• 한국융합학회논문지
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• 제10권2호
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• pp.309-313
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• 2019

본 연구는 여러 형태의 복부 운동(crunch, spine V-up, prone V-up on ball, prone V-up on slide board, prone V-up on TRX, and prone V-up power wheel)을 하는 동안 URA, LRA, IO, EO and RF의 EMG 반응을 조사했다. 대상자들은 이러한 운동을 수행하는 동안 복근의 isometric contraction을 수행했다. 테스트 결과 EO, URA, LRA는 어떠한 운동 간에도 통계학적으로 유의한 차이가 없었다. 하지만, IO를 검사 시에, 양와위 V-up운동은 slide운동 시 보다 유의하게 더 큰 근활성도를 보여주었다. 또한, crunch동안 EMG활성도는 다른5가지 어떠한 운동보다 현저히 적었다. 이러한 결과들은 등척성 복근 운동 시행 시에 장비가 없는 기반 운동이 장비 기반 운동과 유사하게 자극을 준다는 것을 나타낸다. 코어 강화는 오래 동안 운동 컨디셔닝과 수행능력의 핵심 구성 요소로 알려져 왔다. 복부 근육 조직은 개인의 코어를 구성하는 5가지 중 하나의 구성요소로 여겨진다. 복부 근육은 또한 요추의 적정한 기능을 보장한다. 모든 복부 근육이 요추 안정화에 기여하지만, TA & IO가 주요한 안정화(stabilizers)를 하는 것으로 보여주었다.

• 운동과학
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• 제26권2호
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• pp.103-114
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• 2017

INTRODUCTION: Regulation of skeletal muscle protein mass is implicated not only in exercise performance but in metabolic health. Exercise in combination with nutrition, particularly dietary protein/amino acid intake, are the pragmatic approach that effectively induces muscle anabolic response (i.e., muscle hypertrophy) through regulating protein synthesis and breakdown. PURPOSE: The purpose of this review was to summarize available data on the effect of exercise intervention and amino acids intake on muscle protein synthesis and breakdown and provide an insight into development of an effective exercise intervention and amino acids supplements, applicable to training practice. METHODS: In this review, we have reviewed currently available data mainly from stable isotope tracer studies with respect to the effect of exercise intervention and protein or amino acid supplement on muscle protein anabolic response. CONCLUSIONS: Taken together, exercise alone may not be effective in achieving a positive net muscle protein balance due to the fact that protein breakdown still exceeds protein synthesis until nutrition intake such as protein/amino acids. It appears that muscle anabolic response increases in proportional to the amount of protein intake up to 20 - 35 g depending on quality of protein, age, differences on exercise intensity, duration, and frequency, and individual's training status

• Journal of the Korean Wood Science and Technology
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• 제49권4호
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• pp.371-383
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• 2021

Plant essential oils are used in products such as fragrances and cosmetics due to their individual aromatic characteristics. Currently, essential oils are not only used in cosmetics but also in pharmaceutical products with anti-bacterial, anti-viral, anti-fungal, anti-parasitic, insecticidal, anti-cancer, neuroprotective, psychophysiological, or anti-aging effects. Despite their pharmaceutical properties, some studies reported cytotoxic effects in high doses. Therefore, for pharmaceutical purposes, the margin of safety of essential oils needs to be examined. Herein, we evaluated the IC₅₀ of 10 essential oil from Korean native plants: Juniperus chinensis L. var. sargentii Henry, Citrus natsudaidai Hayata, Citrus reticulata Blanco, Citrus unshiu (Yu. Tanaka ex Swingle) Marcow, Artemisia capillaris Thunb, Aster glehnii F. Schmidt, Juniperus chinensis L, Zanthoxylum schinifolium Siebold & Zucc, Zanthoxylum piperitum (L.) D, and Cinnamomum loureirii. In addition, gene regulation of the cell-cycle gene and apoptosis marker CASP3 was examined at the IC₅₀ level. The purpose of this study was to describe the toxic concentrations of essential oils extracted from Korean native plants, thereby providing toxic concentration guidelines for inclusion in a toxicity database and in the application of plant essential oils in various fields.

• 동의생리병리학회지
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• 제35권1호
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• pp.42-46
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• 2021

The purpose of this study was to investigate the relationship between sleep quality and sleep duration according to individual characteristics, and the relationship between sleep quality and cold type. A total of 1998 participants aged 30-55 who participated in a community cohort study at KIOM's Oriental Medicine Data Center (KDC) was analyzed. Cold type was diagnosed with a common the Questionnaire of Cold Pattern Identification (8 items). Sleep quality was assessed by the Pittsburgh Sleep Quality Index. The participants in this study were classified into 1193 with cold type and 805 with non-cold type. The poor sleep quality was found in more women than men, and the Body Mass Index (BMI) was higher in the non-cold type. In the cold type group, average sleep quality was poor and sleep duration was short. There was a statistically significant correlation between cold score, sleep quality, and sleep duration. Cold type was related to the sleep quality. The risk of poor sleep quality increased 1.46 with increased cold type (95% CI = 1.16-1.84, p <.001). In particular, it was found that various programs to improve the quality of sleep, focusing on the cold type among personal characteristics, are needed to maintain adequate sleep to improve the sleep quality. In the future, when analyzing the relationship between cold type and sleep quality, it is thought that an attempt to derive other objective quantitative indicators is needed.

• 한국발생생물학회지:발생과생식
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• 제24권4호
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• pp.263-275
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• 2020

The proper administration of melatonin has well been documented to induce testicular regression in seasonal breeding animals. The subcutaneous injections of melatonin in the afternoon, not in the morning, consistently occurred testicular involution in the male Syrian (golden) hamsters whose reproductive activity is regulated by the photoperiod. But the effects of daily melatonin via gavage have not been estimated. Golden hamsters housed in long photoperiod (LP) were divided into 5 groups: the control animals housed in LP or in short photoperiod (SP) and animals treated daily with low (15 ㎍), middle (150 ㎍), and high dosages (1,500 ㎍) of pure melatonin by using gavage in the evening for 8 weeks. As results, LP control animals had large testes and SP controls displayed small and entirely regressed testes. The animals treated with various dosages of melatonin showed collectively degenerating effects on the weights of testes, epididymides, and seminal vesicles in the middle and high dosage groups, with the individual differences as well. The high dosages induced testicular regression in more proportion than the middle dosages did. The low dosage had large testes like the LP control animals. The small and inactive testes shown in some animals of both middle and high groups presented the complete regression as those of the animals maintained in SP. These results strongly suggest that the administrations of melatonin lead to testicular involution in the male golden hamsters when it is administered through gavage.

• 인간식물환경학회지
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• 제24권1호
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• pp.1-16
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• 2021

Background and objective: People-nature experiences, which suggest that humans seek connections between nature and other forms of life, were presented by biologist E. O. Wilson in 1984. Biophilic design attributes support environments that can improve human connections to nature. A significant amount of literature on environmental psychology provides empirical evidence that nature benefits humans, and that practical landscape and built environments can be designed to link humans and nature (e.g., the 14 biophilic design patterns). To date, however, there has been no well-done research on reviewing the health benefits of biophilic design. Methods: The paper provides a narrative review on biophilic design and human health. The scope of this article is limited to biophilic-design books and peer-review articles related to "biophilic design," "evidence-based," "benefits," "health," rather than an attempt to identify universal issues with biophilia hypothesis. Results: A total of 45 papers were included in our review, which was related to the top five biophilic design patterns and design: the presence of natural images, the presence of plants, visual and non-visual connections to nature, and material connection with nature. These studies were related to physiology and psychology through direct or indirect connections with nature and experiences in space and place. Conclusion: This study presents two important comparisons of the empirical research on biophilic design and human health that can explain the relationship of people-nature experiences to biophilic design and human health and provides insights into related researches and recommendations for future application of our findings.

• Clinical and Experimental Reproductive Medicine
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• 제49권1호
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• pp.49-56
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• 2022

Objective: Oxidative stress and sperm DNA fragmentation (SDF) have been linked to idiopathic male infertility (IMI). Various antioxidants have been tried to improve semen parameters and fertility potential in IMI patients, but with inconsistent results. The study aimed to compare the effects of coenzyme Q10 (CoQ10) and Centrum multivitamins on semen parameters, seminal antioxidant capacity, and SDF in infertile men with idiopathic oligoasthenospermia (OA). Methods: This prospective controlled clinical study involved 130 patients with idiopathic OA and 58 fertile controls. The patients were divided randomly into two groups: the first group received CoQ10 (200 mg/day orally) and the second group received Centrum multivitamins (1 tablet/day) for 3 months. Semen parameters, CoQ10 levels, reactive oxygen species (ROS), total antioxidant capacity (TAC), catalase, SDF, and serum hormone levels (follicle-stimulating hormone, luteinizing hormone, testosterone, and prolactin) were compared at baseline and after 3 months. Results: Both CoQ10 and Centrum improved sperm concentration and motility, but the improvement was greater with Centrum therapy (p<0.05). Similarly, both therapies improved antioxidant capacity, but TAC and catalase improvement was greater (p<0.01 and p<0.001 respectively) with CoQ10, whereas ROS (p<0.01) and SDF (p<0.001) improvements were greater with Centrum administration. Centrum therapy was associated with reduced serum testosterone (p<0.05). Conclusion: In conclusion, both CoQ10 and Centrum were effective in improving semen parameters, antioxidant capacity, and SDF, but the improvement was greater with Centrum than with CoQ10. Therefore, Centrum-as a source of combined antioxidants-may provide more effective results than individual antioxidants such as CoQ10 in the treatment of infertile men with idiopathic OA.

• 운동과학
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• 제28권1호
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• pp.82-90
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• 2019

PURPOSE: The purpose of this study was to examine the association of waist to height ratio (WHtR) and resting heart rate (RHR) with cardio-metabolic risk factors among Korean postmenopausal women. METHODS: A cross-sectional analysis was performed using the 2015 Korea National Health and Nutrition Examination Survey. The analysis included a total of 1,540 postmenopausal women. RESULTS: Individuals with higher WHtR (>0.56) showed significantly higher glucose, triglyceride, insulin, Homeostatic Model Assessment for Insulin resistance (HOMA-IR), total cholesterol, systolic and diastolic blood pressure compared with ones with lower WHtR (≤0.51). Similar findings were found in those with higher RHR (≥90 bpm) compared with ones with lower RHR (<60 bpm) for glucose and HOMA-IR. When determining the combined effects of WHtR and RHR on the prevalence of metabolic syndrome, individual with WHtR above 0.5 and RHR above 80 bpm showed 10.39 times higher prevalence of metabolic syndrome compared with those with WHtR below 0.5 and RHR below 70 bpm. We further performed multiple linear regression analysis to understand how WHtR and RHR contribute to fasting glucose, and found that both WHtR and RHR contribute to fasting glucose levels independent of age, education level, marital status and income level. CONCLUSIONS: The current study showed that the WHtR and RHR are associated with cardio-metabolic risk factor and prevalence of metabolic syndrome in Korean postmenopausal women.

• 비교문화연구
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• 제44권
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• pp.411-430
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• 2016

영국 빅토리아 시대에 활성화된 문학과 과학 연구에서 뜨거운 논쟁 중 하나는 생리학과 심리학의 연관관계를 규명하는 것이다. 당시 많은 사상가들이 심리적 현상이 그것의 생리학적 원인으로 환원될 수 있는가의 여부에 대해 대단한 관심을 보였다. 예컨대 윌리엄 벤자민 카펜터(Willaim Benjamin Carpenter)는 심리라는 정신 현상은 생리라는 육체 현상과 근본적으로 다르다고 주장하고, 그랜트 알렌(Grant Allen)은 심리적 현상은 그것의 생리적 원인으로 환원될 수 있다고 여겼다. 본 논문에서는 알렌의 "생리학적 미학"(1877)에 나타난 생리학적 환원주의를 비판하고자 한다. 그의 미학은 대단한 역설을 품고 있다. 미적 인식의 점진적 발전을 주장하는 진화론적 미학을 주장하지만 궁극적으로는 이런 미적 발전 단계 구분을 부차적인 것으로 여기고 생리학적 보편주의를 제시하기 때문이다. 색깔에 대한 미적 판단의 진화를 예로 들면, 알렌은 인류 진화의 초기에는 화려한 색깔을 선호하다가 점진적으로 차분한 색깔로 '자연선택' 된다고 말한다. 색깔 선호의 이런 점진적 발전은 감각신경의 정교한 발전과 비례한다고 주장한다. 그러나 알렌은 궁극적으로 미적 인식의 이런 진화론적 발전 보다 미적 쾌락을 가능하게 하는 보편적으로 존재하는 감각신경 구조가 있다는데 더 큰 가치를 부여한다. 더 나아가 미적인 대상을 인식하는 방식에 있어서는 식물, 동물, 인간은 본질적으로 차이가 없다고까지 말한다. 미적 인식의 발전 단계를 설정하여 서열화하는 대신 누구에게나 존재하는 보편적 미적 감상 능력이 더 의미있다고 생각하는 미적 평등주의를 드러낸다. 이런 미적 보편주의는 인간에게 내재된 신경생리학적 구조의 보편성에 기인한다고 강조한다. 지적 판단이 개입되는 고차원적 미적 인식과 저급한 감각적 미적 인식의 차이는 질적 차이가 아니라 양적 차이일 뿐이다. 알렌이 정의하는 미적 사심 없음이라는 개념은 그의 이런 역설의 미학을 더욱 극명하게 보여준다. 그는 생리적-실용적 욕구에서 벗어나 그 자체의 쾌락을 추구하는 사심 없는 미적 판단을 최고 수준의 미적 인식이라고 말한다. 육체적-생리적-물질적-실용적 욕구에서 멀어지면 멀어질수록 미적 인식이 높다고 주장한다. 문제는 사심 없는 미적 관심이란 고차원의 미적 판단 능력도 결국은 신경 구조의 복잡한 발전에 기인한다고 보고 있어 다시 생물학적-생리학적 절대주의로 귀결한다. 필자는 알렌의 이런 모순된 주장을 생리학적 미학의 역설이라 부른다. 알렌의 미학은 사회적, 정신적 영역의 존재를 제대로 인정하지 않고 오직 신경-생리적 요인만을 절대화한다는 면에서 생물학적 순수주의를 표방한다. 현실은 물리적-생물학적 현실과 더불어 사회적, 개인적 요인들이 중층 결정된 구조인데 알렌은 이를 지나치게 단순화하여 생리학적 환원주의에 빠진다. 정치, 문화적 상황이나 개인적 취향의 다양성을 부차적인 요소로 과소평가하고 오직 육체적-생리적-감각적 요인만을 최우선시 하기 때문이다.

• 동의생리병리학회지
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• 제22권6호
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• pp.1359-1367
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• 2008

DSOM(Diagnosis System of Oriental Medicine) was made as a computerized assistant program for oriental medicine doctors to be able to diagnose with statistical basis. Then DSOM uses questionnaires filled out by subjects without enough explanatory guide. If the subject misunderstand the meaning of the passages, we might not rely on that result. So I designed this study to investigate the diagnostic correspondent rates between DSOM and practitioners. First, let the respondents answer to DSOM(DSOM-Ⅰ for the rest). After that, three doctors diagnosed the respondents and marked how much they had symptoms about 16 pathogenic factors in the score range 0${\sim}$5('0' means they didn't have that symptom, '1' means they had that symptom but mild, '3' means they had that symptom moderately, '5' means they had that symptom severely. And let the respondents answer to DSOM(DSOM-Ⅱ for the rest) again. Finally, we investigated the correspondent rates of diagnosis between DSOM-Ⅰ,Ⅱ and doctors'. We obtained conclusions as following. In the comparison of output frequency rate of the pathogenic factors, the difference between DSOM-Ⅰ and Ⅱ was 1%. In the correspondent rates of diagnosis between DSOM-Ⅰ,Ⅱ and doctors', In DSOM-Ⅰ and Ⅱ answered by subjects two times respectively, the correspondent rate was highest in insufficiency of Yang(陽虛) and liver(肝) as 93.2%, lowest in damp(濕) as 69.5% and showed 81.9% in all 16 pathogenic factors mean. In DSOM-Ⅰ and Ⅱ, and Doctors' diagnose, they showed the complete correspondent rates of 15.3${\sim}$61.0%, 15.3${\sim}$59.3% in individual pathogenic factor, 36.5%, 37.3% in all 16 pathogenic factors mean each, and within ${\pm}$1 errorrange, they showed the correspondent rates of 32.2${\sim}$93.2%, 35.6${\sim}$89.8% in individual pathogenic factor, 67.6%, 67.3% in all 16 pathogenic factors mean each, and within ${\pm}$2 error range, they showed the correspondent rates of 62.7${\sim}$98.3%, 71.2${\sim}$100% in individual pathogenic factor, 85.1 87.6%% in all 16 pathogenic factors mean each. In the correspondent rates of the severe case, In the cases that the Doctors' diagnostic score mean was over 3(the severity of disease is middle), there were deficiency of qi(氣虛), stagnation of qi(氣滯), blood stasis(血瘀), damp(濕), liver(肝), heart(心), spleen(脾) and they all showed the correspondent rates of over 60 except blood stasis(血瘀). In the cases that the weighed pathogenic factor was above 9, the correspondent rates were 50${\sim}$100%. deficiency of qi(氣虛), blood-deficiency(血虛), stagnation of qi(氣滯), blood stasis(血瘀), insufficiency of Yin(陽虛), insufficiency of Yang(陽虛), coldness(寒), heat (熱), damp(濕), dryness(燥), liver(肝), heart(心), spleen(脾), kidney(腎), phlegm(痰).