• Molecular & Cellular Toxicology
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• v.1 no.1
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• pp.62-71
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• 2005

For toxicity model in the kidney, renal cell carcinoma (RCC) is one of the most important model to assess the structural and functional alterations. Most RCCs are sporadic, and environmental agents are suspected to play a role in the etiology of the disease. In this study, we discovered novel evidence for previously unknown gene expression patterns related to progression according to cancer stage in RCC. Four clear cell RCC tissue samples along with five corresponding patient-matched normal kidney tissue samples were obtained from patients undergoing partial or radical nephrectomy. To examine the difference of gene expression profile in clear cell RCC, radioactive cDNA microarrays were used to evaluate changes in the expression of 1,152 genes in a total. Using $^{33}P-labeled$ probes, this method provided highly sensitive gene expression profiles including drug metabolism, and cellular signaling. 29 genes were identified with expression levels that differed by more than 2.0 value of z-ratio, compared with that in control. Whereas expression of 38 genes were decreased by less than-2.0 value of z-ratio. In conclusion, this study has identified 67 gene expression alterations in clear-cell type of RCC. Most notably, genes involved in cell growth were up-regulated in stage I more than stage III whereas genes involved in signal transduction were down-regulated in which both stage I and stage III. The identified alteraions of gene expression will likely give in sight in to clear cell RCC and tumor progression.

• Journal of Oriental Neuropsychiatry
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• v.23 no.4
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• pp.11-36
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• 2012

Objectives : Sleep Disorders are very common in clinical stages and there are many reports and papers regarding this subject. I try to understand the present state of sleep research in JON (The Journal of Oriental Neuropsychiatry) for the benefits of clinical practice. Methods : We searched and read every article on JON from 1990 to 2012 and selected ones that are related to Sleep Disorder; then analyzed the data to 5 categories, like literature study, case study, Clinical Data-Analysis study, experimental study, and clinical trial. Results : 1. We Found 41 articles relating to sleep disorder in JON form 1999 to 2012, and there were 9 literature studies, 13 case studies, 13 Clinical Data-Analysis studies, 4 experimental studies, and 2 clinical trials. 2. There were Sa-Am Acupuncture Method, Pharmacopuncture, electroacupuncture, and Auricular acupuncture to treat Sleep Disorder. 3. There were many additional treatments like Purgative Therapy, etc. 4. They reported the ordinary sleep pattern of Soeumin and Soyangin, too. 5. In the experimental study, they reported several herbs, herbal prescription on the expression of melatonin receptors, and Punsimgeimgamibang on insomnia, anxiety, emotionality in rats. 6. There were 2 clinical trials, one for Hwabyung-patient with insomnia by acupuncture treatment and another for insomnia in the elderly by ETF-I program. 7. There were 2 case of other sleep disorder (enuresis, sleepwalking) and 2 literature study of dream. Conclusions : In JON regarding sleep disorder, the majority was due to insomnia. Therefore, we also have to expand our sight into other sleep diseases. We need more clinical trials and experimental researches for the construction of EBM Sleep Disorder in Oriental Neuropsychiatry.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2006.05a
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• pp.361-362
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• 2006

This paper presents the robust design of gripper part for a high-speed LCD (Liquid Crystal Display) transfer system. In this paper, the 1st DOE (Design of Experiment) is conducted to find out main-effect factors fur the design of gripper part. Thirty-six experiments are performed using $ANSYS^{(R)}$ and their results are statistically analyzed using $MINITAB^{(R)}$, which shows that the factors, i.e., First-width, Second-width, Rec-width, and thickness of gripper part, are more important than other factors. The main effect plots shows that the maximum deflection and mass of gripper part are minimized by increasing First-width, Second-width, Rec-width and thickness. The 2nd DOE is conducted to obtain RSM (Response Surface Method) equation. The CCD (Central Composite Design) technique with four factors is used. Optimum design is conducted using the RSM equation. Genetic algorithm is used for optimal design. Six sigma robust design is conducted to find out a guideline for control range of design parameter. To obtain six sigma level reliability, the standard deviations of design parameters are shown to be controlled within 5% of average design value.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.7 no.8
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• pp.1933-1954
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• 2013

Multiple wireless devices are being widely deployed in Intelligent Transportation System (ITS) services on the road to establish end-to-end connection between vehicle-to-vehicle (V2V) and vehicle-to-infrastructure (V2I) networks. Vehicular ad hoc networks (VANETs) play an important role in supporting V2V and V2I communications (also called V2X communications) in a variety of urban environments with distinct topological characteristics. In fact, obstacles such as big buildings, moving vehicles, trees, advertisement boards, traffic lights, etc. may block the radio signals in V2X communications. Their impact has been neglected in VANET research. In this paper, we present a realistic and efficient radio propagation model to handle different sizes of static and moving obstacles for V2X communications. In the proposed model, buildings and large moving vehicles are modeled as static and moving obstacles, and taken into account their impact on the packet reception rate, Line-of-sight (LOS) obstruction, and received signal power. We use unsymmetrical city map which has many dead-end roads and open faces. Each dead-end road and open faces are joined to the nearest edge making a polygon to model realistic obstacles. The simulation results of proposed model demonstrates better performance compared to some existing models, that shows proposed model can reflect more realistic simulation environments.

• The Journal of the Korea Contents Association
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• v.12 no.7
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• pp.40-53
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• 2012

In the past, the elements that determine the movie performance were directors, movie stars, the number of opening screens, on-line ratings or distributing agencies. However, the word-of-mouth effect has changed this trends. So the influence of word of mouth grows more and more strong at this stage of the Internet and smart phones being widely prevalent. I fix my sight upon SNS which is one of the medium of arousing the word-of-mouth effect, and I have a purpose to cast light upon a real example of the influence of SNS on the movie performance. The way is to analyze SNS activities that accompany the process of production and showing of , which is said to have had an beneficial effect of SNS among the enormously successful movies last year. It is relevant to provide a new milestone regarding the movie performance through the successful case of SNS activities by examining the word-of-mouth activities through SNS in the manner of the period division of the pre-release, the early stage of release and the maturity.

• Korean Journal of Agricultural Science
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• v.2 no.1
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• pp.265-279
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• 1975

This study was conducted to investigate the development of Gab river-basin which was a part of the farm land enlargement to contribute to the increased production of food. The results were as follows; 1. Gab river has the upper stream which occupy 50 percent in moumtains and the mid-stream in the Daejeon city area, and the downstream in a field which is about 22.9 percent in which farming area per household is 0.82 ha., agricultural population is 76 percent except of Daejeon city. Also, urban enlargement of mid-stream basin and development of industrial area in the lower stream diminish farm land. Consequently, this area should be developed to farm land to increase farming size. 2. There is no possibility to develop farm land in mountains of which (64.9 percent) is forests and in midstream which was constructed river-improvement. But Weonjeong area and Yongcheon area will be effective area. 3. If river banks of Weonjeong area will make straight with cost of construction 195,000,000 won, bank length 6 km will be useless, water will flow smoothly, flood will be prevented, farm land will develop 21.66 ha in which rice will produce annually 81.698 M/T which is about 10,860,000 won. 4. This area has good conditions of development. that is, investment efficiency (B/C) is 1.47 more than 1.00. 5. This area is a multiple purpose development district. The reasons are that there are beautiful mountains and a reservoir to be expected to construct, so it will be a sight seeing district in the vicinity of Daejeon city. 6. If Honam railway double line and river straight construction had executed simultaneously, cost of construction 50,000,000 won would have saved.

• Journal of Sasang Constitutional Medicine
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• v.14 no.2
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• pp.1-9
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• 2002

I think that the study on the ${\ulcorner}$DongMuSunSaSaSangYakSungSangHumGoGa${\lrcorner}$ of ${\ulcorner}$DongMuYooGo${\lrcorner}$ is basic material explaining the character of sasang-herb and prescription. Through the study on the ${\ulcorner}$DongMuSunSaSaSangYakSungSangHumGoGa${\lrcorner}$'s origin and meaning, I can take the result as follows. The first, that is composed of total 237 herbs of 90 spleen-herb (Soeumin-herb), 61 kidney-herb (Soyangin-herb), 67 lung-herb (Taeeumin-herb) and 19 liver-herb (Taeyangin-herb). The second, the origin of that is ${\ulcorner}$JeJungSinPyun${\lrcorner}$, ${\ulcorner}$BangYakHapPyun${\lrcorner}$ and ${\ulcorner}$EuiHakIpMum${\lrcorner}$. And DongMu classified traditional YakSungGa as spleen-herb, kidney-herb, lung-herb and liver-herb which is suitable to Sasangin, not created that. So we can know that the first understanding for DongMu' s herb is focused on the traditional YakSungGa. The third, DongMu's unique terminology of spleen-herb, kidney-herb, lung-herb and liver herb show his sight of symptom, disease and pharmacology, that is focused on small JangBu. The forth, through herb-nature gathered from traditional YakSungGa, that purposed to classfying each constitutional herb. So we can know his idea that the choice of herb is not in general efficacy but in personal constitution. As mentioned abovet, that can refer to an herbal argument of DongMu and ${\ulcorner}$DongMuYooGoYakSungGa${\lrcorner}$ that make known to be common can refer to an prescriptional argument of DongMu.

• Journal of Dental Anesthesia and Pain Medicine
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• v.19 no.1
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• pp.29-36
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• 2019

Background: An inability to cope with threatening dental stimuli, i.e., sight, sound, and sensation of airotor, manifests as anxiety and behavioral management problems. Behavior modification techniques involving pre-exposure to dental equipment will give children a first-hand experience of their use, sounds, and clinical effects. The aim of this study was to compare the techniques of Tell-Show-Play-doh, a smartphone dentist game, and a conventional Tell-Show-Do method in the behavior modification of anxious children in the dental operatory. Methods: Sixty children in the age group of 4-8 years, with Frankl's behavior rating score of 2 or 3, requiring Class I and II cavity restorations were divided into three groups. The groups were Group 1: Tell-Show-Play-doh; Group 2: smartphone dentist game; and Group 3: Tell-Show-Do technique and each group comprised of 20 children. Pulse rate, Facial Image Scale (FIS), Frankl's behavior rating scale, and FLACC (Face, Leg, Activity, Cry, Consolability) behavior scales were used to quantify anxious behavior. Operator compliance was recorded through a validated questionnaire. Results: The results showed lower mean pulse rates, lower FIS and FLACC scores, higher percentage of children with Frankl's behavior rating score of 4, and better operator compliance in both the Tell-Show-Play-doh and smartphone dentist game groups than in the conventional Tell-Show-Do group. Conclusion: The Tell-Show-Play-doh and smartphone dentist game techniques are effective tools to reduce dental anxiety in pediatric patients.

• The Bulletin of The Korean Astronomical Society
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• v.43 no.2
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• pp.46.1-46.1
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• 2018

The Fast Imaging Solar Spectrograph (FISS) on the Goode Solar Telescope (GST) at Big Bear Solar Observatory is the imaging Echelle spectrograph developed by the Solar Astronomy Group of Seoul National University and the Solar and Space Weather Group of Korea Astronomy and Space Science Institute. The instrument takes spectral data from a region on the Sun in two spectral bands simultaneously. The imaging is done by the organization of intensity data obtained from the fast raster scan of the slit over the field of view. Since the scan repeats many times, the whole set of data can be used to construct the movies of monochromatic intensity at arbitrary wavelengths within the spectral bands, and those of line-of-sight velocity inferred from different spectral lines. So far there are two standard observing configurations: one recording the $H{\alpha}$ line and the Ca II 8542 line simultaneously, and the other recording the Na I D2 line and Fe I 5435 line simultaneously. We have developed the procedures to produce the standard data for each observing configuration. The procedures include the spatial alignment, the correction of spectral shift of instrumental origin, and the lambdameter measurement of the line wavelength. The standard data include the movie of continuum intensity, the movies of intensity and velocity inferred from a chromospheric spectral line, the movies of intensity and velocity inferred from a photospheric line. The processed standard data will be freely available online (fiss.snu.ac.kr) to be used for research and public outreach. Moreover, the IDL procedures will be provided on request as well so that each researcher can adapt the programs for their own research.

• Journal of The Korean Association For Science Education
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• v.27 no.5
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• pp.456-464
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• 2007

The aims of this research are to analyze the representations and conceptual sequence of eye vision in Korean science textbooks and to suggest a contents construct about eye vision where the conceptual sequence is considered. Research method was literature review, and the literatures that were used for analysis were the 7th Korean science curriculum which was revised in 1997, and the science and physics textbooks developed based on the 7th Korean science curriculum. The research results are as follows: 1) Although the science curriculum seems to have no problem on sequence in the eye vision concepts, the science and physics textbooks based on the curriculum reveal problems on the sequence in the eye vision concepts; 2) Some Korean science textbooks explain retinal image formation according to the Alhazen's idea, except in inverse image; 3) Some Korean science textbooks explain about the reasons of near- and far-sightedness without consistency between the textbooks for 7th and 8th grade students; 4) A few Korean science textbooks give an inappropriate explanation about the principle of eye sight correction by eye glasses; 5) According to the analysis result, the concepts related to eye vision should be presented in the order of explanation about light refraction phenomena, image formation process by convex lens, structure of human eye and retinal image formation process, correction of eye sight using lens.