• Title/Summary/Keyword: interaction parameters

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Effect of pH on the sorption kinetics of chlorophenols onto HDTMA-montmorillonite (염화페놀류 화합물의 HDTMA-montmorillonite에 대한 수착 동력학에 미치는 ph의 영향)

  • Mun Yong, Gwak;Dong Ik, Song
    • Proceedings of the Korean Society of Soil and Groundwater Environment Conference
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    • 2004.04a
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    • pp.186-191
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    • 2004
  • Sorption kinetics of 2-chlorophenol(2-ChP), 2,4-dichlorophenol(2,4-DChP) and 2,4,5-trichlorophenol (2,4,5-TChP), onto montmorillonite modified with hexadecyltrimethyl ammonium cations(HDTMA-mont) were investigated. One-site mass transfer model(OSMTM) and two compartment first-order kinetic model(TCFOKM) were used to analyze kinetics. As expected from the number of model parameters involved, the three-parameter TCFOKM was better than the two-parameter OSMTM in describing sorption and desorption kinetics of chlorophenols in HDTMA-mont. For all chlorophenols, the results of OSMTM analysis indicate that the predominant deprotonated speciation(at pH 9.15) exhibited higher mass transfer coefficient( $k_{s}$ ) than the protonated speciation(at pH 4.85). This is because the deprotonated speciation has stronger hydrophobic interaction than protonated speciation. Most sorption completes in three hours. The fraction of the fast sorption and the first-order sorption rate constants for the fast and slow compartments in TCFOKM were determined by fitting experimental data to the TCFOKM. The results of kinetics reveal that the fraction of the fast sorption( $f_1$) and the sorption rate constants in the fast compartments( $k_1$) were in the order 2,4,5-TChP > 2,4-DChP > 2-ChP, which agrees with the magnitude of the $K_{ow}$ . The first-order sorption rate constants in the fast compartment(10$^{0.8}$ - 10$^{1.22}$ h $r^{-1}$ ) were much larger than those in the slow compartment(10$^{-1}$.74/ - 10$^{-2}$.622/ h $r^{-1}$ ).> ).).

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Real Time Gaze Discrimination for Human Computer Interaction (휴먼 컴퓨터 인터페이스를 위한 실시간 시선 식별)

  • Park Ho sik;Bae Cheol soo
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.30 no.3C
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    • pp.125-132
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    • 2005
  • This paper describes a computer vision system based on active IR illumination for real-time gaze discrimination system. Unlike most of the existing gaze discrimination techniques, which often require assuming a static head to work well and require a cumbersome calibration process for each person, our gaze discrimination system can perform robust and accurate gaze estimation without calibration and under rather significant head movement. This is made possible by a new gaze calibration procedure that identifies the mapping from pupil parameters to screen coordinates using generalized regression neural networks (GRNNs). With GRNNs, the mapping does not have to be an analytical function and head movement is explicitly accounted for by the gaze mapping function. Futhermore, the mapping function can generalize to other individuals not used in the training. To further improve the gaze estimation accuracy, we employ a reclassification scheme that deals with the classes that tend to be misclassified. This leads to a 10% improvement in classification error. The angular gaze accuracy is about 5°horizontally and 8°vertically. The effectiveness of our gaze tracker is demonstrated by experiments that involve gaze-contingent interactive graphic display.

Effects of Various Field Coccidiosis Control Programs on Host Innate and Adaptive Immunity in Commercial Broiler Chickens

  • Lee, Kyung-Woo;Lillehoj, Hyun S.;Jang, Seung-I.;Lee, Sung-Hyen
    • Korean Journal of Poultry Science
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    • v.39 no.1
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    • pp.17-25
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    • 2012
  • Coccidiosis control programs such as vaccines or in-feed anticoccidials are commonly practiced in the poultry industry to improve growth performance and health of commercial broiler chickens. In this study, we assessed the effects of various coccidiosis control programs (e.g., in ovo vaccination, synthetic chemicals, and antibiotic ionophores) on immune status of broiler chickens vaccinated against infectious bronchitis virus and Newcastle disease virus (ND) and raised on an Eimeria-contaminated used litter. In general, the levels of ${\alpha}$-1-acid glycoprotein, an acute phase protein, were altered by the treatments when measured at 34 days of age. Splenocyte subpopulations and serum antibody titers against ND were altered by various coccidiosis control programs. In-ovo-vaccinated chickens exhibited highest mitogenic response when their spleen cells were stimulated with concanavalin A (Con A) at 7 days of age. It is clear from this study that the type of coccidiosis control program influenced various aspects of innate and adaptive immune parameters of broiler chickens. Further studies will be necessary to delineate the underlying relationship between the type of coccidiosis control program and host immune system and to understand the role of other external environmental factors such as gut microbiota on host-pathogen interaction in various disease control programs.

Resonance Characteristics of Fruits in Packaging System for Parcel Delivery Service (택배용 포장시스템이 적용된 과실의 공진특성)

  • Jung, Hyun Mo;Kim, Su Il
    • KOREAN JOURNAL OF PACKAGING SCIENCE & TECHNOLOGY
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    • v.21 no.3
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    • pp.91-96
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    • 2015
  • Fruit and vegetables are subjected to complex dynamic stresses in the transportation environment. During a long journey from the production area to customers using parcel delivery service, there is always some degree of vibration present. Vibration inputs are transmitted from the vehicle through the packaging to the fruit. Inside, these cause sustained bouncing of fruits against each other and container wall. These steady state vibration input may cause serous fruit injury, and this damage is particularly severe whenever the fruit inside the package is free to bounce, and is vibrated at its resonance frequency. The determination of the resonance frequencies of the fruit and vegetables may help the packaging designer to determine the proper packaging system providing adequate protection for the fruit, and to understand the complex interaction between the components of fruit when they relate to expected transportation vibration inputs. Instrumentation and technologies are described for determining the vibration response characteristics of the fruits with frequency range 3 to 150 Hz. The resonance frequency of the pear ranged from 53 to 102 Hz and the amplitude at resonance was between 1.08 and 2.48 G. The resonance frequency and amplitude at resonance decreased with the increase of the sample mass, and they were slightly affected by mechanical properties such as bioyield deformation and rupture deformation. Regression analysis was performed among the relatively high correlated parameters from the results of correlation coefficient analysis.

Homology modeling of the structure of tobacco acetolactate synthase and examination of the model by site-directed mutagenesis

  • Le, Dung Tien;Yoon, Moon-Young;Kim, Young-Tae;Choi, Jung-Do
    • Proceedings of the Korean Society for Bioinformatics Conference
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    • 2003.10a
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    • pp.277-287
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    • 2003
  • Acetolactate synthase (ALS, EC 4.1.3.18; also referred to as acetohydroxy acid synthase) catalyzes the first common step in the biosynthesis of valine, leucine, and isoleucine in microorganisms and plants. Recently X-ray structure of yeast ALS was available. Pair-wise alignment of yeast and tobacco ALS sequences revealed 63% sequence similarity. Using Deep View and automatic modeling on Swiss model server, we have generated reliable models of tobacco ALS based on yeast ALS template with a calculated pair-wise RMSD of 0.86 Angstrom. Functional roles of four residues located on the subunit interface (H142, El43, M350, and R376) were examined by site-directed mutagenesis. Seven mutants were generated and purified, of which three mutants (H142T, M350V, and R376F) were found to be inactivated under various assay conditions. The H142k mutant showed moderately altered kinetic properties. The E143A mutant increased 10-fold in K$_m$ value while other parameters remained unchanged. The M350C mutant was strongly resistant to three tested herbicides, while the R376k mutant can bind with herbicide carder at similar affinity to that of wild type enzyme, as determined by tryptophan quenching study. Except M350V mutant, all other mutants were ate to bind with cofactor FAD. Taken together, it is likely that residues H142 and E143 are located at the active site, while residues M350 and R376 are possibly located at the overlapping region of active site and herbicide binding site of the enzyme. Our data also allows us to hypothesize that the interaction between side chains of residues M350 and R376 are probably essential for the correct conformation of the active site. It remains to be elucidated that, whether the herbicide, upon binding with enzyme, inactivates the enzyme by causing change in the active site allosterically, which is unfavorable for catalytic activity.

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COMPUTATIONAL SIMULATION OF FIRE SUPPRESSION SYSTEM FOR CABINS OF SHIPBOARD ENCLOSURE (선박 거주구역용 소화시스템의 전산 시뮬레이션)

  • Jung, I.S.;Chung, H.T.;Han, Y.S.
    • Journal of computational fluids engineering
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    • v.21 no.4
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    • pp.40-45
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    • 2016
  • The numerical simulation has been performed to predict the performance of the fire suppression system for cabin of shipboard enclosure. The present study aims ultimately at finding the optimal parametric conditions of the mist-injecting nozzles using the CFD methods. The open numerical code was used for the present simulation named as FDS (Fire Dynamics Simulator). Application has been done to predict the interaction between water mist and fire plume. In this study, the passenger cabin was chosen as simulation space. The computational domains for simulation in the passenger cabin were determined following the fire scenario of IMO rules. The full scale of the flow field is $W{\times}L{\times}H=4{\times}3{\times}2.4m^3$ with a dead zone of $W{\times}L{\times}H=1.22{\times}1.1{\times}2.4m^3$. The water mist nozzle is installed in ceiling center of 2.3 m height from the floor, and there are six mattresses and four cushions in the simulation space. The combination patterns of orifices to the main nozzle and the position to install nozzles were chosen as the simulation parameters for design applications. From the present numerical results, the centered-located nozzles having evenly combined orifices were shown as the best performance of fire suppression.

EFFECT OF VALVE TIMING AND LIFT ON FLOW AND MIXING CHARACTERISTICS OF A CAI ENGINE

  • Kim, J.N.;Kim, H.Y.;Yoon, S.S.;Sa, S.D.;Kim, W.T.
    • International Journal of Automotive Technology
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    • v.8 no.6
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    • pp.687-696
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    • 2007
  • To increase the reliability of auto-ignition in CAI engines, the thermodynamic properties of intake flow is often controlled using recycled exhaust gases, called internal EGR. Because of the internal EGR influence on the overall thermodynamic properties and mixing quality of the gases that affect the subsequent combustion behavior, optimizing the intake and exhaust valve timing for the EGR is important to achieve the reliable auto-ignition and high thermal efficiency. In the present study, fully 3D numerical simulations were carried out to predict the mixing characteristics and flow field inside the cylinder as a function of valve timing. The 3D unsteady Eulerian-Lagrangian two-phase model was used to account for the interaction between the intake air and remaining internal EGR during the under-lap operation while varying three major parameters: the intake valve(IV) and exhaust valve(EV) timings and intake valve lift(IVL). Computational results showed that the largest EVC retardation, as in A6, yielded the optimal mixing of both EGR and fuel. The IV timing had little effect on the mixing quality. However, the IV timing variation caused backflow from the cylinder to the intake port. With respect to reduction of heat loss due to backflow, the case in B6 was considered to present the optimal operating condition. With the variation of the intake valve lift, the A1 case yielded the minimum amount of backflow. The best mixing was delivered when the lift height was at a minimum of 2 mm.

Theoretical solutions for displacement and stress of a circular opening reinforced by grouted rock bolt

  • Zou, Jin-Feng;Xia, Zhang-Qi;Dan, Han-Cheng
    • Geomechanics and Engineering
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    • v.11 no.3
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    • pp.439-455
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    • 2016
  • This paper presented solutions of displacement and stress for a circular opening which is reinforced with grouted rock bolt. It satisfies the Mohr-Coulomb (M-C) or generalized Hoek-Brown (H-B) failure criterion, and exhibits elastic-brittle-plastic or strain-softening behavior. The numerical stepwise produce for strain-softening rock mass reinforced with grouted rock bolt was developed with non-associative flow rules and two segments piecewise linear functions related to a principle strain-dependent plastic parameter, to model the transition from peak to residual strength. Three models of the interaction mechanism between grouted rock bolt and surrounding rock proposed by Fahimifar and Soroush (2005) were adopted. Based on the axial symmetrical plane strain assumption, the theoretical solution of the displacement and stress were proposed for a circular tunnel excavated in elastic-brittle-plastic and strain-softening rock mass compatible with M-C or generalized H-B failure criterion, which is reinforced with grouted rock bolt. It showed that Fahimifar and Soroush's (2005) solution is a special case of the proposed solution for n = 0.5. Further, the proposed method is validated through example comparison calculated by MATLAB programming. Meanwhile, some particular examples for M-C or generalized H-B failure criterion have been conducted, and parametric studies were carried out to highlight the influence of different parameters (e.g., the very good, average and very poor rock mass). The results showed that, stress field in plastic region of surrounding rock with considering the supporting effectiveness of the grouted rock bolt is more than that without considering the effectiveness of the grouted rock bolt, and the convergence and plastic radius are reduced.

Bending of a rectangular plate resting on a fractionalized Zener foundation

  • Zhang, Cheng-Cheng;Zhu, Hong-Hu;Shi, Bin;Mei, Guo-Xiong
    • Structural Engineering and Mechanics
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    • v.52 no.6
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    • pp.1069-1084
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    • 2014
  • The long-term performance of plates resting on viscoelastic foundations is a major concern in the analysis of soil-structure interaction. As a powerful mathematical tool, fractional calculus may address these plate-on-foundation problems. In this paper, a fractionalized Zener model is proposed to study the time-dependent behavior of a uniformly loaded rectangular thin foundation plate. By use of the viscoelastic-elastic correspondence principle and the Laplace transforms, the analytical solutions were obtained in terms of the Mittag-Leffler function. Through the analysis of a numerical example, the calculated plate deflection, bending moment and foundation reaction were compared to those from ideal elastic and standard viscoelastic models. It is found that the upper and lower bound solutions of the plate response estimated by the proposed model can be determined using the elastic model. Based on a parametric study, the impacts of model parameters on the long-term performance of a foundation plate were systematically investigated. The results show that the two spring stiffnesses govern the upper and lower bound solutions of the plate response. By varying the values of the fractional differential order and the coefficient of viscosity, the time-dependent behavior of a foundation plate can be accurately captured. The fractional differential order seems to be dependent on the mechanical properties of the ground soil. A sandy foundation will have a small fractional differential order while in order to simulate the creeping of clay foundation, a larger fractional differential order value is needed. The fractionalized Zener model is capable of accounting for the primary and secondary consolidation processes of the foundation soil and can be used to predict the plate performance over many decades of time.

Evaluation of rock load based on critical shear strain concept on tunnels (한계전단변형률 개념을 이용한 터널의 지반이완하중 평가)

  • Kim, Jung-Joo;Lee, Jae-Kook;Kim, Jong-Uk;Yoo, Han-Kyu
    • Journal of Korean Tunnelling and Underground Space Association
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    • v.15 no.6
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    • pp.637-652
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    • 2013
  • After studying the characteristics of three different evaluation methods of rock load; namely theoretical method, empirical method and numerical method, there were too many limitations for them to be applied on tunnels. Therefore, in this research paper, the method based on numerical analysis is selected to use as this method is the most reasonable one since it considers all parameters that are necessary for rock load estimations, and it also considers the interaction between ground and tunnel support. The critical shear strain concept formulated by Sakurai (1981) was used in order to measure exact rock load values based on numerical analysis. Evaluation on a Level 1 rock load height, which is depicted by the stable region in the graph shows that rock load is not affecting between ground grade 1~3, and it was evaluated that the fourth and fifth grades show less values of rock load height which led to the conclusion of a more economical design of concrete lining.