• Journal of Pharmaceutical Investigation
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• v.26 no.3
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• pp.169-174
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• 1996

Inclusion complexes of diclofenac sodium with ${\beta}-cyclodextrin$ were prepared in aqueous solution, alkaline solution and solid phase. The interaction of diclofenac sodium with ${\beta}-cyclodextrin$ in pH 9.0 alkaline solution was evaluated by the solubility method and the instrumental analysis such as thermal analysis, infrared spectroscopy, X-ray diffractometry. The solubility of diclofenac sodium was increased linearly with the increase in the concentration of ${\beta}-cyclodextrin$up to 0.15 mol and showed that the aqueous solubility rate of diclofenac sodium was significantly increased by complex with ${\beta}-cyclodextrin$. The optimum composition of this complex was one molecule of ${\beta}-cyclodextrin$ included 1.59 molecular weight of diclofenac sodium as a guest molecule. The pharmacokinetic parameters of the diclofenac sodium and the complex with ${\beta}-cyclodextrin$ were studied in rats by oral route. $T_{max}$ between drug alone and inclusion complex showed significant difference to be 120 minute and 20 minute respectively. Both of $C_{max}$ and AUC of inclusion complex was about 40% higher than drug alone. It is estimated from the data in this study that complexation of diclofenac sodium with ${\beta}-cyclodextrin$ increased the absorption rate and improved the bioavalability of the diclofenac sodium by the formation of a water-soluble complexes.

• Journal of the Korean Society of Clothing and Textiles
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• v.39 no.2
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• pp.233-246
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• 2015

Focus on Digital Fashion Image, the conceptual framework for the thesis is established from Virtuality in Digital Art. Formative characteristics and aesthetic characteristics were studied by classifying the Digital Fashion Image applied and expressed by digital media and technology. A detective research method was used for a case study. A literature study for case-by-case data was analyzed with focus on the works expressing fashion that utilized digital media and technology since the 2000s. Through this study, the Digital revolution has created the socio-cultural impact of a Virtual representation to implement technology and fashion culture that finds ways to take advantage of the image shown in a Digital Fashion Media by understanding Virtuality. The results are as follows. First, it was a re-formation of the fashion culture through the experience of virtuality with mental zone parameters between the media 'Mediation Code'. Reflect the reality of the virtual environment as represented by a cultural image of fashion brands and fashion that reset the team relationship and formed a Homo Ludens cultural code. Second, 'Interactive Exchange' acts on the exchange interaction between the method of digital technology, the human and the machine as well as the technical interoperability of network elements and techniques. This exchange is applied to fashion images that express emotion. Forming personalized fashion items and the user interactively storage that expresses the interactive exchange to forward the identity of the emotional fashion by a change in the message delivery system fashion. Third, the emphasis on intuitive artistic expression 'Synesthesia Immersion' induces a sense of immersion and excitement through the fusion of the interconnected. Enhance a visual image in fashion sensory representation and maximize a tactile and visual virtual reality involvement.

• Applied Chemistry for Engineering
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• v.21 no.3
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• pp.337-342
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• 2010

The interaction of monochlorophenol isomers with the micellar system of TTAB (tetradecyltrimethylammonium bromide) was studied by the UV/Vis spectrophotometric method. The solubilization constants ($K_s$) of monochlorophenol isomers into this micellar system have been measured with the change of temperature. Various thermodynamic parameters (${\Delta}G^{\circ}_s$, ${\Delta}H^{\circ}_s$, and ${\Delta}S^{\circ}_s$) have been calculated and analyzed from the dependence of $K_s$ values on the temperature. The results show that the values of ${\Delta}G^{\circ}_s$ and ${\Delta}H^{\circ}_s$ are all negative but the values of ${\Delta}S^{\circ}_s$ are all positive for the solubilizations of all isomers within the measured temperature range. The effects of additives (n-butanol and NaCl) on the solubilization of monochlorophenol isomers by the same surfactant system have been also measured. There was a great change on the values of $K_s$ and CMC simultaneously with these additives. From these changes we can postulate the solubilization sites of each isomer in the micellar system of TTAB.

• Restorative Dentistry and Endodontics
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• v.41 no.1
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• pp.37-43
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• 2016

Objectives: The purpose of this study was to compare the marginal and internal fit of nano-composite CAD-CAM restorations. Materials and Methods: A full veneer crown and an mesio-occluso-distal (MOD) inlay cavity, which were prepared on extracted human molars, were used as templates of epoxy resin replicas. The prepared teeth were scanned and CAD-CAM restorations were milled using Lava Ultimate (LU) and experimental nano-composite CAD/CAM blocks (EB) under the same milling parameters. To assess the marginal and internal fit, the restorations were cemented to replicas and were embedded in an acrylic mold for sectioning at 0.5 mm intervals. The measured gap data were pooled according to the block types and measuring points for statistical analysis. Results: Both the block type and measuring point significantly affected gap values, and their interaction was significant (p = 0.000). In crowns and inlays made from the two blocks, gap values were significantly larger in the occlusal area than in the axial area, while gap values in the marginal area were smallest (p < 0.001). Among the blocks, the restorations milled from EB had a significantly larger gap at all measuring points than those milled from LU (p = 0.000). Conclusions: The marginal and internal gaps of the two nano-composite CAD/CAM blocks differed according to the measuring points. Among the internal area of the two nano-composite CAD/CAM restorations, occlusal gap data were significantly larger than axial gap data. The EB crowns and inlays had significantly larger gaps than LU restorations.

• Journal of the Korean Society of Hazard Mitigation
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• v.9 no.6
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• pp.1-9
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• 2009

An analysis program to predict the behavior of a concrete filled steel tube column (CFT) was developed. It considered confining effect, material nonlinearity, strain hardening of steel, and initial axial load. With the developed program, axial load-bending moment interaction analyses, moment-lateral displacement relation analyses, and lateral load-lateral displacement relation analyses were performed. For the verification of the developed program, analysis results were compared with the test results from the other researches. The verified results showed that the developed program predicted the behavior of the CFT column with agreeable accuracy. And they showed that it is necessary to consider the confining effect for the reasonable analysis of the CFT column. A simple parametric study was performed and it chose the strength of unconfined concrete and the thickness of a steel tube as the major parameters affecting the behavior of the CFT column. The parametric analysis results showed that the CFT column had higher strength and smaller ductility by increasing the strength of concrete. But the CFT column showed higher strength and larger ductility by increasing the thickness of the steel tube.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.32 no.9
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• pp.27-34
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• 2004

A computational study on the supersonic flow around the lateral jet controlled missile has been performed. For this purpose a three dimensional Navier-Stokes computer code(AADL3D) has been developed and case studies have been performed by comparing the normal force coefficient and the moment coefficient of a missile body for several parameters such as angles of attack, circumferential jet positions, and spouting jet angles. Missile surface is divided into four regions with respect to the center of gravity, and the normal force and moment distribution at each region are compared. The results show different behavior of the normal force and moment variation according to each parameter. Furthermore, it is shown that the pitching moment can be minimized through proper combination of each parameter.

• Korean Journal of Environmental Agriculture
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• v.28 no.2
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• pp.106-112
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• 2009

The increased $CO_2$ and temperature (700 ${\mu}$mol.$mol^{-1}$ $CO_2$ and $30^{\circ}C$) was compared with ambient growth conditions (400 ${\mu}$mol.$mol^{-1}$ $CO_2$ and $25^{\circ}C$) in hot pepper. Gas exchange measurements, including net photosynthesis ($P_{net}$) and stomatal conductance ($g_s$), were taken according to treatment in fields of peppers grown in Suwon and Asan during 2008. The increased treatment $P_{net}$ by 35-45% throughout the season and was statistically significant in t-tests (p < 0.001); however, it did not significantly affect $g_s$. In addition, the gas exchange parameters in sun and shade leaves were measured. The difference between the sun and shade leaves was much greater than that between the elevated and ambient treatments, especially at harvest. Four commercial cultivars of hot pepper, Chunhasangsa, Ryukang, Manitta, and Olympic, were also compared by ANOVA. Chunhasangsa had the highest $P_{net}$, which decreased by 30% from the vegetative to the harvest stage. Based on a factorial design, the effect of the increased $CO_2$ and temperature was assessed based on the temperature, $CO_2$, and their interaction effects. Orthogonal contrasts showed that the effects of temperature on $P_{net}$ and $g_s$ were significant, whereas $CO_2$ and their interactions were not.

• The Journal of Advanced Prosthodontics
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• v.6 no.6
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• pp.427-433
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• 2014

PURPOSE. Surface color is one of the main criteria to obtain an ideal esthetic. Many factors such as the type of the material, surface specifications, number of firings, firing temperature and thickness of the porcelain are all important to provide an unchanged surface color in dental ceramics. The aim of this study was to evaluate the color changes in dental ceramics according to the material type and glazing methods, during the multiple firings. MATERIALS AND METHODS. Three different types of dental ceramics (IPS Classical metal ceramic, Empress Esthetic and Empress 2 ceramics) were used in the study. Porcelains were evaluated under five main groups according to glaze and natural glaze methods. Color changes (${\Delta}E$) and changes in color parameters (${\Delta}L$, ${\Delta}a$, ${\Delta}b$) were determined using colorimeter during the control, the first, third, fifth, and seventh firings. The statistical analysis of the results was performed using ANOVA and Tukey test. RESULTS. The color changes which occurred upon material-method-firing interaction were statistically significant (P<.05). ${\Delta}E$, ${\Delta}L$, ${\Delta}a$ and ${\Delta}b$ values also demonstrated a negative trend. The MC-G group was less affected in terms of color changes compared to other groups. In all-ceramic specimens, the surface color was significantly affected by multiple firings. CONCLUSION. Firing detrimentally affected the structure of the porcelain surface and hence caused fading of the color and prominence of yellow and red characters. Compressible all-ceramics were remarkably affected by repeated firings due to their crystalline structure.

• Korean Chemical Engineering Research
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• v.53 no.2
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• pp.193-198
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• 2015

The high-pressure phase behavior of a polycaprolactone (Mw=56,145 g/mol, polydispersity 1.2), dichloromethane, and carbon dioxide ternary system was measured using a variable-volume view cell. The experimental temperatures and pressures ranged from 313.15 K to 353.15 K and up to 300 bar as functions of the $CO_2$/dichloromethane mass ratio and temperature, at poly(D-lactic acid) weight fractions of 1.0, 2.0, and 3.0%. The correlation results were obtained from the hybrid equation of state (Peng-Robinson equation of state + SAFT equation of state) for the $CO_2$-polymer system using the van der Waals one-fluid mixing rule. The three binary interaction parameters were optimized by the simplex method algorithm.

• Journal of Communications and Networks
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• v.9 no.4
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• pp.511-523
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• 2007

In broadband convergence network(BcN), heterogeneous broadband wired & wireless subnetworks and various terminal equipments will be interconnected. In order to provide end-to-end realtime multimedia services on such heterogeneous networking environment, as a result, two major problems should be resolved: i) Multimedia session establishment & negotiation that adjusts the differences in the capability of multimedia data processing at the end terminal nodes, ii) quality of service(QoS)-guaranteed connection establishment or resource reservation with connection admission control(CAC) in each heterogeneous subnetworks along the path. The session layer signaling(e.g., SIP/SDP) should be extended for QoS negotiation, and must be tightly cooperating with network layer signaling or resource reservation with CAC function. In this paper we propose a session and connection management architecture for the QoS-guaranteed realtime multimedia service provisioning on BcN, with Q-SIP/SDP, resource reservation protocol with traffic engineering extension, and CAC functions. The detailed interaction scenario and related algorithms for QoS-guaranteed realtime multimedia session, resource reservation and connection establishment are explained and analyzed. From the experimental implementation of the proposed scheme on a small scale BcN testbed, we verified that the proposed architecture is applicable for the realtime multimedia service provisioning. We analyze the network performance and QoS parameters in detail.