• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.17 no.2
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• pp.104-111
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• 2014

Purpose: To evaluate safety, gastrointestinal tolerance, and growth of a new experimental starter formula (NESF) fortified with lutein, prebiotics, probiotics, nucleotides and beta-carotene, fed to infants within the first months of life. Methods: This was a non-randomized, open, uncontrolled study conducted from December 2010 to May 2011. Twenty-three healthy infants aged 10 days to 2 months old were enrolled. Outcomes included gastrointestinal tolerance, physical growth and safety. Prior to the initiation of the trial, the Scientific Research Institute of Nutrition of the Russian Academy of Medical Sciences confirmed that the NESF met all safety and nutritional parameters. Results: NESF was well tolerated. The majority of infants fed this formula passed semi-liquid, yellow or yellow-brown. The mean stool frequency/day was $2.5{\pm}0.4$ on study-day 14 and $1.8{\pm}0.5$ on study-day 28. The mean daily weight gain was $30.9{\pm}3.8$ grams and the mean length gain during the 28 days of follow up was $3.1{\pm}0.8cm$, corresponding to the average physical growth normally seen in the first months of life in Russian infants. Six children left the study: one refused to drink the formula, one left the study as parents changed residence; and one child's parents have recalled their informed consent due to adverse event unrelated to the product. Three infants presented adverse events possibly related to the product (rash; colic and abdominal pain; constipation). Seventeen infants completed the trial. Conclusion: This study demonstrated that lutein-fortified formula is safe, well-tolerated and supported physical growth of evaluated infants.

• Child Health Nursing Research
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• v.10 no.1
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• pp.5-13
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• 2004

Purpose: The aim of this study was to analyze the correlation of gestational age and birth weight with weight gain of very low birth weight infants(VLBWI) during their hospital stay. Method: This is a 5 year retrospective study of which data were collected through review of medical records. Subjects were 124 VLBW infants with a birth weight more than 1000g and less than 1500g who received neonatal intensive care at the university hospital between January 1, 1997 to December 31, 2001. Result: After calculating the z scores of birth weights and discharge weights, z scores of discharge weight and birth weight were compared with the median weight of a fetus of comparable gestational age based on an intrauterine growth reference. There was a significant difference between z scores of birth weight and discharge weight(t=11.60, df=122, p=0.000). Regardless of intensive care during the prolonged hospital stay, VLBW infants showed slow growth rate compared with the median weight of a fetus of comparable gestational age. Conclusion: VLBW infants developed a poor velocity of weight gain during the prolonged hospital stay after birth. The development worsened during the period of physiological weight loss and regain, and they did not reach to comparable growth rate of normal fetus even at the time of discharge. This poor growth velocity of VLBW infants influence negatively for their future growth. Therefore nureses who work at the neonatal intensive care unit must develop an effective nursing intervention protocol to promote the velocity of weight gain and to conduct the parental educational sessions to emphasize the importance of weight gain for VLBW infants at home.

• Korean System Dynamics Review
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• v.11 no.3
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• pp.5-31
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• 2010

The purpose of this study is to develop a system dynamics model for growth prediction of low birth weight infants(LBWIs) based on nutrition. This growth prediction model consists of 9 modules; body weight, height, carbohydrate, protein, lipid, micronutrient, water, activity and energy module. The results of the model simulation match well with the percentiles of weights and heights of the Korean infants, also with the growth records of 55 LBWIs, under 37 weeks of gestational age, whose weights are appropriate for their gestational age. This model can be used to understand the current growth mode of LBWIs, predict the future growth of LBWIs, and be utilized as a tool for controlling the nutrient intake for the optimal growth of LBWIs in actual practice.

• Nutrition Research and Practice
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• v.5 no.4
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• pp.308-312
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• 2011

This was a prospective cohort study of 976 infants from birth to 12 months of age. Infants were fed breast milk, goat infant formula, cow infant formula, or a combination of formula and breast milk during the first 4 months of age. Data on type of milk feeding and infant growth (weight and height) were collected at birth and at 4, 8, and 12 months during routine clinical assessment. The number and consistency of bowel motions per day were recorded based on observational data supplied by the mothers. Infants fed breast milk or goat or cow infant formula during the first 4 months displayed similar growth outcomes. More of the infants fed cow infant formula had fewer and more well-formed bowel motions compared with breast-fed infants. The stool characteristics of infants fed goat formula resembled those of infants fed breast milk.

• Clinical and Experimental Pediatrics
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• v.55 no.8
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• pp.272-279
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• 2012

Purpose: The aim of this study was to develop an appropriate nursing information guideline according to corrected age, after investigating parents' concerns about the growth, development, and diseases of their premature infants after discharge from the neonatal intensive care unit (NICU). Methods: The parents of premature infants (birth weight, <2,500 g; gestational age, <37 weeks) who went to a neonatal follow-up clinic after NICU discharge at Seoul St. Mary's Hospital from January 2005 to December 2009, were asked with regard to their concerns about their infants through a questionnaire survey. The results of physical examinations, including body measurements and neurodevelopmental status at 4, 8, 12, and 18 months of corrected age, were retrospectively reviewed in 390 infants. Results: The most common parental concerns were developmental delay, poor growth, and feeding and nutritional problems. Parental concerns about developmental delay, growth failure in improvement in body weight and length, and overweightness were high in specificity but very low in sensitivity. After NICU discharge, 30% of premature infants experienced infectious diseases before 18 months of corrected age, the most common of which was respiratory tract infection. Conclusion: For guiding of premature infants in outpatient day clinics after NICU discharge, it is necessary to identify the parents' highest concerns, to educate them about the possibilities of growth and neurodevelopmental disabilities in their infants and to provide them with handouts containing guidelines on the management of infectious diseases, especially respiratory infections.

• Journal of Nutrition and Health
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• v.30 no.3
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• pp.336-348
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• 1997

The objectives of this study were to examine the growth pattern of infants by anthropometric measurement according to the 5 feeding practices of infants with the subject of two hundred healthy newborn babies from their birth till sixty month of age at intervals of two months. Breast group(BF, n=38), formula group(FF, n=102) and mixed group(ME, n=14) were fed breast milk, formula milk, breast and formula milk, from birth till 6 mo. of age, respectively. Convert 1 group (C1F, n=14) and covert 2 group(CF, n=32) were fed breast milk and mixed milk at 2 mo. of age afterthat switched to formula milk, respectively. From these, the following results were made. All the infants of this study showed superiority to Korean standard growth rate in regards to each growth item for each month age. In the case of males, at their birth, the subscapular skinfold thickness and the total skin fold thickness in the BF group was significantly larger than in MF group and FF group(p<0.05). At 6th month age, the chese circumference of MF group was 45.9cm, and significantly larger than those of BF, FF and C2F groups(p<0.05). In the case of females, at theri birth and 2nd month age, there was no difference among all the feeding groups in regards to each growth rate. At 4th month age, the Kauf index of C1F group was 16.21 and significantly lower than those of four groups(p<0.05). And total skinfold thickness in BF group was larger than in C1F group. The increase rate per month age of all growth items were larger at 2nd month age than at the later months both in males and in females. And until 2nd month age males showed more increase than females in regards to each growth item but after 2nd month age, this sapect did not show up. Multiple linear regression was used to determine predictive factors for infant growth. It was expected that at 6th month age, in the measurement of head circumference and chest circumference and cross-sectional fat area, BF-males were bigger by 22-39% of the explanation index than the infants of other groups. As a result, in spite of the significant lower intakes of energy and nutrients in breast-fed infants than in formula-fed infants, breast-fed infants showed more growth than the average of Korean infant standard growth rate at every month age, and showed no significant growth difference among feeding groups.

• Child Health Nursing Research
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• v.15 no.4
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• pp.335-342
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• 2009

Purpose: This study, using a pre-post test design of non-equivalence comparative group, was done to determine effects of Kangaroo care (KC) on growth in premature infants and on maternal attachment (MA). Methods: Fifty-three premature infants were assigned to the KC (24) or control group (CG) (29). Data were collected from July 2007 to June 2008. KC was given for 60 min at a time, Monday, Wednesday, and Friday for 10 times. Weight, height, and head circumference (HC) of premature infants were checked before the program started. Following the initial measurement, the program was given and measurements were taken again at the end of the program. For measurement of attachment between mother and infant, data collection was done using structured self-reported questionnaires. Results: KC group had a higher weight (t=2.565, p=.013), height (t=2.182, p=.034) and HC (t=2.468, p=.017) than the CG. Compared to the CG, the KC had significantly higher scores in MA (t=2.026, p=.048). Conclusion: The results of this study suggest that the practice of KC in the nursing environment might actively promote attachment between mother and infant as well as acceleration of growth for premature infants as one of the most efficient nursing intervention.

• Child Health Nursing Research
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• v.14 no.3
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• pp.252-260
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• 2008

Purpose: This study was done to investigate effect of Meridian massage on the infant' growth and parenting stress, parenting self-efficacy in their mothers. Method: The participants were 65 mothers of infants who visited one public health center in Yangju city. Data were collected from February, 2007 to December, 2007. Infant in the experimental group were given Meridian massage for 50min(lecture 20min, practice 15min, preparation and arrangement 15min) once a week for 6 weeks. The data were analyzed using the SPSS program. Result: Regarding growth, infants in the experimental group increase in height compared to those in the control group. There was no difference in infants weight between the two groups. Parenting Stress of mothers were significantly lower for experimental group compare to control group. Parenting Self-efficacy of mothers were significantly higher for experimental group compare to control group. Conclusion: The above findings suggest that maternally administered Meridian massage should be applied clinical practice to improve growth of infants, emotional condition of mothers and interaction of infants and their mothers.

• Child Health Nursing Research
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• v.11 no.4
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• pp.381-389
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• 2005

Purpose: This study was done to investigate the effects of a massage program on the growth of premature infants and on the mothers' confidence and satisfaction in the mothering role. Methods: The participants were 29 mothers of premature infants hospitalized in a neonatal intensive care unit at CNU Hospital (14 in the massage program group and 15 in control group). Massage was done for 10-15 minutes, 2-3 times a day for 4 weeks. The data were using the SAS PC+ program. Result: Significant differences were found in the ratios of weight gain (Z=2.24, p=.013), grow in length (Z=2.50, p=.006) and increase in head circumference (Z=1.91, p=.028) between the massage program group and the control group. Confidence in the mothering role was significantly higher for mothers in the massage program group compared to those in the control group (Z=2.69, p=.004), but there was no significant difference in satisfaction with the mothering role between the two groups (Z=.88, p=.191). Conclusion: These results suggest that the massage program enhances growth of premature infants as well as enhancing the mother's confidence in her role as mother. Therefore, the massage program for premature infants can be use as an effective nursing intervention.

• Child Health Nursing Research
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• v.9 no.3
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• pp.259-271
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• 2003

Purpose: The purpose of this study was to evaluate the effectiveness of sensory stimulation therapy on the physical growth and behaviors of infants accommodated at two Korean orphanages. Method: Thirty-eight full term infants were assigned to a control (n=20) or an experimental (n=18) group within 14 dys of birth. In addition to routine orphanage care, infants in the experimental group received 15 minutes of massage twice a day, 5 days a week for 4 weeks. Result: Compared to the control group, the experimental group had gained significantly more weight and had larger increases in length and head circumference after the 4-week intervention period. In addition, the experimental group showed significantly better behavioral performance in the scoring of habituation (e.g., light), motor (e.g., motor maturity), and state range (e.g., peak of excitement, rapidity of build-up) behavioral clusters of Brazelton's NBAS. Conclusion: These data demonstrate that sensory stimulation therapy may facilitate the physical and behavioral development of the newborn infants placed in the orphanages.