• Korean Journal of Clinical Pharmacy
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• v.29 no.3
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• pp.147-155
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• 2019

Objectives: The purpose of this study was to investigate the association between fracture risk and proton pump inhibitor (PPI) use to establish evidence for defining high-risk groups of fracture among PPI users. Methods: A case-control study was performed using the National Health Insurance Sample Cohort Database from January 2002 to December 2013. The cases included all incidences of major fractures identified from January 2011 to December 2013, and up to four controls were matched to each case by age, gender, osteoporosis, and Charlson comorbidity index. Conditional logistic regression was used to calculate the adjusted odds ratio (aOR) and associated 95% confidence interval (CI). Results: Overall, 14,295 cases were identified, and 63,435 controls were matched to the cases. The aOR of fractures related to the use of PPIs was 1.06 (95% CI: 1.01-1.11). There was a statistically significant association between fracture and PPI use within 3 months of the last dose, and a trend of increasing fracture risk with increasing cumulative PPI dose. The risk of fracture was significantly higher in patients who took PPIs for more than 1 year during the 2-year observation period. Conclusion: Patients who have been using PPIs for more than 1 year should be warned about the risk of fracture during or at least 3 months after discontinuing the PPI.

• Journal of The Korean Society of Integrative Medicine
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• v.9 no.4
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• pp.19-28
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• 2021

Purpose : The purpose of this study was to apply manual lymphatic drainage (MLD) and high-frequency diathermy (HFD) to patients with axillary web syndrome (AWS), one of the side effects of breast cancer surgery, and to treat upper extremity pain, volume, function of the upper extremity, (joint range of motion; ROM, disabilities of the arm, shoulder and hand; DASH) and quality of life before and after treatment. It is to determine the effect of treatment by checking the level change. Methods : This study is a case series. A total of 5 patients diagnosed with AWS after breast cancer surgery voluntarily participated in this study. The intervention program consisted of stretching, MLD and HFD. It was conducted 3 times a week for 30 minutes for 4 weeks. In order to compare the effects of pain (numeric pain rating scale; NPRS), volume, upper limb function (ROM, DASH) and quality of life (the European organization for research and treatment of cancer quality of life questionnaire-breast, EORTC QLQ-BR23) evaluations were compared before and after 4 weeks of intervention. All measured variables were analyzed and expressed as mean, standard deviation and percentage. Results : The shoulder NPRS level of the subjects in all case groups decreased, the volume decreased and the shoulder flexion, abduction ROM increased. It showed improvement in DASH and quality of life, QLQ-BR23. Conclusion : After breast cancer surgery, we confirmed the possibility that MLD and HFD treatments could be effective in improving pain, decreasing volume, increasing upper extremity function, and quality of life for patients who have difficulties with AWS. The possibility has been confirmed, and additional research is needed by increasing the number of participants in the experiment in the future.

• Journal of the Korean GEO-environmental Society
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• v.12 no.9
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• pp.5-11
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• 2011

Recently, large and deep excavations are increasing. The damage of adjacent structures due to excavation has steadily increased with increasing construction demand. Especially in urban development and poor conditions, the excavation adjacent to the subway structures has caused a lot of problems. This paper was reviewed that the underground excavation and reinforcement of the status process through a case study on the field. And stability analysis through the case study evaluates applicability for reasonable reinforcement method by numerical analysis. As a result, the strata distribution condition of all 16 sites consisted of landfill from the top and distributed in the order of deposits, weathered soils, weak rock from the bottom. Also, when proceeding the excavation adjacent to structures, the location of site and layer conditions have highly effect on the results of the construction. Therefore, this study was applied reinforcement method to protect damage by excavation. Displacement and settlement were within allowable criterion and hence, stability of structure was analyzed as safe.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.42 no.1
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• pp.135-144
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• 2022

This paper aimed to analyze the type of urban shrinkage over the past 20 years for four case cities designated as abandoned mining area promotion zones and present the direction of future urban spatial policies through the analysis of shrinking status. According to the analysis of urban shrinkage in the past 20 years, all of the case cities were analyzed as fixed-type shrinking cities, showing a population decrease of more than 30% over the past 40 years compared to the peak population. Despite the decrease in population, the designated area of urbanization and non-urban areas is increasing every year, and the development permit and construction permit in non-urban areas are also increasing, requiring efficient management and operation of urban space. It is necessary to study military-level cities in the high-risk phase of extinction in the future, and to develop various indicators for segmentation of urban shrinkage types and analysis of status by type.

• Proceedings of the Korean Society of Crop Science Conference
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• 2022.10a
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• pp.109-109
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• 2022

The global population is increasing every year, and the amount of food waste is also increasing. Direct landfilling of food waste has been prohibited since 2005, and in accordance with the London Convention in 2013, the discharge of livestock manure, sewage sludge, and food waste into the sea is prohibited. In the case of incineration to treat the discharged food waste, the heat point is lowered due to the moisture in the food waste itself, so fuel must be added. Therefore, this study was conducted to get basic data for setting the limit of application by investigating the growth and yield of crops after treating food waste dry powder mixed fertilizer (MF) on red pepper. In the experiment, continuous cultivation was carried out for two years in 2021 (1st year) and 2022 (2nd year). The treatment groups were set as Not Treatment (NT), Chemical Fertilizer (CF), Mixed Fertilizer (MF), Mixed Fertilizer×2 (MF×2). After harvest, crop growth and yield were investigated. As a result of the 1st years of growth survey, CF, MF, MF×2 show significant difference in shoot length compared to NT. About fresh weight and dry weight, CF show significant difference compared to NT. The 2nd years of growth survey, the shoot and root length, fresh weight did not show significant difference with NT. In case of dry weight, MF is significant increased compared to NT. As a result of the yield survey of the 1st year, all treatment groups did not show a significance in yield compared to the NT. In case of 2nd year, all treatment groups show significantly increased value compared to NT. The yield of MF was highest among the treatment groups. In the future, it is thought that it is necessary to quantitatively evaluate the effect of food waste dry powder mixed fertilizer through additional experiments and continuous cultivation, and to establish an appropriate amount of use and establishment of a manual based on this.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.36 no.2
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• pp.73-88
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• 2000

A series of analysis and experiment on the fishing gear and method of the existing midwater pair trawl net with 12,800mm of maximum mesh size is carried out to determine the most effective shape factor. As the first step of this study, the fishing gear and method for the existing net are analyzed to solve problems, such as being low of the net height by increasing the towing speed, twist of net pendant and twine, suspension of float between knots of mesh. etc. Standing on these results, the existing net are modified by very effective shape based on the theory and technology designing the fishing gear. Also, the model experiment is carried out to determine the most effective shape factor of the modified net in the circulation water channel. The obtained results can be summarized as follows : 1. On the length of net pendants(No.2 and No.3) connected with side line, opening efficiency of net with length 8.0cm of net pendant is the greatest and in the order of 11.5cm, 15.0cm. 2. On the number of the net pendant, opening efficiency of net with 4 lines of net pendant is the greatest and in the order of 3 lines, 2 lines. Center part of side panel is pushed out backward, and the pushed length is increasing by increasing flow speed. 3. On the sinking force, opening efficiency of the net is increasing by increasing sinking force. And opening efficiency shows almost the same when sinking force is greater about 1.5 times than that of the existing net in case of the net with 3 lines of net pendant, and about 1.6 ~ 1.7 times than that of the existing net in case of the net with 2 lines.

• Journal of Physiology & Pathology in Korean Medicine
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• v.23 no.6
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• pp.1470-1479
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• 2009

The purpose of this study was to investigate the relationship of Dampness-phlegm to blood lipid level and second reason of hyperlipidemia in acute stroke patients by case-control study. This study was done over 348 patients hospitalized in the Oriental Medical Hospital of Daejeon University of November 2006 to July 2008. Patients had been interviewed by residents and medical specialists who studied standard operation procedures in Fundamental Study for Syndrome of Oriental Medicine for Stroke. Study subjects consisted of 86 patients who distributed to Dampness-phlegm by medical specialist and discriminating program as the case I group, 157 patients who distributed to Dampness-phlegm by medical specialist or discriminating program as the case II group and 191 patients who distributed to Non-Dampness-phlegm by medical specialist and discriminating program as the control group. For the purpose of obtaining suitable result we analyzed blood lipid level of each group by univariate and multivariate logistic analysis. Dampness-phlegm was not significant correlated with increasing of Total cholesterol, Triglyceride and decreasing of HDL cholesterol. Dampness-phlegm was significant correlated with increasing LDL cholesterol and the independent predictors of hyperlipoproteinemia by multivariate logistic analysis. Dampness-phlegm was not significant correlated with diabetes melitus, liver disease, kidney disease, obesity and abdominal obesity. In this study, we demonstrated new relationship between Dampness-phlegm and LDL cholesterol. Based on these results, it is suggested that Dampness-phlegm would be the independent predictors of hyperlipoproteinemia. And more prospective studies are to be done with more clinical data.

• Korean Journal of Poultry Science
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• v.17 no.4
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• pp.318-326
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• 1990

This experiment was conducted to determine the economic housing density levels on caged laying hens The experiment was carried out with 600 ISA Babcock strain of white coder and 450 ISA Brown strain of brown color for production period(21－72 weeks) from May 11. 1987 to June 27. 1988. The levels of housing density was employed 5 or 6 by hen's color from 272 to 920$\textrm{cm}^2$/per hen. The results obtained were summarzed as follows ： 1. Although there were not statistically significant among the housing density levels, The body weight gain for pullet period(14－20 weeks) were in case of white pullet the lowest at the group of high crowding density (272$\textrm{cm}^2$/per pullet) and in case of Brown pullet was the lowest at the group of high crowding density(306$\textrm{cm}^2$/per pullet). 2. Viabillity of pullet from 14 to 20 weeks were more 97% and there urere not statistically significant among the housing density. 3. Viabillity of laying hens was increased as increasing housing density through the etire product period(21－72 weeks) but 453$\textrm{cm}^2$/per hen group(in case of brown hen) showed a significant difference (P＜.05). 4. Rate of egg production through the etire production period(21－72 weeks) were significantly increased by increasing housing density (P＜.05 or .01). 5. Average egg weight through the entire production period(21－72 weeks) was not significantly different among housing density levels at all laying kent 6. In case of white strain, egg mass per hen among treatment during the age of 63－72 weeks were decreased by increasing housing density, meanwhile, in case of brown strain were increased by decreasing housing density during the whole period and there were significant different among the all treatment 7. There were no significant different in feed intake among the all treatment through the entire production period(21－72 weeks) at the white strain laying hens but in case of brown strains, Feed intake were increased by increasing housing density and feeding spece/per hen, and there were significant different among the all treatment 8. Feed requirements per egg at white strain was the highest when the 272$\textrm{cm}^2$/per hen levels and at the brown strains was the highest when the 306$\textrm{cm}^2$/per hen levels, however, among the other treatment were no significant.

• Journal of Intelligence and Information Systems
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• v.9 no.1
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• pp.23-51
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• 2003

With the recent expansion of internet shopping mall, the importance of intelligent products recommendation agents has been increasing. for the products recommendation, This paper propose case-based reasoning approach, and developed a case-based bundle products recommendation system which can recommend a set of sea food used in family events. To apply CBR approach to the bundle products recommendation, it requires the following 4R steps : \circled1 Retrieval, \circled2 Reuse, \circled3 Revise, \circled4 Retain. To retrieve similar cases from the case-base efficiently, case representation scheme is most important. This paper used OW(Object Modeling Technique) to represent bundle products recommendation cases, and developed a similarity measure method to search similar cases. To measure similarity, we used weight-sum approach basically. Especially This paper propose the meaning and uses of taxonomies for representing case features.

• Proceedings of the KAIS Fall Conference
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• 2003.11a
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• pp.185-190
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• 2003

Due to the rapid growth of Internet, means of communication with customers in a traditional customer support environment such as telephone calls are being replaced by mainly e-mail in a Web-based customer support system. Although such a Web-based support is efficient and promises potential benefits for firms, including reduced transaction costs, reduced time, and high quality of support, there are some difficulties associated with responding to many types of customer’s inbound e-mails appropriately .As many types of e-mail are received, considerable attention is being paid to methods for increasing the efficiency of managing and responding e-mails. This research proposes an intelligent system for managing customer’s inbound e-mails in organizations by applying case based reasoning technique for responding to various customers' inbound e-mails more effectively. In this approach, a case is represented as a frame-typed data structure corresponding to an inbound e-mail, keywords, and its reply e-mail. In the retrieval procedure, keywords and affinity set is developed to index a case, and then the case is represented as a vector, a case vector. Also, cosines value is calculated to measure the similarity between a new inbound e-mail and the cases in the case base. In the adaptation procedure, we provide several adaptation strategies to adapt and modify the retrieved case. The strategies guide to make an outbound e-mail using product databases, databases for customer support, etc. Additionally, the Web-based system architecture is proposed to implement our methodology. The proposed methodology and system will be helpful for developing more efficient Web-based customer support.