• Herbal Formula Science
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• v.25 no.1
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• pp.89-101
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• 2017

Objectives : This study was done to suggest appropriate number and time of dispensing herbal medicine for each Korean pharmacist. Methods : For this study, we visited one herbal dispensary institution which was considered as one of the biggest herbal dispensary preparing the largest number of prescription. We observed the work in the dispensary and recorded time for preparing prescriptions of 5 Korean Pharmacists. And we also recorded time for preparing prescriptions with toxic medicinal herbs of each Korean Pharmacist. Investigation has been done for 3 weeks, from 11, Jan. to 4, Feb. in 2016. Results : The whole dispensed prescription number of 5 Korean Pharmacists during 3 weeks were 899. These prescriptions include toxic medicinal herbs and general prescriptions. Ratio of prescriptions including toxic medicinal herbs was 38.4% while general prescriptions was 61.6%. Average direct dispensing time for herbal prescription of Korean pharmacists were 6.2 minutes. Applied personal allowances, appropriate number for dispensing in each day was 22.7. With allowances rate in general workplace, appropriate number for preparing was 20.5. According to ILO allowances regulation, appropriate number for preparing was 18.8. Conclusions : Suggested number of dispensing herbal medicine per day for each Korean pharmacist was 20.5. Applying this would be beneficial for development of Korean medicine circumstances.

• The Journal of Korean Medicine
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• v.36 no.1
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• pp.61-74
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• 2015

Objectives: The main purpose of this study is to find a solution for modernized classification of herbal medicinal preparations in dual medical systems. Through this study, we expect to provide a reasonable foundation of herbal medicine for public health. Methods: We studied legal or technical terms of herbal medicinal preparations from the past regulations, and through this procedure, we could suggest clear definitions of terms for herbal medicinal preparations. We also investigated documents for approval of herbal medicinal preparation from US, EU(European union), The People's Republic of China, Japan, so that we can refer to them to revise regulation for appropriate use of herbal preparations. Results: In Korea pharmaceutical affairs act, any basis of 'Crude drugs' does not exist. But in some subordinary notifications, the way that they use the 'Natural product medicine' is used as a means of limiting basic rights of doctor or pharmacist of Korean medicine compared to doctor or pharmacist. At the same time, in subordinary notifications, provisions are vague and not enough for scientific evidence of Korean medicine. Thus, we re-categorized herbal medicinal preparations into new drugs, drugs made from herbal medicinal preparations and suggested requirements for drug approval. Conclusions: Instead of using the term 'Crude drug preparations', and we should use term 'Herbal medicinal preparations' in related act and notification. And also we suggest to amend subordinary regulations and documents for approval of herbal medicinal preparations. Through this, we can make herbal medicinal preparations be more industrialized.

• Herbal Formula Science
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• v.24 no.1
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• pp.1-16
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• 2016

Objectives This study was conducted to investigate the management status of extramural herbal dispensary facility, which could serve as a foundation for further research and policy establishment.Method According to herbal dispensary data collected by Ministry of Health and Welfare, 78 sites were confirmed among 1,160 sites which checked extramural herbal dispensary facility. We carried out a survey on them. The survey consisted of 42 questions including general provisions, personnel management, spaces and facilities, equipment and utensils, procedure requirement for production and/or processing.Results From their responses, hygiene was regarded generally admittable. In personnel management, some answers that herbal medicines were prepared not by Korean medicine doctor or pharmacist, but by general worker. On preparation method, dosage frequency and volume were different among preparation facilities. Regarding facility management, prescription inspection was substantially carried out in many extramural preparation facilities, however, some of them was not.Conclusion There was a need for regulation of detailed management including facility, preparation, personnel management, etc., of extramural preparation facility. Furthermore, There was also a need for standardization of procedure on decoction, water management, medicinal herbs management, etc.

• Clinical and Experimental Pediatrics
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• v.52 no.5
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• pp.576-580
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• 2009

Purpose : Growth-promoting attempts are widespread in Korea, but little is known about their prevalence or associated factors. This study was designed to assess the prevalence of growth-promoting attempts among children visiting a university growth clinic. Methods : A questionnaire-based survey was carried out with 823 children (416 boys, 407 girls) who visited the growth clinic at Paik Hospital. Results : The mean age of the subjects was $10.4{\pm}2.6$ yr, and the height z-score was $-1.58{\pm}0.91$. Approximately 33.4% of the children had tried growth promotion. Among the height-gain methods, herbal medicine was the most frequently used (37.8%), followed by health-promoting supplements (37.1%), exercise or machine (3.0%), and growth hormone treatment (2.9 %). The mean age at which the parents began to worry about their children's height was 7.7 yr. The mean age at which they started height-gain methods was 8.9 yr for herbal medicine, 9.1 yr for health-promoting supplements, 9.4 yr for exercise or machine, and 9.9 yr for growth hormone treatment. Motivating factors included advice from relatives or friends (36.0%), advertisements in the Internet or newspaper (28.4%), advice from pharmacist (16.8%), and advice from their medical doctor (5.5%). The degree of satisfaction from the height-gain methods was 29.1% with growth hormone treatment, 6.6% with exercise or machine, 6.4% with herbal medicine, and 2.8% with growth-promoting supplements. Conclusion : Approximately one third of the children reported use of growth-promoting methods, but the satisfaction rate was not high. The benefits of growth-promoting methods should be carefully weighed against their costs and side effects.

• Journal of Chest Surgery
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• v.38 no.11 s.256
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• pp.746-760
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• 2005

Background: Following the implantation of heart valve prostheses, it is important to maintain therapeutic INR to reduce the risk of thromboembolism. The objectives of this study were to determine the causes of nontherapeutic INRs, and to identify the factors associated with nonadherences to warfarin therapy in Korean outpatients with prosthetic heart valves managed by a pharmacist-run anticoagulation service (ACS). Material and Method: A retrospective chart review was completed for all patients enrolled in the ACS at Seoul National University Hospital from March, 1997b to September, 2000. The data on 868 patients (5,304 visits) who were at least 6 months post-valve replacement were included. All possible causes of nontherapeutic INRs were documented for each patient visit. The association of covariates to noncompliance was investigated by univariate analysis. Result: The reasons for nontherapeutic INRs were identified as follows: inadequate dosage adjustment $(21\%)$, nonadherences to dosing regimen $(13\%)$, drug/herbal interactions $(12\%)$, changes in diet $(7\%)$, and indeterminate cause $(42\%)$. Younger age, shorter duration of ACS and longer duration of warfarin therapy were associated with nonadherence. Conclusion: In this study, nonadherence and interactions between diet and medications were found to be important factors influencing nontherapeutic INRs. Longer duration of enrollment in the ACS affected the adherence to warfarin therapy Positively whereas younger age and longer duration of warfarin therapy affected negatively.