An, Hye-sun;Ko, Suhui;Bang, Ji Hwan;Park, Sang-Won
Infection and chemotherapy
/
v.50
no.4
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pp.319-327
/
2018
Background: Lancet-related needlestick injuries (NSIs) occur steadily in clinical practices. Safety-engineered devices (SEDs) can systematically reduce NSIs. However, the use of SEDs is not active and no study to guide the implementation of SEDs was known in South Korea. The lancet-related NSIs may be eliminated to zero incidence using a SED lancet with effective sharp injury protection and reuse prevention features. Materials and Methods: We implemented a SED lancet by replacing a conventional prick lancet in a tertiary hospital in a sequential approach. A spot test of the new SED was conducted for 1 month to check the acceptability in practice and a questionnaire survey was obtained from the healthcare workers (HCWs). A pilot implementation of the SED lancet in 2 wards was made for 1 year. Based on these preliminary interventions, a hospital-wide full implementation of the SED lancet was launched. The incidence of NSIs and cost expenditure before and after the intervention were compared. Results: There were 29 cases of conventional prick lancet-related NSIs for 3 years before the full implementation of SED lancet. The proportion of prick lancet-related NSIs among yearly all kinds of NSIs during two years before the pilot study was average 11.7% (22/188). Pre-interventional baseline incidence of all kinds of NSIs was 7.01 per 100 HCW-years. After the full implementation of SED lancet, the lancet-related NSIs became zero in the 2nd year (P = 0.001). The average direct cost of 18,393 US dollars (USD) per year from device and post-exposure medical care before the intervention rose to 20,701 USD in the 2nd year of the intervention. The incremental cost-effectiveness ratio was 210 USD per injury avoided. Conclusion: The implementation of a SED lancet could eliminate the lancet-related NSIs to zero incidence. The cost increase incurred by the use of SED lancet was tolerable.
Park, Joonseon;Jeon, Chul Hyo;Kim, So Jung;Seo, Ho Seok;Song, Kyo Young;Lee, Han Hong
Journal of Gastric Cancer
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v.21
no.1
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pp.84-92
/
2021
Purpose: To date, no studies have been performed on staging based on the lymph node ratio (LNR) in elderly patients with gastric cancer who may require limited lymph node (LN) dissection due to morbidity and tissue fragility. We aimed to develop a new N staging system using the LNR in elderly patients with gastric cancer. Materials and Methods: The present study included patients aged over 75 years who underwent curative gastrectomy between January 1989 and December 2018. Clinicopathological data including the number of retrieved and metastatic LNs were collected and the LNR values were obtained (LNR = the number of metastatic LNs/the number of retrieved LNs). Eleven LNR groups with intervals of 0.1 were divided into four stages based on the inflection points at which the hazard ratio (HR) increased. Survival analysis was performed to evaluate the prognostic value of the LNR. Results: The four LNR stages included LNR0 (n=364), LNR1 (n=128), LNR2 (n=103), and LNR3 (n=10). In the multivariate analysis, both N staging and LNR staging exhibited significant prognostic values for predicting survival outcomes. However, the incremental change in the hazard ratio (HR) between consecutive stages was greater for the LNR staging than for the N staging (HRs: 1.607, 2.758, and 3.675 for N staging; 1.583, 3.514, and 10.261 for LNR staging). Conclusions: LNR staging is more useful than N staging in predicting the prognosis in elderly patients with gastric cancer and may be used as a complement or alternative to N staging.
Park, Chan-Sol;Kim, Kee-Dong;Han, Taek-Hee;Latif, Abdul;Kim, Doo-Kie
Journal of the Korea institute for structural maintenance and inspection
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v.26
no.6
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pp.222-229
/
2022
The extensive use of external prestressing system with PSC-I beam to strengthen reinforced and prestressed concrete members requires the full understanding of the behavior of the strengthened members. The main approach of this research was to experimentally investigate the flexural performance of the PSC-I beam considering external tendon and an equation was developed which indicated the produced incremental stress in the tendon due to applied load. Further, this equation was verified through performing static loading tests on two experimental specimens considering the presence or absence of external tendon. The test results revealed that, the flexural performance enhanced due to the use of external tendon. Moreover, the magnitude of the estimated flexural strength using proposed stress increasing equation almost coincides with the experimental test results. However, it was the evident of the improvement of the flexural performance of the system by reinforcing with the external tendon and also proved that the proposed equation was valid and effective.
Based on the crucial role of high-speed railway bridges (HSRBs) in the safety of high-speed railway operations, it is an important approach to mitigate earthquake hazards by proceeding with seismic risk assessments in their whole life. Bridge seismic risk assessment, which usually evaluates the seismic performance of bridges from a probabilistic perspective, provides technical support for bridge risk management. The seismic performance of bridges is greatly affected by the degradation of material properties, therefore, material damage plays a nonnegligible role in the seismic risk assessment of the bridge. The effect of material damage is not considered in most current studies on seismic risk analysis of bridges, nevertheless. To fill the gap in this area, in this paper, a nonlinear dynamic time-history analysis has been carried out by establishing OpenSees finite element model, and a seismic vulnerability analysis is carried out based on the incremental dynamic analysis (IDA) method. On this basis, combined with the site risk analysis, the time-dependent seismic risk analysis of an offshore three-span HSRB in the whole life cycle has been conducted. The results showed that the seismic risk probabilities of both components and system of the bridge increase with the service time, and their seismic risk probabilities increase significantly in the last service period due to the degradation of the material strength, which demonstrates that the impact of durability damage should be considered when evaluating the seismic performance of bridges in the design and service period.
Hazem W. Tawadros;Mousa M. Farag;Sameh S.F. Mehanny
Earthquakes and Structures
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v.24
no.4
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pp.289-301
/
2023
Developing a competent soil-bridge interaction model for the seismic analysis of piled foundation bridges is of utmost importance for investigating the seismic response and assessing fragility of these lifeline structures. To this end, ground motion histories are deemed necessary at various depths along the piles supporting the bridge. This may be effectively accomplished through time history analysis of a free-field standalone soil column extending from bedrock level to ground surface subjected to an input bedrock motion at its base. A one-dimensional site/ground response analysis (vide one-directional shear wave propagation through the soil column) is hence conducted in the present research accounting for the nonlinear hysteretic behavior of the soil stratum encompassing the bridge piled foundation. Two homogeneous soil profiles atop of bedrock have been considered for comparison purposes, namely, loose and dense sand. Analysis of the standalone soil column has been performed under a set of ten selected actual bedrock ground motions adopting a nonlinear time domain approach in an incremental dynamic analysis framework. Amplified retrieved PGA and maximum soil shear strains have been generally observed at various depths of the soil column when moving away from bedrock towards ground surface especially at large hazards associated with high (input) PGA values assigned at bedrock. This has been accompanied, however, by some attenuation of the amplified PGA values at shallower depths and at ground surface especially for the loose sand soil and particularly for cases with higher seismic hazards associated with large scaling factors of bedrock records.
Key questions to researchers interested in nonlinear analysis of skeletal structures are whether the distributed plasticity approach - albeit computationally demanding - is more reliable than the concentrated plasticity to adequately capture the extent and severity of the inelastic response, and whether force-based formulation is more efficient than displacement-based formulation without compromising accuracy. The present research focusing on performance-based seismic response of mid-span concrete bridges provides a pilot holistic investigation opting for some hands-on answers. OpenSees software is considered adopting different modeling techniques, viz. distributed plasticity (through either displacement-based or force-based elements) and concentrated plasticity via beam-with-hinges elements. The pros and cons of each are discussed based on nonlinear pushover analysis results, and fragility curves generated for various performance levels relying on incremental dynamic analyses under real earthquake records. Among prime conclusions, distributed plasticity modeling albeit inherently not relying on prior knowledge of plastic hinge length still somewhat depends on such information to ensure accurate results. For instance, displacement-based and force-based approaches secure optimal accuracy when dividing, for the former, the member into sub-elements, and satisfying, for the latter, a distance between any two consecutive integration points, close to the expected plastic hinge length. On the other hand, using beam-with-hinges elements is computationally more efficient relative to the distributed plasticity, yet with acceptable accuracy provided the user has prior reasonable estimate of the anticipated plastic hinge length. Furthermore, when intrusive performance levels (viz. life safety or collapse) are of concern, concentrated plasticity via beam-with-hinges ensures conservative predicted capacity of investigated bridge systems.
Distribution channel decisions involve long-term commitments with other firms that are very difficult to change or replace. In particular, marketing channel decisions in emerging markets are much more complicated due to unfamiliar conditions and problems such as lack of market data and distribution systems. Therefore, when a company considers changing or introducing a marketing channel in an area, it is much more difficult to judge its effectiveness in an emerging market than in a developed market. In this study, we investigate the development process of a new direct marketing channel of Hongfu Fertilizer Company (hereafter Hongfu), a medium-sized Chinese fertilizer manufacturer, and propose an approach to test the feasibility of this new marketing channel in the Chinese rural market. We measure the effectiveness of Hongfu's new marketing channel from two perspectives: i) from customers' perspective through direct responses of farmers, which showed that a new channel can increase the convenience and lower the purchasing costs for the farmers, and ii) from the company's perspective, by calculating the incremental profit of the company using the expansion factor (T/Q) method, which suggested that the execution of Hongfu's strategy to expand a new marketing channel will result in an increase in profits. The results of this study contribute to the development of a methodology to test the feasibility of a new direct marketing channel in the emerging markets such as the Chinese rural market. Traditional and indirect distribution channels in emerging markets are generally not very efficient and difficult to change. Especially, in emerging markets, like the Chinese rural market, the methods of testing channel feasibility must be different from that of developed markets. Considering market situations, market experiments can be more effective then systematic market surveys in testing channel feasibility in emerging markets. This study implies that managers must learn to cope with a transition from the traditional marketing channels in emerging markets. With the development in farmers' understanding of marketing concept, the transition from traditional marketing channel is unavoidable for all firms. Farmers in China are generally very conservative, however, their buying behaviors are changing. Therefore, fertilizer companies should try to adjust in accordance with farmers' demand characteristics that the efforts to meet the economic needs of farmers with new marketing channels as well as trust building are critical in the near future.
Herian A. Leyva;Eden Bojorquez;Juan Bojorquez;Alfredo Reyes;Fabrizio Mollaioli;Omar Payan;Leonardo Palemon;Manual A. Barraza
Structural Engineering and Mechanics
/
v.90
no.3
/
pp.313-323
/
2024
Most of existing buildings in Mexico City are made of reinforced concrete (RC), however, it has been shown that they are very susceptible to narrow-band long duration ground motions. In recent years, the use of dual systems composed by Buckling Restrained Braces (BRB) has increased due to its high energy dissipation capacity under reversible cyclical loads. Therefore, in this work the behavior of RC buildings with BRB is studied in order to know their performance, specifically, the energy distribution through height and response transformation factors between the RC and simplified systems are estimated. For this propose, seven RC buildings with different heights were designed according to the Mexico City Seismic Design Provisions (MCSDP), in addition, equivalent single degree of freedom (SDOF) systems were obtained. Incremental dynamic analyses on the buildings under 30 narrow-band ground motions in order to compute the relationship between normalized hysteretic energy, maximum inter-story drift and roof displacement demands were performed. The results shown that the entire structural frames participate in energy dissipation and their distribution is independent of the global ductility. The results let propose energy distribution equations through height. Finally, response transformation factors between the SDOF and multi degree of freedom (MDOF) systems were developed aimed to propose a new energy-based approach of BRB reinforced concrete buildings.
Purpose - The purpose of this study was to analyse the relationship between R&D tax support policy and firm innovation activity using data on firms engaged in 12 national strategic technology sectors. Design/methodology/approach - This study collected survey data from 664 companies engaged in national strategic technologies. The data were then analysed using the Propensity Score Matching (PSM) analysis. Findings - First, corporate R&D tax support had a statistically significant positive (+) relationship with firm innovation performance. Second, there was a statistically significant positive (+) relationship with incremental innovation, but there was no statistical significance with radical innovation. Third, there was a statistically significant positive (+) relationship with the firm's first innovation, but there was no statistical significance with the world's first innovation. Fourth, there was a statistically significant positive (+) relationship with the number of R&D projects of a firm. Finally, there was a statistically significant positive (+) relationship with a firm's open innovation. Research implications or Originality - First, in terms of policy effectiveness, the government needs to consider promoting R&D tax support policies in areas where R&D competition is fierce. For private companies engaged in the 12 national strategic technology fields, the R&D tax support policy is working in the direction of promoting corporate innovation activities, and this positive policy effect is likely to be effective in areas where R&D competition is fierce. Second, if the government wants to improve the quality of corporate innovation activities through R&D tax support policies, it needs to provide incentives higher than the current level.
National Innovative Capability (NIC) is an important decisive factor where economic growth is concerned. As such, it is very important to measure and manage NIC. The composite index approach is one of the widely used approaches to measuring NIC, but there have been insufficient reviews of its feasibility and reliability. This paper conducted an analysis of the feasibility and reliability of the report on the last three years (i.e. 2011 through 2013) of the Innovation Union Scoreboard (IUS) of the EU, which is the most representative means of measuring NIC. It turned out that its reliability meets the recommended criteria as a result of Chronbach's alpha-based test of the models of IUS-related composite index. However, neither the absolute fit index nor the incremental fit index was found to meet the recommended criteria in a construct validity analysis. It also turned out that predictive validity is very low as a result of panel linear regression analysis of sectors and items of IUS-related composite index. This paper presents a number of considerations to be made when measuring national innovative capability using the composite index approach, as well as major policy suggestions based on the results of the analysis.
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