• Journal of Korean Academy of Nursing
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• v.4 no.1
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• pp.121-134
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• 1974

This study is an attempt to evaluate the use of an oral contraceptive by: 1. Deforming the acceptance rate of the oral contraceptive according to socio-demographic characteristics 5. Estimating the duration of the use of the contraceptive f. Discovering reasons why the contraceptive was discontinued 4. Computing the cumulative continuation and discontinuation rate according to socio-demographic characteristics, history of pregnancies, and attitude of husband at the time of selection of the contraceptive. One hundred sixty-eight women of child bearing age (14-49 years), residing in Yonhee Dong, Seoul, Korea and registered as oral contraceptive accepters at Yonsei Community Health Center, were interviewed during a three week period in 1973. The questionnaire was designed to determine the socio-demographic characteristics of the oral contraceptive accepters, the current status of their family planning practice, medical reactions if any, discontinuation practice, and the duration of the use of the contraceptive. The major findings of the study were as follows; 1. The acceptance rate was highest for women between 30 and 34 years of age, the mean age being 34.4 years. 2. Fifty six point five percent of all respondents said that thirty years of age was the ideal age to stop having children. 3. The average number of living children was 3.5 and fifty four point eight percent of respondents felt 2 boys and I girl was the ideal number of children. 4. The average number of pregnancies was 5.2 and the average number of induced abortion was I. 4. 5. Fifty eight point eight percent of the respondents had experience in the use of contraceptive methods in the past. 6. Forty one point seven percent of the respondents replied that they chose the oral contraceptive because, "it was not complicated to use." 7. Sixty four point eight percent of the women said their husband approved of their taking the pill. 8. The cumulative discontinuation rate was sixty point five percent of the total respondents for one year in first segment. 9. Sixty six point nine percent of the respondents had experienced side-effect while using the pill. The side effects for 68.9 percent of these women were castro-intestinal upsets. Twenty point eight percent of the women who had side effects consulted with medical personnel about them. Women who had more education had more side effects. 10. Seventy three point two percent of the women who discontinued the pill did so because of medical reasons. Women who were younger discontinued the pill for personal reasons more-often than older women. Among personal reasons listed for discontinuing the pill was the attitude of the husband. 11. The average duration of continuance of the contraceptive was 5.3 cycles under 29 years of age; 7.4 cycles between 30 and 34 years of age; and 8.4 cycles over 40 years of age. 12. The discontinuation rate was seem to increase sharply in the early cycle and increase more slowly in later cycle. Conclusions and suggestions: Since the attitude of the husband was shown to be important, the current family planning program should be expended to include approach to husband. For women who must use the oral contraceptive, education and support must be enhanced so that the discontinuation rate due to side effects will be decreased.

• Journal of Korean Tunnelling and Underground Space Association
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• v.12 no.5
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• pp.399-405
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• 2010

The accumulated displacements and fatigues of rock are increased by the stress-hysteresis, induced from repeated frost-thawing. Also the shear strength is decreased by them continuously. The stress-hysteresis is affected by the atmospheric temperature changes, whose behavior is visco-elasticity, usually. Therefore, to do ideal body analysis, Kelvin model could be used to analyze the frost-thawing behavior in winter. In general, rock slope failure occurs by the deterioration of rocks, which is caused by the repetition of freezing-thawing process. In order to keep the safety of such rock mass structures the deterioration process of rock needs to be described quantitatively using some meaningful parameters. In this work, the deterioration process in freezing-thawing cycle of tuff, which is a famous soft porous rock, is investigated through laboratory tests and successfully described as a differential equation for the change of porosity. And then, the deterioration of the mechanical properties of rock, such as Young's modulus and uniaxial compressive strength, are quantitatively described as a function of the porosity.

• Tunnel and Underground Space
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• v.11 no.2
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• pp.132-145
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• 2001

The purpose and need of the study is to quantify the advantage or disadvantage of the environmental friendliness of the partitioning of nuclear fuel cycle. To this end, a preliminary study on the quantitative effect of the partition on the permanent disposal of spent PWR and CANDU fuel (HLW) was carried out. Before any analysis, the so-called reference radionuclide release scenario from a potential repository embedded into a crystalline rock was developed. Firstly, the feature, event and processes (FEPs) which lead to the release of nuclides from waste disposed of in a repository and the transport to and through the biosphere were identified. Based on the selected FEPs, the ‘Well Scenario’which might be the worst case scenario was set up. For the given scenario, annual individual doses to a local resident exposed to radioactive hazard were estimated and compared to that from direct disposal. Even though partitioning and transmutation could be an ideal solution to reduce the inventory which eventually decreases the release time as well as the peaks in the annual dose and also minimize the repository area through the proper handling of nuclides, it should overcome major disadvantages such as echnical issues on the partitioning and transmutation system, cost, and public acceptance, and environment friendly issues. In this regard, some relevant issues are also discussed to show the direction for further studies.

• BMB Reports
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• v.39 no.6
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• pp.722-729
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• 2006

Recently, we have reported that 3-hydrogenkwadaphnin (3-HK), a diterpene ester isolated from Dendrostellera lessertii (Thymealeaceae), is very effective against leukemia cell lines without any detectable effects on normal cells (Moosavi et al., 2005b). In this study, we report that 3-HK induces $G_1$ cell-cycle arrest, differentiation and apoptosis in APL NB4 cell line. Indeed, the drug between 24 to 96 h induced 7-65% growth inhibition of NB4 cells. Cell viability was also decreased by 2-55% between 24 to 96 h treatments with the drug, respectively. These effects of the drug were also dose-dependent. According to flow cytomtry results, 3-HK (15 nM) induced a significant G1-arrest up to 24 h which was consequently followed with appearance of sub-$G_1$ peak at 72 to 96 h. Hoechst 33258 staining and DNA fragmentation assays confirmed the occurrence of apoptosis among the treated cells. On the other hand, NBT reducing assay, Wright-Giemsa staining, phagocytic activity and expression of cell surface markers (CD11b and CD14) confirmed that the inhibition of proliferation is associated with differentiation especially toward macrophage-like morphology. Interestingly, 3-HK at 5 and 10 nM enhanced the effects of all-trans retinoic acid (ATRA) in NB4 cells. Based on these results, 3-HK might become an ideal candidate for treatment of APL patients pending full exploration of its biological functions.

• Journal of Fashion Business
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• v.20 no.2
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• pp.165-180
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• 2016

Capstone design, is a heartfelt cooperation curriculum because the ultimate goal is to train people who already have the ability to complete the tasks of the job without retraining them in the field immediately after being hired. However, there is a need for the design study in the fashion industry where a variety of operating models could be tried; more specifically case studies than engineering. This study was designed to apply to the types of voluntary projects and industrial challenges linked to the different types of virtuous circle window systems over twice in two years. Result capitalization applied to different types of derived forms associated with start-up technology transfer form. In addition, start-up will be done in conjunction with student-centered forms of the participation of Cooperation Coordinator. This was weak in the form of technology transfer interventions which were made as a result of the overall involvement of the industry. In order to elicit the active participation of the industry it is expected that this system will have an ideal company to reflux. Therefore, reflux that created assets to the students, and the reflux of product design created by students in companies professor final a virtuous cycle system operating models that can derive enhancements accept feedback to both students and companies redefining the performing models It presented. This operating model is considered to be able to provide you with a sense of accomplishment and high experiential value to both students and professors, and the industry. In this study, experiments in environmental A Study, silseupbi no support will be given to alternatives to solve them.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1996.04a
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• pp.80-104
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• 1996

The development of routine techniques for the isolation and in vitro maintenance of conducting airway epithelial cells in a differentiated state provides an ideal model to study the factors involved in the regulation of the expression of mucocilicary differentiation. Several key factors and conditions have been identified. These factors and conditions include the use of biphasic culture technique to achieve mucociliary differentiation and the use of such stimulators, the thickness of collagen gel substratum, the calcium level, and vitamin A, and such inhibitors, the growth factors EGF and insulin, and steroid hormones, for mucous cell differentiation. Using the defined culture medium, the life cycle of the mucous cell population in vitro was investigated. It was demonstrated that the majority of the mucous cell population in primary cultures is not involved in DNA replication. However, the mucous cell type is capable of self-renewal in culture and this reproduction is vitamin A dependent. furthermore, differentiation from non-mucous cell type to mucous cell type can be demonstrated by adding back a positive regulator such as vitamin A to the “starved” culture. Cell kinetics data suggest that vitamin A-dependent mucous cell differentiation in culture is a DNA replication-independent process and the process is inhibited by TGF-${\beta}$1.

• Proceedings of the Korean Society of Crop Science Conference
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• 2001.09a
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• pp.72-90
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• 2001

Environment agriculture carried out from 1999 in Daeho reclaimed saline area, located in central east cost of Choongnam Korea, resulted in dramatic reduction of amount of nitrogen fertilizer and application times and amount of pesticides. The ecological status of Daeho reclaimed saline area was considered to still very sound from the results of ecological survey on flora and fauna. However, it was desirable to adapt precision agriculture for production of high eating quality of rice and preservation of Daeho ecosystem. Especially, precise application of nitrogen and phosphorus fertilizer was recommendable for prevention of water pollution in environment rice cultivation by duck or mud snail or crab. The bioefficacy of Scirpus maritimus and Echinochloa crus-galli in paddy field of environment rice cultivation by duck or mud snail or crab in Daeho reclaimed saline area was revealed very low. Therefor, it was concluded that the pre-measures of reduction of natural weed population were necessary for successful environment agriculture. The most desirable and ideal environmentally sound agriculture in Daeho reclaimed saline area was performance of crop rotation, introduction of legume crops and green manure crops, and also, simultaneous management of crop production and animal husbandry for smooth flow of energy cycle within the closed Daeho ecosystem.

• Journal of the Korean Society of Clothing and Textiles
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• v.42 no.4
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• pp.571-583
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• 2018

'Dress of the Year' by the UK Fashion Museum in Bath suggested an ideal role for a fashion museum and created fashion history along with the development of fashion journalism. A case study and literature research identified the characteristics of this scheme in terms of roles and functions for a fashion museum and defined them as: suggestion of collection cases, data construction for fashion research, and contribution to fashion critique. First, it suggested a good case of collection process. The 'Dress of the Year' creates a museum identity with a collection selected by designated journalist reviewer every year in order to maintain and strengthen a virtuous cycle. Second, it contributed to the accumulation of data for fashion research. The vast amount of data accumulated for more than 50 years became a fashion history that shows the change of fashion trends with a value of public confidence. It presented the possibilities of fashion research in various perspectives. Third, it contributed to the development of fashion criticism. The development of fashion journalism was conducted on the initiative of 'Dress of the Year' as well as contributed to the birth and growth of fashion journalists.

• International Journal of Highway Engineering
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• v.19 no.5
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• pp.1-11
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• 2017

PURPOSES : This study is aimed at development of a stochastic pavement deterioration forecasting model using National Highway Pavement Condition Index (NHPCI) to support infrastructure asset management. Using this model, the deterioration process regarding life expectancy, deterioration speed change, and reliability were estimated. METHODS : Eight years of Long-Term Pavement Performance (LTPP) data fused with traffic loads (Equivalent Single Axle Loads; ESAL) and structural capacity (Structural Number of Pavement; SNP) were used for the deterioration modeling. As an ideal stochastic model for asset management, Bayesian Markov multi-state exponential hazard model was introduced. RESULTS:The interval of NHPCI was empirically distributed from 8 to 2, and the estimation functions of individual condition indices (crack, rutting, and IRI) in conjunction with the NHPCI index were suggested. The derived deterioration curve shows that life expectancies for the preventive maintenance level was 8.34 years. The general life expectancy was 12.77 years and located in the statistical interval of 11.10-15.58 years at a 95.5% reliability level. CONCLUSIONS : This study originates and contributes to suggesting a simple way to develop a pavement deterioration model using the total condition index that considers road user satisfaction. A definition for level of service system and the corresponding life expectancies are useful for building long-term maintenance plan, especially in Life Cycle Cost Analysis (LCCA) work.

• The Bulletin of The Korean Astronomical Society
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• v.42 no.2
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• pp.75.1-75.1
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• 2017

Ram pressure due to the intracluster medium (ICM) is known to play a crucial role in removing the cool gas content of a galaxy on a short timescale, potentially driving a star forming galaxy to evolve into a red passive population. Although many HI imaging studies find clear evidence of diffuse atomic gas stripping from cluster galaxies, it is still debatable whether the ram pressure can also strip dense molecular gas. NGC 4522, a Virgo spiral, undergoing strong ram pressure stripping, is one of the few cases where extraplanar CO emission together with stripped HI gas and $H{\alpha}$ knots has been identified, providing an ideal laboratory to study the molecular gas stripping event and the extraplanar star formation activity. The aim of this work is to investigate the origin of extraplanar molecular clouds near NGC 4522 (e.g. stripped or forming in situ), and to probe a relation between the molecular gas surface density and the star formation rate (i.e. the Kennicutt-Schmidt law) at sub-kpc scale, especially in the extraplanar space, using ALMA Cycle 3 CO data and $H{\alpha}$ data of NGC 4522. We present the results from our ALMA observations, and discuss possible scenarios for the origin of extraplanar molecular clouds and to characterize the star formation activity associated with stripped gas outside the galactic disk.