• 제목/요약/키워드: heat therapy

검색결과 384건 처리시간 0.032초

U937 세포에서 육계와 온열 병행 치료가 세포증식 억제와 세포사멸 유도에 미치는 연구 (Treatment of Cinnamomi Cortex combined with hyperthermia synergistically suppressed proliferation and induced apoptosis in U937 cell line.)

  • 안채령;박선향;김홍준;정민정;백승호
    • 대한한의학방제학회지
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    • 제27권1호
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    • pp.45-52
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    • 2019
  • Objectives : Hyperthermia is a widely used therapeutic tool for cancer therapy and a well-known inducer of apoptosis. Although the Cinnamomi cortex (CC) is a potent anticancer agent for several human carcinomas, it is less potent in the human U937 cell line. To explore any enhancing effects of CC with hyperthermia induced apoptosis, this study investigated the combined effects and apoptotic mechanisms of hyperthermia and CC in U937 cells. Methods : U937 cells were heat treated at $43^{\circ}C$ for 30 min with or without pre-treatment for 1h with CC and then incubated at $37^{\circ}C$ with 5% $CO_2$. Cell viability was analyzed by MTT assay and Trypan blue assay. Morphological changes reflecting apoptosis were visualized under microscope. Synergy effect of CC combined with hyperthermia were calculated by Compusyn software. The expression of proteins related to apoptosis and signaling pathways was determined by western blotting. Results : Hyperthermia with CC reduced cell viability and induced apoptosis. Combined hyperthermia and CC treatment markedly augmented apoptosis by upregulating proapoptotic proteins and suppressing antiapoptotic proteins, culminating in caspase-3 activation. Furthermore, the combined treatment, decreased the expression of in Bcl-2 family, cyclin D1, VEGF, MMP2 and MMP9 expression. Conclusion : This study provides compelling evidence that hyperthermia, in combination with CC, is a promising therapeutic strategy for enhancement of apoptosis and suggests a promising therapeutic approach for cancer.

베체트병으로 상초(上焦) 부위의 증상을 호소하는 환자에 대한 치험1례 (Traditional Korean Medicine for Treating Bechet's Disease Symptoms of the Upper Burner: A Case Report)

  • 민선우;문지성;김예슬;박지윤;홍정화;정지천
    • 대한한방내과학회지
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    • 제43권2호
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    • pp.130-143
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    • 2022
  • Objective: This case report presents the effects of traditional Korean medical treatment for a patient with symptoms of the upper burner due to Beçhet's disease. Methods: A 42-year-old male patient was treated with traditional Korean herbal medicine (herbal formulas and patent medicines), acupuncture, and cupping therapy. Neck, ocular, and right wrist pain and xerostomia were assessed daily with a numeric rating scale (NRS) and grading assessment tool for subjective symptoms. Results: For a total of 20 days over two hospitalizations, the patient's neck pain was relieved from NRS 4 to 1, the ocular pain from NRS 5 to 1, the right wrist pain from NRS 7 to 1, and the xerostomia from grade 8 to 1. Conclusion: These results show that Beçhet's disease symptoms of the upper burner can be relieved with traditional Korean medical treatment, although additional well-designed studies are required to confirm these findings.

Thermotherapy as an alternative to exercise for metabolic health in obese postmenopausal women: focus on circulating irisin level

  • Lee, Seung-Jea;Kim, Tae-Wook;Park, Tae-Hwan;Lee, In-Ho;Jang, Eun-Chul;Kwon, Soon-Chan;Lee, Hye-Jin;Choi, Jeong-Hwan;Lee, Jeong-Beom
    • The Korean Journal of Physiology and Pharmacology
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    • 제26권6호
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    • pp.501-509
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    • 2022
  • Irisin is a myokine caused by exercise that improves insulin resistance and weight loss. However, under unfavorable conditions such as air pollution, and during the pandemic, outdoor activities are uncomfortable. Therefore, in this study, the effect of heat therapy (half bath 42 ± 0.5℃ for 30 min) on irisin circulation levels as an exercise alternative for middle-aged obese women after menopause was investigated. Subjects were 33 women aged 49.54 ± 6.04 years, with parameters of height, 160.12 ± 4.33 cm, weight, 69.71 ± 7.52 kg, body surface area 1.73 ± 0.13 m2, body mass index, 27.19 ± 3.40 kg/m2. The results suggest that circulating irisin levels showed a significant increase after one-time thermotherapy (TH-1). However, the increase in circulating irisin levels after 15 treatments (TH-15, 5 days/week, 3 weeks) was significantly varied. The level of adiponectin, which increases fatty oxidation to reduce fatty deposition, increased significantly at TH-1, but further increased at TH-15, which was significantly different from the level of TH-1. In addition, the basic serum free fatty acid (FFA) level was significantly increased at TH-15 compared to TH-1. Significant differences were also found in the lipid profile (body mass index, waist circumference, and % body fat). Thermotherapy can significantly increase the tympanic temperature and induce changes in circulating irisin and adiponectin levels. Thus, it resulted in positive changes in FFA and lipid profiles. Therefore, repeated thermotherapy is effective in increasing circulating irisin levels in postmenopausal obese women.

한방의료기관의 온열 치료 기기 활용 현황 및 개발 수요에 대한 조사 연구 (A Survey on the Utilization and Demand of Thermotherapy Devices in Korean Medical Institutions)

  • 인소영;임수란;박지연;박정환;김송이
    • Korean Journal of Acupuncture
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    • 제40권4호
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    • pp.194-205
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    • 2023
  • Objectives : This study investigated the current utilization status of thermotherapy devices in Korean medicine (KM) institutions and identified areas for improvement and further development, as perceived by KM doctors (KMDs). Methods : An online survey was conducted, targeting KMDs primarily engaged in clinical patient care. The questionnaire included items about respondents' clinical practices, the extent of thermotherapy device usage, their opinions on these devices, and perceived improvement needs. The collected data underwent quantitative analysis. Results : From the 1,025 respondents, data from 862 respondents who provided complete responses were analyzed. On average, respondents utilized thermotherapy treatments for 80% of their patients. Infrared (IR) phototherapy unit, electrical moxibustion apparatus, and heater-based thermotherapy devices were predominantly owned by respondents, with IR being the most frequently used. The average satisfaction score for current thermotherapy devices was 79. A significant concern raised was the necessity for improved health insurance coverage and efficacy evaluation. Conclusions : This research has confirmed that the extensive use of thermotherapy devices by KMDs in treating primarily musculoskeletal and gastrointestinal ailments - common conditions among patients in KM institutions. The main areas identified for improvement encompass safety, cost-effectiveness, and device efficacy. Future enhancements in thermotherapy devices should address these crucial aspects.

황제내경(黃帝內經)에 보이는 한(汗)관련 서술(敍述)의 특징(特徵)에 대한 고찰(考察) (A Study on the Characteristics of Descriptions of the Perspiration in "Hwangjenaegyeong(黃帝內經)")

  • 유정아;장우창;백유상;정창현
    • 대한한의학원전학회지
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    • 제23권2호
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    • pp.205-223
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    • 2010
  • In Korean Traditional Medicine(abbreviated to K.T.M.), hyperhidrosis and anhidrosis are the targets of the medical treatment. Furthermore sweating appearance is also one of the important symptoms which explain a particular situation of the patient in K.T.M. And at "Sanghanron(傷寒論)" which is a traditional chief clinical bible written by Jang Gi(張機) later Han dynasty(漢代) in China made full use of the various kinds of diaphoresis[汗法] as a main medical treatment with purgation therapy[下法] and emetic therapy[吐法]. So the sweat in itself not only is the disease, but also is one of the symptoms explain a disease pattern. This thesis inquires into "Hwangjenaegyeong(黃帝內經)" referring to sweat which is the origin of recognition to the sweat in K.T.M. Some theses similar to this research had been made progresses and already reported, but most of them have classified the contents into biology, pathology, diagnosis, treatment after the model of western medical theory. In the aspect of comparative studying with other literature and clinic practical using, we found characteristics of referring to sweat in "Hwangjenaegyeong(黃帝內經)". And we classify the characteristics into some categories as follows. 1. There are some terms which make a title including sweat and symbolize the characteristics, for example sweat of soul[魄汗], sweat of death[絶汗], sweat of streaming[灌汗], sweat of weakness[白汗], sweat of sleep[寢汗], sweat of bright and heat[炅汗], sweat of kidney[腎汗], sweat of escaping[漉汗], cold sweat[寒汗], sweat on the head[頭汗], hyperhidrosis[多汗], heavy sweat[大汗]. But there aren't spontaneous sweat[自汗] or sweat like a thief[盜汗] which are the normal terms referring to sweat in history of K.T.M. And there are several descriptions about sweat appearance such as sweating in half of body[汗出偏沮], sweating in the rear end and thigh and knee[汗出尻陰股膝], hyperhidrosis in the neck and aversion to wind[頸多汗惡風], hyperhidrosis in the head and face and aversion to wind[頭面多汗惡風], cannot stopping the sweating under head[頭以下汗出不可止], make a person sweat to one's feet[令汗出至足], sweating like escaping[漯漯然汗出], sweating like soaking[汗出如浴], sweating become moist[汗出溱溱], hardly escaping sweat[汗大泄], escaping sweating[漉漉之汗], sweat moisten the pores [汗濡玄府], ceaseless sweating like pouring[汗注不休] sweating like pouring and vexation[汗注煩心], damp with sweat[汗汗然], sweating spontaneously[汗且自出], removal of fever with sweat drying[熱去汗稀]. That can be divided into sweat region and sweat form. 2. There are detailed explanations of the principle of perspirations caused by hot weather, hot food, hard working and meeting damp pathogen. 3. There are some explanations of the principle of removing fever due to the excessive heat from internal and external body through sweating by replenishing the body fluid. And many descriptions about overcoming the febrile disease by dropping temperature through sweating and many diaphoresis for curing. 4. There are some descriptions about five Jang organs perspirations and attachment of five mucous body fluid to five Jang organs. 5. There are pathogenic progresses after sweating affected by the Six Atmospheric Influences and water. And detailed explanations of disease mechanism a sweat leading to another disease. 6. There are descriptions about various sweat absent situations.

좌측 유방암 방사선치료에서 CPAP(Continuous Positive Airway Pressure)의 유용성 평가 (The efficacy of continuous positive airway pressure (CPAP) for patient with left breast cancer)

  • 정일훈;하진숙;장원석;전미진;김세준;정진욱;박별님;신동봉;이익재
    • 대한방사선치료학회지
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    • 제31권2호
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    • pp.43-49
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    • 2019
  • 목 적: 본 연구는 좌측 유방암 방사선치료에서 환자 호흡방법에 따른 영향에 대하여 치료계획을 통해 비교 분석하고, 깊은 들숨 호흡 정지법(deep inspiration breath hold, DIBH)에서 지속적 기도 양압(continuous positive airway, CPAP)의 유용성을 평가하고자 하였다. 대상 및 방법: 좌측 유방암 환자 총 10명을 대상으로 하였다. 모의치료에서 총 세 가지 호흡법을 적용하여 영상을 획득하였다: 자유호흡법(free breathing, FB); 깊은 들숨 호흡 정지법(DIBH); 들숨 호흡 정지법(inspiration breath hold, IBH); 여기서 DIBH에서는 자가호흡확인 기구인 abches(APEX, Japan)와 IBH에서는 CPAP가 적용되었다. 치료계획은 Ray Station(5.0.2.35, Sweden)을 이용하였고, 용적 강도변조 회전방사선치료법(volumetric modulated arc therapy, VMAT) one partial Arc을 환자당 동일 각도로 적용하였다. 치료계획용적(planning target volume, PTV)의 총 처방선량은 50Gy(2Gy/fx)로 설정하였다. 치료계획분석은 PTV의 95% dose(D95), 처방선량지수(conformity index, CI)와 선량균질지수(homogeneity index, HI)를 비교 분석하였다. 손상위험장기(Organ At Risk, OAR)인 폐, 심장, 왼내림 앞가지동맥(left anterior descending artery, LAD)을 분석하였다. 결 과: 동축의 폐(ipsilateral lung)의 평균용적 FB, DIBH(Abches), IBH(CPAP)에서 각각 1245.58±301.31㎤, 1790.09±362.43㎤, 1775.44±476.71㎤였다. PTV의 평균 D95는 각각 46.67±1.89Gy, 46.85±1.72Gy, 46.97±2.34Gy였다. 평균 CI(HI)는 각각 0.95±0.02(0.91±0.01), 0.96±0.02(0.90±0.01), 0.95±0.02(0.92±0.02)였다. 폐 전체의 V20(동측 폐)은 각각 10.74±4.50%(20.45±8.65%), 8.29±3.14%(17.18±7.04%), 9.12±3.29%(18.85±7.85%)였다. 심장의 평균 선량(Dmean)은 각각 7.82±1.27Gy, 6.10±1.27Gy, 5.67±1.56Gy였다. LAD의 최대선량(Dmax)은 각각 20.41±7.56Gy, 14.88±3.57Gy, 14.96±2.81Gy였다. LAD에서 흉벽(Chest wall)까지 평균거리는 각각 11.33±4.70mm, 22.40±6.01mm, 20.14±6.23mm였다. 결 론: DIBH와 CPAP에서 FB보다 폐 용적이 커짐으로써, 방사선치료영역인 흉벽과 심장의 거리가 멀어지는 효과 때문에 LAD의 선량을 감소시킬 수 있다. 좌측 유방암 방사선치료 시 DIBH방법의 대체방안으로 CPAP은 임상적 활용도가 높을 것으로 사료된다.

한방근무 간호사의 업무분석 (An Analysis on Nursing Activity in Oriental Hospital)

  • 강현숙;조결자;김광주;김귀분;조미영;서연옥;신혜숙;전은영;정숙자;이혜진
    • 대한간호
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    • 제33권5호
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    • pp.63-75
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    • 1995
  • The need of oriental nursing role is recently increasing. The implication of this trend is enormous not only for the need of independent of independent oriental nursing intervention. Hence, this study was designed to describe the characteristics of oriental nursing activity and identify the meaning of nursing activity in oriental hospital. A total of 24 nurses were selected by convenience sampling from eight units at one oriental hospital. A total of 168 data were collected using minute-by-minute recording during nurse s work shift. The data were analyzed using nova and scheffe method as post-hoc test The results of this study are as follows; 1. the category of nursing activity in oriental hospital 74.4% of nursing activity was the patient-oriented nursing care. The nursing activity included others (18.28%), the function-oriented nursing care (7.07%), and staff-oriented care (0.2%). 29.1 % of the patient-oriented nursing care was the direct care, and 24. 5 % of the patient-oriented nursing care was the indirect care. There was a lack of patient education and the communication patient. 2. Nursing activity in oriental hospital by characteristics 1) Nursing activity by unit For patient-oriented nursing care, there was a statistically significant difference among 8 units. In the critical care unit, the patient-oriented nursing care was mostly performed. For function-oriented nursing care, there was statistically significant difference among 8 units. In the physical therapy unit, the function-oriented nursing care was mostly performed. 2) Nursing activity in oriental hospital For all kinds of nursing activity, there was a statistically significant difference between shifts. In night shift patient-oriented nursing care, function-oriented nursing care, and other kinds of nursing care was mostly performed. Patient-oriented nursing care included indirect care, treatment set management, and the breaktime. In day shift, staff-oriented nursing care was performed. 3) Nursing activity in oriental hospital For all kinds of nursing activity, there was not a statistically significant difference by day. The day has not impact on nursing activity. 3. the meaning of activity in oriental hospital The results of this study show that the patient-oriented care was vital check, input! output check, medication, bedsore prevention, nasogastric feeding, oral care, catheterization care, perinatal care, nursing care associated with acupuncture and moxacautery, observation (fever, sweating), heat and cold application communication with patent and family, and patient room management In conclusion, two issues associated with the findings of the research appeated to be involved in the difficulty of nursing activity in hospital. The first issue was the nursing care in oriental hospital provided by nurses who have a limited understading of the principles of oriental medicine. The second issue was the deficiency of systematic guideling for oriental nursing activity. The findings suggest the need to develop the systematic guideline for oriental nursing activity. The need of continuing education for nurses who work in the oriental hospital, and the need of nursing education including oriental nursing are critical.

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여드름 치료를 위한 PWM 기반 광 조사 시스템 설계 (Design of PWM-Based Photo Irradiation System for Acne Treatment)

  • 김창수;임현수
    • 한국방사선학회논문지
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    • 제6권3호
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    • pp.207-215
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    • 2012
  • 광 역학치료(Photodynamic therapy: PDT) 중 하나인 기존의 LED 광 조사는 연속파(Continuous wave: C.W) 방식의 635 nm 파장으로 여드름 치유에 가장 많이 사용되어 왔으나, 이 방식은 에너지효율이 낮고 생체조직에 열이 많이 발생하여 개선의 방안이 필요했다. 본 논문에서는 에너지효율을 높이고 여드름 치료를 위하여 생체조직에서의 열적 파괴현상을 방지하기위해 PWM(펄스 폭 변조: Pulse Width Modulation)을 활용한 여드름 치료용 LED 광 조사장치를 설계하였다. 시스템 구성은 크게 Timer 모듈, PWM 모듈, 광학전달 장치로 크게 세구성하여 설계하였으며, 여드름 치료를 위한 피부 투과 깊이를 높이기 위하여 광학전달 장치는 660 nm 파장의 1 W LED를 사용하였다. PWM 제어를 이용하여 발생된 주파수와 파형을 확인하고, 660 nm LED의 출력에너지 및 생체조직의 표면온도를 확인하여 안정적인 에너지출력과 생체조직의 안정성에 대해 평가하였다. 그 결과 여드름 치료를 위한 660 nm 파장의 1 W LED 광 에너지를 얻기 위하여 C.W 방식으로 사용하였을 경우 전력손실이 높고 생체조직에서의 열적 파괴현상을 보였으나, PWM 방식을 구현함으로써 펄스 폭 변조를 통하여 LED의 전력소모를 낮추었고, 생체조직의 열적 파괴현상이 나타나지 않아 여드름 치료를 위해 사용할 경우 C.W 방식보다 PWM 방식이 더 안전하고 효과적일 것으로 사료된다.

단계(丹溪)의 학술사상(學術思想)이 한방부인과학(韓方婦人科學)에 미친 영향(影響)의 고찰(考察) (A Study of JuJinHyoung(朱震亨)'s Medical thoughts in Oriental Obstetric & Gynecology)

  • 윤종원;오규석;홍영욱;이태균
    • 동국한의학연구소논문집
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    • 제6권1호
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    • pp.205-229
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    • 1997
  • 금원사대가(金元四大家) 중의 한 사람인 주진형(朱震亨)은 주화론(主火論)의 영향을 받았지만 독창적인 "상화론(相火論)"과 "음부족이양유여(陰不足而陽有餘)"하다는 견해를 밝히면서 보음정이억상화(補陰精而抑相火)를 위주로한 치법(治法)을 제창하여 후대(後代)에 "자음파(滋陰派)"라고 불리운다. 이러한 단계(丹溪)의 의학사상(醫學思想)과 한방부인과학(韓方婦人科學)과 관련된 이론을 개괄하여 단계(丹溪)의 이론과 처방이 우리나라 한방(韓方) 부인과학(婦人科學)의 발전과정에 미친 영향을 고찰하였다. 그 결과 첫째, 단계(丹溪)의 증치사상(證治思想)의 특징은 거습담(祛濕痰), 조기(調氣), 자음청열(滋陰淸熱)의 치법(治法) 운용(運用)과 금욕적(禁慾的) 섭생(攝生)을 통한 양생론(養生論)이었으며, 둘째로 단계(丹溪)의 이론(理論)과 처방(處方)들은 <의방류취(醫方類聚)>와 <동의보감(東醫寶鑑)>에서 <단계심법(丹溪心法)>과 <단계심법부여(丹溪心法附餘)>의 내용을 대폭 수용함으로써 우리나라 한방부인과학(韓方婦人科學) 이론(理論)의 주요한 부분을 형성하는 계기가 되었으며, 셋째로, 부인과질환과 관련하여 월경병(月經病)에 조기(調氣) 및 거습담(祛濕痰)을, 불임증(不姙症)에는 월경불조(月經不調)와의 관련성(關聯性)은 물론 체형(體型) 체질별(體質別) 병기(病機)와 치법(治法)을 구분하였으며, "산전당청열양혈(産前當淸熱養血)" 이론에 의한 황금(黃芩) 백출(白朮)을 위주로 한 안태론(安胎論), "종담론치(從痰論治)"한 악조치법(惡阻治法), 난산예방(難産豫防), 산후(産後)의 "대보기혈(大補氣血)"등의 이론을 제시하여 단계(丹溪)의 학술사상이 우리나라 한방부인과학에 미친 영향은 많았던 것으로 사료된다.

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야제 (夜啼)의 한의학 치료에 대한 최신 중의학 임상 연구 동향 -2000년대 이후 발표된 임상 연구 논문을 중심으로- (Review of Clinical Research Literatures on Effect of Traditional Chinese Medicine for Pediatric Night Crying)

  • 김상민;이진용;이선행;도태윤
    • 대한한방소아과학회지
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    • 제32권3호
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    • pp.100-118
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    • 2018
  • Objectives The purpose of this study is to analyze some of the TCM (traditional Chinese medicine) clinical research literatures about pediatric night crying in order to learn clinical application of Korean medicine treatment for pediatric night crying. Methods We searched clinical trial literatures about TCM treatment of pediatric night crying from the CNKI (China National Knowledge Infrastructure) (January 2000 to June 2018). We analyzed the literature in regards to the treatment methods and the results. Results Among the 459 searched studies, 13 randomized controlled trials and 41 case studies were selected and analyzed. In most of the studies, the effectiveness of TCM in treating patients was significantly high, so we confirmed the effectiveness of TCM on pediatric night crying. The most commonly used pattern differentiations (辨證) were Spirit damage due to fright and fear (驚恐傷神), Spleen deficiency and cold (脾虛寒) and Heart fire heat (心火熱). Methods of treatment include herbal medicines (internal medicine and external application), massage therapy (Tuina methods), acupuncture and other treatments (bloodletting). The most commonly used herb medicines were Cicadidae Periostracum (蟬?), Poria Cocos (茯?), Glycyrrhizae Radix (甘草), Uncariae Ramulus et Uncus (釣鉤藤), Junci Medulla (燈心草), Fossilia Ossis Mastodi (龍骨), Atractylodis Rhizoma Alba (白朮), Cinnabaris (朱砂), and Coptidis Rhizoma (黃連). The most commonly used massage methods were Clearing Liver Channel (淸肝經), Clearing Heart Channel (淸心經), Kneading $Xi{\check{a}}oti{\bar{a}}nx{\bar{i}}n$ (?小天心), Supplementing Spleen Channel (補脾經), Clearing $Ti{\bar{a}}nh{\acute{e}}shu{\check{i}}$ (淸天河水), and Rubbing Abdomen (摩腹). Conclusions Based on the results of clinical studies from China, the use of Korean medicine for the treatment of pediatric night crying has been shown to be effective in relieving symptoms. Based on the results of this study, it is possible to widen the scope of Korean medicine by additionally reviewing clinical and experimental studies on pediatric night crying.