• Nuclear Engineering and Technology
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• v.36 no.5
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• pp.430-449
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• 2004

A quantitative model for a control system that integrates human operators, systems, and their interactions is developed based on discrete functions. After identifying the major entities and the key factors that are important to each entity in the control system, a quantitative analysis to estimate the recovery failure probability from an abnormal state is performed. A numerical analysis based on assumed values of related variables shows that this model produces reasonable results. The concept of 'relative sensitivity' is introduced to identify the major factors affecting the reliability of the control system. The analysis shows that the hardware factor and the design factor of the instrumentation system have the highest relative sensitivities in this model. T도 probability of human operators performing incorrect actions, along with factors related to human operators, are also found to have high relative sensitivities. This model is applied to an analysis of the TMI-2 nuclear power plant accident and systematically explains how the accident took place.

• Journal of Microbiology
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• v.38 no.4
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• pp.255-259
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• 2000

For rapid and sensitive measurement of antiviral activities, application of a recombinant virus containing firefly luciferase gene was attempted. Recombinant human cytomegalovirus (HCMV) containing luciferase gene driven by HCMV late gene pp28 promoter (HCMV/pp28-luc) was used to test the antiviral activities of three known compounds and the result was compared with results from the conventional plaque assay for measuring the production of infectious viruses. When human fibroblast cells were infected with HCMV/pp28-luc, luciferase activity was observed at 2 days after infection and reached maximum at 6 days after infection, whereas the production of infectious virus was maximal at 4 days after infection. The antiviral activities of ganciclovir, acyclovir, and papaverine were measured in HFF cells infected with HCMV/PP28-luc and the luciferase activity was compared with the infectious virus titers. Luciferase activity decreased as the concentration of ganciclovir or papaverine increased, while there was a slight decrease in luciferase activity with acyclovir. The level of the decrease in Luciferase activity was comparable to the level of decrease in the production of infectious virus. Therefore, the antiviral assay using recombinant virus HCMV/pp28-luc resulted in sensitivity similar to the conventional plaque assay with a significant reduction in assay time.

• Proceedings of the Korean Institute Of Construction Engineering and Management
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• 2006.11a
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• pp.473-477
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• 2006

In domestic construction site, convenient facilities for worker are much lacking up to now. These things exert negative influences in the occurrence of construction disaster because a safety-aware of worker-self is been lacking ultimately, and 3D(Dirty Dangerous Difficult) evasion phenomenon for construction site spreads more to workers and actuality that is going through manpower problems may be heavier. This research applied sensitivity safety cultural institutions that make aware of worker's sensitivity in spot to search solution way of these problems from resource of human original nature. By the result, there were affirmative sides that sensitivity safety cultures facilities make created a safety-aware during work to worker-self. Also, these facilities gave as member of a constituent by workers, it examined that become many helps in operation efficiency.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2002.05a
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• pp.353-358
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• 2002

Human's vision is mostly confined to the area in the front and we, humans heavily depend on the sense of hearing to gather information in areas out of our sight. Thus, the virtual reality system consisting of the 3D sound effect gives the user a much better sense of reality than the system without the sound effect. Virtual 3D sound technology has mainly been researched with binaural system. The conventional binaural sound systems reproduce the desired sound at two arbitrary points using two channels in 3-D space. Head movement of listener might be change the nominal acoustic transfer function and deteriorate the performance of 3D sound system based on loudspeakers that needs a crosstalk canceller. In this paper, low kinds of sensitivity functions of sphere HRTF are derived to investigate the effect of head movement on HRTF in 3D sound system. Changes of HRTF caused by rotational and translational motion of head are obtained as we calculate the derivatives of HRTF with respect to angle and distance.

• Journal of the Korean institute of surface engineering
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• v.55 no.6
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• pp.342-352
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• 2022

Purine catabolite screening enables reliable diagnosis of certain diseases. In this regard, the development of a facile detection strategy with high sensitivity and selectivity is demanded for point-of-care applications. In this work, the simultaneous detection of uric acid (UA), xanthine (XA), and hypoxanthine (HX) was carried out as model purine catabolites by surface-enhanced Raman Spectroscopy (SERS). The detection assay was conducted by employing high-aspect ratio Au nanopillar substrates coupled with in-situ Au electrodeposition on the substrates. The additional modification of the Au nanopillar substrates via electrodeposition was found to be an effective method to encapsulate molecules in solution into nanogaps of growing Au films that increase metal-molecule contact and improve substrate's sensitivity and selectivity. In complex solutions, the approach facilitated ternary identification of UA, XA, and HX down to concentration limits of 4.33 𝜇M, 0.71 𝜇M, and 0.22 𝜇M, respectively, which are comparable to their existing levels in normal human physiology. These results demonstrate that the proposed platform is reliable for practical point-of-care analysis of biofluids where solution matrix effects greatly reduce selectivity and sensitivity for rapid on-site disease diagnosis.

• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.21 no.10
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• pp.883-889
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• 2011

The brand sound of vehicle diesel engine is recently one of the important advantage strategies in the automotive company. Because various noise components masked under high frequency level can be audible in quieter driving situation. Many researches have been carried out for subjective and objective assessments on vehicle sounds and noises. In particular, the interior sound quality has been one of research fields that can give high quality feature to vehicle products. Vehicle interior noise above 500 Hz is usually controlled by sound package parts. The materials and geometries of sound package parts directly affect on this high frequency noise. This paper describes the sound quality evaluation method for the vehicle diesel engine noise to establish objective criteria for sound quality assessment. Considering the sensitivity of human hearing to impulsive sounds such as diesel noise, the human auditory mechanism was simulated by introducing temporal masking in the time domain. Furthermore, each of the human auditory organs was simulated by computer codes, providing reasonable analytical explanations of typical human hearing responses to diesel noise. This method finally provides the sound quality index of vehicle diesel engine noise that includes high frequency intermittent offensive sounds caused by impacting excitations of combustion and piston slap.

• Journal of the Korean Society for Precision Engineering
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• v.32 no.11
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• pp.989-995
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• 2015

In the literature, various stochastic anomaly detection methods, such as limit checking and PCA-based approaches, have been applied to weld defect detection. However, it is still a challenge to identify meaningful defect patterns from very limited sensor signals of laser welding, characterized by intermittent, discontinuous, very short, and non-stationary random signals. In order to effectively analyze the physical characteristics of laser weld signals: plasma intensity, weld pool temperature, and back reflection, we first transform the raw data of laser weld signals into the form of event logs. This is done by multidimensional discretization and event-codification, after which the event logs are decoded to extract weld defect patterns by $Na{\ddot{i}}ve$ Bayes classifier. The performance of the proposed method is examined in comparison with the commercial solution of PRECITEC's LWM$^{TM}$ and the most recent PCA-based detection method. The results show higher performance of the proposed method in terms of sensitivity (1.00) and specificity (0.98).

• Journal of Industrial Technology
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• v.43 no.1
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• pp.25-31
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• 2023

Stretchable and flexible electronics that comply with dynamic movements and micromotion of the human tissues can enable real-time monitoring of physiologic signals onto the human skin and in the brain, respectively. Especially, gallium based liquid metal stretchable electronics can offer human-interactive biosensors to monitor various physiologic parameters. However, the liquid-like nature, surface oxidation and contamination by organic materials, and low biostability of the liquid metals have still limited the long-term use as bioelectronics. Here we introduced electrochemical deposition without oxidation pathways to overcome these practical challenges in liquid metal bioelectronics. CNT/PDDA composite with reduction way and PEDOT:BF₄ with oxidation way under organic solvent are suggested as rationally designed material engineering approaches. We confirmed that the structures with the soft, flexible, and stretchable liquid metal platform can successfully detect dopamine with a high sensitivity and selectivity, record neural signals including action potentials without scar formation, and monitor physiologic signals such as EMG and ECG.

• Journal of Biomedical Engineering Research
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• v.9 no.2
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• pp.149-152
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• 1988

From the analysis of proton NMR signals of human urine it is found that the signals corresponding to a phenolic compound of tyrosine are more frequently observed in cancer urine than in non-cancer urine. An effective reagent is obtained to detect the substance excreted in the urine and to find out a close connection with the result of the NMR analysis. An attempt is made to determine the reagent sensitivity and specificity for cancer diagnosis. The results of the attempt are respectively above 75% for both on an average.

• Journal of Biomedical Engineering Research
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• v.11 no.1
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• pp.19-24
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• 1990

A simple diffraction grating spectrometer is successfully utilized to distinguish the similar red colored sediments obstained from both of cancer and non-cancer urine reactions caused by the the previous developed reagent for the cancer diagnosis by examining their spectral absorption bands in order to improve its sensitivity and specficity. It is found that the cancer and non-cancer absorp- tion band regions lie between 4250 A and 4750 A and between 5250 A and 5400 A, respectively.