• 한국균학회소식:학술대회논문집
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• 한국균학회 2016년도 춘계학술대회 및 임시총회
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• pp.39-39
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• 2016

There is a growing consumer preference for self-medication, which has resulted in the growth of the Korean functional food market to \1.5 trillion in 2014. Functional foods that can modulate immune responses and enhance liver health are in the top 2 product-specific health functional food categories. The aim of this project was to develop and commercialize new health functional foods incorporated with Cordyceps militaris. Cordyceps genus includes about 400 species, many of which have been used as traditional medicines for many years in Asian countries. C. militaris belongs to the class Ascomycetes and has been used extensively as a crude drug and tonic food in East Asia. Owing to the various physiological activities of its main active constituent, cordyceptin, C. militaris is currently being used for multiple medicinal purposes. Recently, many studies have tried to elucidate the pharmacological mechanisms underlying the activities of Cordyceps spp., which include immune activation, anti-inflammatory, anticancer, and antiviral effects. After continuous attempts and research toward industrialization, C. militaris cultivated using brown rice was developed into a product by a standardized process and mass-cultivating system. It was successfully introduced into the market and was approved as a functional food ingredient for the first time in Korea. Based on this information, C. militaris containing functional food product for strengthening the immune system was released in August 2014 under the brand name "Dongchoong Ilgi." Dongchoong Ilgi is potentially beneficial for improving immune and liver functions and may enhance both the convenience and effectiveness of health functional foods taken by healthy people and patients with minor illness. In addition, the results of our study may be applicable for the development of health functional foods that could lower the risk of diseases such as the common cold and cancer.

• 한국임상약학회지
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• 제28권4호
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• pp.342-346
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• 2018

Background: Green tea extracts are approved as nonprescription drug and available as health functional foods, health foods, and beverages. Clinical information on the products is lacking. Methods: Information about the products on green tea nonprescription drugs was obtained from the website of the Korea Pharmaceutical Information Center. The Naver, i.e., a top ranking online search portal, was used for compiling the list of the health functional food products using key words of 'green tea catechin' on August 23, 2018. The recommended daily dosages of catechins were calculated as 30% of the total dried mass of green tea and about 50% of the catechins were considered as epigallocatechin gallate (EGCG). Results: A total of two types of nonprescription drugs containing green tea powder or extracts, nine health functional food products, and three types of health foods were found. The regulatory requirements of the EGCG exceeding 800 mg were reported to be associated with adverse effects of elevated liver enzyme. If consumers take several green tea products concurrently, such as nonprescription drugs with health functional foods or health foods, it could exceed the recommended amount of EGCG. Conclusion: The concurrent use of green tea products as nonprescription drugs, health functional foods, and healthy foods may lead to an increased exposure to EGCG. Pharmacists should be aware the availability of various types of green tea products and the potential risk of liver toxicity due to excessive consumption of EGCG.

• 한국식품영양과학회지
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• 제43권7호
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• pp.1112-1121
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• 2014

본 연구는 대도시 폐경기 중년 여성의 건강기능성식품에 대한 인지도 및 섭취 실태를 파악하여 향후 폐경기 전후 여성들을 위해 필요한 정보 제공 및 교육에 기초 자료를 제공하고자 실시되었으며 중요한 연구 결과는 다음과 같다. 폐경기 전후 중년 여성들은 자신의 건강 상태를 비교적 양호한 것으로 지각하고 있으며, 폐경 및 건강기능성식품에 대한 인식문항에서는 임신가능성 여부 및 폐경기 증상에 대해서는 높은 지식수준을 보였지만 폐경의 정의 및 건강 관련 사항에 대해서는 대부분 잘 모르는 것으로 나타났다. 또한 건강기능성식품에 대한 지식의 정답률은 48.7%로 지식수준이 높지 않은 것으로 나타났다. 그러나 건강기능성식품을 구매 또는 섭취한 경험이 있는 사람은 83.7%로 나타났고 구입처는 타인의 소개(35.0%)와 약국 병원(27.8%)이 가장 많았으며 건강기능성식품의 주요 섭취 이유는 질병 예방(29.6%), 영양소 보충(20.3%), 피로 회복(16.0%) 순으로 나타났다. 본 연구의 조사대상자인 폐경기 전후의 중년 여성들은 건강기능성식품을 구매할 때 효과를 가장 중요하게 생각하고 있으며, 일반 건강기능성식품의 경우 구매 또는 섭취한 경험이 있는 사람이 83.7%로 높게 나타났지만 폐경기 증상 완화를 위한 건강기능성식품의 경우 구입한 경험이 없는 대상자가 65.9%로 더 많았다. 또한 섭취한 건강기능성식품의 성분을 조금 알고 있는 대상자(56.4%)가 가장 많았고 모르는 대상자(25.5%)가 그 뒤를 이어 건강기능의 성분에 대한 지식이 매우 부족한 것으로 나타났다. 그러나 건강관심도에 따라서 건강기능식품의 구매빈도 및 섭취빈도, 폐경기 증상 완화를 위한 건강기능성식품 구매 및 섭취 여부에 유의한 차이를 보였다. 또한 폐경 증상 완화를 위해 콩 제품에 대한 인지도가 가장 높았으며 실제 섭취도 가장 많이 하는 것으로 나타났다. 폐경기 전후의 중년 여성들을 대상으로 실시한 본 연구 결과를 종합해 보면 이제는 사회에서 폐경을 맞는 여성들을 대상으로 교육을 실시하여 폐경에 대한 정확한 정보를 전달하고 폐경 후의 생활을 건강하게 보낼 수 있도록 정보제공 및 교육적 지원이 필요한 것으로 사료된다.

• 대한한방소아과학회지
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• 제23권3호
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• pp.143-153
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• 2009

Objectives The purpose of this study is to get the basic information from patients how much they understood about their medication and also to know whether patients are making reasonable drug choice between Health Functional Foods and Herbal medicine. Methods 500 questionnaires were handed out to the parents of students in two elementary schools located in OO, Junlabukdo province. 421 questionnaires were completed to be evaluated. Results Among 421 subjects, 53.0% were female, and 47.0% were male. The percentages of the subjects consuming Health Functional Foods and herbal medicine were67.7% and 67.8%, respectively. Among those people who consumed Health Functional Food, 44.1% were using nutritional supplements, red ginseng or ginseng products (26.9%), chlorella products (11.5%), and plum extract products (7.7%). As for the reason to consume Health Functional Foods were varied, but 'in order to be healthy, although currently displaying no illness.'(43.0%) were the most responses among the given choices. On the other hand, the reason for consuming herbal medicine was 'In order to grow taller'(26.1%), 'In order to cure weak physical state frequently displaying common illnesses',(25.9%), and 'In order to cure diseases.'(23.3%). For the questions about effectiveness after consumption,the 69.9% subjects said that it seemed to be effected, and that % was slightly higher than that of subjects with consuming Health Functional Foods(64.4%). For question concerning preferences between Health Functional Foods and herbal medicine, 57.5% chose herbal medicine, and this percentage was higher than that of Health Functional Foods(42.5%).As for the reasons of additional consumption of the Health Functional Foods, subject answered as 'Easy to consume.'(41,6%), which was the most common among the subjects consuming Health Functional Foods. On other hand, the subjects of herbal medicine answered as that herbal medicine is 'more effective'(45.7%), and 'more trustworthy in preventing side-effects.'(40.3%). After consumption of the herbal medication, only 3.9% of the subjects consuming either Health Functional Foods or herbal medicine had side-effects. The most common side-effects were 'dermal reaction' which is normally caused by Health Functional Foods and 'indigestion' problems caused by herbal consumption. Conclusions According to the 421 subjects those involved in study, the percentages of consuming Health Functional Foods(67.7%) and herbal medicine(67.8%) were similar. The most commonly consumed products were a type of Health Functional Foods which were the nutrition-supplying products. Ginseng or red ginseng products were the next commonly used products. Health Functional Foods were commonly consumed for preventing illness and maintaining health rather than any other purpose. In contrary, herbal medicines were more commonly consumed for purposes such as for growth or treating certain type of disease. As a result of consumption, more than half of both subject replied as 'satisfied'. As for the side effects, dermal reaction was the most common problem for those with consuming Health Functional Foods, while indigestion was the most common side effect from the subjects with consuming herbal medicine.

• 한국식품영양학회지
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• 제25권2호
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• pp.308-316
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• 2012

Proper skin care promotes good metabolism and the biological activity of skin, helps maintain the skin in a healthy and beautiful state when combined with nutritional nourishment. Health functional foods are being used for the purpose of enhancing efficient skin care. Health functional foods related to skin care maintain the epidermis, dermal fibroblast layer and subcutaneous tissue that form the skin. Efficient functional foods alleviate the signs of endogenous aging that come with getting older and exogenous aging caused by sunlight. Even though the field of skin care related to health functional foods has received less attention and been the subject of less research compared to functional cosmetics which are developing widely, this area of skin care that maintains and improves the layer of dermal fibroblast through the intake of food, is expected to progress with the commercialization of products in many fields when the related technical research development is galvanized and the related patents are applied for. Research into health functional foods related to skin care in Korea started rather late in comparison to other advanced countries where patents for relevant techniques have been applied for since 1990's together with research conducted on how they might be used for practical purposes. This study used the key words 'skin care, health functional food' to search for Korean patents that have been applied for at the Korean Intellectual Property Office from 1983 to 2011 using the KIPRIS database, in order to help researchers in the related fields by organizing the patented formulas for health functional foods for skin care which have gained attention recently. According to the number of registrations in each industry field, the total number of patents was 1,120 we screened the major patents among them, the field with the largest number was food foodstuff non-alcoholic beverage and preparation or treatment(A23L) with 135, then natural plant medicine & medical supplies and cosmetics(A61K) with 112, microorganisms or enzymes(C12N) with 63, heterocyclic compounds(C07D) with 44, horticulture or cultivation of sea weeds, forestry(A01G) 16 times, listed from the highest to the lowest number of applications. It has been revealed that food, foodstuff, non-alcoholic beverage and preparation or treatment(A23L) was the industry field where the most patents for health functional foods related to skin care were registered.

• 동아시아식생활학회지
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• 제15권1호
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• pp.11-19
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• 2005

This study was conducted to provide data on awareness and use of traditional foods, suggesting the desirable ways to succeed and develop traditional foods, and the possible direction of policies and applications for food industry. The study also aimed to figure out awareness of traditional food and dietary life behaviors of married women in order to offer or draw attention to new information for better healthy life styles. Five hundred and ten married women in parts of Seoul and Kyongki area were surveyed to figure out their awareness and use of traditional foods including some of fermented foods, such as Kimchi, Doenjang(soybean paste), and Gochujang(hot pepper paste). The results were summarized as follows. First the overall satisfaction degree with traditional foods reached as high as 74.4%. They preferred traditional foods because they are healthy(38.8%), seasonally celebrated(29.9%), and well known for a variety of fermented foods(28%). Second, Kimchi, Doenjang and Gochujang, home-made or factory manufactured in an old-fashioned way, were preferred. Third, the most frequently cooked traditional foods were Kimchi Chigae and Doenjang Chigae. The most preferred cooking methods using Gochujang were Jorim(stewing) and Bokkeum(roasting). These results showed that Kimchi, Doenjang, and Gochujang were still used in cooking by married women in parts of Seoul and kyongki area, which says those are still the traditional foods most of women think as important and essential. The producers of traditional foods have to consider the safety and improvement of taste and quality of ingredients in addition to the convenience in cooking, More researches should be conducted to enhance these aspects and to develop functional foods to satisfy various needs of consumers and to improve their health.

• 한국작물학회지
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• 제48권
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• pp.58-64
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• 2003

To enjoy a healthy life, it is important to have a well-balanced diet. However, in today's society, there is an increase in the consumption of preprocessed foods and frequency of eating out. Also the western diet, which is becoming move popular worldwide, contains relatively high levels of protein and fat, and a low amount of fiber, Furthermore, the increased availability of favorite foods has created a condition were the individual diet is less variable. With these conditions, it is difficult to maintain a diet that is nutritionally balanced. With these unbalanced diets, which are difficult to change, there has been an increase in adult disease and health problems, such as colon and breast cancer, It is speculated that metabolites for carcinogens are produced from diet components and that intestinal bacteria contribute to the production of these metabolites. Therefore, it is necessary to evaluate the relationships between health, diet, and intestinal microflora. Soybean oligosaccharide is composed of water-soluble saccharides that have been extracted from soybean whey, a by-product from the production of soy protein. This is mainly a mixture of mono-, di-, tri-, and tetrasac-charides, with the principle components being the oligosaccharide raffinose and stachyose. When consumed by humans, the oligosaccharides cannot be digested in the human duodenal and small intestinal mucosa, and these are selectively utilized by beneficial bifidobacteria in intestines. The results of acute and subacute toxicity tests, soy-bean oligosaccharides were nonpoisonous. Soybean oligosaccharides promote the growth of indigenous bifido-bacteria in the colon which by their antagonistic effects, suppress the activity of putrefactive bacteria. Also, they reduce toxic metabolites, detrimental enzymes and plasma lipid, and increase in the frequency of bowel evacuation and fecal quantities. Consequently, soybean oligosaccharides as functional foods components have potential roles in the prevention and medical treatment of chronic adult diseases. The study of processing property and physiological function of soybean oligosacchavides and development of high oligosaccharide variety allow the creation of new and exciting foodstuffs that aye functional healthy.

• Journal of Nutrition and Health
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• 제56권5호
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• pp.483-495
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• 2023

본 연구는 서울 및 경기지역에 거주하는 노인 250명을 대상으로 건강기능식품 섭취가 식생활에 미치는 영향을 파악하기 위해 수행되었다. 2주 이상 지속적으로 건강기능식품을 섭취하였을 때 건강기능식품 섭취군으로 판정하였고, 노인의 식생활 평가를 위해 구성타당도 평가가 수행된 노인 영양지수 (NQ-E 2021)를 활용하여 식사의 질을 평가한 결과는 다음과 같다. 본 연구대상자의 평균 연령은 70.8세이었고, 건강기능 섭취 여부에 따른 연령, 키, 체중 및 체질량지수에 유의적인 차이는 존재하지 않았다. 전체 조사대상자의 NQ-E 점수와 영역별 점수를 보면 NQ-E 52.5점, 균형 43.3점, 절제 56.7점, 실천 65.7점이었고, 영양지수 전체 17개 항목 중 60점 이하의 낮은 점수를 보인 항목은 총 7개였는데, '과일 섭취', '우유 및 유제품 섭취', '어패류 섭취', '달걀 섭취', '콩 및 콩 제품 섭취', '견과류 섭취'와 '단 간식 및 단 음료 섭취 절제' 점수가 낮아서 노인들이 전반적으로 다양한 식품군을 충분하게 섭취하지 못하는 것으로 평가되었다. 건강기능식품 섭취 여부에 따른 차이를 보면 전체 NQ 점수와 다양한 식품군을 섭취하는 균형점수에서 유의적인 차이를 보여 건강기능식품 섭취군에서 건강기능식품 비섭취군보다 유의적으로 높은 점수를 보였다. NQ 판정등급 비율에서도 건강기능식품 섭취군이 건강기능식품 비섭취군보다 NQ-E 점수와 균형 영역에서 [상] 등급이 8% 이상 유의적으로 더 많았다. 영양지수 문항별 점수에서 건강기능식품 섭취군은 과일, 어패류, 달걀, 견과류, 잡곡밥 섭취 및 건강한 식생활을 하려는 노력에서 건강기능식품 비섭취군보다 높은 점수를 보였다. 본 연구결과 노인에서 건강기능식품 섭취군이 비섭취군보다 영양지수 평가를 통해 전반적인 식사의 질이 높은 것으로 평가되었는데, 이는 건강기능식품 섭취군에서 균형과 실천 영역에 해당하는 문항의 점수가 높은 것에 기인하였다. 그러나 전반적으로 노인들의 영양지수 점수가 낮고, 특히 균형 영역에 해당하는 다양한 식품군의 섭취가 제대로 이루어지지 않으므로 노인 영양문제 개선을 위한 지속적인 노력이 강구되어야 할 것으로 사료된다.

• 동의생리병리학회지
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• 제20권2호
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• pp.449-454
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• 2006

This research was planned and executed to evaluate how the nutritional composition and antioxidants contents and antioxidative activity of Hongsambak. Also, can effect health conditions of people who are suffering from diet-related disease like obesity and hyperlipidemia by taking healthy foods with Hongsambak in a form of nutritional supplement with our daily meals. With this observation, we found out that Hongsambak has high content of dietary fiber and effect on antioxidative activity. We concluded that we could apply the components in a form of various foods. The information we received from this conclusion will be a basic information on how we can apply oriental medicinal resources into other foods and in the field of functional food research, which already draes sizable attention world-wide.

• Journal of Nutrition and Health
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• 제52권3호
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• pp.258-267
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• 2019

본 연구는 한국인 건강한 성인에게서 12주간 동충하초 주정추출물의 섭취가 면역기능 증진 및 상기도감염 예방효과에 대해 확인하였다. 면역관련 지표인 NK-cell activity는 시험식품 섭취군이 플라세보군에 비해 유의적으로 증가하여 (p = 0.047) 면역증강 효과에 대해 확인하였다. 또한, 점막 면역에 주요 역할을 하는 항체 IgA 변화량은 시험식품 섭취군에서 플라세보군에 비해 통계적으로 유의하게 증가하였다 (p = 0.035). 본 연구대상자의 상기도감염(URI) 발생률은 시험식품 섭취군과 플라세보군, 두 군 간 유의한 차이는 관찰할 수 없었다. 안전성 평가인 진단검사의학 검사와 활력진후 결과에서도 섭취군 내 및 섭취군 간 의미 있는 변화 또는 차이는 관찰되지 않았다. 본 연구에서 동충하초주정추출물의 섭취가 URI 발생률에 대한 유의한 변화는 관찰할 수는 없었으나 면역지표인 NK-cell 활성 증가와 혈청 IgA 농도 증가를 통해 선천성 면역과 후천성 면역을 증진시키는 작용이 있어, 잠재적인 상기도감염 예방 효과에 관련성 있을 것으로 사료되며, 항생제의 약물 의존도를 낮추며 삶의 질 개선 및 국민보건 향상에 기여할 것으로 사료된다.