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Second look arthroscopic findings after microfracture surgery in osteoarthritic knee (퇴행성 슬관절염에서 미세천공술 후 이차 관절경 소견)

  • Bae, Dae Kyung;Kim, Jin Moon;Lee, Jeong Heui;Park, Yong Koo
    • Journal of the Korean Arthroscopy Society
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    • v.3 no.2
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    • pp.85-90
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    • 1999
  • Purpose : The purpose of this study is to evaluate the clinical and histological results of the osteoarthritic patients who had second look arthroscopy after microfracture surgery. Materials and Methods : From Oct. 1997 to Dec. 1998, 46 patients, 48 knees were treated by microfracture technique. In the 22 patients, 24 knees, 'second-look' arthroscopies and biopsies were performed at 6 months following microfracture. Three patients were men and 19 patients were women. Average age of the patients were 58 years (range, 40-75 years). The average follow up period was 12 months(7-20 months). We analysed clinical results according to the nine-point scale. Also we observed type II collagen formation with immunohistochemical staining. Results : Clinical results were excellent in 83% and good in 17%. Among the 24 knees, more than 80% areas of chondral defect were covered with regenerated cartilage in 21 knees. Histologically, the regenerated tissue appears to be a hybrid of hyaline cartilage and fibrocartilage. Regenerated cartilage contains variable amount of type II collagen with immunohistochemical staining. Conclusion : Most of the patients had significant improvement clinically. 'Second-look' showed that the chondral defect areas were covered with newly grown grayish white tissue. Microfracture in the full thickness chondral defect provides and enriched environment for cartilaginous tissue regeneration.

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Clinical and Histopathological Study in Repaired Cartilage after Microfracture Surgery in Degenerative Arthritis of the Knee (퇴행성 슬관절염에서 미세 천공술후 재생된 연골의 임상 및 병리조직학적 연구)

  • Bae, Dae-Kyung;Yoon, Kyoung-Ho;So, Jae-Keun
    • Journal of Korean Orthopaedic Sports Medicine
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    • v.4 no.1
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    • pp.18-28
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    • 2005
  • Purpose: The purpose of this study is to evaluate the clinical, radiological and histopathological results after microfracture surgery for degenerative arthritis of the knee. Materials and Methods: From Oct. 1997 to Dec. 1998, 48 knees in 46 patients were treated by microfracture technique. Their mean age at the time of operation was 56 years(range, 40-75 years) and mean period of follow-up study was one year(range, 7-20 months). For 24 knees in 22 patients, 'second-look' arthroscopies and biopsies were performed at 6 months following microfracture. At the last follow up clinical results were evaluated with Baumgaertner's scale. The specimens of 24 cases were stained with H-E, Safranin-O, and Masson's trichrome. Eighteen of 24 cases were stained immunohistochemically and the Western blotting test was performed on 12 cases for type II collagen. We analyzed the relationship of the Western blotting for type II collagen with clinical score, preoperative varus deformity, joint space widening in radiological result, extent of repaired articular cartilage in '2nd-look' arthroscopic findings, patient's age and weight. Results: Clinical results were excellent in 90% and good in 10%. Among the 24 knees, more than 80% of areas of chondral defect were covered with regenerated cartilage in 21 knees Histologically, the repaired tissue appears to be a hybrid of hyaline cartilage and fibrocartilage. Repaired cartilage contains variable amounts of type II collagen with immunohistochemical staining. The results of the Western blotting test were similar. The amounts of type II collagen formation had positive correlation with the extent of repaired cartilage and preoperative varus deformity. Conclusion: 'Second-look' showed that the chondral defect areas were covered with newly grown grayish white tissue. Articular cartilage repair was confirmed with histological and immunohisto-chemical study qualitatively, and the amount of type II collagen was calculated with the Western blotting test quantitatively. The exact nature and fate of repaired cartilagenous tissues need further long term follow-up study. The results of this study provide the rationale to select osteoarthritic patients indicated for microfracture surgery.

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A Collaborative Filtering System Combined with Users' Review Mining : Application to the Recommendation of Smartphone Apps (사용자 리뷰 마이닝을 결합한 협업 필터링 시스템: 스마트폰 앱 추천에의 응용)

  • Jeon, ByeoungKug;Ahn, Hyunchul
    • Journal of Intelligence and Information Systems
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    • v.21 no.2
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    • pp.1-18
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    • 2015
  • Collaborative filtering(CF) algorithm has been popularly used for recommender systems in both academic and practical applications. A general CF system compares users based on how similar they are, and creates recommendation results with the items favored by other people with similar tastes. Thus, it is very important for CF to measure the similarities between users because the recommendation quality depends on it. In most cases, users' explicit numeric ratings of items(i.e. quantitative information) have only been used to calculate the similarities between users in CF. However, several studies indicated that qualitative information such as user's reviews on the items may contribute to measure these similarities more accurately. Considering that a lot of people are likely to share their honest opinion on the items they purchased recently due to the advent of the Web 2.0, user's reviews can be regarded as the informative source for identifying user's preference with accuracy. Under this background, this study proposes a new hybrid recommender system that combines with users' review mining. Our proposed system is based on conventional memory-based CF, but it is designed to use both user's numeric ratings and his/her text reviews on the items when calculating similarities between users. In specific, our system creates not only user-item rating matrix, but also user-item review term matrix. Then, it calculates rating similarity and review similarity from each matrix, and calculates the final user-to-user similarity based on these two similarities(i.e. rating and review similarities). As the methods for calculating review similarity between users, we proposed two alternatives - one is to use the frequency of the commonly used terms, and the other one is to use the sum of the importance weights of the commonly used terms in users' review. In the case of the importance weights of terms, we proposed the use of average TF-IDF(Term Frequency - Inverse Document Frequency) weights. To validate the applicability of the proposed system, we applied it to the implementation of a recommender system for smartphone applications (hereafter, app). At present, over a million apps are offered in each app stores operated by Google and Apple. Due to this information overload, users have difficulty in selecting proper apps that they really want. Furthermore, app store operators like Google and Apple have cumulated huge amount of users' reviews on apps until now. Thus, we chose smartphone app stores as the application domain of our system. In order to collect the experimental data set, we built and operated a Web-based data collection system for about two weeks. As a result, we could obtain 1,246 valid responses(ratings and reviews) from 78 users. The experimental system was implemented using Microsoft Visual Basic for Applications(VBA) and SAS Text Miner. And, to avoid distortion due to human intervention, we did not adopt any refining works by human during the user's review mining process. To examine the effectiveness of the proposed system, we compared its performance to the performance of conventional CF system. The performances of recommender systems were evaluated by using average MAE(mean absolute error). The experimental results showed that our proposed system(MAE = 0.7867 ~ 0.7881) slightly outperformed a conventional CF system(MAE = 0.7939). Also, they showed that the calculation of review similarity between users based on the TF-IDF weights(MAE = 0.7867) leaded to better recommendation accuracy than the calculation based on the frequency of the commonly used terms in reviews(MAE = 0.7881). The results from paired samples t-test presented that our proposed system with review similarity calculation using the frequency of the commonly used terms outperformed conventional CF system with 10% statistical significance level. Our study sheds a light on the application of users' review information for facilitating electronic commerce by recommending proper items to users.

Optimization of Support Vector Machines for Financial Forecasting (재무예측을 위한 Support Vector Machine의 최적화)

  • Kim, Kyoung-Jae;Ahn, Hyun-Chul
    • Journal of Intelligence and Information Systems
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    • v.17 no.4
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    • pp.241-254
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    • 2011
  • Financial time-series forecasting is one of the most important issues because it is essential for the risk management of financial institutions. Therefore, researchers have tried to forecast financial time-series using various data mining techniques such as regression, artificial neural networks, decision trees, k-nearest neighbor etc. Recently, support vector machines (SVMs) are popularly applied to this research area because they have advantages that they don't require huge training data and have low possibility of overfitting. However, a user must determine several design factors by heuristics in order to use SVM. For example, the selection of appropriate kernel function and its parameters and proper feature subset selection are major design factors of SVM. Other than these factors, the proper selection of instance subset may also improve the forecasting performance of SVM by eliminating irrelevant and distorting training instances. Nonetheless, there have been few studies that have applied instance selection to SVM, especially in the domain of stock market prediction. Instance selection tries to choose proper instance subsets from original training data. It may be considered as a method of knowledge refinement and it maintains the instance-base. This study proposes the novel instance selection algorithm for SVMs. The proposed technique in this study uses genetic algorithm (GA) to optimize instance selection process with parameter optimization simultaneously. We call the model as ISVM (SVM with Instance selection) in this study. Experiments on stock market data are implemented using ISVM. In this study, the GA searches for optimal or near-optimal values of kernel parameters and relevant instances for SVMs. This study needs two sets of parameters in chromosomes in GA setting : The codes for kernel parameters and for instance selection. For the controlling parameters of the GA search, the population size is set at 50 organisms and the value of the crossover rate is set at 0.7 while the mutation rate is 0.1. As the stopping condition, 50 generations are permitted. The application data used in this study consists of technical indicators and the direction of change in the daily Korea stock price index (KOSPI). The total number of samples is 2218 trading days. We separate the whole data into three subsets as training, test, hold-out data set. The number of data in each subset is 1056, 581, 581 respectively. This study compares ISVM to several comparative models including logistic regression (logit), backpropagation neural networks (ANN), nearest neighbor (1-NN), conventional SVM (SVM) and SVM with the optimized parameters (PSVM). In especial, PSVM uses optimized kernel parameters by the genetic algorithm. The experimental results show that ISVM outperforms 1-NN by 15.32%, ANN by 6.89%, Logit and SVM by 5.34%, and PSVM by 4.82% for the holdout data. For ISVM, only 556 data from 1056 original training data are used to produce the result. In addition, the two-sample test for proportions is used to examine whether ISVM significantly outperforms other comparative models. The results indicate that ISVM outperforms ANN and 1-NN at the 1% statistical significance level. In addition, ISVM performs better than Logit, SVM and PSVM at the 5% statistical significance level.

Recent Progress in Air-Conditioning and Refrigeration Research : A Review of Papers Published in the Korean Journal of Air-Conditioning and Refrigeration Engineering in 2010 (설비공학 분야의 최근 연구 동향 : 2010년 학회지 논문에 대한 종합적 고찰)

  • Han, Hwa-Taik;Lee, Dae-Young;Kim, Seo-Young;Choi, Jong-Min;Kim, Su-Min;Kwon, Young-Chul;Baik, Yong-Kyu
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.23 no.6
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    • pp.449-469
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    • 2011
  • This article reviews the papers published in the Korean Journal of Air-Conditioning and Refrigerating Engineering during 2010. It is intended to understand the status of current research in the areas of heating, cooling, ventilation, sanitation, and indoor environments of buildings and plant facilities. Conclusions are as follows. (1) Research trends of thermal and fluid engineering have been surveyed as groups of general thermal and fluid flow, fluid machinery, and new and renewable energy. Various topics were presented in the field of general thermal and fluid flow. Research issues mainly focused on the thermal reliability of axial fan and compressor in the field of fluid machinery. Studies on the design of ground source heat pump systems and solar chemical reactors were executed in the field of new and renewable energy. (2) Research works on heat transfer area have been reviewed in the categories of heat transfer characteristics and industrial heat exchangers. Researches on heat transfer characteristics included heat transfer in thermoelectric cooling/power generation systems, combined heat and power systems, carbon nano fluid with PVP, channel filled with metal foam and smoke ventilation in a rescue station of a railroad tunnel. Also the studies on flow boiling of R123/oil mixture in a plain tube bundle and R410A charge amount in an air cooled mini-channel condenser were reported. In the area of industrial heat exchangers, researches on plate heat exchanger, shell and tube heat exchanger, enthalpy exchanger, micro channel PCHE were performed. (2) Research works on heat transfer area have been reviewed in the categories of heat transfer characteristics and industrial heat exchangers. Researches on heat transfer characteristics included heat transfer in thermoelectric cooling/power generation systems, combined heat and power systems, carbon nano fluid with PVP, channel filled with metal foam and smoke ventilation in a rescue station of a railroad tunnel. Also the studies on flow boiling of R123/oil mixture in a plain tube bundle and R410A charge amount in an air cooled mini-channel condenser were reported. In the area of industrial heat exchangers, researches on plate heat exchanger, shell and tube heat exchanger, enthalpy exchanger, micro channel PCHE were performed. (3) Refrigeration systems with alternative refrigerants such as hydrocarbons, mixed refrigerants, and CO2 were studied. Performance improvement of refrigeration systems are tried applying various ideas of refrigerant subcooling, dual evaporator with hot gas bypass control and feedforward control. The hybrid solar systems combining the solar collection devices with absorption chillers or compression heat pumps are simulated and studied experimentally as well to improve the understanding and the feasibility for actual applications. (4) Research trend in the field of mechanical building facilities has been found to be mainly focused on field applications rather than performance improvements. Various studies on heating and cooling systems, HVAC facilities, indoor air environments and energy resources were carried to improve the maintenance and management of building service equipments. In the field of heating and cooling systems, papers on a transformer cooling system, a combined heat and power, a slab thermal storage and a heat pump were reported. In the field of HVAC facilities, papers on a cooling load, an ondol and a drying were presented. Also, studies on HVAC systems using unutilized indoor air environments and energy resources such as air curtains, bioviolence, cleanrooms, ventilation, district heating, landfill gas were studied. (5) In the field of architectural environment and energy, studies of various purposes were conducted such as indoor environment, building energy, renewable energy and green building. In particular, renewable energy and building energy-related researches have mainly been studied reflecting the global interest. In addition, many researches which related the domestic green building certification of school building were performed to improve the indoor environment of school.

Studios on Silkworm Selection by Use of Anesthetic(2) (The Effect for next Generation through Anesthesia) (마취제처리에 의한 잠아선발 연구 (2) (마취잠의 차대에 미치는 영향))

  • Choe, Byong-Hee;Lee, Sang-Poong
    • Journal of Sericultural and Entomological Science
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    • v.15 no.2
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    • pp.15-20
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    • 1973
  • This will be second publication regard with silkworm selection using anesthetic followed by previous report. This treatise investigated for nacorsis recovery concerned with silkworm health through more directions than the previous paper. After the author has found a possibility of silkworm seperation through nacorsis recovery, he has recommended to use Balance Health (BH) value system to evaluate or identify silkworm health and to produce better homogeneous silkworm eggs. Also, the author has continued the observation for the next generation how once nacortized parents affect to their family. The obtained results are summarized as followings. 1. Basic investigation a) Hybrid silkworm variety recovers from nacorsis earlyer than pure line because it is stronger. b) Strong pure line variety recovers from nacorsis earlyer than weak one because it is stronger. c) Male worm recovers from nacorsis earlyer than female worm because it is stronger. 2. Establishment of Balance Health(BH) value system. In order to identify each seperated group by nacorsis and their family, the following Balance Health (BH) value indicating system was established.(Table Omitted) 3. In order to select better silkworm during breeding service, the BH value indicating system is strongly recommended. That is, in case BH value is smaller than four, it would be strong group or in case BH value is larger than four, it would be weak group. 4. Once nacortized parents do not harm any nature for next generation regardless P$_1$ or F$_1$ production. 5. The seperation through nacorsis may delay retrograde phenomenon some years than other case, so, this system should be used for pure line production every year. 6. It is recommended to nacortize silkworm for five minutes on breeding purpose, but two and half minutes on pure lines reproduction at fifth instar. 7. This report has been discussed in relation to practical industry promotion aspects, but there are many subjects to be solved from academical aspect in future

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Investigation of Vascular Plants in the Eco-Arboretum Site, Mt. Gumwon (금원산 생태수목원 조성 부지의 관속식물상 연구)

  • Oh, Hyun-Kyung;Shin, Hyun-Tak;Beon, Mu-Sup
    • Korean Journal of Plant Resources
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    • v.21 no.2
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    • pp.117-127
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    • 2008
  • The vascular plants in the Eco-Arboretum site, Mt. Gumwon appeared to be 369 taxa; 84 families, 217 genera, 319 species, 43 varieties and 7 forms. Based on the list of the rare plants, 2 taxa existed in the studied areas; Abies koreana (Preservation priority order; No. 73), Paeonia obovata (No. 97) and based on the list of Korean endemic plants, 12 families, 14 genera, 11 species, 3 varieties, 1 hybrid, 15 taxa existed; Cephalotaxus koreana, Abies koreana (Planted species), Carex okamotoi, Salix hallaisanensis, Salix purpurea var. japonica, Clematis trichotoma, Thalictrum actaefolium, Lespedeza ${\times}$ tomentella, Vicia nipponica, Stewartia koreana, Hypericum attenuatum var. confertissimum, Paulownia coreana (Planted species), Weigela subsessilis, Aster koraiensis (Planted species). Specific plant species by floral region were total 38 taxa; Paeonia obovata in class V , 13 taxa (Lilium leichtlinii var. tigrinum, Betula costata, Betula davurica, Ulmus davidiana, Spiraea frutschiana, Prunus maackii, Syringa reticulata var. mandshurica, Cynanchum inamoenum, Lonicera subhispida, Cacalia firma, etc.) in class III , 5 taxa (Heloniopsis orientalis, Chrysosplenium pilosum, Acer triflorm, Viola tokubuchiana var. takedana, Teucrium veronicoides, etc.) in Class II . 19 taxa (Dryopteris erythrosora, Arisaema ringens, Veratrum versicolor, Polygonatum inflatum, Salix glandulosa, Betula schmidtii, Alnus hirsuta, Quercus variabilis, Aconitum japuense, Dicentra spectabilis, Chrysosplenium flagelliferum, Impatiens noli-tangere, Ilex macropoda, Tilia amurensis, Fraxinus mandshurica, Trigonotis icumae, etc.)in class I . The naturalized plants in this site were 5 families, 13 genera, 15 taxa (Rumex acetocella, Rumex obtusifolius, Trifolium repens, Oenothera odorata, Erigeron annuus, Erigeron philadelphicus, Bidens frondosa, Taraxacum officinale, etc.) and naturalization rate was 4.1% of all 369 taxa vascular plants.

Effects of anatase-rutile phase transition and grain growth with WO3 on thermal stability for TiO2 SCR catalyst (WO3 첨가에 의한 TiO2계 SCR 촉매의 상전이 및 입자성장이 고온안정성에 미치는 영향)

  • Yoon, Sang-Hyeon;Kim, Jang-Hoon;Shin, Byeong-Kil;Park, Sam-Sik;Shin, Dong-Woo;Lee, Hee-Soo
    • Journal of the Korean Crystal Growth and Crystal Technology
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    • v.21 no.4
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    • pp.181-186
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    • 2011
  • Thermal stability of the $TiO_2$ SCR catalyst with W03 loading was investigated in terms of structural and morphological analyses. The $TiO_2$ catalysts with 10 w% $WO_3$ content and without $WO_3$ were prepared. which were heat-treated at $800^{\circ}C$ for 5 h. It was found that the catalytic acidity was decreased by thermal degradation in the $WO_3-TiO_2$ specimen that relatively less than the $TiO_2$ specimen from FT-IR analysis. The phase transition of the $TiO_2$ catalyst from anatase to rutile was increased by heal-treatment, and the percentage of the rutile phase was 28.4 % in the $WO_3-TiO_2$ and 22.9 % in the $TiO_2$. A shell region of $WO_3$ distinguished from a $TiO_2$ particle was also observed in the grain boundary region, and the $WO_3$ led to the suppression of grain growth. It could be confirmed that the suppression of grain growth can contribute to the improvement of catalytic properties for thermal stability more than the increase of anatase-rutile phase transformation which cause the reduction of the catalytic activity in the $TiO_2$ SCR catalyst by the presence of $WO_3$.

The Morphological characteristics of four Korean Abalone species in Nordotis (국내연안에 분포하는 둥근전복속 4종의 형태적 특징 고찰)

  • Won, Seung-Hwan;Kim, Soo-Kang;Kim, Sun-Chan;Yang, Byung-Kyu;Lim, Bong-Soo;Lee, Je-Hee;Lim, Han Kyu;Lee, Jung-Sick;Lee, Jun-Sang
    • The Korean Journal of Malacology
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    • v.30 no.1
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    • pp.87-93
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    • 2014
  • The Morphological characteristics of four species of Korean Abalone species, Nordotis discus hannai, N. discus discus, N. gigantea, N. madaka were compared. then Phenotypic traits were characterized. we collected from coast of samchonpo, sacjon-si, Gyeongsangnam-do and jeju-do of korea 69 individual of Nordotis discus hannai from 2013 December to 2014 January, 180 individual of N. discus, 72 individual of N. gigantea and 54 individual of N. madaka respectively then morphological traits of theses species characteristics were compared. The relationship between Shell length (SL), shell breth (SB), shell height (SH) and total weigh (TW) was expressed by the following equation: SB = 0.6346SL + 3.9082 ($R^2$ = 0.8956), SH = 0.2399SL + 3.2609 ($R^2$ = 0.8024), $TW=0.0009SL^{2.5622}$ ($R^2$ = 0.8088) in the Haliotis discus hannai, SB = 0.7249SL + 1.8035 ($R^2$ = 0.9634), SH = 0.3115SL - 11.223 ($R^2$ = 0.8593), $TW=0.0001SL^{2.9696}$ ($R^2$ = 0.8956) in the H. discus discus, SB = 0.7730SL - 1.1931 ($R^2$ = 0.933), SH = 0.2082SL + 3.2627 ($R^2$ = 0.6927), $TW=0.0002SL^{2.8330}$ ($R^2$ = 0.8431) in the Haliotis gigantea, SB = 0.7513SL - 1.0951 ($R^2$ = 0.913), SH = 0.2618SL - 6.1538 ($R^2$ = 0.6927), $TW=0.0001SL^{2.9614}$ ($R^2$ = 0.9353) in the Haliotis madaka.

Effects of Bisphenol A to interspecific hybrids between marine medaka Oryzias dancena and javanese medaka O. javanicus (바다송사리, Oryzias dancena와 자바송사리, O. javanicus 간 잡종에 대한 비스페놀 A의 효과)

  • Kim, Bong-Seok;Song, Ha-Yeun;Nam, Yoon-Kwon;Kim, Dong-Soo
    • Journal of fish pathology
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    • v.24 no.2
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    • pp.131-139
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    • 2011
  • Bisphenol A (BPA) is mainly used in the production of epoxy resins and polycarbonate plastics, which is a known endocrine disruptor and acutely toxic to aquatic organisms. In this study, estrogenic effect of BPA was investigated on hybrid between Oryzias dancena and O. javanicus (ODJ). ODJ were exposed to BPA of various concentrations (eg. 2.5 mg/L, 5.0 mg/L and 10.0 mg/L) for 56 days. The growth rate, abnormality and the ratio of female and male were observed in test group and control group. As a result, the growth was $14.7{\pm}2.0$ mm in total length (TL) in 2.5 mg/L, $13.7{\pm}2.5$ mm in 5.0 mg/L, $12.8{\pm}2.5$ mm in 10.0 mg/L in test group while it was $18.0{\pm}1.2$ mm in TL in control group which was not treated with bisphenol A. The result showed that the growth decreased as the concentration of BPA increased. The abnormality rate was 13.6% in control group, 65.4% in 2.5 mg/L, 81.3% in 5.0 mg/L and 98.1 % in 10.0 mg/L which showed increase in abnormality as an increase of BPA concentration. As a result of analyzing ratio of sex in the test group and control group, 6.0% was examined to be interspecific in controls, 76.9% in 2.5 mg/L and 100.0% in 5.0 mg/L and 10.0 mg/L. In conclusion, these results suggest that BPA has estrogenic effect on ODJ.