• BMB Reports
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• v.55 no.10
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• pp.500-505
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• 2022

Uncoupling protein 2 (Ucp2) was first introduced as a member of Uncoupling protein family and a regulator of ROS formation; however, its role in adipose tissue is not fully understood. In the present study, we have investigated the role of Ucp2 against high-fat diet (HFD)-induced obesity in epididymal white adipose tissue (eWAT) and browning of inguinal white adipose tissue (iWAT). Diet-induced obesity is closely related to macrophage infiltration and the secretion of pro-inflammatory cytokines. Macrophages surround adipocytes and form a crown-like-structure (CLS). Some reports have suggested that CLS formation requires adipocyte apoptosis. After 12 weeks of HFD challenge, Ucp2 knockout (KO) mice maintained relatively lean phenotypes compared to wild-type (WT) mice. In eWAT, macrophage infiltration, CLS formation, and inflammatory cytokines were reduced in HFD KO mice compared to HFD WT mice. Surprisingly, we found that apoptotic signals were also reduced in the Ucp2 KO mice. Our study suggests that Ucp2 deficiency may prevent diet-induced obesity by regulating adipocyte apoptosis. However, Ucp2 deficiency did not affect the browning capacity of iWAT.

• IMMUNE NETWORK
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• v.19 no.1
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• pp.3.1-3.17
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• 2019

Aging is a complex process associated with dysregulation of the immune system and low levels of inflammation, often associated with the onset of many pathologies. The lacrimal gland (LG) plays a vital role in the maintenance of ocular physiology and changes related to aging directly affect eye diseases. The dysregulation of the immune system in aging leads to quantitative and qualitative changes in antibodies and cytokines. While there is a gradual decline of the immune system, there is an increase in autoimmunity, with a reciprocal pathway between low levels of inflammation and aging mechanisms. Elderly C57BL/6J mice spontaneously show LGs infiltration that is characterized by Th1 but not Th17 cells. The aging of the LG is related to functional alterations, reduced innervation and decreased secretory activities. Lymphocytic infiltration, destruction, and atrophy of glandular parenchyma, ductal dilatation, and secretion of inflammatory mediators modify the volume and composition of tears. Oxidative stress, the capacity to metabolize and eliminate toxic substances decreased in aging, is also associated with the reduction of LG functionality and the pathogenesis of autoimmune diseases. Although further studies are required for a better understanding of autoimmunity and aging of the LG, we described anatomic and immunology aspects that have been described so far.

• Proceedings of the Korean Radioactive Waste Society Conference
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• 2005.06a
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• pp.211-220
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• 2005

The concrete structure is being considered for the main engineered barrier of low and intermediate level radwaste disposal facility. Concrete of low permeability can minimize infiltration of water and effectively prevent release of nuclide to ecosystem. But if concrete degrades, structural stability of disposal structure will decrease while permeability increase, resulting in increased possibility of nuclide release due to water infiltration. Therefore disposal concrete structure degradation shall be minimized to maintain capacity of nuclide isolation. The typical causes of concrete structure degradation are sulfide attack, reinforcement corrosion due to chloride attack, leaching of calcium hydroxide, alkali-aggregate reaction and repeated freezing-thawing. The common cause of these degradation processes is infiltration of water or adverse chemicals into concrete. Based on the study of these degradation characteristics and mechanisms of concrete structure, the methodology of design and service life evaluation of concrete structure as an engineered barrier are reviewed to ensure its long-term durability.

• Journal of the Korean Institute of Landscape Architecture
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• v.26 no.2
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• pp.54-61
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• 1998

The subsurface environment of the root zone area can set the stae for "do or die" of the turfgrass plant. The good condition of the greens is verified by their physical properties. Therefore, this study was carried to evaluate on the existing green of Hwasan C.C. by undisturbed soil Core Anaysis. We completed the ISTRC SYSTEM BenchMarking of the undisturbed core samples taken from Green #1, Green #5, Green #9-"Best" area, and Green #9-"Stressed" area for the Hwasan C.C.. It was also our understanding that the greens were in "good" to "very good" conditioni. THe exception might be Green #9-"Stress" area, which was the stressed area. The stressed area was confined to a ridge across Green #9. The organic content test results comfirmed the development of organic layering in depth 0-2.5cm. For the amount of compaction in the upper root zones and te development of the green's respective organic layers, the infiltration rates were high in Green #1, Green #5, and Green #9 "Stressed" area. The depicted aerificaton hole might be the probable cause of the relatively high infiltraton rate. Green #9-"Best" area had a tested infiltration rate of 18.75cm/hr. Either this area had not been aerified, or the undisturbed sample did not contain a aerification cavity. The water retention capacity of the undisturbed samples was good. When the greens were first constructed, the original root zone mix had been relatively low water retention properties. And the bulk density and the porosity of the undisturbed samples were good. In the result, all the greens were similar except for the infiltration. Thus, we supposed that Green #9-"Stressed" area might be ainly influenced by the amount of irrigation water and the configuration of the green's surface. There had been a reduction in the amount of irrigation water as the water retention capacity in the greens was promoted. Especially, it had gradually become more of a problem as the green had matured in Green #9-"Stressed" area. Because Green #9-"Stressed" area was a ridge area. The reduction in the amount of irrigation water might be the probable cause of the stress in Green #9-"Stressed" area. Our final observation related to the soil texture and the particle size distribution of the sand. Though and sand contant of all the tested greens were good, the gravel content of them exceeded ISTRC Guidelines. In particle size distribution of the sand, the very coarse and the coarse content of all the tested greens exceeded, but the rest was insufficient. The stability is a function of the material retained on the 0.25mm mesh screen. But, the content of all the tested greens was very insufficient. Though all the greens was serviceable, the coarse root zone sands, such as the sand in the tested greens, tended to be "unstable". Thus, we recommend using a topdressing/aerification sand which should be more in line with ISTRC/USGA Guidelines.;unstable". Thus, we recommend using a topdressing/aerification sand which should be more in line with ISTRC/USGA Guidelines.ines.

• Journal of Korean Society of Environmental Engineers
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• v.31 no.1
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• pp.70-78
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• 2009

Floodplain areas of major South Korean rivers were determined by analyzing topographical maps and hydraulic properties of floodplain soil were measured using disc tension infiltrometer. To assess the possibility of treating secondary effluents of municipal wastewater with floodplain soil, a computer code for the analysis of unsaturated flow in soil was employed along with searches conducted in the literature. Based on the data generated, an estimate of total floodplain filtration capacity in Korea was obtained. The results of our study reveal that Korean floodplains have surface soil that is adequate for treating water. Moreover, the distributions of floodplains are substantial over the entire reaches of the rivers, indicating that the conditions are favorable for floodplain filtration as additional treatment of secondary effluent. The capacity of floodplain filtration in Korea is circa 182,000,000 $m^3$/day and most of the rivers are estimated to have enough capacity of floodplain filtration to meet all the secondary effluent, indicating that this technology may be expected to make further improvements on river water quality. Furthermore, this method may also be applied to better the source-water quality for drinking water.

• Journal of Korean Society on Water Environment
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• v.23 no.4
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• pp.490-497
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• 2007

A Combined sewer overflows (CSOs) are themselves a significant source of water pollution. Therefore, the control of urban drainage for CSOs reduction and receiving water quality protection is needed. Examples in combined sewer systems include downstream storage facilities that detain runoff during periods of high flow and allow the detained water to be conveyed by an interceptor sewer to a centralized treatment plant during periods of low flow. The design of such facilities as stormwater detention storage is highly dependant on the temporal variability of storage capacity available (which is influenced by the duration of interevent dry periods) as well as the infiltration capacity of soil and recovery of depression storage. As a result, a continuous approach is required to adequately size such facilities. This study for the continuous long-term analysis of urban drainage system used analytical probabilistic model based on derived probability distribution theory. As an alternative to the modeling of urban drainage system for planning or screening level analysis of runoff control alternatives, this model have evolved that offer much ease and flexibility in terms of computation while considering long-term meteorology. This study presented rainfall and runoff characteristics of the subject area using analytical probabilistic model. This study presented the average annual COSs and number of COSs when the interceptor capacity is in the range $3{\times}DWF$ (dry weather flow). Also, calculated the average annual mass of pollutant lost in CSOs using Event Mean Concentration. Finally, this study presented a decision of storage volume for CSOs reduction and water quality protection.

• Proceedings of the Korea Water Resources Association Conference
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• 2022.05a
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• pp.147-147
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• 2022

In January 2021 heavy flood affected South Kalimantan with causing many casualties. The heavy rainfall is predicted to be generated due to the ENSO (El Nino-Southern Oscillation). The weak La-Nina mode appeared to generate more convective cloud above the warmed ocean and result in extreme rainfall with high anomaly compared to past historical rainfall event. Subsequently, the antecedent soil moisture distribution showed to have an important role in generating the flood response. Saturated flow and infiltration excess mainly contributed to the runoff generation due to the high moisture capacity. The hydro-meteorological processes in this event were deeply analyzed using the coupled atmospheric model of Weather Research and Forecasting (WRF) and the hydrological model extension (WRF-Hydro). The sensitivity analysis of the flood response to the SST anomaly and the soil moisture capacity also compared. Result showed that although SST and soil moisture are the main contributors, soil moisture have more significant contribution to the runoff generation despite of anomaly rainfall occurred. Model performance was validated using the Global Precipitation Measurement (GPM) and Soil Moisture Operational Products System (SMOPS) and performed reasonably well. The model was able to capture the hydro-meteorological process of atmosphere and hydrological feedbacks in the extreme weather event.

• Proceedings of the Korean Society of Soil and Groundwater Environment Conference
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• 2002.04a
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• pp.179-182
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• 2002

The objective of this study was to evaluate petroleum hydrocarbon degradation processes governing natural attenuation at tile contaminated site and accomplished through conducting on investigation of degradation rate, capacity, and mechanism of the monitored natural attenuation. The monitoring results of the three years indicated that the concentrations of DO, nitrate, and sulfate in the contaminated area were significantly lower than these in the none-contaminated area. The results also showed a higher ferrous iron concentration, a lower redox potential and a neutral pH in the contaminated groundwater, suggesting that biodegradation of TEX is the major on-going process in the contaminated area. However, reduction of TEX in the groundwater was not only biodegradation but also dilution and reaeration during infiltration of uncotaminated surface and groudwater.

• Journal of the Korean Professional Engineers Association
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• v.43 no.6
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• pp.31-34
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• 2010

Recently, due to localized heavy rain and flash floods in urban areas is becoming more frequent flood damage. To prevent flood inundation damage, to formulate the diverse directions in connection with the drainage system of buildings, roads, sewerage, pump stations, detention (retention) pond, and streams is very important. In addition, it is important for the uniform design criteria, the consistent of hydrologic and hydraulic analysis method, and a flood disaster mitigation systems connected with structural and nonstructural measures. To accomplish this, the method such as installation of storage facilities, infiltration facilities, and underground water tank, the optimal size of the design gutter and grate of the road, ensure the capacity of pumping stations, and the installation of a flood control channel into the deep underground requires comprehensive measures dimension in urban areas.

• Proceedings of the Korean Society of Agricultural Engineers Conference
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• 2001.10a
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• pp.45-50
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• 2001

The purpose of this study was to estimate of soil loss form hillslope using WEPP(Water Erosion Prediction Project) model. WEPP model was developed for predicting soil erosion and deposition, fundamentally based on soil erosion prediction technology. The model for predicting sediment yields from single storms was applied to a tested watershed. Surface runoff is calculated by kinematic wave equation and infiltration is based on the Green and Ampt equation. Governing equations for sediment continuity, detachment, deposition, shear stress in rills, and transport capacity are presented. Tested watershed has an area of 0.6ha, where the runoff and sediment data were collected. The relative error between predicted and measured runoff was $-16.6{\sim}2.2%$, peak runoff was $-15.6{\sim}2.2%$ and soil loss was $-23.9{\sim}356.5%$.