• CELLMED
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• v.10 no.2
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• pp.17.1-17.5
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• 2020

Background: Chronic kidney disease (CKD) is affective a large portion of the world population prompting the need for extensive healthcare resources such as lifelong dialysis or kidney transplantation. The beneficial effect of conventional therapy in controlling the CKD progression remains a challenge due to their relative efficacy, safety, and accessibility. On the other hand, Unani medicine provides a therapeutic regimen that consists of a combination of treatment from rehabilitation to herbal pharmacotherapy. Methods: Two cases of chronic kidney disease were treated with dietotherapy, regimenal therapy ('bukhoor aam') and oral herbal drugs for 2-3 weeks. Endpoints of evaluation were symptoms and signs of the CKD, kidney function test, urine albumin, urine RBC, hemoglobin and liver function test. Result: Notable improvement was observed in the endpoints. Conclusion: Unani treatment was observed preliminarily beneficial in the treatment of chronic kidney disease. Rigorous pharmacological and clinical studies should be performed to warrant their efficacy and safety in CKD individuals.

• CELLMED
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• v.7 no.4
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• pp.16.1-16.2
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• 2017

Doronicum Hookeri of family Asteraceae is an important medicinal drug distributed in Himalayas at Lachen and Tungu, Sikkim, Nepal, Bhutan, Tibet between 12,000 to 14,000 ft. Its roots are widely used as folk medicine and are commonly known as "Darunaj-aqrabi" in Unani and as "Leopard's bane" in English. Roots are traditionally used as a constituent of, act as a stomachic and dissolves trapped gases. Antibacterial and antifungal activities of D. hookeri roots have been previously reported. The methanolic extract of root part possessed higher phenolic content and thus higher free radical scavenging and reducing activities. The methanolic extract of this plant showed scavenging and antioxidant activities in DPPH (2,2- diphenyl-1-picryhydrazy) radical scavenging assay.