• 제목/요약/키워드: individualized medicine

검색결과 193건 처리시간 0.025초

산탄총에 의한 좌측 안면부 손상 환자의 치험례 (증례보고) (REPORT OF THE MANAGEMENT OF GUNSHOT WOUNDS TO THE LEFT FACE)

  • 김일규;이상선;오성섭;최진호;김형돈;오남식
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • 제26권2호
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    • pp.224-227
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    • 2000
  • Gunshot wounds to the face are often dramatic at the time of presentation. Although care must be individualized, protocol approach helps the clinician rapidly evaluate patient and plan treatment. Early X-ray films help to determine the precise trajectory. Rapid neurologic assessment and early CT scanning based on physical examination ot trajectory will allow for identification of even occult injuries early. Lead poisoning arising from bullet lead in the synovial cavity of the hip, synovial cavity of the chest and pleural space have been reported. A combination of surgical debridement and chelation therapy with oral succimer produce a satisfactory outcome. We have managed a patient with Lt facial gunshot wound and Lt mandible angle fracture by open reduction of angle fracture and surgical removal of remnant bullet and medially advanced cheek skin flap. We have obtained good result and report this case with review of literatures.

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발병과 재발에 한약으로 관해가 유도된 크론병 증례 보고 (Remissions of Crohn's Disease at Onset and Relapse Using Herbal Medicine: A Case Report)

  • 이병희;원지윤;박재량;이향숙
    • Korean Journal of Acupuncture
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    • 제37권3호
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    • pp.183-190
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    • 2020
  • This case report details two remissions at onset and relapse after 4 years each with Korean herbal medicine treatment in a 33-year-old male patient diagnosed as Crohn's disease (CD) by clinical and colonoscopic examination. He presented bloody diarrhea and severe abdominal pain, and his symptoms were persistent even with usual Western medications, so he was offered surgery and biologics. He was then given Sayeok-Tang for 8 months and remission was induced. Four years later he had a relapse and this time he was given Banha-Sasim-Tang, and Baekduong-Ga-Gamcho-Agyo-Tang, based on pattern changes with intense symptom monitoring. Clinical and endoscopic remission was confirmed after 4 months of herbal medicine treatment and no adverse events were reported. This case report shows that individualized Korean herbal medicine treatment has the potential for induction of remission of CD and further research is warranted.

스포츠 활동과 연관된 슬개대퇴 관절 손상의 보존적 치료 (Patellofemoral Joint Injuries in Sports Activity - Conservative Treatment -)

  • 전철홍
    • 대한정형외과스포츠의학회지
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    • 제5권1호
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    • pp.9-16
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    • 2006
  • 슬개대퇴 관절의 재활의 목표는 수상된 하지의 기능적인 통일성을 회복하는 것이다. 환자의 개별적인 문제를 파악하여 단계적인 재활 치료를 선택해야 하고 대부분 보존적 치료에 잘 반응하므로 적극적인 재활치료가 요구된다 환자의 재활 치료프로그램의 효율성을 평가하고 부정적인 영향 여부를 알기 위해서 주관적 및 객관적으로 환자의 진행 과정을 계속적으로 감시해야 한다

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정신적 요인에 의한 역설적 성대운동 1예 (A Case of Paradoxical Vocal Fold Movement Due to Psychological Causes)

  • 신동민;박기철
    • 대한후두음성언어의학회지
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    • 제32권3호
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    • pp.142-145
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    • 2021
  • Paradoxical vocal fold movement (PVFM) is a dystonic laryngeal disorder characterized by involuntary vocal fold adduction during inspiration and/or expiration. PVFM is uncommon and may aggravate airway obstruction. And patients with PVFM have a specific etiology; therefore, treatment must be individualized and given immediately. We present a case of 63-year-old male presenting with intermittent dyspnea. After multidisciplinary workup, we presumed psychogenic PVFM and evaluated with speech-language pathologist and psychologist. In this report, we describe a rare case of psychogenic PVFM patient.

비만 환자에서의 맞춤형 영양 상담과 식사 치료 (Nutrition Counseling and Tailored Dietary Intervention for Patients with Obesity)

  • 강서영
    • 비만대사연구학술지
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    • 제2권1호
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    • pp.11-16
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    • 2023
  • Nutrition counseling and dietary intervention are essential to obesity management because weight reduction is the consequence of negative energy balance. The first step of the nutrition counseling in patients with obesity is thorough evaluation of the nutritional status. During the nutritional evaluation, amount of energy consumption, dietary habits, and medical and socioeconomic factors influencing diets should be evaluated. Diet interventions including low calorie diet, low fat diet, low carbohydrate diet, and high protein diet are all effective in weight reduction as long as decrease in energy consumption is accompanied. Amount of energy restriction and choice of diet interventions should be individualized based the medical condition and characteristics of each patient.

Effects of Individualized Intensive Physical Therapy for a Child with MECP2 Duplication Syndrome: A Case Study

  • Chang-Ho Kim
    • 대한물리의학회지
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    • 제18권4호
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    • pp.29-35
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    • 2023
  • PURPOSE: High-intensity physical therapy may help improve some gross motor developmental delays through an increased treatment frequency. This study describes an increase in physical therapy frequency and intensity over an eight-week time frame for a child with a rare genetic neurodevelopmental disorder. METHODS: A single-subject research was performed. The subject was a nine-year-old boy with MECP2 Duplication Syndrome. The outcome measure consisted of one time before and after the intervention. An intensive physical therapy program was applied to this subject. The treatments included reciprocal crawling, high kneeling, tailor sitting, weight-bearing and shifting training to facilitate ankle balance strategies and training to walk without assistance. RESULTS: After the eight-week follow-up, the child achieved a gradual improvement in the gross motor function measures, and the mother reported that the child frequently engaged in tailor sitting and independently walking. CONCLUSION: This case study highlights that intensive physical therapy improved the overall motor function of a child with MECP2 duplication syndrome.

Diagnosis and management of neurogenic orthostatic hypotension

  • Woohee Ju;Dong In, Sinn
    • Annals of Clinical Neurophysiology
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    • 제25권2호
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    • pp.66-77
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    • 2023
  • Orthostatic hypotension is a sustained and pathological drop in blood pressure upon standing. Orthostatic hypotension can be due to non-neurogenic conditions or autonomic disorders. Impaired baroreflex-mediated vasoconstriction and insufficient release of norepinephrine play key roles in the pathophysiology of neurogenic orthostatic hypotension. Its common symptoms mainly related to inadequate cerebral blood flow include dizziness, lightheadedness, and syncope. It is crucial to differentiate neurogenic orthostatic hypotension from non-neurogenic orthostatic hypotension. For the management of neurogenic orthostatic hypotension, physicians should implement non-pharmacological methods and, if possible, reverse combined non-neurological conditions. Depending on severity of symptoms, pharmacological intervention may be tried after or with non-pharmacological methods. Its management should be individualized based on intensity of symptoms, comorbid conditions, drug side effects, and etiology. In this review, we discuss the definition, pathophysiology, clinical approach, and management of neurogenic orthostatic hypotension.

초등학교 보건교사의 보완대체요법 적용 경험 (Experience of School Health Instructors in the Application of Complimentary and Alternative Medicine)

  • 김영혜;김현수;조영란
    • Child Health Nursing Research
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    • 제13권3호
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    • pp.247-256
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    • 2007
  • Purpose: This study was done to examine the experience of school health instructors in applying complimentary and alternative medicine (CAM). Method: The participants were 215 health instructors working in elementary schools in Busan. Data were collected from Dec. 1, 2004 to Mar. 10, 2005 and were analyzed using SPSS WIN 10.0. Results: Most of the health instructors had knowledge about CAM. Among the various CAM methods, acupuncture was the most widely known at 78.6%. While 53.5% had no experience in CAM education, 46.5% had been trained. Slightly over half (52.1%) had used CAM at school and based their decision on personal experience. As to applicability of CAM at school, 72.1% thought CAM was applicable, and 78.7% of this group considered alleviation of symptoms and assistance in the treatment process as the reasons for their answer. There were significant differences in responses as to the applicability of CAM according to age (p=.002), work experience (p=.004) and educational background (p=.002). Conclusions: The above results suggest that there is a need to develop a professional education program on complimentary and alternative medicine to assist school health instructorsto plan nursing interventions using CAM which are individualized and practical.

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기분부전장애와 비전형우울증의 약물치료 (Pharmacological Treatments for Dysthymic Disorder and Atypical Depression)

  • 임세원;오강섭
    • 생물정신의학
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    • 제14권1호
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    • pp.14-20
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    • 2007
  • Objectives : The diagnosis of depression is based on a highly variable set of symptoms. Therefore, depression should not be viewed as a single disease, but a heterogenous syndrome comprised of different pathophysiologies. There are several subtypes of depression which were already incorporated in DSM-IV. This article provides a systematic review of pharmacological treatments of two recognized subtypes of depression-dysthymic disorder and atypical depression. Methods : Systematic search of relevant literatures on dysthymic disorder and atypical depression was performed by proposed search strategy of the Clinical Research Center for Depression of Korean Health 21 R&D Project. All identified literatures were carefully reviewed and classified according to SIGN grading system and summarized in a narrative manner. Results : For the treatment of dysthymic disorder and atypical depression, selective serotonin reuptake inhibitors( SSRIs) and moclobemide have more evidence than the other antidepressants. SSRIs and moclobemide showed superior tolerability than tricyclic antidepressants. Conclusions : The authors proposed treatment recommendations for dysthymic disorder and atypical depression by the methods of evidence-based medicine(EBM). However, guideline developing methods of EBM also have several inevitable limitations. Therefore, in the absence of clear and significant differences in efficacy, the choice of medication must be individualized for a particular patient based on psychiatrist's own clinical decision.

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맞춤의학 시대의 개인 유전체 서열의 해독과 스마트한 이용 (Individual Genome Sequences and Their Smart Application In Personalized Medicine)

  • 김동민;정해영;김일철;원용관
    • 스마트미디어저널
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    • 제2권4호
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    • pp.34-40
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    • 2013
  • 다양하고 빠른 차세대 유전체 서열 분석기를 사용한 개인 유전체 분석은 생명과학 연구뿐만 아니라 질병의 진단과 치료를 포함하는 의학 분야까지 새로운 지평을 열고 있다. 저렴한 비용으로 읽혀진 개인 유전체 서열은 통합 과정을 거쳐 유전체 이상을 점검할 수 있고, 얻어진 서열 데이터는 유전자 변이성 연구, 유전체 발현 연구, 후성유전학적 연구, 유전체 주석화 등에 이용될 수 있다. 개인 유전체 데이터는 생물학적 연구 결과와 임상 연구 데이터를 연계하여 질환 위험도의 예측과 맞춤 치료에 이용할 수 있게 되었다. 개인 맞춤의학 시대에 전문적 데이터와 일반인 사용자의 간극을 메우기 위해 스마트 미디어 기기와 같은 적극적인 인터페이스의 개발이 시급하다.

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