• KSBB Journal
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• v.27 no.5
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• pp.295-300
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• 2012

Matured dendritic cells (DCs) begin migration with their release from the bone marrow (BM) into the blood and subsequent traffic into peripheral lymphoid and non-lymphoid tissues. Throughout this long movement, migrating DCs must apply specialized skills to reach their target destination. Non-invasive in vivo cell-tracking techniques are necessary to advance immune cell-based therapies. In this study, we used a DiD cell-tracking solution for in vivo dendritic cell tracking in naive mice. We tracked DiD (non-invasive fluorescence dye)-labeled mature dendritic cells using the Near Infrared (NIR) imaging system in normal mice. We examined the immunophenotype of DiD-labeled cells compared with non-labelled mature DCs, and obtained time-serial images of NIR-DC trafficking after mouse footpad injection. In conclusion, we confirmed that DiD-labeled DCs migrated into the popliteal lymph node 24 h after the footpad injection. Here, these data suggested that the cell tracking system with the stable fluorescence dye DiD was useful as a cell tracking tool to advance dendritic cell-based immunotherapy.

• The Journal of Korean Obstetrics and Gynecology
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• v.29 no.3
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• pp.1-9
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• 2016

Objectives: Cold Hypersensitivity of Hands and Feet (CHHF) has been diagnosed objectively by Digital Infrared Thermal Imaging (DITI) and has been known to be associated with autonomic nervous system (ANS), which can be assessed by Heart Rate Variability (HRV). This study evaluated the correlation between severity of CHHF and HRV variables.Methods: We studied 155 non-menopausal women with CHHF who visited Kyung Hee University Hospital at Gangdong from 01 October 2013 to 30 April 2016. We measured DITI and HRV of each patient. We used DITI to calculate the severity of CHHF with thermal difference between upper arm (L4, 俠白穴) and palm (P8, 勞宮穴) of both hands and anterior thigh (ST32, 伏兎穴) and dorsum of foot (LI3, 太衝穴) of both feet. The correlation between severity of CHHF and HRV variables were analyzed.Results: In time domain analysis, there was significantly positive correlation between the severity of CHHF and both SDNN and RMSSD. In frequency domain analysis, there was significantly positive correlation between the severity of CHHF and TP, HF and HF Norm while there was significantly negative correlation between the severity of CHHF and LF Norm as well as between the severity of cold hypersensitivity of both hands and LF/HF ratio.Conclusions: The more severe CHHF is, the more increased the function of parasympathetic nerve system (PNS) and relatively decreased the function of sympathetic nerve system (SNS) is. Also, it has known that cold hypersensitivity could be caused by deficiency syndrome and qi deficiency has the same ANS tendency as CHHF. Therefore, in practical fields, this result can be helpful in planning treatment and deciding prognosis in respect of deficiency syndrome.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.4 no.4
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• pp.34-38
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• 2005

This is a widespread requirement for low cost lightweight thermal imaging sensors for both military and civilian applications. Today, a large number of uncooled infrared detector developments are under progress due to the availability of silicon technology that enables realization of low cost IR sensor. System prices are continuing to drop, and swelling production volume will soon drive process substantially lower. The feasibility of micromechanical optical and infrared (IR) detection using microcantilevers is demonstrated. Microcantilevers provide a simple Structurefor developing single- and multi-element sensors for visible and infrared radiation that are smaller, more sensitive and lower in cost than quantum or thermal detectors. Microcantilevers coated with a heat absorbing layer undergo bending due to the differential stress originating from the bimetallic effect. This paper reports a micromachined silicon uncooled thermal imager intended for applications in automated process control. This paper presents the design, fabrication, and the behavior of cantilever for thermomechanical sensing.

• Journal of the Korea Safety Management & Science
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• v.23 no.3
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• pp.83-88
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• 2021

Recently, due to the aging of workers and the weakening of the labor base in the automobile industry, research on quality inspection methods through ICT(Information and Communication Technology) convergence is being actively conducted. A lot of research has already been done on the development of an automated system for quality inspection in the manufacturing process using image processing. However, there is a limit to detecting defects occurring in the automotive sunroof sealer application process, which is the subject of this study, only by image processing using a general camera. To solve this problem, this paper proposes a system construction method that collects image information using a infrared thermal imaging camera for the sunroof sealer application process and detects possible product defects based on the SVM(Support Vector Machine) algorithm. The proposed system construction method was actually tested and applied to auto parts makers equipped with the sunroof sealer application process, and as a result, the superiority, reliability, and field applicability of the proposed method were proven.

• Korean Journal of Optics and Photonics
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• v.23 no.1
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• pp.23-31
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• 2012

In this paper, we developed a frequency-domain diffuse optical imaging (DOI) system for imaging non-invasively using near-infrared (NIR) light sources and detectors. 70-MHz modulation and a homodyne scheme were adopted. By calibration of the coupling coefficients, concurrent detection measurements by 4 detector sets were optimized. We presented experimental reconstruction images of absorption and scattering coefficients in a liquid phantom, located an anomaly in the phantom and determined its optical properties. The images by the multi-channel concurrent detection were improved over the results by single-channel sequential detection. Tomographic slices of absorption and scattering coefficients in the phantom with an anomaly were also presented.

• Journal of the Korea Institute of Military Science and Technology
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• v.10 no.3
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• pp.51-61
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• 2007

This paper concerns about the requirement analysis for night vision imaging system(NVIS), whose purpose is to intensify the available nighttime near infrared(IR) radiation sufficiently to be caught by the human eyes on a miniature green phosphor screen. The requirements for NVIS are NVIS radiance(NR), chromaticity, daylight legibility/readability, etc. The NR is a quantitative measure of night vision goggle (NVG) compatibility of a light source as viewed through goggles. The chromaticity is the quality of a color as determined by its purity and dominant wavelength. The daylight legibility/readability is the degree at which words are readable based on appearance and a measure of an instrument's ability to display incremental changes in its output value. In this paper, the requirements of NR, chromaticity, and daylight legibility/readability for Type I and Class B/C NVIS are analyzed. Also the rationale is shown with respect to those requirements.

• Journal of the Semiconductor & Display Technology
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• v.19 no.4
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• pp.1-5
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• 2020

By adapting black body leadflame and thin film type Green A filter, we successfully demonstrated night vision imaging system (NVIS) Green A compatible LED. Fabricated NVIS compatible LEDs show small form factor compared to that of commercialized NVIS compatible LED. Especially, NVIS radiance and chromaticity of MIL-STD-3009 specification can be satisfied simultaneously and easily by controlling the color temperature of the white LED as well as the concentration of the Green A dye and the thickness of the Green A filter. The optimal dye concentration of the NVIS Green A filter is expected to be about 1 wt%. The results of this study are expected to contribute to miniaturization, weight reduction and localization of avionic display and lighting devices.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.21 no.5
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• pp.161-166
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• 2021

When testing various images outdoors with an infrared imaging system, it is necessary to save the tested images for comparison. In addition, after the test, it should be possible to easily connect to the PC and download the stored data. With the recent development of the memory system, it is possible to design an infrared image storage board for an outdoor test by using the eMMC memory that can be easily used in the form of an on board. In this paper, we describe the design of a portable image storage board that can easily store and download infrared images, and describe the GUI program that can connect to a PC and download the stored images.

• Korean Journal of Optics and Photonics
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• v.28 no.5
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• pp.241-249
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• 2017

This paper presents the design and evaluation of the optical system for an uncooled thermal-imaging camera. The operating wavelength range of this system is from $7.7{\mu}m$ to $12.8{\mu}m$. Through optimization, we have obtained a LWIR (Long Wave Infrared) optical system with a focal length of 5.44 mm, which consists of four aspheric surfaces and two diffractive surfaces. The f-number of the optical system is F/1.2, and its field of view is $90^{\circ}{\times}67.5^{\circ}$. The hybrid lens was used to balance the higher-order aberrations, and its diffraction properties were evaluated by scalar diffraction theory. We calculated the polychromatic integrated diffraction efficiency, and the MTF drop generated by background noise. We have evaluated the thermal compensation of a LWIR fixed optical system, which is optically passively athermalized to maintain MTF performance in the focal depth. In conclusion, these design results are useful for an uncooled thermal-imaging camera.

• Publications of The Korean Astronomical Society
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• v.21 no.2
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• pp.43-49
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• 2006

The KASINICS (KASI Near Infrared Camera System) is a ground-based Near-Infrared (NIR) imaging instrument developed by the Korea Astronomy and Space Science Institute (KASI). In this paper, we report the test results of the KASINICS camera optics system which is comprised of a 1-1 Offner relay. We measure that the surface RMS fluctuations of the Offner mirrors are at the level of $10^{-1}-10^{-2}$ of the target wavelengths, showing that the mirrors are sufficiently smooth for NIR observations. The alignment of the Offner optics system has been checked too. Our ray-tracing simulations find that the image quality should not degrade more than the pixel size of the KASINICS ($40{\mu}m$), if a de-centering or a tilt of the Offner mirrors are within 5mm, or $2.5^{\circ}$. Our measurement shows that the de-centering or the tilt of the Offner mirrors are less than 1 mm or $0.5^{\circ}$, assuring that the KASINICS image quality are not affected by the alignment errors. We have also measured that the optics resolution is $20{\mu}m$ and it does not degrade more than 10% over the detector surface area of 14.3 mm ${/times}$ 14.3mm. Overall, we conclude that the KASINICS optics system satisfies the design requirements for NIR imaging observations.