• The Journal of Internal Korean Medicine
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• v.28 no.1
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• pp.115-123
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• 2007

Objectives : To investigate the correlations among alcohol consumption, alcoholic liver disorders, physical symptoms, and behaviors in heavy drinkers. Methods : 53 males who self-realized their severe alcohol consumption were enrolled in this study. 10 answers for a questionnaire, serum parameter, sonographic finding and body mass index were attained. The correlations between them were analyzed using Pearson's correlation and Student's t-test. Results : The average consumption of alcohol in these subjects was 2.5-fold over social drinkers. The incidence of alcoholic hepatitis was around 30%, while fatty liver 73%, and abnormal GGT 77%, respectively. No specific correlation between average volume of daily alcoholic consumption and alcohol-related hepatic parameters was shown in this study, but correlative tendency between fatty liver and body mass index was exhibited. Conclusions : This study may indicate that alcoholic liver injuries are caused by not just volume of alcohol consumed but more mixed factors including inherited genetic components, body fat mass, foods and other physical or emotional stress.

• The Korea Journal of Herbology
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• v.34 no.1
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• pp.67-74
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• 2019

Objectives : Alcohol hangover is a common phenomenon which basically occurs after heavy drinking. Moreover, heavy alcohol consumption leads to acute and chronic diseases. We investigated the effect of herbal mixture (SJ) on alcohol metabolism in serum or/and liver. Methods : 5W-old Sprague Dawley rats were used for the study. To overnight fasted rats, 0.9% saline or SJ extract was administrated per os before alcohol treatment. Then, 40% alcohol was orally administrated to all rats in 30 mins. Ethanol, acetaldehyde concentrations, alcohol dehydrogenase (ADH), acetaldehyde dehydrogenase (ALDH) activities were measured by assay kits. Aspartate aminotransferase (AST) and alanine transaminase (ALT) were measured by analyzer. Results : Ethanol and acetaldehyde concentrations lowered in SJ groups compared with CON group. Especially, acetaldehyde concentration significantly decreased in SJ groups compared with CON group. AST and ALT levels tended to increase in SJ groups compared with CON group but there was no significant difference between CON group and SJ groups. ADH activity in serum was higher in SJ groups than CON group but no significant difference in liver. ALDH activity in both serum and liver showed significantly increased in SJ groups compared with CON group. Conclusions : Treatment of SJ extract showed not only reducing concentration of alcohol and acetaldehyde but also increasing activities of ADH and ALDH. These results suggest SJ may influence in alcohol metabolism via control of metabolic enzyme activities and metabolite. Therefore, SJ, herbal mixture, might have a function of preventing hangover after drinking alcohol.

• Journal of the Korean Dietetic Association
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• v.7 no.3
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• pp.248-257
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• 2001

The purpose of this study was to investigate the effect of smoking on dietary behavior and nutrient intake among the male college students. The subjects were divided into three groups; non smoker(n=84), moderate smoker(n=68), and heavy smoker(n=89) according to duration and degree of smoking. And they were asked for general characteristics, life style, eating pattern, food frequency, and nutrient intake using questionnaire and 24-hr recall method. The mean age, height, weight, and BMI of the subjects were 26.2$\pm$6.2 years, 173.3$\pm$5.3㎝, 66.5$\pm$9.3㎏, and 22.1$\pm$2.7㎏/$m^2$, respectively. The type of residence and frequency of alcohol drinking were significantly different among three groups; the frequency of self-boarding and alcohol drinking in moderate smoker and heavy smoker was higher than those in non smoker. Comparing with non smoker, the frequency of skipping meals, especially breakfast and supper, was significantly high in moderate smoker and heavy smoker. The most common reason why heavy smoker skipped meals was ‘eating habit’, while it was ‘lack of time’ in non smoker. The results showed that the heavy smoker tended to drink coffee more often compared to the other two groups. There were no significant differences in nutrient intakes among three groups. In conclusion, heavy smoking students have unhealthy dietary behaviors in terms of high frequency of alcohol drinking, habit of skipping meals and frequent coffee drinking showing a strong need of proper education on smoking withdrawal and meal practice for them.

• Journal of Nutrition and Health
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• v.24 no.1
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• pp.58-65
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• 1991

The effect of habitual alcohol consumption on the nutrient intake. body weight and serum values were studied in 194 upper middle class men aged 35-55yr. living in Seoul. Each subject was interviewed to get information of alcohol and nutrients intake. Blood samples were taken. Mean values for each variable were compared by fertile of alcohol intake. The average alcohol consumption of the subject was 32.2g/day. Most of times foods were taken along with drinks. The subjects preferred food items such as meat. fish, nuts. dry fishes when they drink. High alcohol consumers had a significantly higher intake of calorie. protein, fat. Fe, and riboflavin compared to nondrinkers and moderate drinkers. Body weight was significantly higher in high alcohol drinkers followed by moderate and nondrinker groups. They also showed the higher serum values of triglyceride and r-GTP. High alcohol consumption resulted in an increased intakes of most nutrients especially calorie and fat which leads to higher body weight and higher serum concentrations of triglyceride and r-GTP. Therefore it seems that heavy alcohol drinkers are more prone to obesity and related chronic diseases.

• Korean Journal of Human Ecology
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• v.19 no.3
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• pp.577-588
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• 2010

This study was conducted to investigate the changes in alcohol consumption of male university students in Daegu, Korea and their drink-related behavior. The study focused on these changes over a decade using self-administered questionnaire surveys and health examinations that were carried out at a university campus in 1999 and in 2009. In both years more than 85% of students responded that they drank alcohol. However, significant increases in the frequency and amount of alcohol consumption were found (p<.001). The main influence on students' drinking behavior was friends/peers in both years. The most frequently preferred alcohol of respondents was so-ju (a traditional Korean liquor) in both years. However, the most frequently preferred type of food to accompany drinking had significantly changed (p<.01). Other changes including the increase of drinking speed and smoking during drinking were found to have significantly changed (p<.05) while significant difference regarding the decrease in food intake during drinking was not found. No significant difference in the amount of alcohol consumed was noted between underage drinkers and drinkers of above the legal drinking age. Heavy drinkers in the 2009 population had significantly higher systolic blood pressure than non-drinkers and moderate drinkers (p<.01). This study also indicates that there may be a rise in heavy drinking and/or binge drinking among drinkers including underage students. The results of this study suggest that alcohol-blood pressure associations are considered to be of concern even in young adults. This study also suggests the need for special alcohol prevention programs or campaigns to intervene in the behavior of students.

• Journal of Preventive Medicine and Public Health
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• v.37 no.2
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• pp.120-126
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• 2004

Objectives : This study sought to examine relationships between alcohol drinking and cardiovascular disease mortality and all-cause mortality. Methods : From March 1985 through December 1999, 2,696 males and 3,595 females aged 55 or over as of 1985 were followed up for their mortality until 31 December 1999. We calculated the mortality risk ratios by level of alcohol consumption. Among the drinker, the level of alcohol consumption was calculated by the frequency of alcohol comsumption and the type of alcohol. Cox proportional hazard model was used to adjust for confounding factors. Results : Among males, compared to abstainer, heavy drinker had significantly higher mortality in all cause(Risk ratio=1.35), cardiovascular disease(Risk ratio=1.52) and cerebrovascular disease(Risk ratio =1.66). Although not significant, moderate drinker had lower ischemic heart disease mortality(Risk ratio =0.38). Among females, there was no statistically significant association between alcohol comsumption and mortality. Conclusion : The results of this study suggest that alcohol drinking has harmful effect on all-cause mortality, cardiovascular disease mortality and cerebrovascular disease mortality among males, especially in heavy drinker among males. Minimal evidence on protective effect for cardiovascular disease mortality in low or moderate drinker is observed.

• Journal of Preventive Medicine and Public Health
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• v.45 no.5
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• pp.301-308
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• 2012

Objectives: To examine the association between alcohol consumption habit, types of beverages, alcohol consumption quantity, and overall and cancer-specific mortality among Korean adults. Methods: The alcohol consumption information of a total of 16 320 participants who were 20 years or older from the Korean Multicenter Cancer Cohort were analyzed to examine the association between alcohol consumption habit and mortality (median follow-up of 9.3 years). The Cox proportional hazard model was used to estimate the hazard ratio (HR) of alcohol consumption to mortality adjusting for age, sex, geographic areas, education, smoking status, and body mass index. Results: Alcohol drinkers showed an increased risk for total mortality compared with never drinkers (HR, 1.72; 95% confidence interval [CI], 1.38 to 2.14 for past drinkers; HR, 1.21; 95% CI, 1.06 to 1.39 for current drinkers), while past drinkers only were associated with higher risk for cancer deaths (HR, 1.84; 95% CI, 1.34 to 2.53). The quantity of alcohol consumed per week showed a J-shaped association with risk of mortality. Relative to light drinkers (0.01 to 90 g/wk), never drinkers and heavy drinkers (>504 g/wk) had an increased risk for all-cause and cancer deaths: (HR, 1.18; 95% CI, 0.96 to 1.45) and (HR, 1.39; 95% CI, 1.05 to 1.83) for all-cause mortality; and (HR, 1.55; 95% CI, 1.15 to 2.11) and (HR, 2.07; 95% CI, 1.39 to 3.09) for all cancer mortality, respectively. Heavy drinkers (>504 g/wk) showed an elevated risk for death from stomach and liver cancers. Conclusions: The present study supports the existence of a J-shaped association between alcohol consumption quantity and the risk of all-cause and cancer deaths. Heavy drinkers had an increased risk of death from cancer overall and liver and stomach cancer.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.9
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• pp.4965-4972
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• 2013

This study aimed to discuss the consumption of alcohol as a risk factor for major cancers. We performed a search in the PubMed database, using the following inclusion criteria: meta-analysis published in English in the last 10 years that addressed the relationship between alcohol and the risk of developing cancer. The results indicate that moderate to heavy consumption of alcohol increases the risk of developing cancer of the oral cavity and pharynx, esophagus, stomach, larynx, colorectum, central nervous system, pancreas, breast and prostate. This review did not find any association between alcohol consumption and an increased risk of cancers of the lung, bladder, endometrium and ovary. It was also observed that alcohol consumption may be inversely related to thyroid cancer. Our systematic review has confirmed consumption of alcohol as a risk factor for the development of several types of cancer.

• Korean Journal of Health Education and Promotion
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• v.14 no.2
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• pp.69-94
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• 1997

Recently, occurrence of alcohol-involved traffic accidents is increasing while all the accidents by violation of law except drunk driving. Traffic accidents by drunk driving has a great external cost. In detecting drunk driving, blood alcohol content Many studies reported close correlation between blood alcohol content and traffic accidents by drunk driving. The risk of traffic accidnet increases exponentially as blood alcohol content increases. To control traffic accidents by drunk driving, decide target population. Heavy drinkers are few and responsible for a small part of the loss while casual drinkers are many and responsible for a large part of the loss. Casual drinkers need to be included in the targer population for the control of traffic accident by drunk driving. Stragegies to reduce the quantity of alcohol consumed, change the pattern of drink, such as frequency of drinking, raise of perceived risk of accident need to be sought.

• Korean Journal of Adult Nursing
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• v.19 no.2
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• pp.295-304
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• 2007

Purpose: The purpose of this study were to investigate the level of family support, alcohol consumption and drinking motives in patients with liver cirrhosis and to examine the relationships among those variables. Methods: The subjects consisted of 60 patients with liver cirrhosis. Family support scale, Q-F methods and Drinking Motives Questionnaire were used to measure the level of family support, alcohol consumption and drinking motives. Results: The level of family support was 43.62. Prevalence of drinking was 90% and 43.3% were currently heavy drinkers. Alcohol consumption was related to sex and education. There were positive low relationships between the level of enhancement motive, coping motive, social motive, and Q-F Index. Conclusion: Alcohol drinking is a serious health problem in patients with liver cirrhosis. It is necessary to have an educational approach for controlling drinking and family support.