• Environmental Analysis Health and Toxicology
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• v.31
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• pp.11.1-11.6
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• 2016

Objectives A hazard assessment of di(2-ethylhexyl) phthalate (DEHP), a commonly used workplace chemical, was conducted in order to protect the occupational health of workers. A literature review, consisting of both domestic and international references, examined the chemical management system, working environment, level of exposure, and possible associated risks. This information may be utilized in the future to determine appropriate exposure levels in working environments. Methods Hazard assessment was performed using chemical hazard information obtained from international agencies, such as Organization for Economic Cooperation and Development-generated Screening Information Data Set and International Program on Chemical Safety. Information was obtained from surveys conducted by the Minister of Employment and Labor ("Survey on the work environment") and by the Ministry of Environment ("Survey on the circulation amount of chemicals"). Risk was determined according to exposure in workplaces and chemical hazard. Results In 229 workplaces over the country, 831 tons of DEHP have been used as plasticizers, insecticides, and ink solvent. Calculated 50% lethal dose values ranged from 14.2 to 50 g/kg, as determined via acute toxicity testing in rodents. Chronic carcinogenicity tests revealed cases of lung and liver degeneration, shrinkage of the testes, and liver cancer. The no-observed-adverse-effect level and the lowest-observed-adverse-effect level were determined to be 28.9 g/kg and 146.6 g/kg, respectively. The working environment assessment revealed the maximum exposure level to be $0.990mg/m^3$, as compared to the threshold exposure level of $5mg/m^3$. The relative risk of chronic toxicity and reproductive toxicity were 0.264 and 0.330, respectively, while the risk of carcinogenicity was 1.3, which is higher than the accepted safety value of one. Conclusions DEHP was identified as a carcinogen, and may be dangerous even at concentrations lower than the occupational exposure limit. Therefore, we suggest management of working environments, with exposure levels below $5mg/m^3$ and all workers utilizing local exhaust ventilation and respiratory protection when handling DEHP.

• Journal of Environmental Health Sciences
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• v.48 no.5
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• pp.272-281
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• 2022

Background: The constant consumption of chemical products owing to expanding industrialization has led to an increase in public interest in chemical substances. As the production and disposal processes for these chemical products cause environmental problems, regional information on the hazard level of chemical substances is required considering their effects on humans and in order to ensure environmental safety. Objectives: This study aimed to identify hazard contribution and spatiotemporal characteristics by region and chemical by calculating a hazard-based result score using pollutant release and transfer register (PRTR) data. Methods: This study calculated the chemical discharge and hazard-based result score from the Risk-Screening Environmental Indicators (RSEI) model, analyzed their spatiotemporal patterns, and identified hotspot areas where chemical discharges and high hazard-based scores were concentrated. The amount of chemical discharge and hazard-based risk scores for 250 cities and counties across South Korea were calculated using PRTR data from 2011 to 2018. Results: The chemical discharge (high densities in Incheon, Daegu, and Busan) and hazard-based result scores (high densities in Incheon, Chungcheongnam-do, and some areas of Gyeongsangnam-do Province) showed varying spatial patterns. The chemical discharge (A, B) and hazard-based result score (C, D) hotspots were identified. Additionally, identification of the hazard-based result scores revealed differences in the type of chemicals contributing to the discharge. Ethylbenzene accounted for ≥80% of the discharged chemicals in the discharge hotspots, while chromium accounted for >90% of the discharged chemicals in the hazard-based result score hotspots. Conclusions: The RSEI hazard-based result score is a quantitative indicator that considers the degree of impact on human health as a toxicity-weighted value. It can be used for the management of industries discharging chemical substances as well as local environmental health management.

• Proceedings of the KSR Conference
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• 2007.05a
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• pp.936-940
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• 2007

This paper is about the study on the verification method for railway system SIL which is frequency of hazard, composing Risk, one of the measurement standards for railway system safety. Frequency of hazard can be identified by using FMECA, or HAZOP, and the assessment of identified dangerous failure rate should be done by systematic methods such as FTA. Therefore, this paper provides the hazard identification level for SIL verification and the requirements necessary to verify the integrity of analysis activity.

• Proceedings of the KIEE Conference
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• 2015.07a
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• pp.545-546
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• 2015

Arc flash hazard study is required for the electric power system of industrial plant nowadays. Arc flash incident energy and level are calculated by arc flash hazard study. The arcing fault clearing time is determined by the response time of protection devices. This paper is protection devices coordination study to reduce potential incident energy for industrial electric power system.

• Proceedings of the KSR Conference
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• 2004.10a
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• pp.258-262
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• 2004

In this paper, the hazard factors on voltage rising effect between the rail and the earth were reviewed in subway system of AC traction line according to moving condition and location of the train. Site measuring of voltage rising between conductor part of train and station floor was performed to ascertain the risk level on the passenger. Plans for preventing hazard of rail-voltage rising and electrical shock on the passengers at platform were proposed.

• Journal of Gastric Cancer
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• v.12 no.4
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• pp.210-216
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• 2012

Purpose: To assess independent prognostic factors for lymph node-negative metastatic gastric cancer patients following curative resection is valuable for more effective follow-up strategies. Materials and Methods: Among 1,874 gastric cancer patients who received curative resection, 967 patients were lymph node-negative. Independent prognostic factors for overall survival in lymph node-negative gastric cancer patients grouped by tumor invasion depth (early gastric cancer versus advanced gastric cancer) were explored with univariate and multivariate analyses. Results: There was a significant difference in the distribution of recurrence pattern between lymph node-negative and lymph nodepositive group. In the lymph node-negative group, the recurrence pattern differed by the depth of tumor invasion. In univariate analysis for overall survival of the early gastric cancer group, age, macroscopic appearance, histologic type, venous invasion, lymphatic invasion, and carcinoembryonic antigen level were significant prognostic factors. Multivariate analysis for these factors showed that venous invasion (hazard ratio, 6.695), age (${\geq}59$, hazard ratio, 2.882), and carcinoembryonic antigen level (${\geq}5$ ng/dl, hazard ratio, 3.938) were significant prognostic factors. Multivariate analysis of advanced gastric cancer group showed that depth of tumor invasion (T2 versus T3, hazard ratio, 2.809), and age (hazard ratio, 2.319) were prognostic factors on overall survival. Conclusions: Based on our results, independent prognostic factors such as venous permeation, carcinoembryonic antigen level, and age, depth of tumor invasion on overall survival were different between early gastric cancer and advanced gastric cancer group in lymph node-negative gastric cancer patients. Therefore, we are confident that our results will contribute to planning follow-up strategies.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.66 no.9
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• pp.1379-1384
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• 2017

To guarantee safety and reliability, RAMS(Reliability Availability Maintainability and Safety) activity for a communication software in train communication network is studied. In this paper, preliminary hazard analysis in RAMS activities is studied for the communication software. Preliminary hazard analysis is done through library for communication software that the specification is defined by IEC 61375. The hazards are defined, then causes and consequence for each hazard are defined. The total 36 preliminary hazards are classified. For high severity hazards are changed to acceptable level by upgrading of system requirement specification.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.12 no.1
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• pp.29-42
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• 1992

Presented is a study on the development of seismic hazard analysis techniques to determine a reasonable design earthquake. To this end, the methods of seismic hazard analysis are first derived and the earthquake occurrence models are established. The present method yields the appropriate level of seismic hazard for any specific site. The characteristics of each hazard model are compared. The seismic hazards for several important sites where some nuclear power plants were installed are evaluated on the basis of the present models. The present study allows more realistic determination of design earthquakes at any specific sites for the design of major structures.

• The Transactions of the Korean Institute of Electrical Engineers P
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• v.64 no.3
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• pp.97-103
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• 2015

To achieve the safety and reliability, RAMS activity for a railway signal system of Near Surface Transit is studied. In this paper, preliminary hazard analysis in RAMS activities is studied for the railway signal system of Near Surface Transit. Preliminary hazard analysis is done through automatic train protection, automatic train operation and automatic train supervision. The hazards are defined, then causes and consequence for each hazard are defined. The total 75 preliminary hazards are classified. For high severity hazards are changed to acceptable level by upgrading of system requirement specification.

• Spatial Information Research
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• v.17 no.1
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• pp.25-37
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• 2009

In this paper, we propose techniques for hazard analysis of curved road based on USN. The techniques consist of models and algorithms. Models of curved road, road direction, sensor, vehicle and hazard are proposed. To analyze hazard in curved road and give warning to corresponding vehicle in realtime multi-level algorithms are proposed. An application program implements the models and algorithms to simulate proposed techniques with real-time visualization.