• 제목/요약/키워드: human subjects

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서열환경하에서의 전투복착용이 체온조절에 미치는 영향 (The Influence of Wearing Army Combat Uniform on the Thermal Responses in Heat Environment)

  • 김태규;조호현
    • 한국의류산업학회지
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    • 제16권1호
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    • pp.167-174
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    • 2014
  • The physical properties of textile materials and thermal physiological responses of the human subjects were evaluated with 4 different types of the army combat uniforms including US, German, Korean and general uniforms for this study. 8 male adults were used as the human subjects and the tests were done in the environmental chamber that was $25{\pm}0.1^{\circ}C$ of temperature, $65{\pm}5%$ of relative humidity and below 0.3 m/sec of air velocity. The test protocol consisted the rest period for 20 min., the exercise period for 20 min., the rest period for 20 min., the exercise period under wind condition for 20 min., and the recovery period for 20 min. The human subjects walked with 4.5 km/hr for 10 min., ran 7.5 km/hr for 10 min. during the first exercise period and walked and ran with the same speeds under 3.5 m/sec of the air velocity that simulated outdoor condition during the second exercise period. The test results of the study were as follows; The wind condition affected the skin and microclimate temperature of the human subjects lower compared to without wind condition, but had insignificant effect on the humidity control. The low air permeability of Korean uniform caused blocking the elimination of the humidity from the body and the regulation of body temperature. However, Korean uniforms could be the excellent one with the designs considering the ventilation of the uniforms and the textile fabrics with better air permeability.

New Haplotypes of the ATP Synthase Subunit 6 Gene of Mitochondrial DNA are Associated with Acute Lymphoblastic Leukemia in Saudi Arabia

  • Yacoub, Haitham Ahmed;Mahmoud, Wael Mahmoud;El-Baz, Hatim Alaa-Eldeen El-Din;Eid, Ola Mohamed;El-Fayoumi, Refaat Ibrahim;Mahmoud, Maged Mostafa;Harakeh, Steve;Abuzinadah, Osama H.A.
    • Asian Pacific Journal of Cancer Prevention
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    • 제15권23호
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    • pp.10433-10438
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    • 2015
  • Background: Acute lymphoblastic leukemia (ALL) is the most common cancer diagnosed in children and represents approximately 25% of cancer diagnoses among those younger than 15 years of age. Aim and Objectives: This study investigated substitutions in the ATP synthase subunit 6 gene of mitochondrial DNA (mtDNA) as a potential diagnostic biomarker for early detection and diagnosis of acute lymphoblastic leukemia. Based on mtDNA from 23 subjects diagnosed with acute lymphoblastic leukemia, approximately 465 bp of the ATP synthase subunit 6 gene were amplified and sequenced. Results: The sequencing revealed thirty-one mutations at 14 locations in ATP synthase subunit 6 of mtDNA in the ALL subjects. All were identified as single nucleotide polymorphisms (SNPs) with a homoplasmic pattern. The mutations were distributed between males and females. Novel haplotypes were identified in this investigation: haplotype (G) was recorded in 34% in diagnosed subjects; the second haplotype was (C) with frequency of 13% in ALL subjects. Neither of these were observed in control samples. Conclusions: These haplotypes were identified for the first time in acute lymphoblastic leukemia patients. Five mutations able to change amino acid synthesis for the ATP synthase subunit 6 were associated with acute lymphoblastic leukemia. This investigation could be used to provide an overview of incidence frequency of acute lyphoblastic leukemia (ALL) in Saudi patients based on molecular events.

한국의 간호교육과정 경향과 전망 (The trend of Current Nursing Curriculum in Korea and it's perspectives for the future)

  • 서문자
    • 한국간호교육학회지
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    • 제3권
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    • pp.46-58
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    • 1997
  • This review article provides the trend of current nursing curriculum of todays in Korea and its perspectives. This article reviewed 5 aspects of the current nursing curriculum for the undergraduate program, those are the (1)educational philosophy and believes (2)the nursing concepts revealed in the current nursing curriculum (3)the educational goals and objectives (4)the framework of nursing curriculum (5)the syllabus and credit hours. The common nursing concepts in the current nursing curriculum are Nursing, Human being, Environment/society, Health, Nursing science. The examplary vertical concepts composing of the current nursing curriculum are nursing process, life styles and the horizontal concepts are client, health promotion /recovery /maintenance, leadership, and research. The common subjects composing of the nursing syllabus are the introductory subjects(nursing history, nursing professionalism, foundamental nursing), and the supportive subjects (communication, human relationship, human growth and development, health education, etc) and nursing research, the intrductory basic sciences (anatomy, physiology etc.), and the major nursing subjects (adult nursing, child nursing, maternity nursing, psychiatric nursng, community nursing, nursing administration.) In order to have more advanced nursing education, the suggestions were provided as follows : (1) It is necessary to have revision and evaluation of the process and the structure of the current nursing curriculum periodically. (2) The concept of health promotion for all human being should be integrated into the nursing curriculum. (3) The nursing education program should be unified into baccalauliate level to get one type of nurse-registration system. (4) The nursing courses will need to provide the necessary contemporary Informations to allow the nurses to fuction efficiently in this rapidly changing era. (5) The use of new technology in nursing education is necessary to expand nursing education more.

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비정격(脾正格) 자침이 정상 성인 맥파(脈波) 변화에 미치는 영향 (The Effects of Sa-Am Spleen-tonifying Acupuncture on Radial Pulse in Healthy Human Subjects)

  • 윤광식;이현
    • Journal of Acupuncture Research
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    • 제30권4호
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    • pp.1-14
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    • 2013
  • Objectives : The purpose of this study is to investigate the effects of Sa-Am spleen-tonifying acupuncture on radial pulse in healthy human subjects. Methods : Forty healthy human subjects participated in this study, divided into acupuncture group and control group. Radial pulse was measured by 3 dimensional pulse imaging system(DMP-3000) before, right after, 30 minutes after and 60 minutes after acupuncture in the acupuncture group. The subjects in the control group didn't received acupuncture but took a rest and then the radial pulse was measured at the same time points as the acupuncture group. The parameters were analyzed by gender, measuring location, and measuring time point. However the time related parameters exceptionally were analyzed without distinction of measuring location. Results : 1. T, variance of period, T2/T, T4/T, (T-T4)/T, T4/(T-T4), and W significantly changed after acupuncture. 2. Pressure, amplitude of H1, amplitude of H2, Amplitude of H4 and pulse energy significantly changed after acupuncture. 3. Pulse area, systolic pulse area and diastolic pulse area significantly changed after acupuncture. 4. Elasticity, AIx and AIx/HR significantly changed after acupuncture. Conclusions : The effect of Sa-Am spleen-tonifying acupuncture in healthy human may be observed on time, amplitude, pulse area and augmentation index. Further studies on the effects of Sa-Am acupuncture using radial pulse are needed.

고추가 정상인의 혈장 gastrin 농도에 미치는 영향 (Effect of Red Popper on Plasma Gastrin Concentration in Normal Human Subjects)

  • 김명석;권경옥;이윤렬;김정진;최현
    • The Korean Journal of Physiology
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    • 제16권1호
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    • pp.57-61
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    • 1982
  • This study was conducted to investigate the effect of ingestion of rice meal with red pepper(Capsicum annuum) as a seasoning upon the plasma gastrin concentration of normal human subjects in Korea. Thirteen normal human subjects including male and female(mean age: 21 years, range: $20{\sim}24\;years$) were studied. After an overnight(about 15 hrs) fast each subject ingested a test meal and a control meal on different days. The test meal consisted of 250 g toiled rice, 250 ml radish soup containing red pepper(dried powder, 3 g), 50 g vegetables and 200 ml barley tea, corresponding to 7.0 g protein, 9.0 g fat and 82 g carbohydrate and the control meal consisted of the same amount as the test meal except that the radish soup was supplied without red pepper. The venous blood samples were drawn before and after the ingestion of meals at the following times: -30, 0, 15, 30, 45, 60, 90, and 120 min for the measurement of plasma gastrin concentration by means of radioimmunoassay. 1) Plasma gastrin concentration in response to the ingestion of control meal without red pepper increased significantly compared with the concentration in fasting state. 2) The increase of plasma gastrin concentration after the ingestion of test meal(containing red pepper) was significantly higher than that after the control meal. It is inferred from the above mentioned results that the ingestion of red pepper as a seasoning has a stimulatory influence on gastrin release in normal human subjects.

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A Survey on the Awareness of Human Milk Bank in Korean Female Health Care Providers

  • Hahn, Won-Ho;Song, Joon-Hwan;Park, Suyeon;Kang, Nam Mi;Ahn, Sukhee;Song, Seunghyun
    • Perinatology
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    • 제28권1호
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    • pp.11-19
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    • 2017
  • Objective: Human milk bank is known as best alternative option for sick infants. However, only two human milk banks (HMBs) are working in Korea. In the present study, we evaluated the awareness on the HMB in female health care provider to find out the issues that would help facilitating HMB establishment in Korea. Methods: The survey questionnaire was developed by a team composed with neonatologists, obstetricians, nurses, nutritionists, and health care specialists. The survey was performed for female health care workers in Soon Chun Hyang Cheonan Hospital between March and June in 2016. Eighty-eight of 110 questionnaires were collected and the results were analyzed. Results: Most of subjects were found to have correct knowledge on the breast milk feeding. However, only 49% of subjects had awareness of the presence of HMB. Unfortunately, less than half of them could get information about HMB by official way including mass media. In addition, 76% of subjects were found not to want to use HMB. Most important reason was found as a concern on the safety of donor milk including life style of donors, infection controls, and possible nutritional loss of banked milk. Conclusion: The purpose and function of HMB was not widely educated and it seems to be one of most important reasons why women have negative concept about HMB in Korea. Thus, further study is warranted with more numbers of subjects after active public education about the HMB.

성인기 애착 안정성에 관한 연구 -이성 및 부모에 대한 애착과 부모 부양 의무감을 중심으로- (A Study of Adult Attachment Security: romantic attachment, and attachment and filial obligation to parents)

  • 조윤주
    • 한국생활과학회지
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    • 제18권1호
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    • pp.75-92
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    • 2009
  • The purposes of this study are to investigate the relationship between university students' romantic and parent attachment in attachment security and to examine the relationship among romantic attachment, parent attachment and filial obligation for generational transition. Major results of this study are as follows: first, the level of attachment anxiety in female students is higher than male students. 25.1% of the subjects is classified into a secure type and 74.9% is classified as an insecure type. Second, female subjects feel strong attachment to their mothers than male subjects. Third, romantic attachment of female students is related to attachment to their fathers. Fourth, male subjects feel more filial obligation than female subjects. Finally, their romantic and parent attachment are positively related to their filial obligation. Variables that explain male students' filial obligation are ones of 'giving economic aid to parent' and 'the extent of attachment to their fathers'. A variable accounting for female students' filial obligation is 'the extent of attachment to their mothers'.

의복환경학 분야의 국내 연구동향 (Analytical Study on Research Trends of Clothing Comfort Reported in Korean Journals)

  • 권수애
    • 한국생활과학회지
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    • 제24권4호
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    • pp.541-554
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    • 2015
  • In this research in order to grasp the recent research trends of clothing comfort in Korea, 584 theses have been analyzed about the forms, contents and subjects of their researches which have been published in four Korean Journals from 2000 to 2012. The results are as follows: Many of the research contents were on the clothing comfort and environmental adaptation clothes in all journals. Handle, skin temperature, clothing pressure and working clothes showed the highest frequency ln the key words. The review studies were the fewest, and experimental or survey researches were largely conducted. The research forms showed the significant differences according to the research contents. The subjects were largely focused on those aged from 18 to 29, and among the research subjects on clothing comfort, female were more than male. However, in the researches on clothing quantity and clothes wearing conditions, many of them were the studies whose subjects were both men and women. The male and old subjects increased more and more. The number of the theses in the field of clothing environmentology showed the gradually increasing tendency. The most rates were the theses on clothing comfort, but as the number of those on environment adaptation clothes increased more and more, the research contents in the two fields showed much the same. Though the attention to aging and smart clothes is increasing, the research on this is very few. Therefore, it is thought that the study on this field will have to be conducted actively.

흡연과 Carotenoid 함유 식품 섭취빈도에 따른 지질과산화 및 항산화능 비교 (Effect of Smoking and Carotenoid-rich Food Consumption on Lipid Peroxidation and Antioxidant Status)

  • 김유경;천종희
    • Journal of Nutrition and Health
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    • 제38권10호
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    • pp.836-846
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    • 2005
  • This study was performed to determine the effect of carotenoid-rich food consumption and smoking on the lipid peroxidation and antioxidant status in human. The subjects consisted of the health 210 middle-aged adults who visited health care center in the Inha University hospital. The blood and urine samples of the subjects were taken to analyze serum lipid profiles, plasma TBARS, total antioxidant status (TAS) and urinary 8-isoprostanes concentration. The anthropometric indices of the subjects were measured. The nutritional intake and the frequency of carotenoid-rich food consumption was determined by semi-quantitative food frequency questionnaire survey. HDL-cholesterol level of the smoking subjects was significantly lower than that of the non-smoking subjects in men. In the analysis of the carotenoid-rich food consumption, the frequency of pepper and tomato consumption of the non-smoking subjects was significantly higher than that of the smoking subjects in men. In women, the Sequency of pear and peach consumption of the non-smoking subjects was significantly higher than that of the smoking subjects. HDL-cholesterol level of the high carotenoid rich food consumption group was significantly higher than that of medium and low group in women. TAS of the high carotenoid rich food consumption group was significantly higher than that of medium and low group. In conclusion, carotenoid intakes seemed to be effective to reduce lipid peroxidation and increase antioxidant status in the body. The frequency of the carotenoid-rich food consumption seemed to be lower in the smokers than in the non-smokers. However, further researches consisted of large-scaled and randomized clinical trials are required to determine whether carotenoids have any other beneficial effect in human. (Korean J Nutrition 38(10): 836$\sim$846,2005)

Effect of a 12-week weight management program on the clinical characteristics and dietary intake of the young obese and the contributing factors to the successful weight loss

  • Lee, AeJin;Jeon, Kyeong Jin;Kim, Hye-Kyeong;Han, Sung Nim
    • Nutrition Research and Practice
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    • 제8권5호
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    • pp.571-579
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    • 2014
  • BACKGROUND/OBJECTIVES: The objectives were to investigate the effect of a 12-wk intervention with behavioral modification on clinical characteristics and dietary intakes of young and otherwise healthy obese and to identify factors for successful weight loss. The goal was to lose 0.5 kg per week by reducing 300-500 kcal/day and by increasing physical activities. SUBJECTS AND METHODS: Forty four obese subjects (BMI > 25) and 19 normal weight subjects (BMI 18.5-23) finished the 12-week intervention. Obese subjects participated in 5 group educations and 6 individual counseling sessions. Normal weight subjects attended 6 individual counseling sessions for evaluations of dietary intake and exercise pattern. Anthropometric and clinical characteristics and 3-day dietary records were evaluated at baseline and week12. RESULTS: Weight and serum triglyceride and free fatty acid concentrations in obese group decreased significantly with intervention. Intakes of energy, fat, and cholesterol decreased significantly in the obese. Active participation, realistic weight loss goal setting, and weight gain after high school graduation not during childhood were identified as key factors for successful weight loss. CONCLUSIONS: The 12-week intervention with behavioral modification resulted in reduced energy and fat intakes and led to significant weight loss and improvements of clinical characteristics in the obese. The finding that those who became obese during childhood lost less weight indicates the importance of 'early' intervention.