• 한국수정란이식학회지
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• 제22권2호
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• pp.127-135
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• 2007

본 연구에서 Holstein 유우 78두로부터 분만 후 9주까지 1주 간격으로 혈액과 우유를 채취하여 cholesterol, glucose, 광물질(selenium, Ca, p), vitamin E 및 혈장내 progesterone을 분석하여, 이들 성분의 변화와 성분간의 상관 관계 및 변화 요인에 관하여 조사하였으며, 결과는 다음과 같다. 1. 분만 후 9주까지의 각 성분별 평균 수준은 혈액에서 cholesterol, glucose, selenium, Ca, P, vitamin E 및 BUN이 각각 78.8 mg/dl, 62.3 mg/dl, 8.9mg/dl, 7.4 mg/dl, 52.2 ng/ml, $10.3{\mu}g/l$ 및 16.3 mg/dl이었으며, MSe와 MUN은 15.3 ng/ml과 15.8 mg/dl이었다. 2. 혈액내 cholesterol, glucose, selenium, Vitamin E 및 MSe는 분만 후 시일 경과에 따라 증가되었다. 3. 성분간의 유의적 상관관계를 보면 cholesterol은 P와 부(-), selenium과 U과는 정(+)의 상관이 었고, glucose는 P, MSe와 정(+), P는 selenium 와 부(-) 상관이었으며 그리고 BUN과 MUN은 정(+) 상관을 나타내었다. 4. 성분 변화의 요인으로서 유우 나이는 glucose와 selenium, 산차는 selenium과 vitamin E, 유량은 glucose와 MSe 수준에 차이가 나타났으며 청초와 건초 급여간에는 혈액내 Ca와 selenium를 제외 한 성분에서 차이를 보였다. 요소태 질소에서는 MUN에서만 나이와 산차간에 차이가 있었다. 이상의 결과로 분만 후 급여 사료에 따라 혈액 및 우유의 성분에 차이를 보이며, 특히 혈액 및 우유내의 selenium은 분만 후 젖소에는 중요한 요소임을 확인할 수 있었다.

• Preventive Nutrition and Food Science
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• 제4권1호
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• pp.62-69
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• 1999

The present study was aimed at investigating whether there are sex-related differences in serum levels of lipids, retinol , $\alpha$-tocopherol and ascorbic acid in Korean adults. Serum levels of antioxidant vitamins and lipids were determined algon with anthropometric measurements in 53 healthy male subjects with mean age 42.7$\pm$12.2 years and 44 female subjects with mean age 46.7$\pm$10.3 years. from Taegu in Korea. BMI and W/H ration of the men were 22.66$\pm$2.47, 0.88$\pm$0.04 and those fo thewomen were 23.36$\pm$3.44, 0.84$\pm$0.05 respectively. Systolic and diastolic blood pressures were 121.67$\pm$14.8, 79.3$\pm$12.4 in the men and 123.1 $\pm$17.5 , 78.8$\pm$10.9 in the women respectively. Average serum levels of total cholesterol, LDL-and HDL-cholesterol and triglyceride were 165.8$\pm$36.4, 102.6$\pm$31.2, 41.1$\pm$10.5 and 110.2$\pm$57.8mg/dl in the and 169.1$\pm$39.1, 113.7$\pm$36.2, 38.1 $\pm$8.6, and 85.2$\pm$37.7mg/dl in the women respectively. Thirteen percent of menans thirtyeight percent of women had LDL-cholesterol over 130mg/dl. Serum levels of retinol, $\alpha$tocopherol, ad ascorbic acid were 43.25 $\pm$15.51, 17.93$\pm$7.07, 115.24$\pm$63.25ug/dl in the men and 31.80$\pm$15.39, 17.41$\pm$6.12, an d144.99$\pm$89.87ug/dl in the women respectively. Serum vitamin E showed positive correlations with total cholesterol and LDL-cholesterol and triglyceride.

• Asian-Australasian Journal of Animal Sciences
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• 제15권10호
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• pp.1403-1411
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• 2002

The aims of this study were, firstly, to analyze the biochemical compositions of serum and follicular fluid (FF) from prepubertal gilts after PMSG (1,000 IU) treatment. The concentrations of total proteins, lipids, cholesterol, glucose and sex hormones (progesterone, $P_4$; estradiol-$17{\beta}$, $E_2$; testosterone, T) were measured. Secondary, the effects of porcine FF (pFF) addition (40% and 100%) in IVM media and different culture conditions [Exp. 1: mBMOC-2+20% porcine serum (PS), fresh IVM medium, filtered IVMconditioned medium, or rabbit oviducts; Exp. 2: mBMOC-2+20%PS or stepwise medium replacement procedures (SMRP) cocultured with or without cumulus cells] on the in vitro development (IVD) of porcine oocytes were also examined. Results showed that no significant differences were found in total protein levels between serum and pFF from different sizes (large, >7 mm; medium, ~5-7 mm; small, <3-5 mm) of follicles (75-85 and 49-90 mg/dl; p>0.05). Total lipid concentrations remained constant in serum (395-472 mg/dl), and reduced significantly in the pFF from large follicles (287 mg/dl) at 132 h after PMSG treatment when compared to those at other time points (441-480 mg/dl). Basal cholesterol levels in serum and pFF at 12 h were similar (153-161 mg/dl), but increased at 36 h (186-197 mg/dl). Basal P4 and E2 levels in serum (0.1 ng/ml and 5.5 pg/ml) were low, but increased from 0.34 ng/ml and 12.13 pg/ml at 24 h to 0.81 ng/ml and 61.70 pg/ml at 98 h, respectively, after PMSG treatment (p<0.05). P4 levels increased linearly in pFF from large follicles during 12 through 132 h (138-1,288 ng/ml). A similar increase was also observed in $E_2$ levels (22-730 pg/ml) before 60 h post PMSG treatment, and then dropped afterwards (730-121 pg/ml). The development of the oocytes fertilized in 40% pFF-medium was greater than that in 100% pFF-medium group without gonaodtropin addition (31% vs 10%, p<0.05). However, both were lower than those in mBMOC-2+20%PS and in rabbit oviducts (p<0.05). When cocultured with cumulus cell monolayers, a greater cleavage rate was observed in the group cultured in filtered IVM-conditioned medium than the SMRP group (36% vs 18%, p<0.05). A similar phenomenon was also observed in the culture without cumulus cell monolayers (33% vs 19%, p<0.05). It is concluded that neither the fresh IVM nor filtered IVM-conditioned medium has positive effect on the IVD of oocytes. Coculture with cumulus cell monolayers and the SMRP were not beneficial to the development of IVF pig oocytes.

• 대한한방내과학회지
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• 제26권1호
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• pp.275-280
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• 2005

Hyperlipidemia is one of the major factors causing the atherosclerosis of coronary arteries and well-documented modifiable risk factors of stroke, especially of the ischemic type. For Insulin-Dependent Diabetes Mellitus sufferers, if blood sugar is appropriately maintained, lipid and lipoprotein are normal, but if blood sugar is inappropriately maintained or clinical Diabetic nephropathy induces metabolic disorder of lipid, then Total cholesterol, low density lipoprotein cholesterol, triglyceride and very low density lipoprotein cholesterol levels go up and high density lipoprotein levels go down. The purpose of this study is to evaluate the effect of treatment with Ojeok-san and to observe the changes in Fasting Blood Sugar(FBS), 2 Hours Postprandial Blood Sugar(PP2h), Haemoglobin A1c(HbA1c), Total Cholesterol(T-Chol) and Triglyceride(TG). After the treatment, Fasting Blood Sugar decreased from 149mg/dl to 89mg/dl. 2 Hours Postprandial Blood Sugar decreased from l85mg/dl to 110mg/dl. Haemoglobin A1c decreased from 6.3% to 5.7%. Total Cholesterol decreased from 268mg/dl to 217mg/dl. And Triglyceride decreased from 438mg/dl to 265mg/dl. These results support a role for oriental medical therapy in treating Diabetic Hyperlipidemia. Further case studies of herbal treatment of this ailment are needed.

• 대한의생명과학회지
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• 제8권4호
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• pp.275-282
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• 2002

This study was carried out to investigate the effect of fibrinogen genotype and other characteristics on the plasma fibrinogen levels. Many studies have conformed that high plasma fibrinogen levels are associated with the increased risk of ischaemic heart disease, stroke and arterial disease. And fibrinogen levels are related with age, obesity, cholesterol and alcohol consumption, genotypes. For this study the blood samples were collected from 93 healthy Koreans (66 males and 27 females). The blood samples were individually analyzed by smoking status, cholesterol levels, genotype, age, and gender. The plasma fibrinogen was assayed by clotting method (modified Clauss assay) and cholesterol was assayed by cholesterol oxidase method. Subjects were classified by current smokers, ex-smokers (<6 month), or nonsmokers. The $\beta$-fibrinogen genotype was detected by PCR of relevant region and digestion with HaeIII, with the H$_1$H$_1$ allele allowing cleavage by this restriction enzyme and H$_2$H$_2$ allele being refractory. In conclusion, the study shows that the factor of the increasement in the fibrinogen level was closely related with the cholesterol level, smoking status and genotype (H$_1$H$_2$); but there was no significant difference by gender, Especially, among the people over 50 years of age, fibrinogen level was higher with the increasement of cholesterol level (<200 mg/dl), current smoker, and genotype H$_1$H$_2$.

• Journal of Preventive Medicine and Public Health
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• 제26권3호
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• pp.387-399
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• 1993

This study was conducted to analyze blood lipid profile and other risk factors among crew members who are currently active and had more than 10 years of experience as crew members. Data was analyzed using medical record files in an airline medical department. The results are as follows. 1. The total number of crew members studied was 392. Among age groups, those below age 40 consisted of 26(6.9% of the total), those in age $41{\sim}50$ were 135 (34.4%) and those over age 51 were 230 (58.7%). 263 were former air force pilots consisting 66.9%. Those who had captain status numbered 21 I comprising 53.7% of the total. The type of aircraft most of the crew members involved were large size aircraft which totaled 268 (68.2%). With respect to the number of working years as crew members, 488(48.9%) comprised the largest group with $11{\sim}15$ years. 2. The rate of smoking among crew members has shown gradual decrease with 50.3% smoking in 1983 to 33.6% in 1993. Among $41{\sim}50$ age group the rate has shown a decrease from 20.9% to 13.3% In those group over age 51 it decreased from 25.5% to 16.6%. But group below age 40 were within the range of 3.6~3.8% with no significant change in the rate of smoking. 3. Body Mass Index in age group over 51 was slightly higher than other age groups. On the whole, BMI over 25 was not found. 4. The total cholesterol levels of those below age 40 were $196.9{\pm}38.5mg/dl,\;216.2{\pm}39.2mg/dl$ in ages $41{\sim}50$, and $225.1{\pm}42.5mg/dl$ in age group over 51. No significant difference was found among age groups. 5. HDL-cholesterol levels of over age 50 were higher than other age group and ranged from $40{\sim}55mg/dl$. 6. LDL-cholesterol levels of those over 51 were $126.7{\pm}37.7mg/dl$ higher than other age groups. But there were no significant changes in all age during 10 years of follow up. 7. Cardiac index of age group below age 40 was 3.8, 4.3 in age group $41{\sim}50$ and 4.5 in those over age 51 group. No significant changes among groups were found during the follow up period. 8. Triglyceride levels of age group below age 40 was $142.2{\pm}70.1,\;167.3{\pm}77.5$ in age group of $41{\sim}50$ and $113.6{\pm}897$ in age group over 50 showing that triglyceride levels increased with age. No significant changes in pattern were noted.

• 셀메드
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• 제10권4호
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• pp.31.1-31.6
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• 2020

Introduction: Dyslipidaemia is directly associated with cardiovascular diseases. Temperament, the unique constitutional make-up of an individual, is responsible for one's personality traits, physical appearances, and disease predispositions. The rising prevalence of dyslipidaemia becomes a challenge to control morbidity and mortality due to cardiovascular diseases. Objective: To study clinical patterns and risk factors of dyslipidaemia and its association with temperament at the individual level was the main objective of this study. Materials and Methods: It was a descriptive and analytical cross sectional study. The participants (n=88) were screened on the basis of raised serum lipid profile from the outpatient department of National Research Institute of Unani Medicine for Skin Disorders, Hyderabad. The data were collected on a case record form designed for this study and analyzed retrospectively. Results: In this study, there were 57% participants (n=50) of phlegmatic temperament in which mean total cholesterol, triglycerides, low density lipoprotein- cholesterol and high density lipoprotein-cholesterol were 230.92 (±49.48) mg/dl, 182.34 (±110.61) mg/dl, 153.24 (±50.21) mg/dl and 46.3 (±10.83) mg/dl respectively. Discussion: This study showed the prevalence of different clinical patterns of dyslipidaemia in the population and the phlegmatic participants were dyslipidaemic in a higher percentage. The prevalence of dyslipidaemia in phlegmatic participants may be linked to the constitutional make-up of the individual. The temperament of an individual may be considered as one of the risk factors for dyslipidaemia. Conclusion: It was concluded that the temperament of an individual may be used as a screening tool to predict the individual's tendency to develop dyslipidaemia.

• Asian-Australasian Journal of Animal Sciences
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• 제17권5호
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• pp.648-654
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• 2004

This study was carried out to assess whether feeding of alcohol-fermented feeds (AFF) affects the nutritional metabolism and growth characteristics of Korean native steers. Ten steers were randomly assigned to one of two treatment groups. The dietary treatments were AFF (50% commercial beef cattle feed+30% alcohol-fermented soybean curd dregs+20% rice straw) and control (80% commercial beef cattle feed+20% rice straw). The change of serum metabolites and growth characteristics were measured every two months during the whole twelve months experimental period and the relationships between serum metabolites and growth characteristics were simultaneously analyzed. Four hours after feeding AFF, serum alcohol concentration reached its peak with a significantly higher value than that after control feeding (11.9 and 4.9 mg/dl, respectively). Serum glucose and inorganic phosphorus (IP) concentrations (63.1 and 8.4 mg/dl, respectively) of steers fed AFF were higher than those (56.6 and 7.0 mg/dl) fed the control diet. In both treatments, the serum glucose concentration rapidly increased when body weight (BW) of the steer reached about 600kg, while IP concentrations were rapidly diminished at that BW. Lower concentrations of both blood urea nitrogen (BUN) and cholesterol were observed in steers fed AFF up to 450 kg of BW. The IP concentration was correlated with concentrations of BUN, cholesterol and glucose in AFF fed cattle but not in the cattle fed control diets. Average daily gain was higher in steers fed AFF than steers fed control, particularly during the growing stage of cattle. These findings indicated a capability of AFF to improve BW gain of Korean native steers by decreased protein degradation as well as increased fat synthesis.

• Journal of Nutrition and Health
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• 제35권8호
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• pp.854-862
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• 2002

In the present study, we investigated the effects of chronic green tea consumption on the serum lipid profiles of 92 subjects (mean age: 59.5 $\pm$ 8.9, men: 41, women:51) living in a green tea cultivation village. The anthropometric and biochemical blood indices were measured, and nutritional intakes were assessed using 24-h recall method. Also, we administered a questionnaire regarding green tea consumption. The subjects were divided into three groups based on the period of green tea consumption (0, < 10 year, and $\geq$ 10 year). There were no significant differences in age, anthropometric indices (Wt, Ht, BMI, Body fat, LBM), and nutritional intakes among the groups. Serum LDL-cholesterol concentration was significantly lower in the $\geq$ 10 year group compared with the other groups (p < 0.05). Also, the LDL/HDL-cholesterol ratio was significantly lower in the $\geq$ 10 year group compared with the other groups (p < 0.05). The frequency of subjects with a normal range of serum LDL-cholesterol concentration (< 200 mg/dl) was significantly higher in the $\geq$ 10 year group compared with the other groups (p < 0.05). These results imply positive effects of chronic green tea consumption on blood lipid profiles, which requires confirmation in further studies.

• 한국식품영양학회지
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• 제9권2호
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• pp.201-212
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• 1996

The purpose of this study was to find an effect of honey on the lipid metabolism of Sprague Dawley rats. All experimental rats were fed ad libitum, for seven weeks, 68% saccharide diet and 10% or 20% honey from acacia, sumac and miscelllaneous flower honey, respectively, and sucrose. The food efficiency ratio of rat taken diet with honey and high fructose of control group was increased in comparison with the control group. The concentration of cholesterol in serum of rats take총 diet with and high fructose of control group was more increased in comparison with the control and normal group. The concentration of H DL-cholesterol in serum of rats taken sumac honey was increased 57.0% in comparison with the control group, but the concentration of VLDL, LDL-cholesterol in serum of rats taken diet 10PA sumac honey was decreased 48.36% in comparison with the control group. The concentration of phospholipid in serum of rats taken diet with 20% acacia or 10% miscellaneous honey was increased 24.7, 16.25%, respectively, in comparison with the control group. The concentration of free fatty acid in serum of rats taken Inlet with sumac or miscellaneous honey and high fructose was increased in comparison with the comparison with the control group. The concentration supplemented diet with acasia honey was increase in comparison with the control group. The concentration of triglyceride in serum of rat was increased by feeding of honey. The concentration of triglyceride in liver was increased, but the level of phospholipid was decreased by feeding of honey.