• Proceedings of the Korean Operations and Management Science Society Conference
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• 1996.04a
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• pp.121-124
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• 1996

In general, cellular manufacturing system can be constructed by the following two steps. The first step forms machine cells and part families, and the second step determines cell layout based on the result of first step. Cell layout has to be considered when cell is formed becauese the result of cell formation affects it. This paper presents a cell formation algorithm and proposes an integrated mathematical model for cell formation and cell layout. The cell formation algorithm minimizes the number of exceptional element in cellular manufacturing system. New concept for similarity and incapability is introduced, based on machine-operation incidence matrix and part-operation incidence matrix. One is similarity between the machines, the other is similarity between preliminary machine cells and machines. The incapability identifies relations between machine cells and parts. In this procedure, only parts without an exceptional element are assigned to machine cell. Bottleneck parts are considered with cell layout design in an integrated mathematical model. The integrated mathematical model determines cell layout and assigns bottleneck parts to minimize the number of exceptional element and intercell moving distance, based on linearixed 0-1 integer programming. The proposed algorithm is illustrated by using numerical examples.

• Environmental Sciences Bulletin of The Korean Environmental Sciences Society
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• v.2 no.1
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• pp.21-28
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• 1998

A total of 94 taxa were identified from the Southern Ocean, 140-148 $^{\circ}E$ and 40-53 $^{\circ}S$, as an early austral summer phytoplankton. They were 53 diatoms, 37 dinoflagellates, 2 silicoflagellates, 1 prymnesiophyte, and 1 coccolithophorid. Integrated cell numbers of nanoplankton dominated microphytoplankton from 8 stations, especially from Subantarctic zone, but integrated biomass was lower than microphytoplankton. Integrated cell numbers of diatoms dominated dinoflagellates, coccolithophorids, and prymnesiophyte, but integrated biomass of microphytoplankton were dependent to the biomass of dinoflagellates except north of the Subtropical convergence zone and south of the Antractic convergence zone. Phytoplankton community changed across the fronts and 3 different communities were observed. Fronts seem to influence on the phytoplankton community from the west Pacific Sector of the Southern Ocean.

• Journal of Environmental Science International
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• v.2 no.1
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• pp.21-28
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• 1993

A total of 94 taxa were identified from the Southern Ocean, 140-148 。E and 40-53。S, as an early austral summer phytoplankton. They were 53 diatoms, 37 dinoflagellates, 2 silicoflagellates, 1 prymnesiophyte, and 1 coccolithophorid. Integrated cell numbers of nanoplankton dominated microphytoplankton from 8 stations, especially from Subantarctic zone, but integrated biomass was lower than microphytoplankton. Integrated cell numbers of diatoms dominated dinoflagellates, coccolithophorids, and pnrnnesiophyte, but integrated biomass of microphytoplankton were dependent to the biomass of dinoflagellates except north of the Subtropical convergence zone and south of the Antractic convergence sone. Phytoplankton community changed across the fronts and 3 different communities were observed. Fronts seem to influence on the phytoplankton community from the west Pacific Sector of the Southern Ocean.

• Korean Management Science Review
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• v.12 no.1
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• pp.1-17
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• 1995

The success of cell manufacturing applications in FMS rests on the effective cell formation to maintain the independent relations both between machine cells and between part families. This paper presents an integrated method for concurrent formation of cells and families with no E.E (Exceptional Element) in FMS with alternative routings. To determine the maximum number of cell and family with no E.E, mathematical conditions and properties are derived. New concept of nonsimilarity is introduced for each machine and part based on machine-operation incidence matrix and part-operation incidence matrix. To concurrently form the cells and families, integer programming based mathematical models are developed. For the predetermined number of cell or family, model I is used to identify whether E.E exists or not. Model II forms cells and families considering only nonsimilarity. But model III can consider nonsimilarity and processing times. The proposed method is tested and proved by using numerical examples.

• Journal of the Korean Operations Research and Management Science Society
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• v.25 no.1
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• pp.85-92
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• 2000

Channel management is critical in designing a cellular mobile system that offers high capacity and high quality. In this paper, an integrated channel management scheme is proposed, which consists of a dynamic channel allocation scheme and an admission control scheme. The dynamic channel allocation scheme allocates a call request the channel which minimizes the impact on its interfering cell, and consists of two types of channel allocation strategies : nominal channel allocation strategy and non-nominal channel allocation strategy. The admission control scheme named the variable cutoff priority scheme reserves some frequency channels for handoff cells in each cell the number of which varies according to the blocking probability of handoff class in that cell. Computationl tests are performed to evaluate the performance of the proposed scheme in terms of overall blocking probability, defined by the weighted value of the blocking probabilities of new calls and handoff calls. The results show that the proposed scheme yields better performance than other compared schemes.

• Plant Biotechnology Reports
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• v.2 no.1
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• pp.13-20
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• 2008

Potato (Solanum tuberosum L.), one of the most important food crops, is susceptible to a number of devastating fungal pathogens in addition to bacterial and other pathogens. Producing disease-resistant cultivars has been an effective and useful strategy to combat the attack of pathogens. Potato was transformed with Agrobacterium tumefaciens strain EHA101 harboring chitinase, (ChiC) isolated from Streptomyces griseus strain HUT 6037 and bialaphos resistance (bar) genes in a binary plasmid vector, pEKH1. Polymerase chain reaction (PCR) analysis revealed that the ChiC and bar genes are integrated into the genome of transgenic plants. Different insertion sites of the transgenes (one to six sites for ChiC and three to seven for bar) were indicated by Southern blot analysis of genomic DNA from the transgenic plants. Expression of the ChiC gene at the messenger RNA (mRNA) level was confirmed by Northern blot analysis and that of the bar gene by herbicide resistance assay. The results obviously confirmed that the ChiC and bar genes are successfully integrated and expressed into the genome, resulting in the production of bialaphos-resistant transgenic plants. Disease-resistance assay of the in vitro and greenhouse-grown transgenic plants demonstrated enhanced resistance against the fungal pathogen Alternaria solani (causal agent of early blight).

• Genomics & Informatics
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• v.9 no.4
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• pp.173-180
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• 2011

Recent trends in generating multiple, large-scale datasets provide new challenges to manipulating the relationship of different types of components, such as gene expression and drug response data. Integrative analysis of compound response and gene expression datasets generates an opportunity to capture the possible mechanism of compounds by using signature genes on diverse types of cancer cell lines. Here, we integrated datasets of compound response and gene expression profiles on NCI60 cell lines and constructed a network, revealing the relationship for 801 compounds and 341 gene probes. As examples, obtusol, which shows an exclusive sensitivity on a small number of colon cell lines, is related to a set of gene probes that have unique overexpression in colon cell lines. We also found that the SLC7A11 gene, a direct target of miR-26b, might be a key element in understanding the action of many diverse classes of anticancer compounds. We demonstrated that this network might be useful for studying the mechanisms of varied compound response on diverse cancer cell lines.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.22 no.51
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• pp.89-97
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• 1999

Recently, due to the rapid technological progress, CDMA cellular system is widely used for voice, data and multimedia services. But the analysis for voice-data integrated traffic has not been done satisfactorily. Moreover, there is few research results for voice-data integrated traffic. In this paper, we propose an effective channel allocation algorithm for CDMA cellular system which serves voice-data integrated traffic. As for the proposed channel allocation algorithm, new calls and hand-off calls first attempt to connect micro-cell. We model the channel allocating scheme as a Birth-and-Death process. We reserve a few hand-off dedicated channels and calculate the blocking probability of hand-off calls varying the number of hand-off dedicated channels. Then we decide the number of hand-off dedicated channels satisfying the proper QoS(Quality of Service) and minimum blocking probability.

• 제어로봇시스템학회:학술대회논문집
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• 2003.10a
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• pp.2441-2444
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• 2003

This paper describes fabrication of a micro cell counter integrated with an oxygen micropump and Sephadex G-25 beads counting experiment. The device utilized a phototransistor, microwindow, and light source of microscope for beads detection. Microheater and microchannel were used for pumping and guiding of beads to the microwindow. Counting capability of the device was tested with a peristaltic pump and the measured signals (${\sim}10\;mV$) with oscilloscope showed peak shape when beads passed the microwindow. Pumping of beads by the oxygen micropump was carried out by heating paraffin, which enveloped manganese dioxide (catalyst), to trigger the decomposition of hydrogen peroxide into water and oxygen. It lasted for 5 min with $7\;{\mu}l$ of wt. 30 % hydrogen peroxide. Beads counting by oxygen micropump showed peaks ($2{\sim}20\;mV$) with $30\;{\mu}l$ of beads sample and the number of peaks by magnitude was acquired.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.28 no.2
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• pp.94-100
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• 2005

This paper presents the application of integrated mathematical programming approach for the design of cellular manufacturing. The proposed approach is carried out in two phases The first phase concerning exceptional elements(EEs) in cell formation and the second phase facilities layout design. This paper considers the total costs of three important costs for (1) intercellular transfer (2) machine duplication and (3) subcontracting. One of Important issue is the calculation of the number of machines considering the maximum utilization of machines and the available capacity of a machines that can be transferred between cells. Facilities layout design is considered to reflect the real field data taking in to account the operational sequence of the parts to be manufactured. The model is formulated as mixed integer programming that is employed to find the optimal solution.