following the original goal of ethical education, they try to train the ability of moral judgement to solve various moral problems rationally, and to cultivate moral disposition that can practice the ideal and principles of life.

• The Journal of Korean Academy of Prosthodontics
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• v.51 no.4
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• pp.339-346
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• 2013

In case of missing of permanent teeth by trauma or innate defect, the decision of treatment modalities and application timing have an important effect on the prognosis of oral rehabilitation. In this case report, interdisciplinary approach between the orthodontic and prosthodontic treatment, the way to re-establish the collapsed occlusal vertical dimension, and implant prosthetic considerations will be discussed. Proper diagnosis on teeth and craniofacial skeleton was made prior to treatment and provisional restorations were used in regard of growth patterns of the patient. Finally, the edentulous areas were restored with fixed implant prostheses. Diagnosis, treatment rationale and prognosis will be discussed thoroughly.

• Knowledge Management Research
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• v.21 no.1
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• pp.99-116
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• 2020

Text is the most widely used means of exchanging or expressing knowledge and information in the real world. Recently, researches on structuring unstructured text data for text analysis have been actively performed. One of the most representative document embedding method (i.e. doc2Vec) generates a single vector for each document using the whole corpus included in the document. This causes a limitation that the document vector is affected by not only core words but also other miscellaneous words. Additionally, the traditional document embedding algorithms map each document into only one vector. Therefore, it is not easy to represent a complex document with interdisciplinary subjects into a single vector properly by the traditional approach. In this paper, we introduce a multi-vector document embedding method to overcome these limitations of the traditional document embedding methods. After introducing the previous study on multi-vector document embedding, we visually analyze the effects of the multi-vector document embedding method. Firstly, the new method vectorizes the document using only predefined keywords instead of the entire words. Secondly, the new method decomposes various subjects included in the document and generates multiple vectors for each document. The experiments for about three thousands of academic papers revealed that the single vector-based traditional approach cannot properly map complex documents because of interference among subjects in each vector. With the multi-vector based method, we ascertained that the information and knowledge in complex documents can be represented more accurately by eliminating the interference among subjects.

• Journal of Biomedical Engineering Research
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• v.37 no.5
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• pp.161-167
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• 2016

Recent technological advances in sensor fabrication and bio-signal processing enabled non-constraint and non-intrusive measurement of human bio-signals. Especially, non-constraint measurement of ECG makes it available to estimate various human health parameters such as heart rate. Additionally, non-constraint ECG measurement of wheelchair user provides real-time health parameter information for emergency response. For accurate emergency response with low false alarm rate, it is necessary to discriminate quality levels of ECG measured using non-constraint approach. Health parameters acquired from low quality ECG results in inaccurate information. Thus, in this study, a machine learning based approach for three-class classification of ECG quality level is suggested. Three sensors are embedded in the back seat, chest belt, and handle of automatic wheelchair. For the two sensors embedded in back seat and chest belt, capacitively coupled electrodes were used. The accuracy of quality level classification was estimated using Monte Carlo cross validation. The proposed approach demonstrated accuracy of 94.01%, 95.57%, and 96.94% for each channel of three sensors. Furthermore, the implemented algorithm enables classification of user posture by detection of contacted electrodes. The accuracy for posture estimation was 94.57%. The proposed algorithm will contribute to non-constraint and robust estimation of health parameter of wheelchair users.