• Journal of Animal Science and Technology
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• v.64 no.3
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• pp.531-538
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• 2022

In Italy, buffalo mozzarella is a largely sold and consumed dairy product. The fraudulent adulteration of buffalo milk with cheaper and more available milk of other species is very frequent. In the present study, Fourier transform infrared spectroscopy (FTIR), in combination with multivariate analysis by partial least square (PLS) regression, was applied to quantitatively detect the adulteration of buffalo milk with cow milk by using a fully automatic equipment dedicated to the routine analysis of the milk composition. To enhance the heterogeneity, cow and buffalo bulk milk was collected for a period of over three years from different dairy farms. A total of 119 samples were used for the analysis to generate 17 different concentrations of buffalo-cow milk mixtures. This procedure was used to enhance variability and to properly randomize the trials. The obtained calibration model showed an R² ≥ 0.99 (R² cal. = 0.99861; root mean square error of cross-validation [RMSEC] = 2.04; R² val. = 0.99803; root mean square error of prediction [RMSEP] = 2.84; root mean square error of cross-validation [RMSECV] = 2.44) suggesting that this method could be successfully applied in the routine analysis of buffalo milk composition, providing rapid screening for possible adulteration with cow's milk at no additional cost.

• Proceedings of the Korean Society of Life Science Conference
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• 2008.10a
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• pp.42.1-42.1
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• 2008

• Biomedical Science Letters
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• v.21 no.2
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• pp.77-83
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• 2015

Soy proteins have been extensively studied because of its multiple health benefits. However, the effects of soy proteins on human cervical cancer cells are still unclear. Therefore, this study investigated the effects of soy proteins on HeLa cells and human fibroblasts by using soybean peptides (SPs). SPs selectively increased the generation of reactive oxygen species and apoptosis in HeLa cells but not in fibroblasts. In addition, SPs suppressed the migration of HeLa cells. Although the molecular mechanisms underlying the effects of SPs on human cervical cancer cells need to be investigated further, our findings provide insights on the therapeutic effects of soy protein on cervical cancer.

• Food preservation and processing industry
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• v.8 no.2
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• pp.3-5
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• 2009

• Molecules and Cells
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• v.44 no.7
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• pp.433-443
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• 2021

Multi-omics approaches are novel frameworks that integrate multiple omics datasets generated from the same patients to better understand the molecular and clinical features of cancers. A wide range of emerging omics and multi-view clustering algorithms now provide unprecedented opportunities to further classify cancers into subtypes, improve the survival prediction and therapeutic outcome of these subtypes, and understand key pathophysiological processes through different molecular layers. In this review, we overview the concept and rationale of multi-omics approaches in cancer research. We also introduce recent advances in the development of multi-omics algorithms and integration methods for multiple-layered datasets from cancer patients. Finally, we summarize the latest findings from large-scale multi-omics studies of various cancers and their implications for patient subtyping and drug development.

• 대한예방의학회:학술대회논문집
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• 2001.10a
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• pp.450-451
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• 2001

• 대한예방의학회:학술대회논문집
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• 2001.10a
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• pp.333-334
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• 2001

• Journal of Korean Dental Hygiene Science
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• v.2 no.2
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• pp.41-51
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• 2019

Introduction: This study intended to identify the current oral health care status and demand of care workers for oral health education. Methods: A survey was distributed to care workers working in 11 nursing homes for older people located in the Chungcheongdo Province. Of those distributed, 217 questionnaires were collected and analyzed. To analyze the collected data, a frequency analysis, t-test, and one-way analysis of variance(ANOVA) were performed using SPSS version 18.0. Results: The demand for an educational course on the 'Management of Oral Health Care for the Aged People' had a score of 4.22 points(full marks were 5.0 points), whereas the score for the necessity for control of oral health was 4.29 points. The control of oral health for the aged people suffering dysphagia scored 4.27 points, whereas the control of oral health for older people who have dementia was 4.27 points. The score for a course on the nutritional control for aged people having difficulties in masticating foods was 4.27. Conclusion: It is clear that the development of educational courses and standardized manuals for care workers on aspects of oral health care is necessary. Therefore, it would be desirable to develop institutional infrastructure for dental hygienists to educate care workers on oral health.

• CELLMED
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• v.2 no.4
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• pp.34.1-34.5
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• 2012

The present study aimed to determine the hepatoprotective activity of the chloroform extract of D. linearis leaves (CEDL) using the paracetamol (PCM)- and carbon tetrachloride ($CCl_4$)-induced liver injury models in rats. The rats received $dH_2O$ (negative control), 200 mg/kg of silymarin (positive control) or CEDL (50, 250 and 500 mg/kg) orally once daily for 7 days and then were subjected to the hepatotoxic induction on the $7^{th}$ day. The samples (i.e. blood and liver) were collected and underwent biochemical and microscopical analysis, respectively. From the data obtained, both inducers caused significant (p < 0.05) increase in the levels of AST and ALT when compared to the control group, which were significantly (p < 0.05) reduced by CEDL in a generally dose-dependent manner. These biochemical findings were supported by the histopathological analysis and histological scoring. In conclusion, CEDL possesses potential hepatoprotective activity, which could be associated with its flavonoid and tannin contents with the mechanisms of hepatoprotection linked to either its antioxidant or anti-inflammtory/immunomodulating activities. Further in-depth studies are required to identify the responsible bioactive compound.

• The Korean Journal of Health Service Management
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• v.8 no.2
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• pp.221-232
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• 2014

This research aims to improve oral health knowledge through oral health education by investigating and analyzing the effect of subjective oral health knowledge and oral health behavior on personal oral hygiene management ability targeted for adults who visited a dental hygiene laboratory at B University in Busan for comprehensive dental hygiene management and procedure from September 23, 2013 to December 12, 2013, and provide basic data to improve adults' personal oral hygiene management ability by inducing behavior on oral health. Results derived from the research are as follows. Oral health education is a prerequisite to improve personal oral hygiene management ability through improvement in oral health knowledge and oral health behavior, which leads to improved personal oral health and furthermore promotion of national oral health through not just simply transmitting oral health knowledge, but desirable change in oral health behavior based on oral health knowledge.