• PNF and Movement
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• v.10 no.2
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• pp.33-39
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• 2012

Purpose : The purpose of this case report was to examine the effects of intergrative intervention approach on a patient with lumbar herniated nucleus pulposus (HNP). Methods : The subject was a 53 years old woman with lumbar HNP. The subject received conventional physical therapy combined with exercise therapy and manual therapy. Pain on visual analog scale (VAS), finger to floor (FTF), lumbar lateral flexion, L5 motor, and straight Leg-Raising (SLR) were evaluated at baseline and after 4 weeks. Results : The change of VAS, FTF, left lateral flexion, and right lateral flexion were decreased (9 vs. 5, 41 vs, 25, 56 vs. 42, 54 vs. 41, respectively) and the change of L5 motor and SLR were increased (Fair vs. Fair+, 60 vs. 75, respectively). Conclusion : Our findings suggest that Integrative intervention may be considered in patient with lumbar HNP.

• The Journal of Korean Medicine
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• v.42 no.1
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• pp.119-128
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• 2021

Objectives: This is a five-year survival case report on non-small cell lung cancer (NSCLC) treated with western medicine and traditional Korean medicine. 44-year old man diagnosed NSCLC IIIB in 2015 went through two months' concurrent chemoradiotherapy (CCRT) first, however the cancer did not response. After CCRT he began to take intensive integrative therapy including acupuncture, abdominal moxibustion, wild ginseng pharmacopuncture, herbal medicinal product of ginseng, hyperthermia, Thymosin α1, and mega vitamin C injection for 4 years and 9 months. After three months of intensive treatment, the state of cancer changed first to partial response and then complete response. He finally succeeded in five-year survival without any recurrence or complication in 2020, We suggest that integrative approach including traditional Korean medicine can be a meaningful treatment option for nonoperable NSCLC. Further studies with more cases should be performed to establish proper treatment protocol of integrative medicine for lung cancer.

• Journal of Pharmaceutical Investigation
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• v.40 no.6
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• pp.333-337
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• 2010

Combining cell- and gene-based therapy is a promising therapeutic strategy in regenerative medicine. The aim of this study was to develop genetically modified mesenchymal stem cell (MSC) aggregates using a poly(ethylene glycol) (PEG) hydrogel micro-well array technique. Stable PEG hydrogel micro-well arrays with diameters of 200 to $500\;{\mu}m$ were fabricated and used to generate genetically engineered MSC aggregates. Rat bone marrow-derived MSCs were transfected with a green fluorescent protein (GFP) plasmid as a reporter gene, and aggregated by culturing in the PEG hydrogel micro-well arrays. The resultant cell aggregates had a mean diameter of less than $200\;{\mu}m$, and maintained the mesenchymal phenotype even after genetic modification and cell aggregation. Transplantation of MSC aggregates that are genetically modified to express therapeutic or cell-survival genes may be a potential therapeutic approach for regenerative medicine.

• Journal of Korean Biological Nursing Science
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• v.25 no.1
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• pp.8-19
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• 2023

Purpose: The purpose of this study was to analyze the experiences and perceptions of nursing students related to their cadaver practice through an integrative review. Methods: An integrative review was conducted using Whittemore and Knafl's framework published in 2005. The key words, "nursing students & cadaver" and "nursing students & anatomy" were used to search peer-reviewed publications in six databases. Among 373 searched articles, 15 articles were selected after excluding articles that did not meet the inclusion criteria. The literature quality was moderate (levels C and B). Results: The results from the 15 selected studies were integrated and classified into seven themes: "anxiety and discomfort," "gratitude and respect for donors," "dignity of the human body and life," "acceptance of death," "getting closer to the nursing profession," "enhanced understanding and memory of the human body" and "enhancement of learning motivation." Conclusion: In conclusion, cadaver practice provided an opportunity to form values about the dignity of life and death, helped nursing students understand the human body, and motivated them to approach the profession of nursing. It is suggested to develop integrated cadaver practice programs that incorporate bioethics, spiritual nursing, and the vocation of the nursing profession.

• Structural Engineering and Mechanics
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• v.52 no.4
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• pp.739-753
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• 2014

There have been many packages that can be employed to analyze plane frames. However, because most structural analysis packages suffer from closeness of system, it is very difficult to integrate it with an optimization package. To overcome the difficulty, we proposed a possible alternative, DAMDO, which integrate Design, Analysis, Modeling, Definition, and Optimization phases into an integrative environment. The DAMDO methodology employs neural networks to integrate structural analysis package and optimization package so as not to need directly to integrate these two packages. The key problem of the DAMDO approach is how to generate a set of reasonable random designs in the first phase. According to the characteristics of optimized plane frames, we proposed the ratio variable approach to generate them. The empirical results show that the ratio variable approach can greatly improve the accuracy of the neural networks, and the plane frame optimization problems can be solved by the DAMDO methodology.

• Clinical and Experimental Pediatrics
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• v.54 no.12
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• pp.481-488
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• 2011

In the current era of low-birth rate in Korea, it is important to improve our neonatal intensive care and to establish an integrative system including a regional care network adequate for both high-risk pregnancies and high-risk newborn infants. Therefore, official discussion for nation-wide augmentation, proper leveling, networking, and regionalization of neonatal and perinatal care is urgently needed. In this report, I describe the status of neonatal intensive care in Korea, as well as nationwide flow of transfer of high-risk newborn infants and pregnant women, and present a short review of the regionalization of neonatal and perinatal care in the Unites States and Japan. It is necessary not only to increase the number of neonatal intensive care unit (NICU) beds, medical resources and manpower, but also to create a strong network system with appropriate leveling of NICUs and regionalization. A systematic approach toward perinatal care, that includes both high-risk pregnancies and newborns with continuous support from the government, is also needed, which can be spearheaded through the establishment of an integrative advisory board to propel systematic care forward.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2012.04a
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• pp.132-137
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• 2012

To enhance the CAE accuracy, the definition of material behavior is one of key influence on the result. In case of plastic material with fiber reinforcement, the anisotropic material behavior should be taken into account to increase of CAE accuracy. BASF has developed an innovative CAE tool, ULTRASIM$^R$, which is capable of generating material models of thermoplastic materials for structural simulation. ULTRASIM$^R$, not only the glass fiber orientation effect, but also the weld line effect, tensile-compression anisotropy, strain rate effect are combined in a non-linear material law, which will be evaluated in a unique failure criterion, thus resulting in an highly accurate CAE approach.

• Journal of the Korean Home Economics Association
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• v.37 no.12 s.142
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• pp.179-192
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• 1999

Thesedays, Home Economic in Korea is faced with the danger of a discord caused by the outer pressure of reorganization in the process educational reformation. The first purpose of this study was to examine the characteristics of the informatized society and the changes of families lived in the informatized society. The second was to assert to strengthen Home Economics in the informatized society. Ultimately we suggested an integrative and interdisciplinary model about Home Economics from the ecological and informative perspective. This model consist with three parts: Human development(Child studies, Gerontology, & Adolescent studies) and family studies division(Family relation studies, family resource management studies, & Consumer studies) Environmental division(Clothing and Textiles, Food and Nutrition, & Housing) and HEIS(Home Economics Information System). This classification is correspond with the one Human-Behavioral Environment and Human-Constructed Environment of Ecological theory.

• Journal of Ginseng Research
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• v.46 no.2
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• pp.183-187
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• 2022

The current Covid-19 pandemic has changed the entire world and bought so many unprecedented challenges to the scientific community. More than 5 million people died due to the SARS-COV-2 outbreak. For many thousands of years, ginseng, the traditional herb has been used for various infectious diseases by traditional healers. Ginseng showed promising antiviral effects by modulating both natural and acquired immunity. Ginseng might be used as a potential therapeutic agent to prevent SARS-CoV-2 infection along with the vaccine. In this current review, we offer an alternative approach for SARS-COV-2 prevention during this unprecedented pandemic.

• Journal of The Korean Society of Integrative Medicine
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• v.10 no.3
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• pp.73-84
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• 2022

Background : Lymphedema is a progressive disorder characterized by the impairment of lymph flow from tissues to the blood circulation system. This occurs as a result of damage to the lymphatic system. Complex decongestive therapy (CDT) is a multimodal, conservative therapeutic approach that is used for the management of lymphedema. CDT consists of a combination of compression therapy, manual lymphatic drainage, exercise, and skin care. Purpose : This study aimed to provide a review of available physical therapy interventions as well as general care guidelines for patients with lymphedema. Methods : The recommendations and guidelines for physical therapy management, medical management, and general information were reviewed from the following sources: 1) The American Physical Therapy Association, 2) The Norton School of Lymphatic Therapy, and 3) The International Society of Lymphology. This review contains general information, including the medical management and the importance of physical therapy in lymphedema. Physical therapy management should be based on an assessment of the patients' presenting impairments, including based on inclusion or exclusion of physical therapy interventions. This review also outlines a step-by-step approach that starts with disease diagnosis and progression all the way through to rehabilitation as an outpatient. Conclusion : Depending on the patients' journey to recovery and the requirement for rehabilitation, physical therapy interventions should focus on the patients' needs including pain, appearance, physical function and general rehabilitation. We hope that this review will provide information on evidence-based physical therapy and general care to patients with lymphedema.