• Physical Therapy Korea
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• v.19 no.2
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• pp.59-68
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• 2012

This meta-analysis investigated the effects on arm motor impairment, arm motor function and disability, and psychological aspects of constraint-induced movement therapy (CIMT) for upper extremity hemiparesis following stroke, based on Korean studies. A comprehensive search of the complete Korean studies information service system (KISS), Research Information Sharing Service (RISS), Korea National Library, and the Korean Medical Database to September 2011 was conducted. Eleven eligible controlled clinical trials compared CIMT to a control group or an alternative treatment. All outcome measures of arm motor impairment, arm motor function and disability, and psychological aspects were pooled for calculating effect size. The overall effect size of CIMT was .700 (95% confidence interval=.482~.918). The CIMT programs showed large effect on the aspect of arm motor function and disability (the effect size is .920) and the psychological aspect (the effect size is .946). The effect of CIMT on arm motor impairment was moderate (the effect size is .588). These results show that CIMT may improve upper extremity motor impairment, function and disability, and psychological aspects following stroke. However, these results were based on a small number of studies, and not all of them were randomized control trials. Additional research is needed to include larger well-designed trials to resolve these uncertainties.

• Journal of Biomedical Engineering Research
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• v.35 no.3
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• pp.68-74
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• 2014

Recent research on mild cognitive impairment (MCI) has shown that cognitive and memory decline in this disease is accompanied by disruptive changes in the brain functional network. However, there have been no graph-theoretical studies using $^{11}C$-PIB PET data of the Alzheimer's Disease or mild cognitive impairment. In this study, we acquired $^{18}F$-FDG PET and $^{11}C$-PIB PET images of twenty-four normal aging control participants and thirty individuals with MCI from ADNI (Alzheimer's Disease Neuroimaging Initiative) database. Brain networks were constructed by thresholding binary correlation matrices using graph theoretical approaches. Both normal control and MCI group showed small-world property in $^{11}C$-PIB PET images as well as $^{18}F$-FDG PET images. $^{11}C$-PIB PET images showed significant difference between NC (normal control) and MCI over large range of sparsity values. This result will enable us to further analyze the brain using established graph-theoretical approaches for $^{11}C$-PIB PET images.

• The Journal of Asian Finance, Economics and Business
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• v.7 no.8
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• pp.747-752
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• 2020

This study examines cognitive impairment, which is one of the results from social exclusion and leads to logical reasoning disorders. This study also investigate how cognitive errors called abductive inference error occur due to cognitive impairment. Present study was performed with 81 college students. Participants were randomly assigned to the group who has experienced social exclusion or to the group who has not experience the social exclusion. We analyzed how the degree of error of abductive inference differs according to the social exclusion experience. The group who has experienced social exclusion showed a higher level of abductive inference error than the group who has not experience. The abductive condition inference value of the group who has experienced social exclusion was higher in the group with the deduction condition inference value of 90% than in the group with the deduction condition inference value of 10%, and the difference was also significant. This study extended the concepts of cognitive impairments, escape theory, cognitive narrowing which are used to explain addiction behavior to human cognitive bias. Also this study confirmed that social exclusion experience increased cognitive impairment and abductive inference error. Future research directions and implications were discussed and suggested.

• The Journal of Korea Robotics Society
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• v.11 no.2
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• pp.41-50
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• 2016

This paper describes the effect of a robot cognitive rehabilitation program on cognitive functions for the elderly with mild cognitive impairment, and compares it with traditional cognitive therapy programs. Three experiment groups including cognition therapy group, robot cognitive rehabilitation group, and hybrid group have been sampled and one comparative group has been organized for this research. 32 old people whose ages are between 61 and 88 with mild cognitive impairment participated in the programs with an admission of W care hospital. According to the program results, the cognitive therapy program alone had shown a positive effect on the attention function, and the robot cognitive rehabilitation program alone had a positive effect on the total intelligence and memory function. However, a simultaneous operation with both programs had shown a positive effect on the three intelligence areas such as total, basic, and management quotients as well as attention and memory functions as subsidiary factors. This paper has verified that the proposed robot cognitive rehabilitation program makes a positive effect on a cognitive function and plays a complementary role with traditional cognitive therapy programs.

• Journal of Korean Public Health Nursing
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• v.33 no.2
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• pp.242-257
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• 2019

Purpose: This study examined the life experiences of the wives of men who were born with normal vision but gradually developed a visual impairment, with particular focus on their way of facing and coping with their life crisis. Method: A narrative approach was used to not only understand women's experiences within sociocultural contexts, but also reveal the subjective meaning of their personal life stories through their own voices. A purposive sample of three participants having husbands unexpectedly diagnosed with visual impairment during their marriage was recruited. The data were analyzed using the narrative analysis methods suggested by Clandinin and Connelly. Results: The wives took the crisis of their husbands' visual impairment as an economic crisis of the family. They faced a variety of difficulties, including extreme despair, role changes, and economic burdens. On the other hand, they tried to keep the family secure through a range of coping strategies that were motivated by compassion toward the husbands, maternal affection for the children, and a sense of responsibility for their families. Conclusion: This study revealed the need for financial support for temporarily disadvantaged families. In addition, various nursing and counseling programs for the family members will also be needed to help recover the family functions.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2009.05a
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• pp.191-194
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• 2009

Vocational rehabilitation is defined as a process which helps people with disabilities to maintain life of non-disabled people and vocational assessment is a part of it. Traditionally, vocational assessment is performed through using of assessment tools, vocational counseling and so on. It is very efficient to apply vocational assessment to people with disabilities using the internet, but we should provide them with web accessibility. In this paper, we design and implement the aptitude test system for people with visual impairment supporting web accessibility. We develop the aptitude test system using the Holland Test which is the assessment tool of career guidance and counseling. We also show that the aptitude test system for people with visual impairment supports web accessibility more than previous Holland Test which is served in the internet.

• Asia-Pacific Journal of Business
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• v.10 no.4
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• pp.65-75
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• 2019

We point out the limitations of Bloomberg Adjustment beta, shows that long-term beta does not converge with 1 and suggests an alternative to using proxy beta as beta's long-term forecast. We analyze whether the beta produced in the manner proposed by Bloomberg beta or proxy beta meets the purpose of calculating capital costs, for example, for the evaluation of corporate value. In particular, We apply in impairment valuations of assets and some analysis of how it affects. The proposal of the article applied in cases of analysis results are as follows : First, unlike the Bloomberg approach, long-term beta does not converge with market beta and therefore is not suitable as market forecast by beta. Second, estimating the suggested proxy beta as beta's predictive value resulted in Bloomberg beta and other adjustment Beta in the case categories, and the gap was large. Third, applying proxy beta results in a more appropriate valuation of the impairment loss on assets.

• Physical Therapy Rehabilitation Science
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• v.11 no.2
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• pp.154-164
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• 2022

Objective: The purpose of this study is to select a cognitive training game that can evaluate five cognitive domains and to study their validity with existing cognitive evaluation tools. Design: Methods: Delphi survey was conducted through the 2nd questionnaire for 30 experts to select games suitable for training 5 cognitive domains. Five cognitive training games and Mini Mental State Examination - Korea(MMSE-K), and cognitive impairment screening test(CIST) were conducted for 82 elderly in the community. Pearson correlation analysis was performed to find out the correlation of the three tests. The ROC curve was used to calculate the selection criteria for the game results for the screening evaluation of the presence or absence of mild cognitive impairment. Results: The coefficient of variation to evaluate the stability of the Delphi survey was less than 0.50 in most game items. The 'correct answers' and 'level' of the five final selected game items showed a statistically significant positive correlation with the CIST and MMSE-K scores. CIST score and 'time' of all game items except 'number making_time' showed a statistically significant negative correlation. Conclusions: The validity of the cognitive training program using smart devices was evaluated, and the criteria for classifying the cognitive domain and distinguishing the presence or absence of cognitive impairment were confirmed.

• The Korean Journal of Physiology and Pharmacology
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• v.26 no.6
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• pp.415-425
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• 2022

Memory formation in the hippocampus is formed and maintained by circadian clock genes during sleep. Sleep deprivation (SD) can lead to memory impairment and neuroinflammation, and there remains no effective pharmacological treatment for these effects. Myricetin (MYR) is a common natural flavonoid that has various pharmacological activities. In this study, we investigated the effects of MYR on memory impairment, neuroinflammation, and neurotrophic factors in sleep-deprived rats. We analyzed SD-induced cognitive and spatial memory, as well as pro-inflammatory cytokine levels during SD. SD model rats were intraperitoneally injected with 10 and 20 mg/kg/day MYR for 14 days. MYR administration significantly ameliorated SD-induced cognitive and spatial memory deficits; it also attenuated the SD-induced inflammatory response associated with nuclear factor kappa B activation in the hippocampus. In addition, MYR enhanced the mRNA expression of brain-derived neurotropic factor (BDNF) in the hippocampus. Our results showed that MYR improved memory impairment by means of anti-inflammatory activity and appropriate regulation of BDNF expression. Our findings suggest that MYR is a potential functional ingredient that protects cognitive function from SD.

• Physical Therapy Rehabilitation Science
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• v.11 no.3
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• pp.304-310
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• 2022

Objective: Mild cognitive impairment (MCI) is a condition in which cognitive and executive functions are reduced, and older adults with MCI are ten times more likely to develop dementia than healthy older adults. Expression of brain-derived neurotrophic factor (BDNF) through aerobic exercise is associated with increased cognitive and executive functions. in this review, randomized controlled trials (RCTs) on the effects of aerobic exercise on BDNF in individuals with mild cognitive impairment are summarized and qualitatively and quantitatively analyzed to suggest the necessity of aerobic exercise. Design: a systematic review and meta-analysis. Methods: RCTs were searched for changes in BDNF through aerobic exercise using four international databases. Quality assessment and quantitative analysis were performed using RevMan 5.4. Quantitative analysis was quantified with a standardized mean difference (SMD) and presented as a random effect model. Results: Three RCTs evaluated BDNF in 123 patients with MCI. There was a significant improvement in the experimental group that performed aerobic exercise compared to the control group. The results analyzed using the random effects model were SMD = 0.48. Conclusions: In this review, we reported the effects and mechanisms of aerobic exercise in individuals with MCI. As a result of synthesizing RCTs that performed aerobic exercise, a significant increase in BDNF was confirmed.