• The Korean Journal of Nuclear Medicine Technology
• /
• v.17 no.2
• /
• pp.90-94
• /
• 2013

Purpose: In the PET/CT images, various artifacts cause degradation of the quantitative assessment. Most hotspot generated by radiopharmaceutical injection errors cause an artifact and degrade the quality of the images as well as the accuracy of the quantitative evaluation. The purpose of this study is to assess effectiveness of the elimination of the hotspot at the injection sites using shifting the center of DFOV (Display Field of View, DFOV) method and evaluate the quantitative evaluation of result. Materials and Methods: GE Discovery STE 16 (GE Healthcare, Milwaukee, USA) and 1994 NEMA phantom were used for imaging acquisition. Phantom was filled with 0.005 MBq/mL of $^{18}F-FDG$. A hotspot was artificially placed on the outside of the phantom. The ratio of hotspot area activity to background area activity was regulated as 200:1. After image acquisition with routine protocol, all of the images were reconstructed using the shifting the center of DFOV method that wasn't overlapped with hotspot. Those images obtained before and after applying the shifting reconstruction method were compared. ROIs (Region Of Interests) were set in the hotspot areas, meanSUVs and standard deviations were calculated. Percentage differences were calculated with those meanSUVs and standard deviations. The evaluation on the effects of the shifting reconstruction method was done by comparison of the meanSUVs and the standard deviations, which were calculated for background areas unaffected by hotspot. Results: In the areas of unaffected by hotspot, meanSUVs before and after applying the shifting of center of DFOV method were $0.67{\pm}0.06g/mL$ and $0.65{\pm}0.06g/mL$, respectively. In the artifact areas affected by hotspot, meanSUVs before and after applying the shifting of center of DFOV method were $0.32{\pm}0.08g/mL$ and $0.56{\pm}0.12g/mL$, respectively. The percentage differences of the area adjacent to the hotspot and the area distant from the hotspot were 65.3% and 97.4%, respectively. Conclusion: In the PET/CT images, meanSUV was improved by 32.1% when the effect of artifact was removed with application of the shifting the center of DFOV methode. In other areas unaffected by artifacts, meanSUVs were not significantly different after applying DFOV center shift method. As shown in the result, adverse effects of hotspot made by swelling in the injection site can be reduced by applying DFOV center shift method. Therefore, DFOV center shift method can be applied for the more precise quantitative evaluation, and contribute to the increase of the diagnostic value of the images.

• ETRI Journal
• /
• v.46 no.2
• /
• pp.333-346
• /
• 2024

Various techniques for noninvasively focus microwave energy on lesions have been proposed for thermotherapy. To focus the microwave energy on the lesion, a focusing parameter, which is referred to as the magnitude and phase of microwaves radiated from an external array antenna, is very important. Although the finite-difference time-domain (FDTD)-based time-reversal (TR) focusing algorithm is widely used, it has a long processing time if the focusing target position changes or if optimization is needed. We propose a technique to obtain multistatic data (MSD) based on Green's function and use it to derive the focusing parameters. Computer simulations were used to evaluate the electric fields inside the object using the FDTD method and Green's function as well as to compare the focusing parameters using FDTD- and MSD-based TR focusing algorithms. Regardless of the use of Green's function, the processing time of MSD-based TR focusing algorithms reduces to approximately 1/2 or 1/590 compared with the FDTD-based algorithm. In addition, we optimize the focusing parameters to eliminate hotspots, which are unnecessary focusing positions, by adding phase-reversed electric fields and confirm hotspot suppression through simulations.