• Title/Summary/Keyword: hybrid method

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Flow Diverter Devices for the Treatment of Unruptured Vertebral Artery Dissecting Aneurysm

  • Kim, Chang Hyeun;Lee, Chi Hyung;Kim, Young Ha;Sung, Soon Ki;Son, Dong Wuk;Lee, Sang Weon;Song, Geun Sung
    • Journal of Korean Neurosurgical Society
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    • v.64 no.6
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    • pp.891-900
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    • 2021
  • Objective : Vertebral artery dissecting aneurysm (VADA) is a very rare subtype of intracranial aneurysms; when ruptured, it is associated with significantly high rates of morbidity and mortality. Despite several discussions and debates, the optimal treatment for VADA has not yet been established. In the last 10 years, flow diverter devices (FDD) have emerged as a challenging and new treatment method, and various clinical and radiological results have been reported about their safety and effectiveness. The aim of our study was to evaluate the clinical and radiological results with the use of FDD in the treatment of unruptured VADA. Methods : We retrospectively evaluated the data of all patients with unruptured VADA treated with FDD between January 2018 and February 2021 at our hybrid operating room. Nine patients with unruptured VADA, deemed hemodynamically unstable, were treated with FDD. Among other parameters, the technical feasibility of the procedure, procedure-related complications, angiographic results, and clinical outcomes were evaluated. Results : Successful FDD deployment was achieved in all cases, and the immediate follow-up angiography showed intra-aneurysmal contrast stasis with parent artery preservation. A temporary episode of facial numbness and palsy was noted in one patient; however, the symptoms had completely disappeared when followed up at the outpatient clinic 2 weeks after the procedure. The 3-6 months follow-up angiography (n=9) demonstrated complete/near-complete obliteration of the aneurysm in seven patients, and partial obliteration and segmental occlusion in one patient each. In the patient who achieved only partial obliteration, there was a sac 13 mm in size, and there was no change in the 1-year follow-up angiography. In the patient with segmental occlusion, the cause could not be determined. The clinical outcome was modified Rankin Scale 0 in all patients. Conclusion : Our preliminary study using FDD to treat hemodynamically unstable unruptured VADA showed that FDD is safe and effective. Our study has limitations in that the number of cases is small, and it is not a prospective study. However, we believe that the study contributes to evidence regarding the safety and effectiveness of FDD in the treatment of unruptured VADA.

In Vivo Artificial Parthenogenetic Treatments on Live Silkworm Moth, Bombyx mori Can Induce Higher Parthenogenesis (살아있는 누에 나방(Bombyx mori)에 대한 인공적 단위 발생 처리의 단위 발생란 유발 촉진 효과)

  • Bae, Hee Eun;Lee, Yoon Kyung;Park, So Hyun;Lee, Seul-bi;Lee, Sang Mong
    • Journal of Life Science
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    • v.29 no.2
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    • pp.272-278
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    • 2019
  • The silkworm performs sexual reproduction for the production of its healthy offsprings from generations to generations. Parthenogenesis in the silkworm, Bombyx mori acquires immense use in the development of outstanding homozygouse lines with higher viability, hybrid vigour, combining ability and less phenotypic variability, and it can serve as a powerful tool in controlling sex of the offsprings as well as a useful tool in selection of breeding schemes. However, naturally occuring parthenogenesis in silkworm could not be found so far. Fortunately, artificial induction of parthenogenesis is possible in silkworm. So, it is very important to find out novel methods for induction of parthenogenesis. We investigated to attempt to get a novel parthenogenetic method. Accordingly, parthenogenetic studies on between unfertilized in vivo ovarian eggs of live silkworm moth(novel) and unfertilized in vitro ovarian eggs(conventional) taken out from live silkworm moth were investigated by hot water ($46^{\circ}C$), hot air ($46^{\circ}C$) and low temperature ($0^{\circ}C$ and $-20^{\circ}C$) treatments. The best ratio of parthenogenetic eggs was obtained with in vivo ovarian eggs of live silkworm moth rather than with in vitro ovarian eggs taken out from live silkworm moth in all the treatments. The optimum exposure time absolutely depended upon the temperatures of treatments and the forms of in vivo or in vitro ovarian eggs. From these results, we expect that in vivo artificial parthenogenetic treatments on live silkworm moth will be useful for the higher induction of parthenogenesis in the silkworm, B. mori.

Prevalence of enteropathogens in the feces from diarrheic Korean native cattle in Gwangju area, Korea (광주지역 한우 분변 내 설사병 병원체 조사)

  • Koh, Ba-Ra-Da;Kim, Hyo-Jung;Oh, A-Reum;Jung, Bo-Ram;Park, Jae-Sung;Lee, Jae-Gi;Na, Ho-Myoung;Kim, Yong-Hwan
    • Korean Journal of Veterinary Service
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    • v.42 no.2
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    • pp.93-112
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    • 2019
  • Calf diarrhea is a common disease in young claves and is still a major cause of productivity and economic loss in livestock farms. Fecal samples from Korean native cattle (n=100) with diarrhea from 64 farms in Gwangju area, Korea from september 2017 to December 2018 were examined for shedding of important protozoan parasitic, viral and bacterial pathogens using culture, rapid test kit and PCR methods. Of 57 (89.1%) of the 64 Korean native cattle farms examined had samples infected with at least one of the investigated pathogens. Among 100 fecal samples, 88 samples were positive for at least one the twelve pathogens and 51 samples were simultaneously positive for two or more pathogens by culture and PCR assay. Bovine group A rotavirus (BRV) was the most common pathogen, found in 43/100 (43.0%) samples on 32/64 (50.0%) farms. Subsequently, kobuvirus (30.0%), pathogenic E. coli (29.0%), bovine parvovirus (17.0%), Giardia spp. (13.0%), Eimeria spp. (10.0%), Clostridium perfringens type A (8.0%), bovine torovirus (8.0%), bovine viral diarrhea virus (6.0%), bovine coronavirus (5.0%), bovine norovirus (2.0%) and Cryptosporidium spp. (2.0%) were detected. Nebovirus, kırklareli virus, bovine adenovirus, Salmonella spp. and intestinal parasites were not detected. Of the 72 calves sampled in this age group, 64 (88.9%) samples were positive for at least one enteropathogen. BRV was identified in 34/72 (47.2%) samples from 27/48 (56.3%) farms. Subsequently, pathogenic E. coli (30.6%), kobuvirus (29.2%), BPaV (22.2%), Giardia spp. (15.3%), Eimeria spp. (9.7%), BVDV (6.9%), Cl. perfringens type A (6.9%), BCoV (4.6%) and Cryptosporidium spp. (2.8%) were detected in fecal samples. A total of ninety-six strains of E. coli were isolated from one hundred fecal samples collected from Korean native cattle with diarrhea. The presence of stx1, stx2, eaeA, LT, STa, STb, ehxA, saa, F4, F5(K99), F6, F17, F18 and F41 genes in the isolates was investigated by PCR. Out of ninety-six E. coli isolates screened for specific genes, 30 strains E. coli were identified to harbor shiga toxin-producing E. coli (STEC) 7 (7.3%), enterohemorrhagic E. coli (EHEC) 8 (8.3%), enteropathogenic E. coli (EPEC) 6 (6.3%), enterotoxigenic E. coli (ETEC) 2 (2.1%) and STEC/ETEC hybrid 7 (7.3%). This study provides epidemiological estimates of the prevalence of Korean native cattle's enteropathogens in Gwangju area, Korea, which would be used for cattle farmers and veterinarians to select appropriate therapeutic method.

The Experimental Assessment of Influence Factors on KLS-1 Microwave Sintering (한국형 인공월면토(KLS-1) 마이크로파 소결에 미치는 영향인자에 관한 실험적 연구)

  • Jin, Hyunwoo;Lee, Jangguen;Ryu, Byung Hyun;Shin, Hyu-Soung;Kim, Young-Jae
    • Journal of the Korean Geotechnical Society
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    • v.37 no.2
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    • pp.5-17
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    • 2021
  • The Moon has been an attractive planet as an outpost for deep space exploration since He-3 and water ice which can be used as energy resources were discovered. In-Situ Resource Utilization (ISRU) construction material fabrication method is required for sustainable space planet exploration. In this paper, the possibility of microwave sintering technology for construction material fabrication was evaluated using lunar regolith that can be easily collected from the Moon surface. Experimental assessment of the influence factors on microwave sintering was conducted using a hybrid sintering system for efficient processing. The heat distribution in the furnace was observed using thermal paper that is coated with a material formulated to change color when exposed to heat. Based on this result, sintered cylindrical KLS-1s with a diameter of 1 cm and a height of 2 cm were fabricated. Densities were measured for the sintered KLS-1s under rotating turntable conditions that have an effect of microwave dispersion. The more dielectrics were arranged, the more microwaves were dispersed reducing the heat concentration, and thus a uniformity of sintered KLS-1s was enhanced.

The Effect of COVID-19 on Academic Satisfaction with Online Lecture Types and Contents -Perspectives of the Domestic and Foreign University Students- (코로나19로 인한 온라인 강의 형태와 콘텐츠가 학업 만족도에 미치는 영향 -국내외 대학생의 관점에서-)

  • Jo, Ji-Soo;Bae, Jeong-In
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.22 no.3
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    • pp.643-650
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    • 2021
  • The purpose of this study was to evaluate the impact of lecture content on the overall academic satisfaction in non-contact online classes. The study was conducted using an online survey of 107 university students attending metropolitan, local and foreign universities for a week from August 25th, 2020 to September 2nd, 2020. The analysis methods used included descriptive statistics and chi-square distribution, Fisher's exact test, linear by linear association, and logistic regression. The result of the study showed a significant decrease in Junior by 0.025 times compared to Senior (p<.05). Furthermore, a significant decrease in the impact of recorded lectures by 0.036 times compared to a hybrid of face-to-face and online lectures (p<.05). Compared to the response 'No', the number of student's responses of 'Yes' increased significantly by 31.358 times (p<.05). Additionally, a significant increase was seen in teaching methods by 19.709 times, and academic satisfaction by 7.989 times(p<.05). In conclusion, the results imply that the quality of lecture content is also important to improve the student's satisfaction with school life, but overall management is required in the areas of appropriate teaching methods, appropriate tuition, and evaluation methods.

Reduction of VOCs and the Antibacterial Effect of a Visible-Light Responsive Polydopamine (PDA) Layer-TiO2 on Glass Fiber Fabric (Polydopamine (PDA)-TiO2 코팅 유리섬유 직물을 이용한 VOCs의 저감 성능 및 항균성 연구)

  • Park, Seo-Hyun;Choi, Yein;Lee, Hong Joo;Park, Chan-gyu
    • Journal of Environmental Health Sciences
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    • v.47 no.6
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    • pp.540-547
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    • 2021
  • Background: Indoor air pollutants are caused by a number of factors, such as coming in from the outside or being generated by internal activities. Typical indoor air pollutants include nitrogen dioxide and carbon monoxide from household items such as heating appliances and volatile organic compounds from building materials. In addition there is carbon dioxide from human breathing and bacteria from speaking, coughing, and sneezing. Objectives: According to recent research results, most indoor air pollution is known to be greatly affected by internal factors such as burning (biomass for cooking) and various pollutants. These pollutants can have a fatal effect on the human body due to a lack of ventilation facilities. Methods: We fabricated a polydopamine (PDA) layer with Ti substrates as a coating on supported glass fiber fabric to enhance its photo-activity. The PDA layer with TiO2 was covalently attached to glass fiber fabric using the drop-casting method. The roughness and functional groups of the surface of the Ti substrate/PDA coated glass fiber fabric were verified through infrared imaging microscopy and field emission scanning electron microscopy (FE-SEM). The obtained hybrid Ti substrate/PDA coated glass fiber fabric was investigated for photocatalytic activity by the removal of ammonia and an epidermal Staphylococcus aureus reduction test with lamp (250 nm, 405 nm wavelength) at 24℃. Results: Antibacterial properties were found to reduce epidermal staphylococcus aureus in the Ti substrate/PDA coated glass fiber fabric under 405 nm after three hours. In addition, the Ti substrate/PDA coated glass fiber fabric of VOC reduction rate for ammonia was 50% under 405 nm after 30 min. Conclusions: An electron-hole pair due to photoexcitation is generated in the PDA layer and transferred to the conduction band of TiO2. This generates a superoxide radical that degrades ammonia and removes epidermal Staphylococcus aureus.

A Study on Optimization of Perovskite Solar Cell Light Absorption Layer Thin Film Based on Machine Learning (머신러닝 기반 페로브스카이트 태양전지 광흡수층 박막 최적화를 위한 연구)

  • Ha, Jae-jun;Lee, Jun-hyuk;Oh, Ju-young;Lee, Dong-geun
    • The Journal of the Korea Contents Association
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    • v.22 no.7
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    • pp.55-62
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    • 2022
  • The perovskite solar cell is an active part of research in renewable energy fields such as solar energy, wind, hydroelectric power, marine energy, bioenergy, and hydrogen energy to replace fossil fuels such as oil, coal, and natural gas, which will gradually disappear as power demand increases due to the increase in use of the Internet of Things and Virtual environments due to the 4th industrial revolution. The perovskite solar cell is a solar cell device using an organic-inorganic hybrid material having a perovskite structure, and has advantages of replacing existing silicon solar cells with high efficiency, low cost solutions, and low temperature processes. In order to optimize the light absorption layer thin film predicted by the existing empirical method, reliability must be verified through device characteristics evaluation. However, since it costs a lot to evaluate the characteristics of the light-absorbing layer thin film device, the number of tests is limited. In order to solve this problem, the development and applicability of a clear and valid model using machine learning or artificial intelligence model as an auxiliary means for optimizing the light absorption layer thin film are considered infinite. In this study, to estimate the light absorption layer thin-film optimization of perovskite solar cells, the regression models of the support vector machine's linear kernel, R.B.F kernel, polynomial kernel, and sigmoid kernel were compared to verify the accuracy difference for each kernel function.

Quantitative precipitation estimation of X-band radar using empirical relationship (경험적 관계식을 이용한 X밴드 레이더의 정량적 강우 추정)

  • Song, Jae In;Lim, Sanghun;Cho, Yo Han;Jeong, Hyeon Gyo
    • Journal of Korea Water Resources Association
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    • v.55 no.9
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    • pp.679-686
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    • 2022
  • As the occurrences of flash floods have increased due to climate change, faster and more accurate precipitation observation using X-band radar has become important. Therefore, the Ministry of Environment installed two dual-pol X-band radars at Samcheok and Uljin. The radar data used in this study were obtained from two different elevation angles and composed to reduce the shielding effect. To obtain quantitative rainfall, quality control (QC), KDP retrieval, and Hybrid Surface Rainfall (HSR) methods were sequentially applied. To improve the accuracy of the quantitative precipitation estimation (QPE) of the X-band radar, we retrieved parameters for the relationship between rainfall rate and specific differential phase, which is commonly called the R-KDP relationship; hence, an empirical approach was developed using multiple rain gauges for those two radars. The newly suggested relationship, R = 27.4K0.81DP, slightly increased the correlation coefficient by 1% more than the relationship suggested by the previous study. The root mean square error significantly decreased from 3.88 mm/hr to 3.68 mm/hr, and the bias of the estimated precipitation also decreased from -1.72 mm/hr to -0.92 mm/hr for overall cases, showing the improvement of the new method.

Collection of Philosophical Concepts for Video Games -Theory of Art in the Age of Artificial Intelligence by Shinji Matsunaga's The Aesthetics of Video Games (인간과 컴퓨터가 공유하는 인공적인 놀이에 관한 개념상자 -마쓰나가 신지의 『비디오 게임의 미학』이 체계화하는 인공지능시대의 예술과 유희 이론)

  • Kim, Il-Lim
    • Journal of Popular Narrative
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    • v.26 no.4
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    • pp.215-237
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    • 2020
  • This paper is written to introduce and review Shinji Matsunaga's The Aesthetics of Video Games which published in Japan in 2018. Shinji Matsunaga has studied video games from a philosophical and aesthetic perspective. In The Aesthetics of Video Games, he took video games as a hybrid form of traditional games. Shinji Matsunaga particularly notes that video games can design human behaviors and experiences. From this point of view, he tries to construct a theoretical framework that will be able to describe the ways of signification in games and fiction respectively. In previous studies, video games have been mainly discussed in the context of cultural studies and entertainment culture in Japan. The Aesthetics of Video Games is distinguished from the previous studies in the following points. First, The Aesthetics of Video Games pioneered the method of studying video games in art theory. Second, it established various types of relationships with video games and traditional aesthetic concepts. Third, this book connects new concepts that emerged in the age of artificial intelligence to video games as an aesthetic action. Through this work, not only video games were discussed academically, but also the fields of aesthetics and art were expanded. The Aesthetics of Video Game is like a collection of philosophical concepts for video games. Through this book, it can be said that the path for artificial intelligence to approach human secrets is closer than before.

A Study on the Perception of University Librarians on RDA Adoption: Focusing on Interviews with University Librarians (RDA 도입에 대한 사서의 인식 연구 - 대학도서관 사서와의 면담을 중심으로 -)

  • Lee, Sung-Sook
    • Journal of the Korean BIBLIA Society for library and Information Science
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    • v.33 no.3
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    • pp.239-265
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    • 2022
  • The purpose of this study is to examine the status of RDA adoption in Korea and the perception of university librarians on RDA adoption. For this purpose, the adoption status of two libraries that adopted RDA among domestic libraries was analyzed. In addition, interviews were conducted with eight university librarians, and narrative responses related to the adoption of RDA were collected and analyzed. As a result of the interview survey, the research participants recognized that the concept of RDA is very difficult and abstract, there are few implementation cases where RDA is applied, and that it would be very difficult to adopt RDA due to the personnel and budget conditions of the local library. The RDA adoption method recognized by the research participants is to improve RDA awareness, conduct RDA education, prepare guidelines for constructing hybrid bibliographic records when RDA is adopted, operate an RDA pilot institution, and establish a performance model. In addition, research participants need coordination with companies for implementation, prefer to change a specific point in time rather than batch retroactive conversion, discover success stories, establish RDA-related online channels, build and utilize national authority DB, and use the national budget and system support. In this study, based on the research results, a plan to adopt RDA for university libraries in Korea was presented.