• Journal of Photoscience
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• v.11 no.32
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• pp.65-69
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• 2004

The mechanism of interaction of four coumarin derivatives (CDS) with bovine serum albumin (BSA) was studied using spectrofluorometric technique. It was found that the coumarin ring common to all CDS makes major contribution to interaction. Binding affinities could be related to parachor values of CDS. Stem-Volmer plots indicated the presence of static component in the quenching mechanism. Results also showed that both tryptophan residues of protein are accessible to CDS. The high magnitude of rate constant of quenching indicated that the process of energy transfer occurs by intermolecular interaction forces and thus CDS binding site is in close proximity to tryptophan residues of BSA. Binding studies in the presence of the hydrophobic probe, 8-anilino-l-naphthalein-sulfonic acid showed that there is hydrophobic interaction between CDS and the probe and they do not share common sites in BSA. Thermodynamic parameters obtained from data at different temperatures showed that the binding of CDS to BSA involve hydrophobic bonds predominantly. The effects of various metal ions on the binding of CDS with BSA were also investigated.

• Steel and Composite Structures
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• v.13 no.2
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• pp.109-122
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• 2012

An efficient and accurate algorithm is proposed to evaluate the reliability of cable-stayed bridges accounting for soil-pile interaction. The proposed algorithm integrates the finite-element method and the response surface method. The finite-element method is used to model the cable-stayed bridge including soil-pile interaction. The reliability index is evaluated based on the response surface method. Uncertainties in the superstructure, the substructure and load parameters are incorporated in the proposed algorithm. A long span steel cable-stayed bridge with a main span length of 1088 m built in China is considered as an illustrative example. The reliability of the bridge is evaluated for the strength and serviceability performance functions. Results of the study show that when strength limit states for both girder and tower are considered, soil-pile interaction has significant effects on the reliability of steel cable-stayed bridges. Further, a detailed sensitivity study shows that the modulus of subgrade reaction is the most important soil-pile interaction-related parameter influencing the reliability of steel cable-stayed bridges.

• Structural Engineering and Mechanics
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• v.83 no.2
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• pp.207-227
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• 2022

In general, the interaction conditions between the discrete stones are not taken into account by structural engineers during the modeling and analyzing of historical stone bridges. However, many structural damages in the stone bridges occur due to ignoring the interaction conditions between discrete stones. In this study, it is aimed to examine the seismic behavior of a historical stone bridge by considering the interaction stiffness parameters between stone elements. For this purpose, Tokatli historical stone arch bridge was built in 1179 in Karabük-Turkey, is chosen for three-dimensional (3D) seismic analyses. Firstly, the 3D finite-difference model of the Tokatli stone bridge is created using the FLAC3D software. During the modeling processes, the Burger-Creep material model which was not used to examine the seismic behavior of historical stone bridges in the past is utilized. Furthermore, the free-field and quiet non-reflecting boundary conditions are defined to the lateral and bottom boundaries of the bridge. Thanks to these boundary conditions, earthquake waves do not reflect in the 3D model. After each stone element is modeled separately, stiffness elements are defined between the stone elements. Three situations of the stiffness elements are considered in the seismic analyses; a) for only normal direction b) for only shear direction c) for both normal and shear directions. The earthquake analyses of the bridge are performed for these three different situations of the bridge. The far-fault and near-fault conditions of 1989 Loma Prieta earthquake are taken into account during the earthquake analyses. According to the seismic analysis results, the directions of the stiffness parameters seriously changed the earthquake behavior of the Tokatli bridge. Moreover, the most critical stiffness parameter is determined for seismic analyses of historical stone arch bridges.

• Coupled systems mechanics
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• v.13 no.4
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• pp.293-310
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• 2024

This paper investigates the dynamic response of structures during earthquakes and provides a clear understanding of soil-structure interaction phenomena. It analyses various parameters, comprising ground shear wave velocity and structure properties. The effect of soil impedance function form on the structural response of the system through the use of springs and dashpots with two frequency cases: independent and dependent frequencies. The superstructure and the ground were modeled linearly. Using the substructure method, two different approaches are used in this study. The first is an analytical formulation based on the dynamic equilibrium of the soil-structure system modeled by an analog model with three degrees of freedom. The second is a numerical analysis generated with 2D finite element modeling using ABAQUS software. The superstructure is represented as a SDOF system in all the SSI models assessed. This analysis establishes the key parameters affecting the soil-structure interaction and their effects. The different results obtained from the analysis are compared for each studied case (frequency-independent and frequency-dependent impedance functions). The achieved results confirm the sensitivity of buildings to soil-structure interaction and highlight the various factors and effects, such as soil and structure properties, specifically the shear wave velocity, the height and mass of the structure. Excitation frequency, and the foundation anchoring height, also has a significant impact on the fundamental parameters and the response of the coupled system at the same time. On the other hand, it have been demonstrated that the impedance function forms play a critical role in the accurate evaluation of structural behavior during seismic excitation. As a result, the evaluation of SSI effects on structural response must take into account the dynamic properties of the structure and soil accordingly.

• Journal of Korea Foundry Society
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• v.10 no.2
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• pp.116-118
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• 1990

• Journal of the Korea Computer Graphics Society
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• v.2 no.2
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• pp.21-28
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• 1996

The nature of complexity of medical images makes them difficult to segment using standard techniques. Therefore the usual approaches to segment images continue to predominantly involve manual interaction. But it tediously consumes a good deal of time and efforts of the experts. Hereby a nonmanual parameters estimation which can replace the manual interaction is needed to solve the problem of redundant manual works for an image segmentation. This paper attempts to estimate parameters for an image region segmentation using Scale Space Filtering. This attempt results in estimating the number of regions, their boundary and each representatives to be segmented 2-dimensionally and 3-dimensionally. Using this algorithm, we may diminish the problem of wasted time and efforts for finding prerequisite segmentation parameters, and lead the relatively reasonable result of region segmentation.

• Ocean Systems Engineering
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• v.6 no.1
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• pp.99-115
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• 2016

In meeting the technical needs for deepwater conditions and overcoming the shortfalls of single-layer pipes for deepwater applications, pipe-in-pipe (PIP) systems have been developed. While, for PIP pipelines directly laid on the seabed or with partial embedment, one of the primary service risks is lateral buckling. The critical axial force is a key factor governing the global lateral buckling response that has been paid much more attention. It is influenced by global imperfections, submerged weight, stiffness, pipe-soil interaction characteristics, et al. In this study, Finite Element Models for imperfect PIP systems are established on the basis of 3D beam element and tube-to-tube element in Abaqus. A parameter study was conducted to investigate the effects of these parameters on the critical axial force and post-buckling forms. These parameters include structural parameters such as imperfections, clearance, and bulkhead spacing, pipe/soil interaction parameter, for instance, axial and lateral friction properties between pipeline and seabed, and load parameter submerged weight. Python as a programming language is been used to realize parametric modeling in Abaqus. Some conclusions are obtained which can provide a guide for the design of PIP pipelines.

• Proceedings of the Korea Water Resources Association Conference
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• 2023.05a
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• pp.287-287
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• 2023

Surface water-groundwater interaction (SWGI) is an important hydrological process that influences both the quantity and quality of water resources. However, regional scale SWGI model calibration and uncertainty analysis have been a challenge because integrated models inherently carry a vast number of parameters, modeling assumptions, and inputs, potentially leaving little time and budget to explore questions related to model performance and forecasting. In this study, we have proposed the application of iterative ensemble smoother (IES) for uncertainty analysis and calibration of the widely used integrated surface-subsurface model, SWAT-MODFLOW. SWAT-MODFLOW integrates Soil and Water Assessment Tool (SWAT) and a three-dimensional finite difference model (MODFLOW). The model was calibrated using a parameter estimation tool (PEST). The major advantage of the employed IES is that the number of model runs required for the calibration of an ensemble is independent of the number of adjustable parameters. The pilot point approach was followed to calibrate the aquifer parameters, namely hydraulic conductivity, specific storage, and specific yield. The parameter estimation process for the SWAT model focused primarily on surface-related parameters. The uncertainties both in the streamflow and groundwater level were assessed. The work presented provides valuable insights for future endeavors in coupled surface-subsurface modeling, data collection, model development, and informed decision-making.

• Journal of the Korean Society of Safety
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• v.27 no.2
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• pp.57-64
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• 2012

For the vibration control of earthquake-excited buildings, an optimal design method of integrated control system considering soil-structure interaction is studied in this paper. Interaction between soils and the base of the building is simply modeled as lumped parameters and equations of motion are derived. The equations of motion are transformed into the state space equations and the probabilistic excitations such as Kanai-Tajumi power spectral density function is introduced. Then an optimization problem is formulated as finding hybrid or integrated control systems which minimizes the stochastic responses of the building structure for given constraints. In order to investigate the feasibility of the optimization method, an example design and numerical simulations are performed with tenstory building. Finally, numerical results are compared with a conventional design case that soil-structure interaction is not considered.

• Structural Engineering and Mechanics
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• v.1 no.1
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• pp.17-30
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• 1993

A practical multi-spring model is proposed for a nonlinear analysis of reinforced concrete members, especially columns, taking into account the interaction of axial load and bi-directional bending moment. The parameters of the model are determined on the basis of material properties and section geometry. The axial force-moment interaction curve of reinforced concrete sections predicted by the model was shown to agree well with those obtained by the flexural analysis utilizing realistic stress-strain relations of materials. The reliability of the model was also examined with respect to the test of reinforced concrete columns subjected to varying axial load and bi-directional lateral load reversals. The analytical results agreed well with the experiment.