• Title/Summary/Keyword: gums

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Anti-inflammatory Effect of Boswellia sacra (Franckincense) Essential Oil in a Mouse Model of Allergic Asthma (알러지성 천식 모델 생쥐에서 프랑킨센스 에센셜 오일의 염증 억제 효과)

  • Lee, Hye-Youn;Yun, Mi-Young;Kang, Sang-Mo
    • Microbiology and Biotechnology Letters
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    • v.36 no.4
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    • pp.343-352
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    • 2008
  • Frankincense, the gum resin derived from Boswellia species, is complex mixtures composed of about $5{\sim}9%$ highly aromatic essential oil, $65{\sim}85%$ alcohol-soluble resins, and the remaining water-soluble gums. The anti-inflammatory properties of frankincense, alcohole-soluble resins, are well-recognized, but the question of whether aromatic essential oil also plays a role in the allergic asthma remains unanswered. This study was performed to evaluate anti-inflammatory effects of Boswellia sacra essential oil (BSEO) on ovalbumin (OVA)-induced asthma mouse model. BALB/c mice after intraperitoneal OVA sensitization were challenged with intratracheal OVA. One experimental group was inhaled with 0.3% BSEO for the later 8 weeks. BALB/c mice were sensitized and challenged with OVA and developed airway eosinophilia, mucus hypersecretion, and airway hyperresponsiveness. In contrast, the BSEO treated mice had reduced a number of eosinophils among BALF cells, goblet cell hyperplasia, and airway hyperresponsiveness. Cytokine analysis of BALF revealed that BSEO caused an increase in Th1 cytokine (interferon-$\gamma$ (IFN-$\gamma$)) and a decrease in Th2 cytokines (interleukin-4 (IL-4), IL-5 and IL-13) levels. In addition, the OVA-specific serum IgE and eotaxin levels were also reduced. In mice inhaled BSEO, $CD4^+$, $CD3^+/CCR3^+$, and $B220^+/CD23^+$ mediastinal lymph nodes cells were also decreased. These results suggest that inhaled BSEO as a immunomodulator in Th1/Th2 mediated asthma may have therapeutic potential for the treatment in allergic airway inflammation by a simple, cost-effective way.

Method for Increasing the Stability and Activity of Polygalacturonase and Its Application to the Production of Vegetable Single Cell (Polygalacturonase의 활성 증진 및 이를 이용한 식물 단세포 제조 방법)

  • Kim, Hyuk-Hwa
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.36 no.12
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    • pp.1633-1636
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    • 2007
  • This study was carried out to enhance the stability and activity of polygalacturonase (PGase) purified from Kluyveromyces marxianus IFO 0288. Gums such as xanthan gum, guar gum, and locust bean gum were capable of increasing the catalytic stability and activity of the PGase. At $30^{\circ}C$, the rate constants for the inactivation of the PGase with xanthan gum, guar gum, and locust bean gum were estimated to be $0.0003min^{-1}$, below $0.0001min^{-1},\;and\;0.0001min^{-1}$ respectively, whereas control was estimated to be $0.0082min^{-1}$. The yield of the maceration reaction catalyzed by the PGase for the production of carrot single cells increased by 13% in the presence of guar gum, where the relative enzyme activity supplemented with guar gum was two-fold greater than that of the PGase alone.

Influence of Daily Stress to Oral Symptoms among Adults (성인의 생활스트레스가 구강증상에 미치는 영향)

  • Hong, Min-Hee
    • Journal of dental hygiene science
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    • v.13 no.1
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    • pp.20-28
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    • 2013
  • Daily stress is emerging as one of major problems to affect oral health in complicated and diversified modern society. The purpose of this study was to examine the influence of the daily stress of adults on their oral symptoms. The subjects in this study were 460 adults, on whom a survey was conducted from July 1 to October 30, 2012. The findings of the study were as follows: As to the impact of daily stress on oral symptoms, symptoms of the lips and cheeks and symptoms of the tongue were under the significant influence of physical, behavioral and psychoemotional stress. Physical and psychoemotional stress had a significant impact on symptoms of the teeth and the gums, and temporomandibular symptoms were significantly affected by psychoemotional and physical stress. The findings of the study showed that daily stress exerted a larger influence on the lips, cheeks and mucous membrane of oral cavity, and that multiple oral diseases took place when there were not only physical and psychoemotional stress but behavioral stress.

Predicting tobacco risk factors by using social big data (소셜 빅데이터를 활용한 담배 위험 예측)

  • Song, Tae Min;Song, Juyoung;Cheon, Mi Kyung
    • Journal of the Korean Data and Information Science Society
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    • v.26 no.5
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    • pp.1047-1059
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    • 2015
  • This study will predict risk factors associated with cigarettes in Korea by analyzing the social big data collected from the internet such as blogs, cafes, and SNSes in Korea, using data mining techniques. The key analysis results are as follows. First, when "raising cigarette price"is mentioned online, the negative group (i.e., the proportion of people holding negative views about smoking) increased from 58.6% to 74.8%, and when "lung cancer" is mentioned, it increased to 73.1%. Second, with regard to cigarettes in general, the positive group (i.e., the proportion of people holding positive views about smoking) decreased by 5.6% after the raising of cigarette prices, while the negative group increased by 6.1%. Third, when policies related to "FCTC, raising cigarette price, non-smoking laws, smoking regulations, non-smoking ads, and nonsmoking business" are more frequently mentioned online, the positive group tended to decrease. Finally, when "non-smoking drugs, non-smoking patches, and non-smoking gums" are more frequently mentioned online, the positive group tended to decrease. However, when "electronic cigarettes and supplements" are more frequently mentioned online, the positive group increased.

Tooth whitening effect of toothpaste containing hydrogen peroxide (과산화수소가 배합된 제제의 치아미백효과에 관한 연구)

  • Ahn, Jae-Hyun;Kim, Ji-Hye;Kim, Jong-Hoon;Jang, Jong-Hwa;Oh, Yoon-Jong;Park, Yong-Duk
    • Journal of Korean society of Dental Hygiene
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    • v.14 no.1
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    • pp.101-108
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    • 2014
  • Objectives : The purpose of this study was to evaluate the tooth whitening effect of 0.74% and 2.80% hydrogen peroxide toothpastes and safety on tooth and gingival tissue. Methods : Toothpastes containing 0.74% and 2.80% hydrogen peroxide were evaluated. In in-vitro test, some additives (sodium metaphosphate, sodium pyrophosphate and titanium dioxide) were added to the toothpastes. Hydroxyapatite specimens (HAPs) were made and stained using modified Stookey's methods. HAPs were treated for 1 hour at shaking incubator and brushed for 1,000 times as 250 gF with each diluted toothpaste. Before and after color was measured by colorimeter. Using double blind method, 99 Korean with natural maxillary anterior teeth were selected and the initial brightness (baseline) was measured by SHADEEYE-EX. Based on this measurement they were crossly distributed into control group (0% hydrogen peroxide), test 1 (0.74% hydrogen peroxide) and test 2 (2.80% hydrogen peroxide). After 2 weeks, people of each group were provided toothpaste and told to use 3 times a day right after every meal for 3 minutes. The brightness of teeth was measured 3 times for every one month. Results : ${\Delta}L$ was statistically significant among three groups in shaking test. ${\Delta}L$ of two test groups was statistically significant compared with control group but not between each test group in brushing test. After using toothpaste for 3 months, test 1 group and test 2 group were 15.89% and 31.23% more whitened compared with control group respectively (p<0.05). Rate of more whitened person of each test group was 24.2% and 40.5% more than control group respectively (p<0.05). There was no difference in the hypersensitivity during 3 months using toothpastes and no side effect on teeth or gums. Conclusions : Toothpastes containing 0.74% and 2.80% hydrogen peroxide showed tooth whitening effect and both were safe enough to use for tooth whitening.

A study on the relationship of general characteristics to behavioral reaction toward oral malodor (영역별 특성에 따른 구취발생시 행동대처에 관한 연구)

  • Jang, Gye-Won;Park, Sung-Suk
    • Journal of Korean society of Dental Hygiene
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    • v.9 no.3
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    • pp.493-506
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    • 2009
  • The purpose of this study was to examine the awareness of people in general characteristics about oral malodor. The subjects in this study are 184 people who visited the clinical practice lab at J health college to get their teeth scaled. After conducting a survey from May 1 to June 3, 2008, we selected four different ares and then analyzed the answer sheets from 179 respondents including smoking/nonsmoking, scaling experience, toothbrushing frequency and the use of oral hygiene supplies. SPSS WIN 12.0 program was used to make a frequency analysis and cross analysis. The findings of the study are as follows: 1. Concerning an intention of treatment for oral malodor, 37.4% didn't intend to receive treatment even in case of having bad breath. 28.5% didn't yet have any definite idea about that, and 20.7% had no mind to do that at all. 10.6% had an intention to receive treatment, and 2.8% want to receive treatment. 2. As for how to cope with oral malodor in case of suffering from it, 47.5% chewed gums or ate candy. 25.1% scarcely care about that, and 15.6% covered their mouth whenever they spoke. 9.5% had little confidence about talking to others, and 2.2% found it difficult to build an amicable interpersonal relationship. 3. Concerning what to do about another person's oral malodor, 40.8% did nothing, and 19% talked to the person about that. 17.3% gave him or her chewing gum. Among their oral health characteristics, toothbrushing frequency made a significant difference to the way they responded to another person's oral malodor(p<.05). 4. As to subjective feelings about another person's oral malodor, 41.9% just found it bearable. 36.9% were a little displeased, and 9.5% never felt bad about another person's bad breath. 8.9% tried to avoid the person, and 2.8% advised him or her to chew gum. 5. Regarding an intention of participating in a oral malodor program, 46.9% had no idea about that. 31.3% intended to participate in the program, and 13.4% wanted to do that without fail. 6.1% had no mind for that, and 2.2% were never going to do that. Among characteristics of the user oral hygiene device made a significant difference whether to participating in the oral malodor program(p<.05).

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Related factors of oral symptoms in adolescents from Korean multicultural families (우리나라 다문화가정 청소년의 구강질환증상과의 관련요인)

  • Han, Yeo-Jung;Park, Sin-Young;Ryu, So-Yeon
    • Journal of Korean society of Dental Hygiene
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    • v.16 no.6
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    • pp.893-907
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    • 2016
  • Objectives: The purpose of this study was to identify the related factors of dental caries and periodontal disease in adolescents from Korean multicultural families, thereby helping to reduce the prevalence rate of oral disease. Methods: The subjects were 710 multicultural adolescents recruited using a web-based survey, National 2015 Korean Youth Risk Behavior, from the Korean Center for Disease Control. A multicultural family was defined in this study as one having an immigrant mother or father. Oral symptoms included dental caries and periodontal disease. Toothache was defined as a symptom of dental caries. Tender or bleeding gums were defined as symptom of periodontal disease. For statistical analysis, Statistical Package for Social Sciences (SPSS) Version 21.0 for Windows was used. Descriptive analysis and a Chi-square test were conducted to determine the factors associated with general characteristics, health behavior, and oral health behavior. Finally, to investigate the associations among oral disease symptoms, logistic regression analysis was performed. Results: Toothache was significantly higher in female 1.52 (95% CI; 1.45-1.60), high school 1.23 (95% CI; 1.18-1.28), women school 1.10 (95% CI; 1.05-1.16), individuals with poor economic status 1.45 (95% CI; 1.30-1.52), and participants who consumed alcohol 1.32 (95% CI; 1.27-1.37). Toothache related to perceived health status was significantly lower in the healthy group 0.69 (95% CI; 0.64-0.75), and was higher in usual stress group 1.65 (95% CI; 1.57-1.74). Gum bleeding was significantly higher in female 1.32 (95% CI; 1.27-1.37), high school 1.15 (95% CI; 1.10-1.19), and individuals with poor economic status 1.38 (95% CI; 1.27-1.50). Gum bleeding related to perceived health status was significantly lower in the healthy group 0.68 (95% CI; 0.63-0.74), and was higher in usual stress group 1.54 (95% CI; 1.46-1.62). Conclusions: Taking into account of social and economic levels, and dietary habits in the multicultural families adolescents, further education and support will be needed for oral disease prevention and early treatment.

Structure/Property of Adhesives and Adhesion Performance (접착제의 구조물성과 접착특성)

  • Hiroshi Mizumachi
    • Journal of Korea Technical Association of The Pulp and Paper Industry
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    • v.29 no.1
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    • pp.73-83
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    • 1997
  • Most of the materials used in various industrial fields and also in our daily life are multi-component materials or composite materials, and it is well known that there are many cases where adhesion between the constituents within the bonded systems plays an important role. There are various types of performance evaluation tests for the bonded materials, among which tests for evaluating the bond performance under various conditions may be regarded as the most interesting ones for those engaged in work related to adhesion. I have studied on the mechanism of adhesion form the rheological standpoint with my colleagues, including some students from Korea, and I am very happy to be able to have a talk on some of our research works. In Japan, the so-called "adhesives" are usually classified into two categories;adhesives and pressure sensitive adhesives (PSA). Adhesives are the materials which solidify after bonding and are after used as the structural adhesives because the adhesive strength is comparatively strong. On the other hand, the pressure sensitive adhesives never solidify and are used as PSA tapes, labels or decals. About the adhesives, we have examined the dependence of adhesive strength(shear, tensile, peel) upon both temperature and rate of deformation, and found out some empirical rules which are applicable to most of the adhesive systems. We have also developed a simplified theory of adhesion, which is deseribed in terms of mechanical equivalent mode1 and a few failure criteria. Although some of the common rules can be accounted for according to this theory, it must be pointed out that a fracture mechanical approach ms inevitable especially in the region where the meehanical relaxation time of the adhesive is extremely large [W. W. Lim and H. Mizumachi]. About the pressure sensitive adhesives, we have studied on the PSA performance (peel, tack, holding power) as a function of both the viscoelastic properties and surface chemical properties of the materials, and found out some rules, and again we have developed a theory which deseribes the mechanism. And in addition, we have studied on the miscibility between linear polymers and oligomers, because PSA is generally manufactured by blending gums and tackifier resins. Many phase diagrams have been found and some of them have been analyzed on thermodynamic basis, and it became evident that the miscibility is a very important factor in PSA [H. J. Kin and H. Mizumachi]. In this presentation, I want to emphasize the fact that the adhesion performance is closely related to the structure/property of the adhesives.adhesives.

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Suppression of Solid Matters Precipitation of Takju and Its Quality Improvement by Carrageenan (Carrageenan에 의한 탁주 고형물 침전 억제 및 품질 개선에 관한 연구)

  • Park, Hyun-Jeong;Shin, Wan-Chul;Song, Jae-Chul
    • The Korean Journal of Food And Nutrition
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    • v.19 no.3
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    • pp.288-295
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    • 2006
  • This study was conducted to examine the possibility of improvement effect in suppression of precipitation and nasty smell creation in Takju mash. First of all, gum shown to be lowest precipitation velocity was selected and this was applied to the fermentation of Takju mash for comparing with the control in terms of fermentation aspects and various qualities of Takju mash. Precipitation amount and precipitation velocity of suspension in Takju mash added with carrageenan was shown to be the lowest than that of others. Compared with the control, alcohol was highly generated in Takju mash added with carrageenan, especially between two and four days. Total acidity was shown to be highly increased until 2 days in Takju mash and thereafter to be slightly increased. Takju mash added with carrageenan was shown to be lower on the second stage than the control. Fusel oil produced from mash added with carrageenan was 0.046${\sim}$0.113${\mu}$l/ml and mash added with carrageenan generated less fusel oil than the control by 1.6${\sim}$3.2 fold. Yeast growth on the mash added with carrageenan was revealed to be helpful during fermentation periods. In general, sensory characteristics of Takju mash were shown to be more superior in mash added with carrageenan than in other samples. While nasty smell produced from a sample without gums was perceived after 2 days of Takju mash storage, nasty smell of Takju mash added with carrageenan was recognized after 6 days during storage. In conclusion, precipitation of suspension and nasty smell production in Takju mash were found to be suppressed by addition of carrageenan during Takju fermentation.

The Effect of Middle Schoolers' Oral Health Awareness on Oral Health Condition and Oral Health Behavior (중학생들의 구강보건인식이 구강건강상태와 구강건강행위에 미치는 영향)

  • Cho, Eun-Suk
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.14 no.10
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    • pp.5020-5028
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    • 2013
  • The purpose of this study is to investigate the effects of awareness of oral health on oral health status and oral health behavior with subjects of students in the middle school which is the important period when lifetime set of teeth is completed with eruption of the second molar tooth and complete set of permanent teeth, and provide the basic data for development of oral health program for adolescents. We examined oral condition and conducted the survey about students' awareness of oral health and behavior in the middle school located in JeonJu. As the results of oral examination, dental caries and malocclusion were higher in female students and periodontal disease was higher in male students (p < 0.038). There was no significant difference in awareness of oral health between male and female students. However, M = 4.08 out of 5 point scale, which was high. For oral health behaviors, female students (M = 4.508) was higher than male students (M = 4.257) in the question of 'I visit the dental office when my gums are bleeding'. Female students (M = 4.547) was higher than male students (M = 4.333) in the question of 'I use the dental floss after brushing my teeth'(p<0.05). Awareness of oral health gave the significant effect on the oral health behavior at 95 % confidence level. Therefore, the education for oral health behavior is required to improve oral health and studies are needed to present the development of program for awareness and knowledge of oral health affecting behavior.