• Korean Journal of Acupuncture
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• 제25권4호
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• pp.147-166
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• 2008

Objective : This study is achieved to know the way that we can use metabolomics for the scientific research of Korean medicine. Results : We elucidate that metabolomics can be contributed to four ways for objectification of Korean medicine 1. Diagnosis of BeunJungLonChi(辯證論治). 2. Application toward Personalized medicine. 3. Quantification of Herbal medicine. 4. Evaluation of efficacy/safety for Korean medicine formulation Conclusion : Metabolomics opens up a new opportunity to reinvestigate Korean medicine from holistic perspective. Furthermore, Metabolomics is expected to provide effective method in research of acupuncture and meridian.

• 대한한의학원전학회지
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• 제30권1호
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• pp.185-209
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• 2017

Objectives : The objective of this paper is to review the healing processes employed in the traditional age and discover the unique features found in the Korean Medicine through categorizing and analyzing the distribution of patients, and the aspects and results of treatments as recorded in Gyeongbosinpyeon, a historical text thought to have been authored by a regional doctor active in Joseon during the mid- to late-19th century. Methods : A table is created to view all of the total of 141 medical records introduced in the Gyeongbosinpyeon, and 7 categories were created to each contain 2 to 3 medical records that have special images. The paper provides their translation texts along with the original texts, and analyzed their medical and social significances by comparing each medical record. Results : The clinical competence displayed by the doctor who had worked in Joseon during the 19th century was surprisingly high, and it seems its values are worthy of dissemination when compared with Yeogsimanpil that has been introduced to the world. There is a great significance in how the principle of holistic treatments, the fundamental aspect of Joseon's medical study, was adhered. Additionally, the parts that show the historical text's author's medical activities and their unique characteristics are also worthy of attention. Conclusions : Korean medicine possesses a remarkable text called Donguibogam, but clinical behaviors' successes are not guaranteed solely with textual knowledge. It can be witnessed that such texts of authority and such medical records that have recorded actual activities complement each other in order to improve the quality of Joseon's study of medicine.

• 셀메드
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• 제13권14호
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• pp.16.1-16.14
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• 2023

Objective: Cerebral palsy (CP) is a neurodevelopment disorder attributed to an insult or injury to the developing brain with abnormalities in muscular tone, movement and motor skill. Improvement in quality of life and ameliorating symptoms can be achieved. Therefore, this case report details a distinctive approach to treating a 5-year-old male child with quadriplegic spastic cerebral palsy utilizing Unani treatment modalities. Methods: The treatment regimen commenced with 'Habb Ayarij for constipation followed by Sharbat Ustukhuddus administered orally. Notably, Sharbat Ustukhuddus was combined with Melia Azedarach L. leaves vapour bath. Subsequently, Roghan Babunna douche was performed followed by Dalk Layyin andcontinued until symptomatic improvement was observed. Majun Falasfa, Khamira Marwareed and Khameera Gauzaban were administered for 30 days. The therapeutic outcome included anthropometrical measurements, developmental milestones, spasm/reflex scale, and muscle power grading. Results and conclusion: Over the course of a 2-year follow-up, several clinical findings emerged. These included notable improvements in anthropometric measurements, developmental milestones such as improved head control and sitting ability, and a reduction in spasticity of the upper limbs, along with decreased muscle spasms. The therapeutic outcome of this individualized and holistic approach is potentially due to the multifaceted properties of medicinal plants (Musakkin wa Muharrik wa Muqawwi-i- A'sab wa Dimāgh, Munawwim, Dafi-i-Tashannuj, Muqawwi-i-Qalb-i-Ruh). Furthermore, the use of Dalk and Naṭūl was instrumental in providing nourishment to musculoskeletal cells and initiating intracellular signaling cascades. While these findings are encouraging, further research in the form of case series andrandomized controlled trials is warranted to validate the efficacy of this unique holistic approach.

• Journal of Oral Medicine and Pain
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• 제47권4호
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• pp.174-182
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• 2022

In chronic temporomandibular disorders (TMDs), constituent tissues such as muscles are sensitive to pain and psychological stress, which negatively affect the quality of life. In addition, since chronic TMDs is often accompanied by diseases such as psychological disorders and other chronic pain disorders, the diagnosis of those diseases and patient referrals are mandatory. The management of chronic pain in TMDs requires a multidisciplinary and holistic approach. Pharmacological therapy using cyclobenzaprine, serotonin and norepinephrine reuptake inhibitors, tricyclic antidepressants, progressive relaxation, and psychological approaches using cognitive behavioral therapy such as shifting negative thoughts about pain are all valid treatment options.

• 대한한의학회지
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• 제35권3호
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• pp.40-48
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• 2014

Objectives: This study aimed to review the characteristics of personalized medicine and Korean medicine, and the correlation between personalized medicine and Korean medicine. Methods: We investigated various studies in PubMed, Scopus and domestic Korean medicine journals. In addition, we discussed the topic based on literature. Results: Western medicine developed as evidence-based medicine. However, its limitations are being reached, so a new paradigm of medicine is needed. As a result, personalized medicine has appeared. Recently, through the development of human genomics, personalized medicine has been researched on the basis of individual genetic characteristics. Korean medicine has developed with a unique holistic approach and treats not the disease itself but the patient's body. Its characteristic is well expressed through syndrome differentiation and treatment. Syndrome differentiation represents the nature of person-centered medicine and becomes the root of personalized medicine. Conclusions: Compared with genome-based personalized medicine of Western medicine, Korean medicine could be classified as syndrome-based personalized medicine. It would be great to apply this characteristic to clinical practices.

• 대한한의학원전학회지
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• 제21권1호
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• pp.257-283
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• 2008

Western Medicine had been taking the occurrence of a disease as a physical matter and had tried to step forward from this angle till the late twentieth. But lately for about 20 years, a lot of researchers have started to understand the disease and human function as those in holistic system They supposed that the human function was the result of the interactions in 'Mind-Brain-Body' system and tried to explain and prove about the theory at the molecular level. The name of this new field of human science is 'Mind-Body Medicine' and in the center stand the 'Psychoneuroendoimmunology. Traditional Korean Medicine of which the core system was formed 2500 years ago, explains the complex interaction between mind and body with the theory of 'Mind-Brain-Body' system. To research on the correlation between mind and body, we tried to explain from the viewpoint of medical classic about the philosophical background, relations among mind, five viscera, and body, interaction between mind and body.

• 수면정신생리
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• 제30권1호
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• pp.13-21
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• 2023

The Seasonal Affective Disorder (SAD) is a disorder characterized by prolonged periods of depression and various physical and psychological symptoms experienced during specific seasons, typically winter. In this review aims to provide a comprehensive overview of SAD with a specific focus on psychophysiological aspects. Through the review from ancient times to the present, this paper explores the characteristics, causes, and underlying mechanisms of SAD. Particularly, it comprehensively reviews the research findings on the relationship between external factors such as light, sunlight, climate, and their association with SAD. Furthermore, the paper discusses the interplay between SAD and psychophysiological changes, along with the latest research trends in treatment and prevention strategies. By combining theoretical and practical perspectives on SAD, this article aims to provide a holistic understanding and offer suggestions for future research directions and clinical interventions.

• 동의생리병리학회지
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• 제30권6호
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• pp.370-375
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• 2016

Recent advances in systems biology are shedding a new light on the traditional medicine research. The systems biology highlights the way each component interacts with each other within a system, and the network behavior that emerges from such interactions. This feature of systems biology can accent the systemic aspects of Korean medicine such as the mechanism of action of herbal formulae, pattern differentiation, and the meridian systems, as both the Korean medicine and the systems biology theorize the human physiological functions and phenomena from a holistic point of view. This paper outlines the meaning of the recent Korean medicine research using the systems biology methodology. We discuss the methodologies of the two fields in a comparative manner, and overview the advantages and limitations of the integrated approaches. Finally, we suggest the future prospects for the systems biology inspired approaches to the Korean medicine research. The systems biology may provide a new modernized research methodology for the Korean medicine that can highlight its unique features.

• 한방비만학회지
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• 제20권2호
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• pp.131-137
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• 2020

Objectives: Korean Medicine Doctors (KMDs) have treated patients with obesity using a holistic approach with a multicomponent approach on counseling. However, there is currently no data regarding KMDs' counseling practices for weight loss. We conducted a retrospective chart review to better understand the Korean medicine counseling practice for weight loss. Methods: Twenty-one KMDs were involved in this project as practitioners. The contents of counseling were categorized based on patterns according to the counseling manual for the standardized management of obesity in Korean Medicine. Results: The counseling was conducted based on the theory of Korean medicine and the contents of counseling were different from patterns. However, the quality of the counseling were different from each KMD, and the counseling were focused on evaluating patient conditions and not on providing specific recommendations for lifestyle changes. Conclusions: Therefore, specific guidance of counseling for healthier lifestyle and dietary habits, and the training of the standardized manual training are needed.

• 사상체질의학회지
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• 제30권1호
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• pp.1-6
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• 2018

In modern western science, the humanities and social sciences are separated from the natural sciences. However, new interpretations should be explored based on holistic concepts and the principles of wholeness found in eastern nature. Examples of the latter from Korea include Lee Je Ma's Sasang Constitutional Medicine(SCM). We aimed to examine the features and problems associated with SCM, as well as approaches to these problems. Sasang constitutional medicine suggests that an individual's constitution is determined congenitally, and the body and mind need to be considered simultaneously when treating disease. And SCM thinks that individuality is important in clinical practice even in social relationship. SCM needs to develop for objective diagnoses, and basic research needs to be conducted in parallel such as study of the Confucian classics and neo-confucianism. Expanding the scope of patient-centric academic exchange has been raised as an important issue to exchange with Western medicine and so on. SCM can be the medicine that places humanity at the center, and its mentality could apply to preventive medicine and personalized medicine. So it has positive influence on construction of a healthy society and improvement of healthcare worldwide.