• 한국콘텐츠학회논문지
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• 제12권12호
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• pp.639-646
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• 2012

본 논문에서는 HP 컬러 레이저 프린터 기기의 출력물에 나타나는 Yellow Dots의 형태를 분석하고자, 각각 시간의 경과, 연과 월의 경과 그리고 동일한 기종에 따른 Yellow Dots의 특성을 실험하였다. 그 결과, 동일한 프린터기기의 출력물에서는 시간의 경과, 연과 월의 경과에서 나타나는 Yellow Dots의 형태가 동일한 것을 알 수 있었다. HP 컬러 레이저젯 프린터 기기에는 Xerox사에서 출시된 컬러 레이저젯 프린터기기와는 다르게 시간과 날짜 정보가 임베딩 되지 않았다는 것을 가정 할 수 있었다. 또한 시리얼 넘버가 다른 프린터기기에서는 유사하지만 다른 형태의 Yellow Dots가 나타나는 것을 알 수 있었으며, 이것은 프린터기기 구분에 있어 큰 도움이 된다. 마지막으로 실험에 사용된 모든 HP 컬러 레이저 프린터 기기들의 Yellow Dots를 분석한 결과, 동일한 패턴을 찾을 수 있었으며, 그 결과를 통하여 제조사를 파악 할 수 있었다. 향후 Yellow Dots 패턴을 해독하고 나아가 타 제조사의 Yellow Dots를 검출 및 분석하는 연구가 진행되어져야 한다.

• Asian-Australasian Journal of Animal Sciences
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• 제24권3호
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• pp.407-413
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• 2011

Effect of dietary protein and lipid levels on compensatory growth of juvenile olive flounder (Paralichthys olivaceus) was determined in suboptimal temperature ($13.4{\pm}1.42^{\circ}C$). Five hundred forty fish averaging 79.2 g were randomly distributed into 27 of 300 L flow-through tanks (20 fish/tank). Nine treatments were prepared in triplicate: fish were hand-fed with control (C) diet for 10 weeks (10WF-C); four fish groups were starved for 1 week and then fed with C, high protein (HP), high lipid (HL) and combined high protein and high lipid (HPL) diets for 9 weeks, referred to as 9WF-C, 9WF-HP, 9WF-HL, 9WF-HPL, respectively; and other four fish groups were starved for 2 weeks and then fed with C, HP, HL and HPL diets for 8 weeks, referred to as 8WF-C, 8WF-HP, 8WF-HL and 8WF-HPL, respectively. Weight gain and specific growth rate of fish in 9WF-HP, 9WF-HPL, 8WF-HP and 8WF-HPL treatments were higher than those of fish in 9WF-HL and 8WF-HL treatments. Feed efficiency of fish in 8WF-HP treatment was higher than that of fish in 9WF-C, 9WF-HL and 8WF-HL treatments. Protein efficiency ratio of fish in 10WF-C, 8WF-C, 8WF-HP and 8WF-HPL treatments was higher that that of fish in 9WF-HL and 8WF-HL treatments. Juvenile olive flounder subjected to 2-week feed deprivation could achieve full compensatory growth with dietary supplementation of protein or combined high protein and high lipid.

• IMMUNE NETWORK
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• 제8권3호
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• pp.90-97
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• 2008

Background: Hypersensitivity pneumonitis (HP) comprises a group of lung diseases resulting from repeated inhalation of various antigens such as Saccharopolyspora rectivirgula (SR). HP is categorized as a Th1 disease. Therefore, it has been suggested that IL-4, Th2 type cytokine, plays a protective role in the development of HP. However, the functional role of IL-4 in HP has not been extensively investigated in vivo. Therefore, we investigated the functional role of IL-4 in HP using IL-4 knockout (KO) mice. Methods: HP was induced by repeated exposure to SR in C57BL/6 (B6) and IL-4 KO (C57BL/6 background) mice. Results: IL-4 KO mice aggravated HP in terms of histological alteration, SR-specific immune responses, and inflammatory cell infiltration in the lungs compared with B6 mice. IL-4 KO mice produced high levels of IFN-${\gamma}$, TGF-${\beta}$ and TNF-${\alpha}$ in the lungs, whereas B6 mice showed the enhanced production of IL-4. Moreover, chemokines such as MIP-1${\alpha}$, MCP-1, and RANTES were highly expressed in IL-4 KO mice. IFN-${\gamma}$-secreting CD4, CD8 T cells, and neutrophils were enhanced in the bronchoalveolar lavage fluid (BALF) of IL-4 KO mice than those of B6 mice. The administration of recombinant(r) IL-4 restored these immunologic parameters in IL-4 KO mice. Conclusion: These results indicate that IL-4 plays a suppressive role in SR-induced HP by attenuating Th1-dominant immune responses.

• 한국축산식품학회지
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• 제29권3호
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• pp.317-324
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• 2009

In order to reduce the increased hardness of beef bulgogi due to hydrostatic pressure (HP), kiwifruit (Actinidia chinensis) was applied. To understand the changes of shear force in beef bulgogi with kiwifruit induced by HP, changes in chemical properties of myofibril (Mf) with 10% kiwifruit induced by HP were investigated. From the SDS-PAGE patterns of Mf with 10% kiwifruit, there was an observed increase in the degradation of myosin heavy chain (MHC) by HP (300-500 MPa) to that by 0.1 MPa. This result indicates that HP may enhance enzyme action from a kiwifruit for the degradation of MHC, and the similar phenomenon occurred in the beef bulgogi with kiwifruit induced by HP. The shear force of beef bulgogi without a kiwifruit induced by 400 and 500 MPa significantly increased compared to that by 0.1 MPa (p<0.05). However, in the beef bulgogi with 10% or 20% kiwifruit, the shear force induced by 400 or 500 MPa was similar or slightly lower than that by 0.1 MPa. Consequently, adding kiwifruit to bulgogi could reduce the hardness of HP-induced beef bulgogi due to the enzyme action in the kiwifruit accelerated by HP.

• Journal of Gastric Cancer
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• 제19권2호
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• pp.225-233
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• 2019

Purpose: Gastric adenocarcinoma of the fundic gland type (chief cell predominant type) (GA-FG-CCP) was first reported as a rare adenocarcinoma found in the normal fundic mucosa. Recent studies have proposed the possibility that GA-FG-CCPs were also generated in the atrophic mucosa after Helicobacter pylori (HP) eradication therapy. However, little is known on the endoscopic findings of GA-FG-CCP generated in the atrophic mucosa due to its extreme rarity. Materials and Methods: A total of 8 patients who underwent endoscopic submucosal resection and were diagnosed with GA-FG-CCP generated in the HP-uninfected mucosa (4 cases, HP-uninfected group) or HP-eradicated atrophic mucosa (4 cases, HP-eradicated group) were retrospectively analyzed, and their endoscopic findings, including magnifying endoscopy with narrow band imaging (M-NBI), and pathological features were compared. Results: While GA-FG-CCPs in the 2 groups displayed similar macroscopic appearance, M-NBI demonstrated that characteristic microvessels (tapered microvessels like withered branches) were specifically identified in the HP-eradicated group. Pathological investigation revealed that a decreasing number of fundic glands and thinned foveolar epithelium covering tumor ducts were thought to lower the thickness of the covering layer over tumor ducts in the HP-eradicated group. Moreover, dilation of vessels just under the surface of the lesions contributed to the visualization of microvessels by M-NBI. Conclusions: The change in background mucosa due to HP infection influenced the thickness of the covering layer over the tumor ducts and M-NBI finding of GA-FG-CCP.

• 대한약침학회지
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• 제22권2호
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• pp.102-108
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• 2019

Objectives: Esophageal squamous cell carcinoma (ESCC) is considered as a deadly medical condition that affects a growing number of people worldwide. Targeted therapy of ESCC has been suggested recently and required extensive research. With cyclin D1 as a therapeutic target, the present study aimed at evaluating the anticancer effects of doxorubicin (Dox) or Hypericum perforatum L. (HP) extract encapsulated in poly(lactic-co-glycolic acid) (PLGA) nanoparticles on the ESCC cell line KYSE30. Methods: Nanoparticles were prepared using double emulsion method. Cytotoxicity assay was carried out to measure the anti-proliferation activity of Dox-loaded (Dox NPs) and HP-loaded nanoparticles (HP NPs) against both cancer and normal cell lines. The mRNA gene expression of cyclin D1 was evaluated to validate the cytotoxicity studies at molecular level. Results: Free drugs and nanoparticles significantly inhibited KYSE30 cells by 55-73% and slightly affected normal cells up to 29%. The IC50 of Dox NPs and HP NPs was ~ 0.04-0.06 mg/mL and ~ 0.6-0.7 mg/mL, respectively. Significant decrease occurred in cyclin D1 expression by Dox NPs and HP NPs (P < 0.05). Exposure of KYSE-30 cells to combined treatments including both Dox and HP extract significantly increased the level of cyclin D1 expression as compared to those with individual treatments (P < 0.05). Conclusion: Dox NPs and HP NPs can successfully and specifically target ESCC cells through downregulation of cyclin D1. The simultaneous use of Dox and HP extract should be avoided for the treatment of ESCC.

• Korean Journal of Radiology
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• 제24권7호
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• pp.668-680
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• 2023

Objective: To compare multiparametric magnetic resonance imaging (MRI) features of intraductal carcinoma of the prostate (IDC-P) with those of prostatic acinar adenocarcinoma (PAC) and develop prediction models to distinguish IDC-P from PAC and IDC-P with a high proportion (IDC ≥ 10%, hpIDC-P) from IDC-P with a low proportion (IDC < 10%, lpIDC-P) and PAC. Materials and Methods: One hundred and six patients with hpIDC-P, 105 with lpIDC-P and 168 with PAC, who underwent pretreatment multiparametric MRI between January 2015 and December 2020 were included in this study. Imaging parameters, including invasiveness and metastasis, were evaluated and compared between the PAC and IDC-P groups as well as between the hpIDC-P and lpIDC-P subgroups. Nomograms for distinguishing IDC-P from PAC, and hpIDC-P from lpIDC-P and PAC, were made using multivariable logistic regression analysis. The discrimination performance of the models was assessed using the receiver operating characteristic area under the curve (ROC-AUC) in the sample, where the models were derived from without an independent validation sample. Results: The tumor diameter was larger and invasive and metastatic features were more common in the IDC-P than in the PAC group (P < 0.001). The distribution of extraprostatic extension (EPE) and pelvic lymphadenopathy was even greater, and the apparent diffusion coefficient (ADC) ratio was lower in the hpIDC-P than in the lpIDC-P group (P < 0.05). The ROC-AUCs of the stepwise models based solely on imaging features for distinguishing IDC-P from PAC and hpIDC-P from lpIDC-P and PAC were 0.797 (95% confidence interval, 0.750-0.843) and 0.777 (0.727-0.827), respectively. Conclusion: IDC-P was more likely to be larger, more invasive, and more metastatic, with obviously restricted diffusion. EPE, pelvic lymphadenopathy, and a lower ADC ratio were more likely to occur in hpIDC-P, and were also the most useful variables in both nomograms for predicting IDC-P and hpIDC-P.

• 전산구조공학
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• 제3권4호
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• pp.29-34
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• 1990

HP의 HP/Apollo시리즈 10000 TX(Visualization System)는 고성능 RISC그래픽을 사용한 최초의 워크스테이션으로서, 아폴로의 Multiprocessing PRISM 아키텍쳐와 강력한 3D 그래픽 엔진을 채택하고 있어, 시스템의 성능과 Image Quality, Openness 및 Flexibility를 높여줌으로써, 타 제품에 비해 탁월한 성능과 기능을 제공하고 있으며, 사용자의 투자에 대한 효과를 확실히 높여주고 있다.

• 대한전자공학회논문지
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• 제16권3호
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• pp.36-48
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• 1979

HP 2100 S computer의 disc operating system 을 사용한 본cross-assembler는 alpha-minicomputer 의 assembly language program을 source 입력으로 하여 이 alpha-computer 에 의한 실행 (execution)을 목적으로 16진수 code의 등가 object program 을 출력토록 설계되어 있다.

• 프린팅코리아
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• 제13권1호
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• pp.90-91
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• 2014

한국HP 인디고 총판인 (주)모나미이미징솔루션즈(대표이사 송하윤)는 구랍 3일 경기도 용인시 수지구에 위치한 모나미 본사 1층 데모센터에서 인쇄인 50여명이 참가한 가운데 오픈하우스를 개최했다. 오픈하우스에서는 MIS 소개, HP 인디고 디지털 프레스 성공사례 및 장비소개, 데모 및 샘플소개 등이 진행됐다.