• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.6 no.1
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• pp.138-143
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• 1996

After oral administration of 14C-labelled $N^G$-mono[methyl-14C]-L-arginine into rats, 38.2 % and 14.7 % of the administered radioactivity bad been recovered in the urine and stool during 10 days. In the urine, 59.4 % of the radioactivity was recovered in the first 24-hours and used for the indentification of the formation of methylamine. The strong cation-exchange resin column chromatography showed 6.3 %, 7.4 %, 4.9 %, and 81.5 % of the distributions of radioactivity of the neutral, monomethylamine, basic, and uneluted portions, respectively. The radioactivity of monomethylamine portion reeluted into the column chromatography was 39.5 %. The radioactivities corresponding monomethylamine in the column chromatography, thin-layer chromatography, and thin-layer electrophoresis were 39.5 %, 37.3 %, and 28.8 % of the recovered radioactivity, respectively.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.27 no.3
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• pp.149-162
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• 2017

Objectives: Six cases of non-oral occupational methanol poisoning were found in mobile phone parts manufacturers in South Korea during the period from 22 January 2016 to 5 October 2016. We conducted this study to determine the cause of the accident including social environment factor. Methods: We interviewed the cases. Based on that, we described this poisoning accident narratively and arranged the evolution of the accident in chronological order. We used the Haddon matrix method to investigate the cause of the accident. Results: It was found that six cases were all dispatched workers who were under poor working condition including working time exceeded 12 hours a day, not given basic occupational health and safety information etc. Occupational disease associated with dispatched work was difficult to be reported. 2 cases were not able to identify the cause of the disease within one year. Conclusions: In short, the direct cause of the poisoning accident was that workers were exposed to high concentration of methanol(over 1,000 ppm). One of the main fundamental cause is that dispatched worker is rampant in the supply chain of mobile phone production. To protect dispatched workers, appropriate occupational safety health measures are needed urgently.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.12 no.6
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• pp.2629-2635
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• 2011

This study carried out questionnaire survey and experiment on oral hygiene effects according to the actual condition of using oral care products and the amount of toothpaste used targeting 40 freshmen and sophomores in dental hygienics in some universities from November 8, 2010 to November 26. The collected data was analyzed by using SPSS WIN 15.0 program. The following conclusions were obtained. 1. The result of actual condition of toothbrushing is as follows. As the answer of a question about whether or not toothbrushing after every meal at ordinary times, the largest was 47.5% of being average. The occasion of toothbrushing before going to bed at ordinary times was the largest with 47.5%. The daily toothbrushing frequency was 3 times mostly and the general toothbrushing method at ordinary times was a rolling method. The frequency of exchanging toothbrushes for the past 1 year was 3 times, which is the largest with 45.0%. 2. As a result of the actual condition of using oral care products, the majority of students don't use electric toothbrush, interdental brush, or mouth-rinse except dental floss. Accordingly, there need to be education and promotion with diverse methods so that a patient oneself can prevent oral disease by selecting and using oral care products that are proper for each individual. Also, it was indicated that there is no big difference in oral hygiene effects depending on the amount of toothpaste used. Thus, to avoid wasting toothpaste, we need to educate and promote to use the amount of toothpaste under 0.3g.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.15 no.4
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• pp.2244-2255
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• 2014

This study aimed to compare smoking, drinking, dietary management, personal hygiene, and oral care between immigrant women in urban and rural areas and to determine predictors of the overall health behaviors. With the standardized questionnaire used for community health survey data collection was performed in 128 immigrant women from November 2011 to October 2012. Rural women performed significantly higher numbers of health behaviors than urban women and residential district, education, employment status, and perceived difficulties related to cultural adaptation significantly predicted health behaviors in immigrant women. Immigrant women in urban areas may be highly vulnerable in maintaining health behaviors compared with rural women and cultural barriers may hinder positive health behavior maintenance. Therefore, careful considerations at individual, community, and environmental levels are needed when assessing immigrant women's health behaviors and designing culturally relevant interventions to improve health status.

• Toxicological Research
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• v.35 no.2
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• pp.137-154
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• 2019

Triclosan (TCS) is an antimicrobial compound used in consumer products. The purpose of current study was to examine toxicology and risk assessment of TCS based on available data. Acute toxicities of oral, transdermal and inhalation routes were low, and phototoxicity and neurotoxicity were not observed. Topical treatment of TCS to animal caused mild irritation. TCS did not induce reproductive and developmental toxicity in rodents. In addition, genotoxicity was not considered based on in vitro and in vivo tests of TCS. It is not classified as a carcinogen in international authorities such as International Agency for Research on Cancer (IARC). No-observed-adverse-effect level (NOAEL) was determined 12 mg/kg bw/day for TCS, based on haematoxicity and reduction of absolute and relative spleen weights in a 104-week oral toxicity study in rats. Percutaneous absorption rate was set as 14%, which was human skin absorption study reported by National Industrial Chemicals Notification and Assessment Scheme (NICNAS) (2009). The systemic exposure dosage (SED) of TCS has been derived by two scenarios depending on the cosmetics usage of Koreans. The first scenario is the combined use of representative cosmetics and oral care products. The second scenario is the combined use of rinse-off products of cleansing, deodorants, coloring products, and oral care products. SEDs have been calculated as 0.14337 mg/kg bw/day for the first scenario and 0.04733 mg/kg bw/day for the second scenario. As a result, margin of safety (MOS) for the first and second scenarios was estimated to 84 and 253.5, respectively. Based on these results, exposure of TCS contained in rinse-off products, deodorants, and coloring products would not pose a significant health risk when it is used up to 0.3%.

• Journal of Korean Academy of Nursing Administration
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• v.12 no.3
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• pp.464-472
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• 2006

Purpose: The aim of this study was to define the health problem in the community-dwelling elderly of Korea and to compare differences of CAPs(Client Assessment Protocols) by characteristics. Method: Data was collected by visiting nurse from 556 elderly over 65 years in selected metropolitan areas. To evaluate the functional state of elderly in the community, I used "RAI-MDS HC; Residental Assessment Instrument Minimum Data Set-Home Care(2.0 version)" and established information exchange system among resources, by developing the data into a computer program. Results: The health problem of 'preventive health measures' was the largest(99.6%), and then 'health promotion(85.3%)', 'visual function(75.5%)', 'psychologic drug(68.9%)', 'pain(68.5%)', ‘social function(59.2%)', 'communication disorders(56.2%)', 'environmental assessment(53.2%)', 'depression & anxiety(46.9%)', 'oral health(43.4%)' followed. The number of health problems was average 10.16 in the community-dwelling elderly. Conclusion: The results suggest the need to emphasize the importance of assessment of the health problem of the elderly. We can apply it in the distribution of community resources and the development of service providing programs by figure out the health problem and resource in need for the elderly in the community.

• Journal of Preventive Medicine and Public Health
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• v.15 no.1
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• pp.131-137
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• 1982

For the purpose of the curative effects of oral D-penicillamine in lead poisoning, D-penicillamine was orally administered to 7 lead poisoned workers which were employed in glaze product industry dealing with the lead oxide ($Pb_3O_4$). The doses of D-penicillamine was 1,200mg per day which was administered by oral 7days schedules, taking for 5 days and stopping for the following 2days, repeatedly during 3 months period. (All the poisoned workers started working again in that industry after 1 month treatment, and were treated by oral D-penicillamine for 2 months still being exposed to contaminated environment.) In order to evaluate the curative effects of D-penicillamine, 10gm of whole blood and 24 hours urine were collected every 14 days during the curative period for laboratory analysis(hemoglobin, blood lead, urine $\sigma$-aminolevulinic acid, urine coproporphyrin, and urine lead levels) with the observation of the clinical symptoms. The results were as follows; 1. Oral D-penicillamine effected good curative results as that hemoglobin, blood lead, urine $\sigma$-aminolevulinic acid, and urine coproporphyrin levels were decreased below the critical level within 1 month treatment. 2. After re-exposure, oral D-penicillamine effected to some extent as that urine lead level was decreased below the critical level after 3 months treatment with disappearence of the clinical symptoms after 2 months treatment. However, the curative effects of oral D-penicillamine in the lead exposure state is questionable since increasement of blood lead level and remarkable decreasement of urine lead level after 3 months treatment can be observed.

• Journal of Environmental Health Sciences
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• v.42 no.3
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• pp.205-212
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• 2016

Objectives: The objective of this study was to evaluate the distribution of blood lead concentrations of residents in the areas surrounding an industrial complex. Methods: During the three-month period from August to October 2012, informed consent was obtained from a total of 417 residents in Gwangyang and Yeosu. We collected blood samples from all subjects, and their demographic characteristics were acquired using a questionnaire. The blood samples were analyzed using an atomic absorption spectrometer and data analysis was conducted using IBM SPSS version 21.0. Results: The geometric mean concentration of blood lead in all subjects was $1.85{\mu}g/dL$. The highest (p<0.01) blood lead concentrations were in the current drinking group ($2.24{\mu}g/dL$). Blood lead concentrations in the smoking group ($0.59{\mu}g/dL$) were significantly (p<0.05) higher than those in the non-smoking group ($0.24{\mu}g/dL$). Risk assessment was performe using the Korean National Environmental Health Survey (KNEHS) as a reference. The hazard indices of blood lead in males and females were 0.65 and 0.52, respectively Conclusion: We provided baseline data for reference values of toxicity and heavy lead concentrations. Our results might be useful for further evaluation of risks due to exposure to heavy metals via oral, air, and percutaneous routes.

• Journal of dental hygiene science
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• v.8 no.4
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• pp.225-231
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• 2008

The purpose of this study was to examine the relationship between oral health habits and oral diseases in an attempt to raise awareness of the need for prolonged dental checkup projects and lay the foundation for oral health education and sustained oral health care projects. The subjects in this study were 2,643 workers from 76 workplaces in Siwha Industrial Complex in the city of Ansan, Gyeonggi province, who were at the age of 20 and up. The findings of the study were as follows: 1. Concerning the experience of visiting a dental clinic over the past year, 760 male workers (37.4%) and 237 females (38.9%) visited dental clinics in the past year. By age group, those who were in their 50s (54.0%) visited dental clinics the most, and the workers in their 30s (67.9%) paid a visit the least. The gap between the age groups was statistically significant (p < 0.001). 2. In regard to the time for toothbrushing by age group, the workers in their 20s (64.6%) made up the largest group that brushed their teeth before breakfast, and those who were in their 60s and up constituted the greatest group that did toothbrushing after breakfast. The workers in their 20s brushed their teeth the least, as the rates of the workers of this age group who did toothbrushing after breakfast and dinner respectively stood at 64.0 percent and 54.5 percent. The disparities between the age groups were statistically significant (p < 0.001). 3. As for scaling experience for the past year, 302(46.0%) out of the workers who got their teeth scaled in the past year had periodontal diseases, and 1,600(80.6%) out of those who didn't suffered from periodontal diseases. The gap between them was statistically significant (p < 0.001). 4. Regarding the relationship of subjective oral health state to dental caries among the workers without dental caries, the largest group that numbered 327(54.1%) considered themselves to be in good oral health. In the event of the workers with dental caries, the greatest group that numbered 708(75.5%) found themselves to have one or more carious tooth(teeth). The disparity between them was statistically significant (p < 0.001). 5. As for connections between dietary habits and dental caries, those who had dental caries (2.29) showed a greater preference for snack than the others who hadn't (2.21). The preference for snack made a bigger statistically significant difference to dental caries than the other dietary habits (p < 0.05).

• Proceedings of the KAIS Fall Conference
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• 2009.05a
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• pp.128-130
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• 2009

본 논문은 임신의 시기가 내분비계의 변화로 인한 프로게스테론의 과잉분비가 발생하여 혈관의 투과성을 항진시켜 구강내의 잇몸 부종, 잇몸 출혈 등을 유발하고, 입덧으로 인한 메쓰꺼움, 몸의 무거움과 나른함, 음식 기호변화, 간식횟수의 증가 등을 겪게 되어 신체뿐 아니라 구강 환경 또한 변화하게 된다는 여러 관련 자료들을 근거로 임산부의 구강 건강상태와 구강보건인식을 파악하고자 2008년 12월 15일 ~ 2009년 1월 30일까지 180명의 임산부를 대상으로 구강건강상태와 구강보건인식에 대한 조사를 실시하였다. 설문의 결과 임산부의 생활수준, 분만경험, 임신시기에 따라 생활수준이 좋을수록, 분만경험이 없는 경우에서, 4-6개월 임신시기 시 구강건강상태에 대하여 유의미한 차이가 나타났다. 건강한 구강건강을 위한 우선 행위인 잇솔질에서의 교육 수준별, 생활 수준별, 임신 시기별로 식사 후 3회 정도의 잇솔질의 횟수가 유의미한 차이의 결과를 나타내었으며, 잇솔질시 오심과 구토로 잇솔질이 어려운 임산부들의 구강상태 청결을 위해 사용되어지는 보조구강위생용품으로는 치실, 구강 양치액, 혀 클리너, 치간 칫솔이 사용된다는 결과가 나타났다. 이러한 결과의 자료들은 임신 시기 중 가장 고민된다고 답하여준 구강건강 부분에서의 입덧으로 인한 잇솔질의 어려움, 잇몸출혈, 충치, 치석제거, 구강질환 치료의 적정시기, 구취 등의 부분을 임산부 대상의 구강보건교육 시 기존의 자료에 조금 더 중점적으로 다루어져야 하는 부분임을 확인할 수 있었다.