• KSBB Journal
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• 제27권5호
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• pp.295-300
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• 2012

Matured dendritic cells (DCs) begin migration with their release from the bone marrow (BM) into the blood and subsequent traffic into peripheral lymphoid and non-lymphoid tissues. Throughout this long movement, migrating DCs must apply specialized skills to reach their target destination. Non-invasive in vivo cell-tracking techniques are necessary to advance immune cell-based therapies. In this study, we used a DiD cell-tracking solution for in vivo dendritic cell tracking in naive mice. We tracked DiD (non-invasive fluorescence dye)-labeled mature dendritic cells using the Near Infrared (NIR) imaging system in normal mice. We examined the immunophenotype of DiD-labeled cells compared with non-labelled mature DCs, and obtained time-serial images of NIR-DC trafficking after mouse footpad injection. In conclusion, we confirmed that DiD-labeled DCs migrated into the popliteal lymph node 24 h after the footpad injection. Here, these data suggested that the cell tracking system with the stable fluorescence dye DiD was useful as a cell tracking tool to advance dendritic cell-based immunotherapy.

• 한국기계가공학회지
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• 제4권4호
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• pp.34-38
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• 2005

This is a widespread requirement for low cost lightweight thermal imaging sensors for both military and civilian applications. Today, a large number of uncooled infrared detector developments are under progress due to the availability of silicon technology that enables realization of low cost IR sensor. System prices are continuing to drop, and swelling production volume will soon drive process substantially lower. The feasibility of micromechanical optical and infrared (IR) detection using microcantilevers is demonstrated. Microcantilevers provide a simple Structurefor developing single- and multi-element sensors for visible and infrared radiation that are smaller, more sensitive and lower in cost than quantum or thermal detectors. Microcantilevers coated with a heat absorbing layer undergo bending due to the differential stress originating from the bimetallic effect. This paper reports a micromachined silicon uncooled thermal imager intended for applications in automated process control. This paper presents the design, fabrication, and the behavior of cantilever for thermomechanical sensing.

• 대한한방부인과학회지
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• 제29권3호
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• pp.1-9
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• 2016

Objectives: Cold Hypersensitivity of Hands and Feet (CHHF) has been diagnosed objectively by Digital Infrared Thermal Imaging (DITI) and has been known to be associated with autonomic nervous system (ANS), which can be assessed by Heart Rate Variability (HRV). This study evaluated the correlation between severity of CHHF and HRV variables.Methods: We studied 155 non-menopausal women with CHHF who visited Kyung Hee University Hospital at Gangdong from 01 October 2013 to 30 April 2016. We measured DITI and HRV of each patient. We used DITI to calculate the severity of CHHF with thermal difference between upper arm (L4, 俠白穴) and palm (P8, 勞宮穴) of both hands and anterior thigh (ST32, 伏兎穴) and dorsum of foot (LI3, 太衝穴) of both feet. The correlation between severity of CHHF and HRV variables were analyzed.Results: In time domain analysis, there was significantly positive correlation between the severity of CHHF and both SDNN and RMSSD. In frequency domain analysis, there was significantly positive correlation between the severity of CHHF and TP, HF and HF Norm while there was significantly negative correlation between the severity of CHHF and LF Norm as well as between the severity of cold hypersensitivity of both hands and LF/HF ratio.Conclusions: The more severe CHHF is, the more increased the function of parasympathetic nerve system (PNS) and relatively decreased the function of sympathetic nerve system (SNS) is. Also, it has known that cold hypersensitivity could be caused by deficiency syndrome and qi deficiency has the same ANS tendency as CHHF. Therefore, in practical fields, this result can be helpful in planning treatment and deciding prognosis in respect of deficiency syndrome.

• 대한안전경영과학회지
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• 제23권3호
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• pp.83-88
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• 2021

Recently, due to the aging of workers and the weakening of the labor base in the automobile industry, research on quality inspection methods through ICT(Information and Communication Technology) convergence is being actively conducted. A lot of research has already been done on the development of an automated system for quality inspection in the manufacturing process using image processing. However, there is a limit to detecting defects occurring in the automotive sunroof sealer application process, which is the subject of this study, only by image processing using a general camera. To solve this problem, this paper proposes a system construction method that collects image information using a infrared thermal imaging camera for the sunroof sealer application process and detects possible product defects based on the SVM(Support Vector Machine) algorithm. The proposed system construction method was actually tested and applied to auto parts makers equipped with the sunroof sealer application process, and as a result, the superiority, reliability, and field applicability of the proposed method were proven.

• 한국광학회지
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• 제23권1호
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• pp.23-31
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• 2012

본 논문에서는 근적외선(NIR, near-infrared) 영역의 레이저 광원 및 광검출기를 이용한 주파수영역(frequency-domain) 확산 광이미징(DOI, diffuse optical imaging) 시스템을 구현하였다. 검출신호의 진폭 및 위상 추출에는 70MHz의 단일 변조주파수를 사용하는 호모다인(homodyne) 검출기법을 적용하였으며, 4개의 검출기를 이용해 동시측정이 가능하도록 시스템을 최적화하였다. 각 검출기들이 서로 다른 결합계수(coupling coefficient)를 가짐으로써 발생하는 진폭 및 위상의 편차를 보정하였다. 본 논문에서 제작한 DOI 시스템을 이용하여, 생체조직을 모사한 액체팬텀에 이형성분(anomaly)을 삽입하여 흡수 및 산란 분포에 대한 영상을 복원함으로써 이형성분의 위치 및 광학적 특성에 대한 정보를 획득하였으며, 단일 광검출기를 사용하는 순차적인 측정에 의한 결과보다 영상복원 성능이 개선되었음을 보였다. 또한, 동일한 액체팬텀에 대해서, 측정위치를 이동해가며 각 단층 슬라이스에 대한 흡수계수 및 산란계수 분포영상을 복원함으로써 구현된 시스템을 이용해 단층촬영이 가능함을 보였다.

• 한국군사과학기술학회지
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• 제10권3호
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• pp.51-61
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• 2007

This paper concerns about the requirement analysis for night vision imaging system(NVIS), whose purpose is to intensify the available nighttime near infrared(IR) radiation sufficiently to be caught by the human eyes on a miniature green phosphor screen. The requirements for NVIS are NVIS radiance(NR), chromaticity, daylight legibility/readability, etc. The NR is a quantitative measure of night vision goggle (NVG) compatibility of a light source as viewed through goggles. The chromaticity is the quality of a color as determined by its purity and dominant wavelength. The daylight legibility/readability is the degree at which words are readable based on appearance and a measure of an instrument's ability to display incremental changes in its output value. In this paper, the requirements of NR, chromaticity, and daylight legibility/readability for Type I and Class B/C NVIS are analyzed. Also the rationale is shown with respect to those requirements.

• 반도체디스플레이기술학회지
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• 제19권4호
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• pp.1-5
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• 2020

By adapting black body leadflame and thin film type Green A filter, we successfully demonstrated night vision imaging system (NVIS) Green A compatible LED. Fabricated NVIS compatible LEDs show small form factor compared to that of commercialized NVIS compatible LED. Especially, NVIS radiance and chromaticity of MIL-STD-3009 specification can be satisfied simultaneously and easily by controlling the color temperature of the white LED as well as the concentration of the Green A dye and the thickness of the Green A filter. The optimal dye concentration of the NVIS Green A filter is expected to be about 1 wt%. The results of this study are expected to contribute to miniaturization, weight reduction and localization of avionic display and lighting devices.

• 한국인터넷방송통신학회논문지
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• 제21권5호
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• pp.161-166
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• 2021

적외선 영상 시스템으로 야외에서 다양한 영상에 대하여 테스트를 할 때 테스트 한 영상을 저장하여 비교확인이 필요하다. 야외에서 시험을 하기 때문에 휴대성이 간편해야 하며 장시간의 영상을 저장하여야 하기 때문에 많은 저장공간이 필요로 한다. 또한 시험 이후에 쉽게 PC와 접속하여 저장된 데이터를 다운로드 받을 수 있어야 한다. 최근 메모리 시스템의 발전으로 쉽게 On Board 형태로 사용할 수 있는 eMMC 메모리를 활용하여 야외시험용 적외선 영상 저장보드를 설계할 수 있다. 본 논문에서는 적외선 영상을 쉽게 저장하고 다운받을 수 있는 휴대가 간편한 영상 저장보드 설계에 대하여 설명하고 PC와 접속하여 저장된 영상을 다운 받을 수 있는 GUI 프로그램에 대하여 설명한다.

• 한국광학회지
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• 제28권5호
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• pp.241-249
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• 2017

본 논문에서는 $7.7{\mu}m$에서 $12.8{\mu}m$ 파장 대역에 적용 가능한 비냉각 열상장비 광학계를 설계 및 분석 하였다. 최적화 과정을 통하여 설계된 원적외선 광학계의 유효초점거리는 5.44 mm를 가지며, 4면의 비구면과 2면의 회절면을 포함하였다. 광학계의 F/수는 F/1.2로 설정하였고, 시야각은 $90^{\circ}{\times}67.5^{\circ}$가 되도록 하였다. 회절면이 적용된 hybrid 렌즈를 이용하여 보다 효율적으로 고차 수차가 보정되도록 하였고, 이때 발생되는 회절 특성은 scalar 회절 효율을 이용하여 평가하였다. 또한 hybrid 렌즈에서 발생되는 회절 현상에 의한 통합 회절효율을 예측하고 배경잡음에 의한 MTF 저하를 고려하였다. 원적외선 광학계의 온도 변화에 따른 보상은 광학식 비열화를 이용하여 광학계의 MTF 성능이 초점 심도 내에서 유지되도록 하였다. 결론적으로 비냉각 열상장비에 효율적으로 적용 가능한 광학설계 결과를 얻었다.

• 천문학논총
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• 제21권2호
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• pp.43-49
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• 2006

The KASINICS (KASI Near Infrared Camera System) is a ground-based Near-Infrared (NIR) imaging instrument developed by the Korea Astronomy and Space Science Institute (KASI). In this paper, we report the test results of the KASINICS camera optics system which is comprised of a 1-1 Offner relay. We measure that the surface RMS fluctuations of the Offner mirrors are at the level of $10^{-1}-10^{-2}$ of the target wavelengths, showing that the mirrors are sufficiently smooth for NIR observations. The alignment of the Offner optics system has been checked too. Our ray-tracing simulations find that the image quality should not degrade more than the pixel size of the KASINICS ($40{\mu}m$), if a de-centering or a tilt of the Offner mirrors are within 5mm, or $2.5^{\circ}$. Our measurement shows that the de-centering or the tilt of the Offner mirrors are less than 1 mm or $0.5^{\circ}$, assuring that the KASINICS image quality are not affected by the alignment errors. We have also measured that the optics resolution is $20{\mu}m$ and it does not degrade more than 10% over the detector surface area of 14.3 mm ${/times}$ 14.3mm. Overall, we conclude that the KASINICS optics system satisfies the design requirements for NIR imaging observations.