• Title/Summary/Keyword: initial permeability

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Antifilarial potential of the root extracts of Mirabilis jalapa Linn. (Nyctaginaceae) on cattle filarial parasite Setaria cervi

  • Uddin, Qamar;Parveen, N.;Khan, Nizam U.;Zaidi, SM Kashif R.;Singhal, KC.
    • Advances in Traditional Medicine
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    • v.3 no.4
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    • pp.180-186
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    • 2003
  • Effect of aqueous and alcoholic extracts of the roots of Mirabilis jalapa Linn. Four Oclock plant, on the spontaneous movements of both the whole worm and the nerve-muscle (n.m.) preparation of Setaria cervi and on the survival of microfilariae in vitro was studied. Alcoholic extract caused the inhibition of spontaneous movements of the whole worm and the n.m. preparation of S. cervi, whereas aqueous extract caused inhibition of spontaneous movements of the n.m. preparation. The initial stimulatory effect was not observed by aqueous and alcoholic extracts on n.m. preparation while effect of alcoholic extract on the whole worm was characterized by an increase in the amplitude of contractions followed by reversible paralysis. The concentrations required to inhibit the movements of the whole worm and n.m. preparation for alcoholic extract of root were $270\;{\mu}g/mL$ and $40\;{\mu}g/mL$, respectively whereas an aqueous extract caused inhibition of n.m. preparation at $30\;{\mu}g/mL$ suggesting a cuticular permeability barrier. Alcoholic extract of the roots of M. jalapa caused concentration related effect on the survival of microfilariae of S. cervi. The $LC_{50}$ and $LC_{90}$ for alcoholic extract as observed after 6 hrs. were found to be 10 ng/mL and 18 ng/mL., respectively.

Development of Methodology for Fracture Network Analysis in the Unsaturated Zone using MINC Approach in TOUGH2 Code (TOUGH2 전산코드의 MINC 기법을 이용한 불포화 암반 내 단열 해석 방법론 개발)

  • Ha, Jaechul;Cheong, Jae-yeol;Kim, Soogin;Yoon, Jeonghyoun
    • The Journal of Engineering Geology
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    • v.26 no.3
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    • pp.325-330
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    • 2016
  • The second phase of low- and intermediate-level waste (LILW) disposal facility is under planned on the sedimentary rock in unsaturated zone. In this study, we created two meshes which were a matrix continuum mesh and a fracture continuum mesh to carry out 2 dimensional numerical modeling for groundwater flow in the unsaturated zone containing fractures focused on the second phase of LILW disposal facility. Two continuum meshes were developed using MINC in meshmaker module of TOUGH2 code. A fracture continuum mesh was included the k-field distribution of the permeability derived from the Discrete Fractured Network (DFN) modeling. To apply the unsaturated zone for the modeling, the gridding steps to generate mesh were developed. Each step to generate a mesh consisted of definition of materials, setting the initial conditions and creating grids using MINC. The methodology development of meshes in this study will be applied for more precise modeling of groundwater flow and mass transport.

Comparison of Characteristics and Performance of Membrane in Proton Exchange Membrane Fuel Cells (고분자전해질 연료전지 고분자막의 특성 및 성능 비교)

  • Lee, Daewoong;Lim, Daehyun;Oh, Sohyeong;Chung, Hoi-Bum;Yoo, Seung-Eul;Ku, Young-Mo;Park, Kwonpil
    • Korean Chemical Engineering Research
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    • v.58 no.2
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    • pp.171-175
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    • 2020
  • In the proton exchange membrane fuel cells (PEMFC), the development of a reinforced membrane with improved durability by a support is actively in progress in Korea. In this study, the initial performance and characteristics of four types of reinforced membranes were compared. Reinforced membranes with higher amounts of C-F chains in the polymer membrane showed lower water diffusion coefficients due to the hydrophobicity of the C-F chains. The thicker the polymer membrane, the more the hydrogen permeability decreased and the higher the OCV. Membrane with short resistance below 1.5 Ωcm2 showed OCV below 0.9 V and the lowest performance, so short resistance should be above 3.0 Ωcm2. Compared with the current standard membrane, there was a similar domestic membrane, which could confirm the possibility of localization of PEMFC polymer membrane.

Effect of Air Void and Strength Characteristics with Freezing and Thawing Resistance on High Strength Concrete (고강도(高强度) 콘크리트에서 기포조직(氣泡組織) 및 강도특성(强度特性)이 연결융해저항(連結融解抵抗)에 미치는 영향(影響))

  • Kim, Saeng Bin;Moon, Je Kil;Kim, Dong Sin
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.13 no.3
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    • pp.13-24
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    • 1993
  • The influence of the bubble structure and strength characteristics on the freeze-thaw resistance of high strength concrete is investigated by the laboratory experiment. The test conditions are formed in the manner that water is continueusly supplied externally and the specimens were received severe weather actions from ordinary to significantly low temperatures. The experiments are performed in two stages. In the first stage, the relation between the durability to frost action and the bubble structure is analyzed especially with respect to the water-cement ratio and the amount of air. The AE and non-AE concrete specimens made of ordinary portland cement are used in the test. In the second stage, the non-AE concrete specimens using vibratory compaction to improve the durability to frost action, and the high watertight specimens of rapid hardening portland cement to increase their initial strength are produced and tested. The degree of watertightness of the specimens is determined by measuring the permeability of the specimens and the bubble structure of the high watertight concrete is also estimated.

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Three Dimensional Mathematical Simulation for Predicting the Shelf Life of Tofu Packaged in a Semi-rigid Plastic Container (플라스틱 용기 포장 두부의 유통기간 예측을 위한 3차원 수치모사)

  • Kim, Jai-Neung;Lee, Youn-Suk
    • Korean Journal of Food Science and Technology
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    • v.41 no.3
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    • pp.272-277
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    • 2009
  • In this research, three dimensional mathematical models were developed to predict the shelf life of tofu packaged in a semi-rigid plastic container. A model combining oxygen transfer through the package and oxygen consumption within the package was considered. According to the results, the model simulations estimated that the number of microorganisms in the filled water was higher than that in the tofu, suggesting the shelf life of packaged tofu was not affected by the number of microorganisms in the tofu product, but rather by the number of organisms in the filled water. Additionally, the effects of the physical properties of the packaging material, such as oxygen permeability through the package, oxygen diffusion coefficient, the initial oxygen concentration in the filled water, and the depth of the filled water in the packaged tofu, were also observed.

Preparation of the Blends of Poly(amic acid) and PBO Precursor and Their Properties (Poly(amic acid)와 PBO 전구체의 블렌드 제조 및 특성)

  • Yoon, Doo-Soo;Choi, Jae-Kon;Jo, Byung-Wook
    • Polymer(Korea)
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    • v.32 no.1
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    • pp.77-84
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    • 2008
  • The thermal properties, morphology, mechanical properties and gas permeability of the blends of poly (amic acid) (PAA) and poly (o-hydroxyamides) (PHAs) having pendant group was investigated. The 5% weight loss and major weight loss of the b)ends occurred in the ranges of $348{\sim}407^{\circ}C$ and $589{\sim}615^{\circ}C$ upon a heating process. After a thermical annealing, the tensile strength and initial modulus of blends increased $3.7{\sim}52.9%$ and $34.4{\sim}70%$ from the value of pure PAA, respectively. Especially the tensile strength and modulus of the PAA/MP-PHA=9/1 showed the highest values (97.5 MPa and 2.67 GPa, respectively), which were 53 and 70% higher than those of pure PAA. The fine PHA domains were found to be uniformly dispersed. The interfacial adhesion between PAA and PHA was identified to be good. The gas permeabilities of PAA/M-PHA blend increased with M-PHA contents.

Groundwater Flow Analysis Using Finite Difference Method in Volcanic Island (화산도서에서 유한차분법을 이용한 지하수 유동해석)

  • Choe, Yun-Yeong;Lee, Sun-Tak
    • Journal of Korea Water Resources Association
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    • v.33 no.5
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    • pp.611-622
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    • 2000
  • In this study, MODFLOW model is used to analyze the groundwater flow system of Seoguipo area in Cheju island, The final parameters of permeability coefficient and storage coefficient of target area can be obtained by trial and error method using the measured data of pumping rate as initial values. And it is found that the applicability for groundwater flow system is reflected well from the simulation result of the model. Seoguipo area spring water is thought to appear by relatively stable groundwater recharge below EL. 400m according to head distribution through the analysis of observed data considering topographic and geological characteristics, Lee's study(996), and the simulation result. Also it is known that point II, III, and VI show relatively large velocity vectors, and groundwater flows through the movement path which is distributed in various directions of I, II, III, IV, V, VI, and VIl form the result of velocity vector analysis using head distribution result values to analyze the groundwater flow path under unsteady flow condition.dition.

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A Study on the Microwave Absorber Properties of Ni-Cu-Zn Ferrites Composite (Ni-Cu-Zn Ferrite의 복합형 전파흡수체 특성 연구)

  • Min, Eui-Hong;Kim, Moon-Suk;Koh, Jae-Gui
    • Journal of the Korean Magnetics Society
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    • v.17 no.6
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    • pp.238-241
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    • 2007
  • Ni-Cu-Zn ferrites were prepared by the co-precipitation. Physical properties and Microwave absorbing properties were investigated in Ni-Cu-Zn ferrite for the aim of microwave absorbers. From the analysis of X-ray diffraction patterns, we can see that all the particles have only a single phase spinel structure. The loss factor was maximum at sintering temperature $1100^{\circ}C$. The initial permeability of sintered ferrite obtained was an average of 50. We found that the $(Ni_{0.7}Cu_{0.2}Zn_{0.1}O)_{1.02}(Fe_2O_3)_{0.98}$ can be used in ferrite rubber composite microwave absorber when sintering temperature at $1100^{\circ}C$.

Donepezil, Tacrine and $\alpha-Phenyl-n-tert-Butyl Nitrone$ (PBN) Inhibit Choline Transport by Conditionally Immortalized Rat Brain Capillary Endothelial Cell Lines (TR-BBB)

  • Kang Young-Sook;Lee Kyeong-Eun;Lee Na-Young;Terasaki Tetsuya
    • Archives of Pharmacal Research
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    • v.28 no.4
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    • pp.443-450
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    • 2005
  • In the present study, we have characterized the choline transport system and examined the influence of various amine drugs on the choline transporter using a conditionally immortalized rat brain capillary endothelial cell line (TR-BBB) in vitro. The cell-to-medium (C/M) ratio of $[^3{H}]choline$ in TR-BBB cells increased time-dependently. The initial uptake rate of $[^3{H}]choline$ was concentration-dependent with a Michaelis-Menten value, $K_{m}$, of $26.2\pm2.7{\mu}M$. The $[^3{H}]choline$ uptake into TR-BBB was $Na^{+}-independent$, but was membrane potential-dependent. The $[^3{H}]choline$ uptake was susceptible to inhibition by hemicholinium-3, and tetraethy-lammonium (TEA), which are organic cation transporter substrates. Also, the uptake of $[^3{H}]choline$ was competitively inhibited with $K_{i}$ values of $274 {\mu}M, 251 {\mu}M and 180 {\mu}M$ in the presence of donepezil hydrochloride, tacrine and $\alpha-phenyl-n-tert-butyl nitrone$ (PBN), respectively. These characteristics of choline transport are consistent with those of the organic cation transporter (OCT). OCT2 mRNA was expressed in TR-BBB cells, while the expression of OCT3 or choline transporter (CHT) was not detected. Accordingly, these results suggest that OCT2 is a candidate for choline transport at the BBB and may influence the BBB permeability of amine drugs.

Development of Improving Water Quality in Eutrophic Lake Using Microalgal Cultivation (미세조류 배양을 이용한 부영양호 내 수질 개선 기술 개발)

  • Kim, Ki-Hyun;Kang, Sung-Mo;Cho, Yonghee;Jeon, Sanghyun;Kim, Jun-Ho;Park, Hanwool;Lee, Yunwoo;Jeong, Jeongho;Lim, Sang-Min;Lee, Choul-Gyun
    • Journal of Marine Bioscience and Biotechnology
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    • v.10 no.2
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    • pp.91-96
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    • 2018
  • There are many eutrophic lakes by point and non-point pollution sources such as in dustrial waste water, domestic raw sewage, and mucks. The eutrophic lakes not only cause algal blooms but also destroy the ecosystem in the lakes due to high nutrient concentrations. The purpose of this study was to improve water quality in eutrophic lakes by cultivating microalgae using photobioreactors (PBRs) with selectively permeable mesh (SPM), supplying nutrients in the lake and inhibiting cell leakage by diffusion and water permeability. Chlorella vulgaris, was cultivated using PBRs with SPM installed in Inkyung Lake located in Inha university, Incheon, Korea. When cultivating C. vulgaris, $8.3g/m^2/day$ of average biomass productivity was obtained at 3 days. Furthermore, concentrations of total nitrogen and phosphorus were reduced by 35.7% and 84.2%, respectively, compared to initial condition and water quality in eutrophic lake was improved to oligotrophic environment. These results suggest that microalgal cultivation using PBRs with SPM in the lake could produce microalgal biomass as well as improve water quality by decreasing nutrient concentrations.