• Title/Summary/Keyword: inheritance pattern

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Study of Genetic Inheritance in Osmidrosis Patients Based on Pedigree Analysis (가계도 분석을 통한 액취증 유전 경향에 대한 연구)

  • Lee, Jung Woo;Kim, Jeong Tae;Kim, Chang Yeon
    • Archives of Plastic Surgery
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    • v.35 no.5
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    • pp.565-568
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    • 2008
  • Purpose: Bacterial degeneration of sweat and increased secretion of over developed apocrine sweat gland are known causes of osmidrosis. In addition, genetic inheritance must be another important cause, because there are high incidence rates of osmidrosis in familial members. But the research about genetic inheritance has been overlooked. For this reason we studied genetic inheritance in osmidrosis patients based on pedigree analysis. Methods: We have evaluated pedigree of 52 patients who have diagnosed and treated in our hospital from January 2003 to August 2007. For making pedigrees, we have evaluated 3 generations of affected lineage from osmidrosis patients. Family members having uncertain information or those who are before puberty are excluded. In pedigree analysis, inheritance rate and inheritance pattern from parents, prevalence rate in generations and sexual prevalence are evaluated. Results: In this study, we divided pedigrees into 3 different groups according to inheritance pattern. Group A is genetically unrelated pattern with no prevalence between familial members in 7 families. Group B is weakly expressed pattern with 17 families there are genetically related but no genetic patterns are founded. In group B inheritance rate is 34% and incidence rate is 21% in 2nd generation and 22% in 3rd generation. Group C is autosomal dominant pattern with 31 families. In group C, there are no differences in sexual prevalence. Incidence rate is 43% in 2nd generation and 49% in 3rd generation. Conclusion: In this study, we have studied pedigrees of 52 families of osmidrosis patients. 60% of the pedigrees shows autosomal dominant pattern, 33% shows genetically related but no definite autosomal dominant pattern and 7% shows genetically unrelated pattern. In Conclusion, This study can be basic data for future gene analysis study of osmidrosis.

Inheritance of Resistance to Nuclear Polyhedrosis Virus in Silkworm, Bombyx mori

  • Sen, Ratna;Ashwath, S.K.;Datta, R.K.
    • International Journal of Industrial Entomology and Biomaterials
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    • v.3 no.2
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    • pp.187-190
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    • 2001
  • Inheritance pattern of resistance to Bombyx mori nuclear polyhedrosis virus (BmNPV) was studied in an Indian silkworm stock TX by single back-cross test method. The resistant parent [TX], susceptible parent [HM], their Fl, F2, and Fl progeny back-crossed to TX [BC(R)] and HM [BC(S)] were inoculated per os with a fixed concentration of BmNPV($0.5{\times}10^{th} PIB/ml$) on the first day of second stadium. The cumulative mortality was recorded until day $10^{\times}$ post-inoculation. The results show that the resistance to BmNPV in TX fellow mono Mendelian inheritance pattern. The resistance dominated over the susceptibility at Fl. At F2, the resistant and susceptible offspring segregated in 3:1 ratio whereas at BC(S), the resistant and susceptible offspring segregated in 1:1 ratio. The response of BC(R) was more or less like the resistant parent TX which confirms the involvement of a major dominant gene conferring resistance to BmNPV in TX. The possible mechanism of inheritance of resistance in TX is discussed.

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A Tuning Algorithm for the Multidimensional Type Inheritance Index of XML Databases (XML 데이터베이스 다차원 타입상속 색인구조의 조율 알고리즘)

  • Lee, Jong-Hak
    • Journal of Korea Multimedia Society
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    • v.14 no.2
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    • pp.269-281
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    • 2011
  • For the MD-TIX(multidimensional type inheritance index) that supports query processing for the type inheritance concept in XML databases, this paper presents an index tuning algorithm that enhances the performance of the XML query processing according to the query pattern. The MD-TIX uses a multidimensional index structure to support complex XML queries involving both nested elements and type inheritance hierarchies. In this index tuning algorithm, we first determine a shape of index page regions by using the query information about the user's query pattern, and then construct an optimal MD-TIX by applying a region splitting strategy that makes the shape of the page regions into the predetermined one. The performance evaluation results indicate that the proposed tuning algorithm builds an optimal MD-TIX by a given query pattern, and in the case of the three-dimensional query regions for the nested predicates of path length 2, the performance is much enhanced according to the skewed degree of the query region's shape.

Inheritance and expression of transgene in SOD2-Transgenic petunia descendants and their morphological traits

  • Lee, Su-Young;Han, Bong-Hee;Cho, A-Young
    • Journal of Plant Biotechnology
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    • v.36 no.3
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    • pp.289-293
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    • 2009
  • This study was conducted to determine the inheritance and expression of transgene in descendants ($T_1\;to\;T_2$ generation) of SOD2-transgenic petunia by PCR and RT-PCR analysis. The trangene was segregated as Mendelian inheritance pattern (3:1 or 1:0) in most of $T_1\;and\;T_2$ generation lines. Transgenic homozygous lines were obtained in T2 generation. It was identified that the transgene expressed stably in examined all plants of 6 $T_2$ lines. The representative morphological traits (plant height, flower diameter, and flower color) of $T_2$ plants were compared with those of non-transgenic plants.

Inheritance Types of Wealth and Related Factors among the Elderly Living Independently (단독가구노인의 재산상속의식과 관련요인: 개인특성과 세대관계특성을 중심으로)

  • Kang, Yoo-Jean
    • The Korean Journal of Community Living Science
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    • v.23 no.2
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    • pp.145-162
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    • 2012
  • The purpose of the study was to explore what factors influenced the elderly's prospective inheritance types such as traditional, equal, practical, and non-inheriting type. The role of older parents' socio-demographic and intergenerational characteristics affecting a decision on each pattern was paid special attention to. I used the nationally representative data from 10,469 older parents living independently in the '2008 Korean National Survey of Welfare Need in the Elderly'. Results showed that prospective inheritance types among the elderly were diverse. The type which pursues equal distribution of wealth to all the children emerges predominantly from them. Findings also suggested that inheritance types were associated with factors such as both individual and intergenerational variables. Furthermore, different factors had different impact on each type. Individual variables contributed more to equal types while intergenerational variables contributed to practical types. More interestingly, both individual and intergenerational factors affected non-inheriting types. Further research is necessary to investigate what mechanisms will be operating through the process of inheritance, which social policies will be substituted for the inheritance, and what other variables will account for the intergenerational transmission of wealth.

Linkage Analysis of the Three Loci Determining Rind Color and Stripe Pattern in Watermelon

  • Yang, Hee-Bum;Park, Sung-woo;Park, Younghoon;Lee, Gung Pyo;Kang, Sun-Cheol;Kim, Yong Kwon
    • Horticultural Science & Technology
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    • v.33 no.4
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    • pp.559-565
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    • 2015
  • The rind phenotype of watermelon fruits is an important agronomic characteristic in the watermelon market. Inheritance and linkage analyses were performed for three rind-related traits that together determine the rind phenotype: foreground stripe pattern, rind background color, and depth of rind color. The inheritance of the foreground stripe pattern was analyzed using three different $F_2$ populations, showing that the striped pattern is dominant over the non-striped pattern. The inheritance analysis of the rind background color was performed using $F_2$ populations of the '10909' and '109905', and the depth of rind color was analyzed using $F_2$ populations of the '90509' and '109905'. Yellow color was found to be dominant over green color, and a deep color was dominant over the standard color. Linkage analysis of the three traits was conducted using three $F_2$ populations in which two traits were segregating. Each pair of traits was inherited independently, which demonstrated that the three traits are not linked. Therefore, we propose a three-locus model for the determination of rind phenotype, providing novel insight that rind phenotype is determined by the combination of three genetically independent loci.

A Study on the Genetic Inheritance of Ankyloglossia Based on Pedigree Analysis

  • Han, Soo-Hyung;Kim, Min-Cheol;Choi, Yun-Seok;Lim, Jin-Soo;Han, Ki-Taik
    • Archives of Plastic Surgery
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    • v.39 no.4
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    • pp.329-332
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    • 2012
  • Background Ankyloglossia or tongue-tie is a congenital anomaly characterized by an abnormally short lingual frenum. Its prevalence in the newborn population is approximately 4%. Its mode of inheritance has been studied in some articles, but no conclusion has been established. Also, no relevant report has been published in Korea. This study was conducted to elucidate the genetic inheritance of ankyloglossia via pedigree analysis. Methods In this study, 149 patients with no other congenital anomaly who underwent frenuloplasty between March 2001 and March 2010 were studied. Pedigrees were made via pre- or post-operative history taking, and patients with uncertain histories were excluded. In the patient group that showed a hereditary nature, the male-to-female ratio, inheritance rate, and pattern of inheritance were investigated. Results One hundred (67.11%) of the patients were male and 49 (32.89%) were female (male-female ratio=2.04:1). Ninety-one (61.07%) patients reported no other relative with ankyloglossia, and 58 (38.93%) patients had a relative with this disease. The inheritance rate was 20.69% in the 58 cases with a hereditary nature. In the group with no family history of ankyloglossia, the male-female ratio was 3.79:1, which significantly differed from that of the group with a family history of ankyloglossia. X-chromosome mediated inheritance and variation in the gene expression was revealed in the pedigree drawn for the groups with hereditary ankyloglossia. Conclusions Ankyloglossia has a significant hereditary nature. Our data suggest X-linked inheritance. This study with 149 patients, the first in Korea, showed X-linked inheritance in patients with a sole anomaly.

Frequencies, Inheritance of Porcine FSH-${\beta}$ Retroposon and its Association with Reproductive Traits

  • Li, Feng'e;Xiong, Yuanzhu;Deng, Changyan;Jiang, Siwen;Zheng, Rong
    • Asian-Australasian Journal of Animal Sciences
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    • v.15 no.2
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    • pp.179-183
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    • 2002
  • The fragment in intron I of FSH-${\beta}$ gene was amplified by PCR. According to the polymorphism, we analyzed the distribution of FSH-${\beta}$ retroposon in different pig breeds; its inheritance pattern in Large White${\times}$Meishan reference family; and the association of FSH-${\beta}$ retroposon with litter size, female reproductive organs measurement, ultrasonic backfat and other traits. The results showed that almost each Chinese indigenous pig had the retroposon, while foreign pig breeds rarely had; the frequencies of porcine FSH-${\beta}$ retroposon were strongly associated with breeds (p<0.01); the pattern of inheritance was consistent with Mendelian fashion; total number born (TNB) and number born alive (NBA) were increased per FSH-${\beta}$ retroposon (p<0.01) with additive effects of 1.2-1.8 and 1.4-1.8 pigs/litter, respectively; between the FSH-${\beta}$ retroposon carriers and non-carriers, there was an insignificant difference in the measurement of female reproductive organs, body weight at birth, backfat thickness, loin meat height, lean meat percentage, teat number, days to 100 kg, and average daily gain.

Variability in Specific Leaf Weight in Mulberry Germplasm and Its Inheritance Pattern

  • Sarkar, A.;Mogili, T.;Chaturvedi, H.K.
    • International Journal of Industrial Entomology and Biomaterials
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    • v.7 no.1
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    • pp.69-73
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    • 2003
  • Specific leaf weight (SLW), defined as the mass of tissue per unit leaf area has been found to be an important physiological parameter as it indicates the relative thickness of leaves. Greater SLW provides more photosynthetic potential per unit area of leaf and hence it is frequently been considered as correlated with photosynthesis in several plant species. Collections of 165 mulberry (Morus sp.) germplasm accessions, both Indian and exotic in origin were evaluated for their variability with respect to SLW. The mean specific leaf weight ranged from 35.3 to $72.3 g/m^{-2}$. The distribution of SLW was found to be normal. High heritability (97.08%) and a small difference between genotypic and phenotypic variance demonstrates the genetic control over SLW. Significant heterotic effect with respect to SLW was observed in crosses when parents with high and low SLW were chosen.

Inheritance of Several Qualitative Characters in Cyclamen persicum (시클라멘의 몇 가지 형질의 유전)

  • Song, Cheon Young;Oh, Dae-Geun
    • Korean Journal of Breeding Science
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    • v.42 no.2
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    • pp.188-194
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    • 2010
  • This experiment was conducted to characterize the inheritance of petal color, flower-eye color, flower shape, leaf variegation pattern, and leaf-end shape in Cyclamen persicum. The segregation of $F_2$ and backcross populations from crosses between inbred lines was tested for Mendelian inheritance mode. From four different combinations of crosses, it was found that the petal color was controlled by a single incomplete dominant gene. The other characters, flower-eye color, flower shape, leaf variegation pattern and leaf-end shape were confirmed to be controlled by single complete dominant genes.