• 제목/요약/키워드: growth volume

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Transport Spillover Effect on Airport Networks and Its Impact on Regional Economy (운송 파급효과가 항공네트워크와 지역경제에 미치는 영향)

  • Xinchen Wang;Po-Lin Lai
    • Korea Trade Review
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    • v.47 no.4
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    • pp.35-52
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    • 2022
  • Air transport is at the core of global economic growth. There is a close relationship between the flow of regional elements and the growth of the regional economy. It is easy to misestimate the impact of airports on the regional economy without considering spatial spillover effects. This study attempted to establish an asymmetric economic geographical weight matrix by applying the Spatial Durbin Model with cargo volume and passenger numbers as indicators. The influence of spillover effects on the regional economy, including direct spillover effects and indirect spillover effects are studied. The results revealed that passenger numbers and cargo volume have significant positive spillover effects on the regional economy. The driving effect of the airport on the regional economy was considered from a wider space scope. This study contributes to the scientific evaluation of the aviation economy.

ANTI-TUMOR AND ANTI-ANGIOGENIC EFFECT OF THALIDOMIDE ON ORAL SQUAMOUS CELL CARCINOMA XENOGRAFTS IN NUDE MICE (누드마우스에 이종이식된 구강편평상피세포암종에 대한 thalidomide의 항암효과와 혈관형성억제에 관한 연구)

  • Kim, Su-Gon;Myoung, Hoon;Kim, Myung-Jin
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.27 no.4
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    • pp.330-336
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    • 2001
  • Angiogenesis is an essential process for the growth, invasion and metastasis of cancer. However, it is uncertain that antiangiogenic effects can be a major treatment strategy of oral cancer. The aim of this study was to investigate whether thalidomide, which is known to be a potent inhibitor of angiogenesis, have inhibitory effect on the growth and antiangiogenic effects of oral squamous cell carcinoma(OSCC) xenografted in nude mice and whether antiangiogenesis of thalidomide can be included as a major treatment strategy of oral cancer. After human oral squamous cell carcinoma strain KB was subcutaneously implanted in 20 nude mice, the volume of tumor was measured every three days. When the tumor mass reached $75{\sim}100mm^3$, thalidomide(200mg/kg/d) was administered into 10 experimental nude mice and the same volume of distilled water was administered into 10 control nude mice and the tumor volume was measured every three days. The excised tumor masses on the 30th day after administration were frozen and processed for immunohistochemistry using vascular endothelial growth factor(VEGF) and CD31. We evaluated microvessel density and VEGF expression. The results were as follows ; 1. Thalidomide retarded the growth of human OSCC as compared with the control group, but it was not statistically significant. 2. A statistically significant lower microvessel density was observed in the thalidomide-treated group than in the control group(p<0.01) and thalidomide significantly reduced VEGF expression (p<0.01). Thalidomide exhibited significantly antiangiogenic effect, but did not inhibit the growth of human OSCC effectively. Antiangiogenic therapy of thalidomide alone is not likely to be effective in the treatment of human OSCC, but might be regarded as adjuvant chemotherapeutic strategy.

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Effect of Microstructure on the Characteristics of Fatigue Crack Propagation of Super Duplex Stainless Steel (수퍼 2상 스테인리스강의 피로균열진전 특성에 미치는 미세조직의 영향)

  • 도재윤
    • Journal of Ocean Engineering and Technology
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    • v.14 no.2
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    • pp.65-69
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    • 2000
  • This study is to investigate the characteristics of fatigue crack propagation in rolled super duplex stainless steel that was changed austenite-ferrite volume fraction by heat treatment. It was used two kinds of specimen the rolling and the transverse directions δ-phase fraction affected sound velocity hardness and Young's modulus. Characteristics of fatigue crack propagation was affected by anisotropy and (δ+γ) phase volume fractions.

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Effect of the Environmental and Nutritional Conditions on the Growth of Marine Microalga Isochrysis Galbana Parke (해양 미세조류 Isochrysis galbana Parke 성장에 대한 환경 및 영양 조건의 영향)

  • 오유관;박성훈
    • KSBB Journal
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    • v.11 no.3
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    • pp.303-310
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    • 1996
  • The marine microalga Isochrysis galbana Parke was studied to optimize its growth conditions in flask culture. Important medium components studied include nitrogen source, buffer, trace elements and vitamins. Environmental conditions include pH, temperature, light intensity, mixing extent and working volume. The medium prepared from natural sea-waters gave a higher final cell density than the medium prepared from synthetic sea-water Nitrate was a better source than ammonium. In the range of 0.4∼2mM, the final cell density was proportional to the initial nitrate concentration and the cell yield was estimated to be 8.5g dry cell wt/g N. For phosphate, optimal growth was observed in 0.1∼1.0mM but a considerable variation in pH was resulted. The addition of Tris at 5mM or 7mM could stabilize the medium pH, but this significantly reduced both growth rate and final cell density, The effect of trace elements and vitamins was negligible. Optimal temperature and initial pH were $20^{\circ}C$ and 8. When the intensity of incident light was varied in the range of 400∼2100 lux, the growth rate increased from 10mL to 70mL, the final cell density decreased although the initial growth rate did not change. Optimal agitation speed was 100rpm when working volume was 30mL. With optimal conditions, the maximum specific growth rate obtained was 0.021hr-1 and the final cell density was 1.1g/L.

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The Effects of growing media and irrigation methods on the growth of hot pepper(Capsicum annuum) transplants (배양토 종류와 관수방법이 고추묘의 생육에 미치는 영향)

  • 박권우;이정훈;원재희;장매희
    • Journal of Bio-Environment Control
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    • v.2 no.2
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    • pp.110-118
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    • 1993
  • This experiment was carried out to investigate the physical and chemical properties of growing media and to study the effects of growing media and irrigation methods on the growth of hot pepper(Capsicum annuum) transplants. The results were summarized as follows : 1. Growing media consisting of peatmoss and field soil at the volume ratio of 1 : 1, 1 : 2 showed suitable chemical properties for the growth of hot pepper transplant. 2. The germination rate of hot pepper in the sprinkler- irrigation was higher than that in the sub - irrigation. In the sprinkler irrigation, there was no difference of germination rate among the mixed growing media. 3. The growth of hot pepper transplant in the sub - irrigation was better than that in the sprinkler-irrigation. Peatmoss and field soil mixtures with the volume ratio of 1 : 1 and 1 : 2 showed the best growth condition.

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A Study on the Thermal Stability of Duplex High Mn-Steel Structure (고 망간강 2상 혼합조직의 열적 안정성에 관한 연구)

  • Wey, Myeong Yong
    • Journal of the Korean Society for Heat Treatment
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    • v.5 no.1
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    • pp.13-22
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    • 1992
  • The thermal stability of duplex high Mn-steel structure have been investigated using 15%Mn~1.0~2.4%C steels which are composed of ${\gamma}$-and ${\theta}$-phases in the range of temperature from 900 to $1100^{\circ}C$, and time from 50 to 300h. The results are as follows ; 1) The grain growth in single-phase region proceeds by grain boundary migration and the relation between mean radius $\bar{r}$ and annealing time t is described as follows ; $\bar{r}^2-{\bar{r}_0}^2=k_0{\cdot}t$ 2) The grain growth of duplex, (${\gamma}+{\theta}$), strucrure is slower than that single phase because the chemical composition of ${\gamma}$-and ${\theta}$-phases differs esch others. 3) The grain of (${\gamma}+{\theta}$) duplex structure grow slowly in a mode of Ostwald ripening. Because grain boundaries of ${\gamma}$-phase migrate under a restriction of pinning by ${\theta}$-phases. 4) In the duplex structures. the dispersed structures change to the dual-structures, as the volume fraction of the dispersed second-phase increase. Consequently, the growth-law, which is controlled by boundary-diffusion change to that of the volume diffusion-mechanism.

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Degradation analysis of horizontal steam generator tube bundles through crack growth due to two-phase flow induced vibration

  • Amir Hossein Kamalinia;Ataollah Rabiee
    • Nuclear Engineering and Technology
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    • v.55 no.12
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    • pp.4561-4569
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    • 2023
  • A correct understanding of vibration-based degradation is crucial from the standpoint of maintenance for Steam Generators (SG) as crucial mechanical equipment in nuclear power plants. This study has established a novel approach to developing a model for investigating tube bundle degradation according to crack growth caused by two-phase Flow-Induced Vibration (FIV). An important step in the approach is to calculate the two-phase flow field parameters between the SG tube bundles in various zones using the porous media model to determine the velocity and vapor volume fraction. Afterward, to determine the vibration properties of the tube bundles, the Fluid-Solid Interaction (FSI) analysis is performed in eighteen thermal-hydraulic zones. Tube bundle degradation based on crack growth using the sixteen most probable initial cracks and within each SG thermal-hydraulic zone is performed to calculate useful lifetime. Large Eddy Simulation (LES) model, Paris law, and Wiener process model are considered to model the turbulent crossflow around the tube bundles, simulation of elliptical crack growth due to the vibration characteristics, and estimation of SG tube bundles degradation, respectively. The analysis shows that the tube deforms most noticeably in the zone with the highest velocity. As a result, cracks propagate more quickly in the tube with a higher height. In all simulations based on different initial crack sizes, it was observed that zone 16 experiences the greatest deformation and, subsequently, the fastest degradation, with a velocity and vapor volume fraction of 0.5 m/s and 0.4, respectively.

The Interaction of Vortex and Premixed Flame with Consideration of Volume Expansion Effect (체적팽창효과를 고려한 예혼합화염과 와동의 상호작용에 관한 연구)

  • Jeong Ui-Heon;Gwon Se-Jin
    • 한국전산유체공학회:학술대회논문집
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    • 1998.11a
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    • pp.204-210
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    • 1998
  • A method is developed to include the effect of volume expansion in the description of the flame dynamics using G-equation. Line volume-source is used to represent the effect of the exothermic process of combustion with source strength determined by the density difference between the burned and the unburned region. Volume expansion adjusts the flow field to accommodate the increased volume flow rate crossing the flame front. Test result predicted the measured velocity field qualitatively. The method was applied to study the interaction of vortex and premixed flame. Increased volume expansion did not change the initial growth rate of flame area. However, the residence time and flame surface area increased with higher expansion ratios.

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Estimating Stand Volume Pinus densiflora Forest Based on Climate Change Scenario in Korea (미래 기후변화 시나리오에 따른 우리나라 소나무 임분의 재적 추정)

  • Kim, Moonil;Lee, Woo-Kyun;Guishan, Cui;Nam, Kijun;Yu, Hangnan;Choi, Sol-E;Kim, Chang-Gil;Gwon, Tae-Seong
    • Journal of Korean Society of Forest Science
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    • v.103 no.1
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    • pp.105-112
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    • 2014
  • The main purpose of this study is to measure spatio-temporal variation of forest tree volume based on the RCP(Representative Concentration Pathway) 8.5 scenario, targeting on Pinus densiflora forests which is the main tree species in South Korea. To estimate nationwide scale, $5^{th}$ forest type map and National Forest Inventory data were used. Also, to reflect the impact of change in place and climate on growth of forest trees, growth model reflecting the climate and topography features were applied. The result of the model validation, which compared the result of the model with the forest statistics of different cities and provinces, showed a high suitability. Considering the continuous climate change, volume of Pinus densiflora forest is predicted to increase from $131m^3/ha$ at present to $212.42m^3/ha$ in the year of 2050. If the climate maintains as the present, volume is predicted to increase to $221.92m^3/ha$. With the climate change, it is predicted that most of the region, except for some of the alpine region, will have a decrease in growth rate of Pinus densiflora forest. The growth rate of Pinus densiflora forest will have a greater decline, especially in the coastal area and the southern area. With the result of this study, it will be possible to quantify the effect of climate change on the growth of Pinus densiflora forest according to spatio-temporal is possible. The result of the study can be useful in establishing the forest management practices, considering the adaptation of climate change.

The Impacts of Chinese Seaborne Trade Volume on The World Economy (중국 품목별 수출입이 세계 경제에 미치는 영향 실증분석)

  • Ahn, Young-Gyun;Lee, Min-Kyu
    • Korea Trade Review
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    • v.42 no.6
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    • pp.111-129
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    • 2017
  • According to the World Bank statistics, China's contribution to global economic growth during the year of 2013-2016 was estimated at 31.6 percent. This figure is even larger than 29.0 percent, the contribution by summing each contribution of the United States, EU and Japan. The Chinese commodity trade accounts for up to 11.5 percent of world trade volume. Thus, we can consider that the Chinese economy has a strong influence on the global economy. The primary purpose of this study is to analyze the contribution level of Chinese seaborne trade volume on world economy. First, this study conducted a time-lag analysis using Moran test, so we can find that China's level of contribution to global economic growth varies from time to time. The contribution of the first phase (1999-2007) was nearly three times higher than the contributions from the second phase (2008-2016), suggesting that the overall contraction of the global trade volume starting from the subprime mortgage crisis in 2008 has continued until recently and recovery has not even occurred. Second, using the econometrics model, this study conducted an regression analysis of the impact of Chinese imports and exports in chemicals, grain, steel, crude oil, and container on global economic growth. Fixed effects model with time series data has been applied to examine the effect of Chinese seaborne trade volume on global economic growth. According to the empirical analysis of this study, China's exports of steel products, exports of container, imports of containers, imports of crude oil and imports of grain have significant contributions to global economic growth. Estimates of China's exports of steel products, exports of container, imports of containers, imports of crude oil and imports of grain are 1.023, 1.020, 1.019, 1.007 and 1.006, respectively. For example, the estimated value 1.023 of China's exports of steel products means that the growth rate can be 1.023 times higher than the current world GDP growth rate if Chinese seaborne trade volume of exports of steel products increased by one unit (one million tons). This study concludes that the expansion of China's imports and exports should be realized first to increase the global GDP growth rate. The expansion of Chinese trade can lead to a simultaneous stimulus of production and consumption in China, which can even lead to global economic growth ultimately. Thus, depending on how much China's trade will be broaden in the future, the width of global economic growth can be determined.

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