• Journal of Gastric Cancer
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• v.12 no.2
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• pp.88-98
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• 2012

Purpose: Local recurrence, due to residual tumor, may occur after endoscopic resection for early gastric cancer. The aims of this study are to evaluate the predictive factors for local recurrence, and suggest an appropriate follow-up biopsy strategy. Materials and Methods: We retrospectively reviewed 396 early gastric cancers from 372 consecutive patients, who underwent endoscopic resection between January 2002 and April 2008. Cumulative recurrence rates were determined by the Kaplan-Meier method, and Cox proportional hazard analysis was used to determine the risk factors for local recurrence. Results: Local recurrence at the endoscopic resection site was found in 17 cases, among the total 396 lesions, during a median follow-up period of 48 months. The 5-year cumulative local recurrence rate was 4.8%. Multivariate analyses determined that tumor involvement at the lateral resection margin [hazard ratio: 35.9; P<0.001], uncheckable lateral resection margin [hazard ratio: 16.8; P<0.001], uncheckable or involved deep resection margin [hazard ratio: 3.76; P=0.047], and piecemeal resection [hazard ratio: 3.95; P=0.007] were associated with local recurrence. If a lesion was positive for any of these risk factors, the 5-year cumulative recurrence rate was 27.0%, while local recurrence was not found in any lesion that lacked these risk factors. Most episodes of recurrence were found during the first or second follow-up endoscopic biopsy at the ulcer scar. Conclusions: Routine follow-up biopsies at the endoscopic resection site might be unnecessary in cases where an early gastric cancer lesion was endoscopically resected en bloc with tumor-free lateral and deep margins.

• Proceedings of the Technology Innovation Conference
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• 2002.06a
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• pp.203-223
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• 2002

In Korea, Public Research Institutes(PRIs) are today faced with the challenges of creating values by transferring technologies in store within themselves to private commercial sector. Recently, It has been increasingly pointed out that PRIs have the poor capability to valuate prospective technologies of their own, and don't run the reasonable technology transfer mechanism in terms of establishing royalty rate and initial payment, designing remuneration to inventor, screening qualified licensee, and controlling the moral hazard. This paper develops an enhanced mathematical model of technology transfer from a PRI to a private industrial firm with including the inventor as an important player. The model is made up of the main part which derives the optimal royalty rate by maximizing the social welfare and sharing risk fairly between players and some sub-parts. The one sub-part is a principal-agent model which makes it possible to control the moral hazard of inventors, and the other part provides the criteria for screening appropriate licensees. Moreover, the moral hazard between inventor and licensee is addressed by introducing the cost reduction function of efforts exerted by them. The model is able to relate the optimal royalty rate to the parameters that represent the environments under which the concerned parties operate. Especially, the ratio of initial payment over the value of transferred technology is calculated from the binding relation with the royalty rate. The paper shows that the model suggested here is more enhanced by comparing with the existing technology transfer mechanism. Finally, the paper allows us to find better strategies for effective technology transfer and further develop more sophisticated technology transfer model.

• 재활복지
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• v.17 no.4
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• pp.127-149
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• 2013

This study analyzed the hazard of unemployment and the influencing factors on the rate. Data came from the Panel Survey of Employment for the Disabled(PSED), 2010-2012, which is a longitudinal survey for 5,092 disabled people in Korea. For the main purpose of this study, the life-table method was used for describing the patterns of unemployment duration by disabled, and the cox proportional hazard model was used to identify significant factors on the unemployment duration. The results were as follows. First, according to the life table analysis, the unemployment rate to remain until the longest period of unemployment(25month) is 90.5%, and the rate of entry into the labor market was only 9.5%. Overall, the unemployment maintenance rate was high, the unemployment escape rate decreased after 12month. Second, looking at the results from the cox proportional hazards model, the unemployment escape possibility were increased for those who are male, are non-public benefit recipient with disability, have mild disability, and have less discrimination experiences. With these results, disability discrimination act which can reduce the disability discrimination in employment site should be strengthened. Also, the scheme of Nation Basic Protection Program should be modified to attract the employment of recipients with disability. Finally, policy targets having employment escape difficulty, such as women with disability, people with severe disabilities should be departmentalized. And employment service is provided in accord with the individual needs and characteristics.

• Proceedings of the KSR Conference
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• 2011.10a
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• pp.717-723
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• 2011

When the Balise(the device to transmit information between the on-board equipment and the wayside equipment) failure occurs, it may not be able to transmit data(Telegram) required for the train running. And in some cases, it may be able to cause an accident. Therefore, both the Balise failure affecting train safety running and the hazard in accordance with Balise failure require some activities to establish them. General failure mode & hazard analysis associated with the Balise are described in UNISIG SUBSET-036 spec & UNISIG SUBSET-088 spec. And, with reference to these specifications, safety activities are being performed. In recent domestic railway, the train control system applying ETCS(European Train Control System) Level 1, 2 is being serviced and is being planned, and as part of this system, the Balise is being applied. The design-method of the Balise device for each manufacturer are different, therefore the Balise failure mode & failure rate are different, either. But the functionalities & transmission-data format(Telegram) of the Balise in ETCS Level 1, 2 application for each manufacturer are identical. Accordingly, the hazard caused by function-fail can be identical, either. In order to establish these hazard, in this paper, we analyzed the detailed functions of the Balise. And we analyzed the Balise failure types & failure effects in accordance with the detailed functions.

• The Korean Journal of Emergency Medical Services
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• v.20 no.1
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• pp.71-82
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• 2016

Purpose: This research aimed to provide baseline data for undergraduate safety education by evaluating paramedic student risk perception and safety practice behavior regarding transport and disaster-related accidents. Methods: A total of 367 paramedic students at three different universities were surveyed using questionnaires. Risk perception questions about hazard, feeling of dread, and uncontrollable factors regarding seven items in transport and disasters were asked on a 7-point scale. Safety practice behavior consisted of 14 transport-related questions and 12 disaster-related questions in 4-point scale. All data were analyzed using SPSS Window 21.0. Results: Of 367 surveyed, 54.8% (201) were females, and 28.9% (106) were freshmen. In risk perception, 'drunk driving' in transport was the highest on average obtaining 6.49 points for hazard and 5.12 points for the feeling of dread. In disasters, 'war' recorded the highest average with 6.61 points for hazard and 5.71 points for the feeling of dread. In safety practice behavior regarding transport and disasters, a higher awareness of the need for safety education correlated with a significantly higher the rate of safety practice behavior (p <.001 respectively). Conclusion: The results indicate that undergraduates have inadequate perception of risk in emergencies. Safety education programs are needed to raise awareness of risks and to increase the safety practice rate.

• Korean Chemical Engineering Research
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• v.48 no.5
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• pp.603-608
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• 2010

A study has been conducted experimentally to investigate behavior of ignition and flame spread over metal dust deposits with particle size using by a developed apparatus and thermogravimetric analysis(TGA). Zr, Ta and Mg-Al(90:10 wt%) alloy metal powders including Mg and Ti with different particle size were used. Also we used PMMA(Polymethylmethacrylate) powder to compare the combustion properties to those of metal powders. When dust layers were more than 5 mm in thickness, the dependency of deposit depth on flame spread rate over dust layer was not shown. With decreasing mean particle diameter, flame spread rate over Ti dust layer decreased, while the spread rate over Mg dust layer increased. For mean diameter of $51{\mu}m$, fire spread rate over pure Mg dust layer decreased to about 50 percent in Mg-Al(90:10 wt%) dust layer. The oxide thickness of metal dust used in this study tended to be inversely proportional with the spread rate, and it was quite small for influence with particle size. From the results of TGA for Ti and Mg, weight increasing curves(550 for Mg, 578 for Ta) were observed in the oxidation process, and they seems to be caused by ignition of upper dust layer.

• Journal of the military operations research society of Korea
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• v.35 no.2
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• pp.33-49
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• 2009

The objective of this study is as follows. First, the hazard function on the failure probability density function of the K-1 tracked vehicles can be occurred in the form of the bathtub curve. Second, the failure mode may be different under two different operational situations. The research result shows that the bathtub curve can be fitted in the Weibull distribution, that assumes different shapes according to the specific stage of the system's life cycle. The K-1 tracked vehicle has a relatively high hazard(failure) rate at the time of its first service. The failure rate starts decreasing for a time immediately after it goes into service. After the break-in period, the surviving components have a fairly constant hazard rate. As the K-1 system ages, deterioration of its various parts takes place and the hazard rate starts Increasing. Second, the result shows the failure rate in the harsh operational environment is higher than that in the mild operational environment. In conclusion, the bathtub curve can be logically appropriate in establishing the depot overhaul cycle. Moreover, it is necessary for determining the right time of the depot overhaul to consider not only the age of defense equipment but also the different operational environment.

• 대한예방의학회:학술대회논문집
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• 1994.02a
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• pp.651-657
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• 1994

To assess quantitatively the association between benzene exposure and leukemia, we examined the mortality rate of a cohort with occupational exposure to benzene. Cumulative exposure for each cohort member was estimated from historical air-sampling data and, when no sampling data existed, from interpolation on the basis of existing data. The overall standardized mortality ratio (a measure of relative risk multiplied by 100) for leukemia was 337 (95 percent confidence interval, 154 to 641), and that for multiple myeloma was 409 (95 percent confidence interval, 110 to 1047). With stratification according to levels of cumulative exposure, the standardized mortality ratios for leukemia increased from 109 to 322, 1186, and 6637 with increases in cumulative benzene exposure from less than 40 parts per million-years (ppm-years), to 40 to 199, 200 to 399, and 400 or more. respectively. A cumulative benzene exposure of 400 ppm years is equivalent to a mean annual exposure of 10 ppm over a 40-year working lifetime; 10 ppm is the currently enforceable standard in the United States for occupational exposure to benzene. To examine the shape of the exposure-response relation, we performed a conditional logistic-regression analysis, in which 10 controls were matched to each cohort member with leukemia. From this model, it can be calculated that protection from benzene induced leukemia would increase exponentially with any reduction in the permissible exposure limit.

• Journal of Environmental Health Sciences
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• v.38 no.1
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• pp.66-72
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• 2012

Objectives: The AHERA method by the US EPA, ASTM E2356-04, and HSG264 by the UK HSE, all of which are hazard/risk assessment methods for asbestos-containing building materials, were reviewed and compared based on 231 homogeneous areas. In addition, the current Act on Asbestos Safety Management (enforcement: April 29, 2012) was reviewed and analyzed. This trial provided fundamental data for improving the current asbestos hazard/risk assessment method. Methods: For the hazard/risk assessment of 77 asbestos-containing public buildings including schools, 231 homogeneous areas were selected, each of which was assessed using AHERA, ASTM E2356-04, and HSG264. Results: The matching rate of the hazard/risk assessment stood at 20.4 percent between AHERA and ASTM, at 71.4 percent between AHERA and HSG264 and at 17.8 percent between ASTM and HSG264. The AHERA method includes a seven-category rating scale. There were three categories, two of which have three subcategories. ASTM provides two decision-making charts consisting of ten rating scales for current condition estimation and for potential for disturbance estimation. In addition, the HSG264 method has a total of 20 scores with four items, and then provides four grades. This HSG264 method cannot clearly separate current condition and potential for disturbance. Conclusions: In the Korean Act on Asbestos Safety Management, the hazard/risk assessment method for asbestos-containing building materials should consider balance between current condition estimation and the potential for disturbance estimation.

• Journal of the Korean Data and Information Science Society
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• v.27 no.5
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• pp.1253-1262
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• 2016

When there exists a change-point in hazard function, it should be estimated for exact parameter or hazard estimation. In this research, we compare the hazard change-point estimators. Matthews and Farewell (1982) parametric change-point estimator is based on the likelihood and Zhang et al. (2014) nonparametric estimator is based on the Nelson-Aalen cumulative hazard estimator. Simulation study is done for the data from exponential distribution with one hazard change-point. The simulated data generated without censoring and the data with right censoring are considered. As real data applications, the change-point estimates are computed for leukemia data and primary biliary cirrhosis data.