• The Journal of Korean Obstetrics and Gynecology
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• v.30 no.3
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• pp.128-135
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• 2017

Objectives: This study is to report the effects of acupuncture, moxibustion and herbal medicine on infertility. Methods: From February 2015 to December 2016, 44 women with infertility were treated with acupuncture, moxibustion and herbal medicine. 6 months later, follow up and analysis were performed. Results: Of the total 44 women, 19 were successful in pregnancy. Of the 30 women who were contacted by follow-up after 6 months, 19 (63.3%) were successful in pregnancy. 6 of the 8 women who had abortion experience and 5 of the 6 women without the symptoms were pregnant. And 2 with dysmenorrhea, women with follicular development failure, hydrosalpinx, ectopic pregnancy, anovulatory infertility patients, polycystic ovary syndrome were all successfully pregnant. Conclusions: This study suggests that acupuncture, moxibustion and herbal medicine are useful and shows possibility to increasing pregnancy rates.

• Proceedings of the Korean Operations and Management Science Society Conference
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• 1987.10a
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• pp.3-3
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• 1987

현재 국내에서의 의료 부분의 전문가 시스템에 대한 개발이 시작 단계에 있다. 의료부문 전문가시스템 개발에 있어서 주요 촛점은 관련분야의 전문의들로부터 어떻게 시간적, 비용적 낭비없이 효과적으로 지식 획득(Knowledge acquisition)을 knowledge engineers가 하겠는가이며, 또한 어떠한 체계(Framework)로 전문가 시스템을 구성할 것인가이다. 본 발표에서는 현재 본 연구실에서 CASNET 및 INTERNET를 바탕으로 개발중인 산부인과의 불임 진료 및 내과의 갑상선 질환 진단, 치료에 관련된 전문가 시스템 개발의 초기단계를 보임으로써 의료 관련 전문가 시스템 개발의 일반적인 기본 방향을 제시하고자 한다.

• Clinical and Experimental Reproductive Medicine
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• v.4 no.2
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• pp.35-43
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• 1977

A total of 636 patients of primary infertility were analyzed by computer on the basis of statistical evaluation of etiological factors and therapy with the outcome of the pregnancy. In this report, it included the results of the study analyzed the single etioligic factors responsible for the primary infertility with the outcome of the pregnancy. 1. Two hundred and fourty one patients out of a total 636(37.9%) achieved pregnancy. 2. Four hundred and fifty nine patients out of a total 636(72%) had a single etuiologic factor responsible for the primary infertility. 3. One hundred and seventy six patients out of 459 parients (38.3%) who had a single etiologic factor responsible for the primary infertility achieved a pregnancy. 4. The endometriosis was the most frequent responsible factor for the primary infertility. 5. The success rate of the pregnancy was different in each etioligic factor responsible for the primary infertility. The highest success rate of the pregnancy was in the patients who had the intermediate factor responsible for the primary infertility as much as 66.7% of the patients. 6. The expectancy of the pregnancy in terms of the duration of the therapy and the follow-up was variable and depended upon the etiologic factor of the primary infertility.

• Journal of Korean Academy of Nursing
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• v.29 no.6
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• pp.1379-1391
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• 1999

The purpose of this study was to investigate loneliness in infertile women and determine how loneliness related to personal characteristics, cause of infertility, family composition, and family conflicts. It also provides basic data for nursing strategies concerning infertile women.A total of 182 subjects were selected at an infertile clinic in Seoul, Korea. Data were collected from May 2 to June 21, 1997 by questionaire. It consisted of questions concerning general characteristics, items relating to infertility, and the Loneliness Scale. The UCLA Loneliness scale was used(more specifically, the Korean version of the Revised UCLA Scale by Kim Ok Soo.) The data were analyzed by using SPSS/PC computer program. The result are as follows : 1. The mean age of infertile women was 32.4 years old, and the mean age of souses was 34.8 yerars old. 30.2% of women had a marital duration of 3-5 years, and 25.8% had a marital duration of 5-10 years. 23.1% reported the main etiology of infertility as unexplained, 18.1% reported ovulation disturbances, and 26.4% reported complex causes. 3.8% of the couples had sexual relationship difficulty 83% lived in nuclear families, while 17% lived in large families. 2. The mean loneliness scores of infertile women was 35.53(SD=8.66). The total loneliness score of this study was 80. 3. There were significant differences in loneliness scores according to ages(F=6.893, p=.001), education background(t=4.418, p=.000), and the educational background of husband(t=2.339, p=.020). 4. Loneliness scores related to family situations were significantly different according to several male nephews in husbands' family(F=2.822, p=.027). 5. Loneliness scores related to conflicts were significantly different according to husbands and their family(F=11.465, p=.000). Nurses should acknowlege the fact that some infertile women may experience loneliness. In conclusion, nurses can provide infertile women with information about ways to decrease loneliness and create support groups for themselves, assisting infertile women to adjust to the experience of infertility through positive methods.

• Clinical and Experimental Reproductive Medicine
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• v.33 no.4
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• pp.219-227
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• 2006

Objective: To evaluate the impact of endometriosis on IVF-ET cycles and to compare IVF outcomes between stage I/II and stage III/IV endometriosis. Methods: We analyzed 697 patients (1,199 cycles) with endometriosis (stage I-II:638 cycles, stage III-IV: 561 cycles) and 325 pts (459 cycles) with tubal factor as controls between January 1994 and April 2004. Pts with endometriosis were diagnosed by laparoscopy and medical and surgical treatment were done in 353 cycles (55.3%) and 466 cycles (83.1%) of stage I-ll/stage III-IV endometriosis. Cycles with age>35 years or FSH>20 miU/mL or severe male factor infertility were excluded. Results: The number of retrieved oocytes ($9.97{\pm}7.2$ vs. $13.4{\pm}7.9$ (p<0.0001 )), total number of embryos ($6.5{\pm}4.8$ vs. $9.1{\pm}5.6$ (p<0.0001)), and good quality embryos ($2.43{\pm}1.6$ vs. $2.74{\pm}1.7$ (p=0.013)) significantly decreased in stage III-IV endometriosis than in control. But pregnancy rate of stage III-IV endometriosis was comparable with control (35.7% vs. 36.8%). Fertilization rate and number of total embryos were lower in stage I-II endometriosis than in control ($64.8{\pm}22.9$ vs. $70.8{\pm}20.8$ (p<0.0001), $7.6{\pm}5.0$ vs. $9.1{\pm}5.6$ (p<0.0001)). In patients with medical and surgical treatment of endometriosis, pregnancy rate and live birth rate was significantly lower in stage I-II than in stage III-IV endometriosis (29.2 vs. 36.2 (%), p=0.045, 23.9 vs. 31.5 (%), p=0.043). There was no difference in the mean age, but the duration of infertility was significantly longer ($56.5{\pm}26.3$ vs. $46.9{\pm}25.8$ (mon), p<0.0001) and fertilization rate was lower ($64.7{\pm}23.3$ vs. $70.5{\pm}22.7$ (%), p=0.001) in stage I-II than stage III-IV endometriosis. Conclusion: We suggest that IVF should be considered earlier in patients with minimal to mild endometriosis because of significantly decreased fertilization rates.

• Journal of Oriental Medical Thermology
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• v.2 no.1
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• pp.35-42
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• 2003

Objective : This study is to examine the interrelationship between Infertility with hypothalamic-pituitary gland disorders and Face temperature by D.I.T.I. Methods : Sample group is the 50 women who were diagnosed as P.C.O.S. or FSH,LH trouble or hyper-prolactinemia or anovulation or oligo-ovulation. Control group is the 50 women who have not P.C.O.S. & FSH.LH trouble & hyper-prolactinemia & anovulation or oligo-ovulation, who have normal menstural cycle and success in pregnancy after treatment. Both group came at Conmaul Oriental Hospital Infertility Center, Seoul, Korea, from May, 2001 to Jan., 2003. They selected at random. We checked temperature of ${\ulcorner}S17{\lrcorner}\;{\ulcorner}SI18{\lrcorner}\;{\ulcorner}TE17{\lrcorner}\;{\ulcorner}HN-3{\lrcorner}$ and gained differences of Rt. check point and Lt. check point, and then compared mean ${\Delta}T$ of sample group with that of control group. Conclusion : We gained results that mean ${\Delta}T$ of sample group is larger than that of control group at all check points. (p=0.000)

• Journal of the korean veterinary medical association
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• v.14 no.3
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• pp.153-156
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• 1978

Therapeutic effects of synthetic PGF 2 alpha (Estrumate, ICI) were evaluated in various cases of bovine infertility. of 19 anestrus dairy cows (Holstein-Friesian) for 3 to 12 months post-partum, 16 showed estrus within 10 days after a single intramuscular

• Clinical and Experimental Reproductive Medicine
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• v.12 no.1
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• pp.47-70
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• 1985

This study was presented of the 1,872 cases of infertile couples who visited and examined at the sterility clinic of Department of Obstetrics & Gynecology, Seoul National University Hospital from Sept., 1980 to Dec., 1983. Age, duration of infertility, past medical history, and other general factors were analyzed, and the factors responsible for infertility were classified and discussed. Mode of treatment, outcome of pregnancy, pregnancy rate responsible for each factor were also presented. The results were as follows: 1) The infertility was primary in 1,128, or 60.3% and secondary in 744, or 39.7%. 2) The age between 26 and 30 years of age comprised about one half of the total patients. 3) The duration of infertility between 1 and 4 years comprised about three quarters of the total patients, and the mean duration was 3.8 years. 4) The most common medical history in primary infertility was tuberculous disease, and that in secondary infertility was history of previous laparotomy. 5) About two thirds of antecedent pregnancies were abortion. 6) The major etiologic factor of infertility were male factor in 12.3%, tubal factor in 38.8%, ovulatory failure in 25.4%, uterine factor in 8.8%, cervical factor in 5.2%, peritoneal factor in 9.5%, and no demonstrable cause in 11.3%. 7) The types of male factor were azoospermia in 61.6%, oligospermia in 25.8%, low motility in 11.6%, and other abnormality in 1.0%. 8) The types of ovulatory failure were ovarian failure in 7.4%, hypothalamo-pituitary failure in 8.1 %, hypothalamo-pituitary dysfunction (including Polycystic ovarian syndrome) in 30.2%, and hyperprolactinemia in 22.4%. 9) The types of uterine factor were endometrial tuberculosis in 27.5%, uterine synechia in 33.8%, uterine anomaly in 19.7%, myoma and polyp in 9.1 %, and luteal phase defect in 9.9%. 10) The types of peritoneal factor were pelvic adhesion in 80.9% and endometriosis in 19.6%. 11) Surgeries were done in 408 patients, and they were salpingolysis, lysis of extraadnexal adhesion, salpingostomy, fimbrioplasty, ovarian wedge resection for polycystic ovarian disease, tubo-tubal anastomosis, and tubo-uterine implantation in orders. 12) 243 pregnancies were achieved during the infertility work-up, of which livebirth was 46.5%, ectopic pregnancy was 7.4%, spontaneous abortion was 7.8%, and on-going pregnancy or lost to follow-up was 36.2%. 13) Pregnancy rates in various factors were male factor in 18.7%, ovulatory factor in 31.7%, tubal factor in 24.2%, uterine factor in 34.6%, cervical factor in 19.0%, peritoneal factor in 29.0%, combined factors in 10.5%, and unexplained infertility in 37.1%. Pregnancy rate in whole patients was 25.2%.

• Journal of Physiology & Pathology in Korean Medicine
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• v.28 no.3
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• pp.355-358
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• 2014

It is not yet clear that treatment for infertility with uterine myoma or adenomyosis. And myomectomy has the risk of side effects and reducing pregnancy rate. Therefore myoma or adenomyosis who want to be pregnant is ecessary. In this study, the patient who had uterine myoma and adenomyosis was treated by Oriental medical treatments such as herbal medicine and acupuncture. After treatment, the patient's menstrual condition was improved and became pregnance. This case report shows that the Oriental medical treatment is effective for infertility patients with uterine myoma or adenomyosis.

• 대한상한금궤의학회지
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• v.6 no.1
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• pp.37-54
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• 2014

Objective : The purpose of this paper is to report the effect of three different herb medication based on Shanghanlun(傷寒論) six differential diagnostic system. Methods : According to six differential diagnostic system based on Shanghanlun provisions, they were diagnosed with Taiyang-byung(大陽病), Yangmyung-byung(陽明病), Gwoleum-byung(厥陰病). They took different herb medications more than 6weeks according to their diagnosis. This paper evaluated the results of treatment by pregnancy test result with improvement of symptoms. Results : The symptoms of three patients were improved and became pregnant. Conclusions : This case study suggests that herb medication based on Shanghanlun(傷寒論) six differential diagnostic system have effectiveness on unexplained infertility. And we need to have a diversified and new perspectives in women's position about pregnancy with this system.