• Genomics & Informatics
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• v.2 no.2
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• pp.92-98
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• 2004

A cDNA microarray experiment is one of the most useful high-throughput experiments in medical informatics for monitoring gene expression levels. Statistical analysis with a cDNA microarray medical data requires a normalization procedure to reduce the systematic errors that are impossible to control by the experimental conditions. Despite the variety of normalization methods, this. paper suggests a more general and synthetic normalization algorithm with a control gene set based on previous studies of normalization. Iterative normalization method was used to select and include a new control gene set among the whole genes iteratively at every step of the normalization calculation initiated with the housekeeping genes. The objective of this iterative normalization was to maintain the pattern of the original data and to keep the gene expression levels stable. Spatial plots, M&A (ratio and average values of the intensity) plots and box plots showed a convergence to zero of the mean across all genes graphically after applying our iterative normalization. The practicability of the algorithm was demonstrated by applying our method to the data for the human photo aging study.

• Journal of Preventive Medicine and Public Health
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• v.45 no.1
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• pp.8-13
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• 2012

Objectives: Recently injury has become a major world-wide health problem. But studies in Korea about injuries were very few. Thus, this study was conducted to analyze the trend of major injuries from 1991 to 2006 and to provide basic data for preventing injuries. Methods: This study was based on the National Statistical Office data from 1991 to 2006 and calculated to estimate the burden of major injuries by using the standard expected years of life lost (SEYLL) and total lost earnings equation. Results: For transport accidents, mortality, SEYLL and total lost earnings were increased from 1991 to 1996 and decreased from 2000 to 2006. On the other hand, for suicides, these were increased gradually. Since 2003, falls were included in ten leading causes of death. This study showed that injury causes major social and economical losses. Conclusions: We could reduce injury related premature death through active interest in injury prevention program.

• Journal of health informatics and statistics
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• v.43 no.4
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• pp.267-273
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• 2018

Objectives: An increase in the number of caregivers is necessary to provide services to the elderly, but more importantly, it is qualitative management for them. The purpose of this study was to identify occupational stress, job satisfaction, and organizational commitment and to explore the impact of occupational stress on job satisfaction and organizational commitment among caregivers employed in health service centers for the elderly. Methods: This descriptive survey was a cross-sectional correlational design of 118 caregivers. The questionnaire included occupational stress, job satisfaction, and organizational commitment. Stepwise multiple regression was applied. Results: Job satisfaction and organization commitment of caregivers were found to be above the average. There was a high level of job stress due to lack of job autonomy, job demands, and inadequate compensation. It has been found that the inappropriate compensation, organization system, work culture, and lack of job autonomy affected job satisfaction of caregivers. The factors affecting organizational commitment were inadequate compensation, job insecurity, and work culture. Conclusions: Efforts should be made to assess and complement the appropriateness of compensation and work culture that are taken to relieve job stress to enhance the job satisfaction and organizational commitment of caregivers.

• BMB Reports
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• v.45 no.5
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• pp.305-310
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• 2012

Allergic diseases such as asthma, allergic rhinitis, and atopic dermatitis are heterogeneous diseases characterized by multiple symptoms and phenotypes. Recent advancements in genetic study enabled us to identify disease associated genetic factors. Numerous genome-wide association studies (GWAS) have revealed multiple associated loci for allergic diseases. However, the majority of previous studies have been conducted in populations of European ancestry. Moreover, the associations of single nucleotide polymorphisms (SNPs) with allergic diseases have not been studied amongst the large-scale general Korean population. Herein, we performed the replication study to validate the previous variants, known to be associated with allergic diseases, in the Korean population. In this study, we categorized three allergic related phenotypes, one allergy and two asthma related phenotypes, based on self-reports of physician diagnosis and their symptoms from 8,842 samples. As a result, we found nominally significant associations of 6 SNPs with at least one allergic related phenotype in the Korean population.

• The Journal of the Society of Korean Medicine Diagnostics
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• v.12 no.2
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• pp.96-106
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• 2008

Background and purpose : Health is characterized by variability and a loss variability is associated with aging and disease. Normal healthy respiratory patterns are characterized by breath to breath variability. Cold-Heat score are quantified indices in Korean Medicine. The aim of this study is to analyze relations between 9 respiratory indices (including breath to breath variability) and cold-heat score by questionnaire. Method : Respiratory data were measured during 15 minutes and transferred to text file. We calculated 9 respiratory parameters in use of MATLAB7.1. After then we did correlation analysis of 9 respiratory indices and cold-heat score Results and conclusion : EIratio is showed significant correlation with Cold score and weighted Heat score.

• The Journal of the Society of Korean Medicine Diagnostics
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• v.12 no.1
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• pp.80-92
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• 2008

Background: The consequences of disordered breathing patterns are not only distressing to the patient but also expensive to our health care systems if they are not diagnosed and treated. So we performed this study to investigate clinical significants trough gigong, yoga and hyperventilation in oriental medicine and westen medicine Objective: To review the relationship of electrogastrography with autonomic nervous system and to study its clinical application. Method: We investigate the research results through internet search engine, Pubmed. Conclusion: Electrogastrography is a reliable, non-invasive method for recording gastric myoelectrical activity and is used for objectification of diagnosis related to gastric peristalsis. Gastric myoelectrical activity seem to involve autonomic nervous system, especially parasympathetic nervous system. The study should be continuing about relationship between electrogastrography and autonomic nervous system.

• Proceedings of the Korean Society of Computer Information Conference
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• 2019.01a
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• pp.9-10
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• 2019

항공기 소프트웨어는 기능적 실패 시 인명피해나 재산피해와 같은 큰 사고로 이어질 수 있다. 따라서 항공기 소프트웨어 개발과정에서 엄격한 검증 프로세스를 수행하지만 오류를 완벽히 제거하는 것은 어렵다. 병행 프로그램에서 발생하는 동시성 오류는 잘못된 동기화에 의하여 공유자원을 사용할 때 발생할 수 있다. 하지만 복잡한 인터리빙을 모두 고려하여 디버깅하기 어렵기 때문에 자율적으로 수리되어야 한다. 본 논문은 항공기 소프트웨어에서 함수 호출을 기반으로 동시성 오류를 자율적으로 수리하는 기법을 제시한다. 제시하는 기법은 모니터 및 컨트롤 엔진, 순차정보 제공 엔진, 건전성 관리시스템으로 구성된다.

• Journal of information and communication convergence engineering
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• v.20 no.1
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• pp.31-40
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• 2022

Coronary heart disease (CHD) is a comorbidity of COVID-19; therefore, routine early diagnosis is crucial. A large number of examination attributes in the context of diagnosing CHD is a distinct obstacle during the pandemic when the number of health service users is significant. The development of a precise machine learning model for diagnosis with a minimum number of examination attributes can allow examinations and healthcare actions to be undertaken quickly. This study proposes a CHD diagnosis model based on feature selection, data balancing, and ensemble-based classification methods. In the feature selection stage, a hybrid SVM-GA combined with fast correlation-based filter (FCBF) is used. The proposed system achieved an accuracy of 94.60% and area under the curve (AUC) of 97.5% when tested on the z-Alizadeh Sani dataset and used only 8 of 54 inspection attributes. In terms of performance, the proposed model can be placed in the very good category.

• International conference on construction engineering and project management
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• 2015.10a
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• pp.41-43
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• 2015

Urban Informatics, the application of data science methodologies to the urban development and planning domain, has been increasingly adopted to improve the management and efficiency of cities. This paper introduces state of the art use cases in major cities including New York, London, Seoul and Amsterdam. It also introduces recent advances in using Big Data by multi-lateral institutions for poverty reduction, and startups utilizing open data initiatives to create new value and insights. Preliminary research performed on using Seoul's open data such as building permit data and health code violations are also introduced to demonstrate opportunities in this relatively new but promising area of research.

• Journal of the Korean Institute of Oriental Medical Informatics
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• v.21 no.1
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• pp.1-13
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• 2015

The aim of this study was to investigate hospital employees' knowledge, recognition and practice on the protection of personal information. A total of 250 hospital employees were selected using convenient sampling in J province. The data were collected using self-reported questionnaire and were analyzed using SPSS 18.0 program and descriptive statistics, Chi-squire test, t-test, ANOVA, and Pearson correlation coefficients. Average score for knowledge, recognition and practice were significantly associated with gender, education, hospital size and there was a correlation among knowledge, recognition and practice. The results of this study will help to develop education program on the protection of personal information for hospital employees.