• Title/Summary/Keyword: human population

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STUDIES ON THE BIOLOGICAL HALF-LIVES OF TRITIUM RELEASED AT WOLSONG NUCLEAR POWER PLANTS

  • Kim, H.G.;Eum, H.M.;Cha, S.C.;Kim, M.C.
    • Journal of Radiation Protection and Research
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    • v.26 no.3
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    • pp.139-142
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    • 2001
  • The one of important parameter involved in the calculation of internal radiation dose to the human body is the biological half-life of the radionuclide. The biological half-life is population specific and may differ from one population group to another. So the effective half-life of tritium exposure based on urinal bioassay measurement of Wolsong Nuclear Power Plants was investigated and studied.

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Health Risk Assessment of Lead Exposure through Multi-pathways in Korea (납의 다경로 노출에 의한 건강위해성평가 : 우리 나라 일부 지역 성인들을 대상으로)

  • Chung, Yong;Hwang, Man-Sik;Yang, Ji-Yeon;Jo, Seong-Joon
    • Environmental Analysis Health and Toxicology
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    • v.14 no.4
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    • pp.203-216
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    • 1999
  • This paper describes a set of multi-pathway models for estimating health risk to lead. The models link concentrations of an environmental contaminant (lead) in air, water and food to human exposure through inhalation, ingestion, and dietary routes. Exposure is used as the foundation for predicting risk of health detriment within the population. The process of estimating exposure using often limited data and extrapolating to a large diverse population requires many assumption, inferences, and simplification. This paper is divided into four section. The first section provides lead contaminant levels on obtaining environmental concentration of air, tap water, and foods. The second section provides a discussion of exposure parameters and uncertainty associated predicting human health risk of contaminants. The third and fourth section illustrate lifetime average daily exposure (LADE) and excess cancer risk (ECR) based on exposure parameters. The relationship between concentration of lead in an environmental medium and human exposure is determined with pathway exposure factors (PEFs). The calculation of LADE and ECR is carried out using Monte-Carlo simulation with probability density function of exposure parameters. Examination of the result reveals that, for lead exposure, ingestion (food) is the dominant route of exposure rather than inhalation (air), and ingestion (tap eater).

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Epidemiological Features of Human Papillomavirus (HPV) Infection among Women Living in Mainland China

  • Li, Jing;Huang, Rong;Schmidt, Johannes E.;Qiao, You-Lin
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.7
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    • pp.4015-4023
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    • 2013
  • Cancer of the cervix is the third most common cancer in women worldwide, more than 85% of the cases occurring in developing countries such as China. In China, since a national cancer registry is already set up but with geographically limited data generated, the burden of cervical cancer is believed to be underestimated. High-risk human papillomavirus (HR-HPV) prevalence among women attending routine cervical cancer screening programs has been shown to correlate well with cervical cancer incidence rates based on independently obtained HPV prevalence data as well as findings for the worldwide cervical cancer burden. Therefore, reviewing data on HR-HPV prevalence in population-based screening studies and hospital-based case studies will be important in the context of better understanding the cervical cancer burden and for the evaluation of the potential impact of HPV vaccination in the country. With the advent of prophylactic vaccines, significant progress is likely to be made in cervical cancer prevention. This article reviews available data on the HPV epidemiology over a 12-year time period (2001-2012) in mainland China under different epidemiological aspects: by age group of study population, by ethnicity, by geographic area, as well as time period. The authors also review the potential acceptability of HPV vaccination among Chinese women.

Analysis of Unequal Distribution of Population Income in Indonesia

  • PRAWOTO, Nano;CAHYANI, Richa Dwi
    • The Journal of Asian Finance, Economics and Business
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    • v.7 no.7
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    • pp.489-495
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    • 2020
  • Income inequality is a problem that is not only faced by developing countries such as Indonesia, but also developed countries. The difference lies in the proportion of an inequality that occurs and the solution to the level of difficulty experienced. Thus, this study aims to empirically analyze the unequal distribution of population income in Java island, Indonesia, by including the human development index, open unemployment rate, foreign investment, and the degree of fiscal decentralization. The research model used in this study was multiple linear regression to analyze the panel data with a fixed-effect model approach. The results of the study showed that human development index, open unemployment rate, and the degree of fiscal decentralization had a positive and significant effect on income inequality in Java island. Meanwhile, foreign investment had a negative and insignificant effect on income inequality in Java. It is because the value of the investment is more invested in the capital-intensive sector. The government is expected to be more selective in accepting foreign investments that enter the country, especially in Java, and it should be labor-intensive investments. In addition, the government has to equalize locations for foreign investment without reducing good cooperation with these foreign investors.

Effects of persimmon leaf extracts on proteasome activity in HepG2 human liver cancer cells (감잎 추출물이 HepG2 인간 간암 세포의 proteasome 활성에 미치는 영향)

  • Kim, Soyoung;Yoon, Hyungeun
    • Korean Journal of Food Science and Technology
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    • v.51 no.4
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    • pp.393-397
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    • 2019
  • Proteasome inhibitors can promote apoptosis and cell cycle arrest in cancer cells by inhibition of nuclear factorkappaB ($NF-{\kappa}B$) activation. The purpose of this study was to investigate the effects of persimmon leaf extract (PSE) on proteasome activity in HepG2 human liver cancer cells. PSE treatment inhibited the proteasome activity and $NF-{\kappa}B$ activation in a dose-dependent manner in HepG2 human liver cancer cells (p<0.05). PSE treatment increased the population of cells in G2/M and sub-G1 phases. The results suggested that PSE is one of the candidate substances that may be developed into a proteasome inhibitor.