• Title/Summary/Keyword: heredity rule

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Clinical Study on the Distribution of Sasang Constitutions between Parents and their Offsprings (부모-자식간 사상체질 분포에 대한 임상 연구)

  • Lee Su Heon;Yoon Yoo Sik;Kim Hong Gie;Kim Jong Yeol
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.18 no.6
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    • pp.1904-1907
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    • 2004
  • The sasang constitutional medicine has been believed to be inherited. To ensure the heredity of sasang constitution and to look into the heredity pattern, we statistically analyzed constitutional relationship between parents and their children, using 173 clinical data couples registered to SCIB(Sasang Constitution Information Bank). The following results are obtained: The sasang constitution can be believed to be inherited, because the constitutions of children, whose parents have same constitutions, are mostly the same as their parents'. And it seems that one constitution is predominant to the other according to combinations of constitutions because constitution ratio of children are uniformly 2 to 1 in case the constitutions of parents are not same. Also it was confirmed that any sex of parents is not predominant by Chi-square test.

Effect of DanGuiBoHyulTangGami-Bang on the Alopecia and Hair Growth Stimulation (當歸補血湯加味方이 모발탈락 및 성장에 미치는 영향)

  • Kim, Phill-soo;Kim, Hee-taek;Roh, Seok-sun;Hwang, Chung-yeon
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.17 no.3
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    • pp.38-60
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    • 2004
  • We made an experiment if the extracts of DanGuiBoHyulTangGami-Bang(DBTG) and 15 kinds of the medical herbs used the materials of DBTG were effective on the hair formation palpation and the falling out of hair, and came to the following conclusions. 1. The extracts of Paeonia lactiflora, Cuscuta chinensis and Angelica tenuissima of DBTG consisted of the 15 kinds of the medical herbs kept the activity of 5${\alpha}$-reductase type Ⅱ from being active 75.3$\%$, 63.8$\%$. 75.5$\%$. 2. The hair growth index, 1.6(control group 0.8) of the extracts of DBTG bas a little effect on the hair growth palpation and that of Rubus coreanus 1.8(control group 0.4) was the most effective one of the medical herbs, and Paeonia lactiflora 2.3(control group 1.7) and Vitex rotundifolia 2.3(control group 1.5) showed the effect on hair formation palpation. 3. The hair growth period couldn't be extended by DBTG in this experimental stage. 4. The 15 kinds of constitution medicines of DBTG didn't have effects in dermal papilla cells DNA increase, IGF- I, KGF, HGF the revelation of a gene heredity, the protein synthesis of the hair follicle tissues. 5. All of the 15 kinds of constitution medicines of DBTG didn't have the antibacterial activity in Paper disc rule. 6. The results from the test of a radical scavenging activity of the 15 kinds of constitution medicines of DBTG showed that the extracts of Paeoria lactiflora, Scutellaria baicalensis, Rubus coreanus have the superior antioxidant activity in the concentration of 0.01$\%$ and 0.001$\%$ 7. In the formation controlled experiment, Vitex rotundifolia (70.6$\%$), Scutellaria baicalensis (47.1$\%$, Saposhnikovia (44.8$\%$) of the 15 kinds of constitution medicines of DBTG in the 50㎍/㎖ concentration controled NO forming and Vitex rotundifolia (12.7$\%$) controled NO forming in the 5㎍/㎖ concentration in order. 8. MTT(lC/50) of the extracts of Rehmannia glutinosa, Paeonia lactiflora, Scutellaria baicalensis, Lycium chinense, Rubus coreanus of the 15 kinds of constitution medicines of DBIG was more than 500㎍/㎖ and had the least cell virulence.

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