• Korea Trade Review
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• v.43 no.2
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• pp.47-67
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• 2018

The purpose of this study is to determine factors of FDI inflows which positively influence economic development. While MNCs ultimately decide on which country to engage in FDI, it can be affected by the general investment environment of host countries. Thus, it may be closely linked to national macro socio-economic factors. In the fixed-effect panel regression analysis using 30 years of data of 13 developed countries and 15 developing countries, results indicate that labor redemption exerts the greatest influence on global FDI inflows; this implies that FDI decisions are based on locations featuring higher productivity by the reduction of labor costs. According to the level of economic development, the motive of FDI inflows differs. In developed countries, GDP, government expenditure and consumer expenditure exert the greatest influence on FDI inflows; which shows characteristics of market seeking and horizontal investment. However, in developing countries, labor redemption and human capital exert the greatest influence on FDI inflows; which shows characteristics of efficiency seeking and vertical investment.

• Information Systems Review
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• v.21 no.2
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• pp.69-89
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• 2019

Recently, consumers are increasingly interested in the sharing economy, which utilizes various resources by sharing unused or under-used products/services with others. This study focuses on Airbnb, a representative sharing economy platform, to identify the success factors of the sharing accommodation services. The key properties of sharing accommodation services are extensively surveyed from extant literature and are classified them into the three important factors (economic, convenience, and trust) that influence the success of room-sharing services. The research data include 1,673 Airbnb hosts who offered accommodations in New York City, USA, in June 2018. The research variables of economic-, convenience-, and trust-related factors are utilized in the empirical analyses. The results of this study show that the number of available facilities, flexibility of refunds, the response rate and time to customer requests, and the status of Super host are positively associated with guest satisfaction from sharing accommodation services. This study bears significant managerial implications by suggesting a set of practical guidelines to participants in sharing accommodation services.

• Journal of Microbiology and Biotechnology
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• v.18 no.4
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• pp.799-804
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• 2008

Retrovirus tropism can be restricted by host cell factors such as Fv1, TRIM5${\alpha}$, and LvI that inhibit infection by targeting the incoming viral capsid. The Fv1 gene inhibits murine leukemia virus infection in mice, but the precise mechanism of Fv1-mediated restriction is poorly understood. Our previous studies had demonstrated that Fv1-mediated viral tropism can be determined within the capsid protein at position 114. To study the interaction between Fv1 and CA, we introduced amino acid substitution and deletion at this site in the N-tropic AKV capsid gene. The mutated two-LTR proviral DNAs were introduced into SC-1 cells by transfection. After transfection, cell supernatants collected from transfected cells were tested for host range susceptibility. The result indicated that substitution of amino acids did not alter tropism, but the deletion of 114His produced a virus with unusual tropism. The novel phenotype produced here failed to replicate in Fv1-expressing cells. This mutant virus showing such an extreme restriction pattern would be useful for studying the mechanism of Fv1-mediated restriction.

• Tuberculosis and Respiratory Diseases
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• v.74 no.6
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• pp.269-273
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• 2013

Mucormycosis is a rare fungal disease that holds a fatal opportunistic fungal infection in diabetes mellitus, hematological malignancy, and immunocompromised host. Isolated pulmonary mucormycosis is extremely rare. Optimal therapy is a combined medical-surgical approach and a management of the patient's underlying disease. Herein, we report a case-study of isolated pulmonary mucormycosis which was being presented as multiple lung nodules in a patient with no underlying risk factors. Considering that the patient had poor pulmonary functions, we treated him with only antifungal agent rather than a combined medical-surgical approach. After treatment with antifungal agent for six months, the nodules of pulmonary mucormycosis were improved with the prominent reductions of size on the computed tomography.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.5
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• pp.1919-1924
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• 2015

Polymorphisms in the region of the interleukin IL-28 gene on chromosome 19 have been related with clearance of hepatitis C virus (HCV), a major human pathogen responsible for chronic hepatitis, cirrhosis and hepatocellular carcinoma. About 3% of the world's population is infected with HCV. The long-term response to therapy is influenced by many host and viral factors, and recent evidence has indicated that some host genetic polymorphisms related to IL-28 are the most powerful predictors of virological response in patients with HCV. This study assessed frequency of the IL-28 polymorphism (rs8099917) in 50 patients (39 men and 11 women) with chronic hepatitis C using ZNA probe real time PCR new method. All patients were tested for genotype of HCV and the HCV viral load. In parallel, the levels of SGOT, SGPT and ALK enzymes were assessed. Treatment using Peg-interferon alpha with ribavirin was conducted for patients and subsequently samples were collected to detect any change in viral load or liver enzyme rates. The overall frequency of the TT allele is 74%, TG allele 20% and GG allele 6% and the percent of patients who had T allele was 84%. Clear reduction in viral load and liver enzymes was reported in patients with the T allele. Especially for genotype 1 which is relatively resistant to treatment, these alleles may have a role in this decline. In conclusion, we showed that IL-28 polymorphism rs8099917 strongly predicts virological response in HCV infection and that real-time PCR with Zip nucleic acid probes is a sensitive, specific and rapid detection method for detection of SNPs which will be essential for monitoring patients undergoing antiviral therapy.

• Journal of the Korean Institute of Telematics and Electronics S
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• v.35S no.2
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• pp.58-69
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• 1998

A contrp; suste, fpr SCARA robot is designed for implememting a robust dynamic control algorithm. this study forcuses on the use of DSPs in the design of joint controllers and interfaces in between the host cotroller and four joint controllers and in between the joint controllers and four servo drives. The mechanical body of SCARA robot and the servo drives are selected from the commercially available ones. The four joint controllers, assigned to each joint one by one, are combined into a common system through a mother board hardwarewise and through the global memeory softwarewise. The mother board is designed to connect joint controllers onto the board through the slots adopting PC/104 bus structures. And, the global memory stores the common data which can be shared by joint controllers and the host computer directly, which virtually combines the whole system into one. To demonstrate the performance and efficienty of the sytem, a robust inverse dynamic algorithm is proposed and implemented for a faster and more precise control. The robust inverse dynamic algorithm is basically derived from an inverse dynamci algorithm and a PID compensator. Based upon the derived dynamic equitions of SCARA robot, the inverse dynamic algorithm is intitially implemented within 0.3 msec of the control cycle in this system. The algoithm is found to be not accurate enough for the high speed and precision tasks due to inherent modelling errors and time-varying factors. Therefore, a variable PID algorithm is combined with the inverse dynamic algorithm to support robustness of control performance. Experimental datfor the proposed algorithm are presented and compared with the result obtained from PID and inverse dynamic algorithm.

• International Commerce and Information Review
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• v.19 no.3
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• pp.63-82
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• 2017

This study explores the barrier factors of Chinese private-owned enterprises in overseas expansion in terms of corruption, political risk, market fluctuation, cultural difference, and firms resource endowments. To explore the existing practical backgrounds, it was investigated to private-owned enterprises dealing with foreign export companies where run business in Hohhot, Baotou and Ordos, Inner Mongolia, China. The result shows that the corruption and political risks of host countries do not have significant influence on business performance in 'Go global' strategy, while the market fluctuation of host countries has a negative effect on business performance. Cultural difference has a negative effect on business performance, and enterprises' resource endowments have a positive effect on business performance in 'Go global' strategy. Additionally, interviewees provide several substantial suggestions regarding the government policy and industry ecosystem to surmount the barriers of POEs' going global. Lastly, the authors discuss managerial implications and provide several suggestions for the future studies.

• IMMUNE NETWORK
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• v.9 no.5
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• pp.192-202
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• 2009

Background: Little information is available the role of Nitric Oxide (NO) in host defenses during human tuberculosis (TB) infection. We investigated the modulating factor(s) affecting NO synthase (iNOS) induction in human macrophages. Methods: Both iNOS mRNA and protein that regulate the growth of mycobacteria were determined using reverase transcriptase-polymerase chain reaction and western blot analysis. The upstream signaling pathways were further investigated using iNOS specific inhibitors. Results: Here we show that combined treatment with 1,25-dihydroxyvitamin D3 (1,25-D3) and Interferon (IFN)-${\gamma}$ synergistically enhanced NO synthesis and iNOS expression induced by Mycobacterium tuberculosis (MTB) or by its purified protein derivatives in human monocyte-derived macrophages. Both the nuclear factor-${\kappa}B$ and MEK1-ERK1/2 pathways were indispensable in the induction of iNOS expression, as shown in toll like receptor 2 stimulation. Further, the combined treatment with 1,25-D3 and IFN-${\gamma}$ was more potent than either agent alone in the inhibition of intracellular MTB growth. Notably, this enhanced effect was not explained by increased expression of cathelicidin, a known antimycobacterial effector of 1,25-D3. Conclusion: These data support a key role of NO in host defenses against TB and identify novel modulating factors for iNOS induction in human macrophages.

• Journal of Korea Multimedia Society
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• v.8 no.1
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• pp.71-78
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• 2005

When a PDA is used as a mobile terminal in an infrastructure network based on 802.11b standard wireless LAN, we measured and evaluated the performance of multimedia data transmission. In general, PDAs are mainly used tot receiving bulk data like multimedia data. However, while a PDA as a mobile host transfers multimedia data to a desktop PC as a fixed host in such a network, the time taken to receive data from the PC to the PDA is always longer than the time taken to send data from the PDA to the PC by at least 53%. Thus, we consider some critical factors that affect the time taken to receive Our experimental results show that with the PDA the time taken to access a file for writing is longer than the time taken to access a file for reading of to 4.11 times. In addition, a dramatic change of the site of the receiver window, from 686 bytes to 32,383 bytes, prolongs the time taken to receive. To transfer data without any inter-packet interval for the PDA and to increase the size of the TCP receive buffer will be effective in improving the delay to receive data.

• Asian-Australasian Journal of Animal Sciences
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• v.25 no.2
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• pp.278-285
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• 2012

Poultry products are an important source of Salmonella enterica. An effective way to reduce food poisoning due to Salmonella would be to breed chickens more resistant to infection. Unfortunately host responses to Salmonella are complex with many factors involved. To learn more about responses to Salmonella in young chickens of 2 wk old, a cDNA Microarray containing 13,319 probes was performed to compare gene expression profiles between two chicken groups under control and Salmonella infected conditions. Newly hatched chickens were orally infected with S. enterica serovar Enteritidis. Since the intestine is one of the important barriers the bacteria encounter after oral inoculation, intestine gene expression was investigated at 2 wk old. There were 588 differentially expressed genes detected, of which 276 were known genes, and of the total number 266 were up-regulated and 322 were down-regulated. Differences in gene expression between the two chicken groups were found in control as well as Salmonella infected conditions indicating a difference in the intestine development between the two chicken groups which might be linked to the difference in Salmonella susceptibility. The differential expressions of 4 genes were confirmed by quantitative real-time PCR and the results indicated that the expression changes of these genes were generally consistent with the results of GeneChips. The findings in this study have lead to the identification of novel genes and possible cellular pathways, which are host dependent.