• 제목/요약/키워드: growth simulation

검색결과 1,085건 처리시간 0.03초

Simulation of Dynamic Behavior of Glucose- and Tryptophan-Grown Escherichia coli Using Constraint-Based Metabolic Models with a Hierarchical Regulatory Network

  • Lee Sung-Gun;Kim Yu-Jin;Han Sang-Il;Oh You-Kwan;Park Sung-Hoon;Kim Young-Han;Hwang Kyu-Suk
    • Journal of Microbiology and Biotechnology
    • /
    • 제16권6호
    • /
    • pp.993-998
    • /
    • 2006
  • We earlier suggested a hierarchical regulatory network using defined modeling symbols and weights in order to improve the flux balance analysis (FBA) with regulatory events that were represented by if-then rules and Boolean logic. In the present study, the simulation results of the models, which were developed and improved from the previou model by incorporating a hierarchical regulatory network into the FBA, were compared with the experimental outcome of an aerobic batch growth of E. coli on glucose and tryptophan. From the experimental result, a diauxic growth curve was observed, reflecting growth resumption, when tryptophan was used as an alternativee after the supply of glucose was exhausted. The model parameters, the initial concentration of substrates (0.92 mM glucose and 1 mM tryptophan), cell density (0.0086 g biomass/1), the maximal uptake rates of substrates (5.4 mmol glucose/g DCW h and 1.32 mmol tryptophan/g DCW h), and lag time (0.32 h) were derived from the experimental data for more accurate prediction. The simulation results agreed with the experimental outcome of the temporal profiles of cell density and glucose, and tryptophan concentrations.

시뮬레이션 및 너겟 성장 곡선을 이용한 자동차 차체용 3겹 강판의 저항점 용접성 분석 (Analysis of Weladbility on Resistance Spot Weld for 3 Steel Sheets of Automotive Car Body Using Simulation Method and Nugget Growth Curve)

  • 박영환
    • 한국산학기술학회논문지
    • /
    • 제11권9호
    • /
    • pp.3155-3160
    • /
    • 2010
  • 최근 자동차 산업은 고효율 자동차의 개발에 박차를 가하고 있으며 이에 따라 차체 경량화 및 내식성 방지를 위한 고강도강 및 도금강의 사용이 증가하고 있다. 이에 따라 본 연구에서는 자동차 차체에 쓰이는 3종의 다른 강판에 대하여, 겹침 순서에 따른 용접 특성을 시뮬레이션 기법을 이용하여 분석하였다. 자동차 차체에 많이 사용되는 EDDQ 급의 도금강판 0.7t와 인장강도 440 MPa급의 440R 1.2t, 그리고 AHSS (Advanced High Strength Steel)인 DP 590 0.2t 판재에 대하여 겹치기 순서에 따른 용접 특성을 시뮬레이션 하였고, 너겟 성장 곡선 및 전류에 따른 너겟의 크기로 그 용접성을 분석하였다. 또한 용접 시 발생되는 각 접촉부의 접촉저항을 이용하여 겹침순서에 따른 너겟의 크기를 분석하였으며, 이를 통해 최적의 겹치기 순서를 제안할 수 있었다.

Possibility of Climate Change and Simulation of Soil Moisture Content on Mt. Hallasan National Park, Chejudo Island, Korea

  • Kim, Eun-Shik;Kim, Young-Sun
    • The Korean Journal of Ecology
    • /
    • 제23권2호
    • /
    • pp.117-123
    • /
    • 2000
  • Changing patterns and the possibility of climate change in the area of Cheiudo island, the southernmost Island in Korea, were analyzed using daily temperature and Precipitation data observed at the Cheiu Regional Meteorological Office from May 1923 to December 1998. A hydrologic simulation model "BROOK" was used to simulate and analyze the dynamics of daily soil moisture content and soil moisture deficit by applying the daily weather data. During the period, significantly increasing pattern was observed in temperature data of both annual and monthly basis, while no significantly changing pattern was observed in precipitation data. During the last 76 years. mean annual temperature was observed to have risen about 1.4$^{\circ}C$, which may show the Possibility of the initiation of climate change on the island whose validity should be tested in future studies after long-term studies on temperature. Based on the simulation, due to increased temperature, significant increase was predicted in evapotranspiration. while no significant decrease was detected in simulated soil moisture content during the period. Changing pattern of annual soil moisture content was markedly different from those of precipitation. In some dominant trees, negative effects of the drought of the late season for the previous year were shown to be statistically significant to radial growth of the tree for the current year. As annual variation of radial growth of trees is mainly affected by the soil moisture content. the information on the dynamics of soil moisture deficit possibly provides us with useful information for the interpretation of tree growth decline on the mountain. mountain.

  • PDF

PWSCC Growth Assessment Model Considering Stress Triaxiality Factor for Primary Alloy 600 Components

  • Kim, Jong-Sung;Kim, Ji-Soo;Jeon, Jun-Young;Kim, Yun-Jae
    • Nuclear Engineering and Technology
    • /
    • 제48권4호
    • /
    • pp.1036-1046
    • /
    • 2016
  • We propose a primary water stress corrosion cracking (PWSCC) initiation model of Alloy 600 that considers the stress triaxiality factor to apply to finite element analysis. We investigated the correlation between stress triaxiality effects and PWSCC growth behavior in cold-worked Alloy 600 stream generator tubes, and identified an additional stress triaxiality factor that can be added to Garud's PWSCC initiation model. By applying the proposed PWSCC initiation model considering the stress triaxiality factor, PWSCC growth simulations based on the macroscopic phenomenological damage mechanics approach were carried out on the PWSCC growth tests of various cold-worked Alloy 600 steam generator tubes and compact tension specimens. As a result, PWSCC growth behavior results from the finite element prediction are in good agreement with the experimental results.

Analysis of Hygrothermal Performance of Wood Frame Walls according to Position of Insulation and Climate Conditions

  • Kang, Yujin;Chang, Seong Jin;Kim, Sumin
    • Journal of the Korean Wood Science and Technology
    • /
    • 제44권2호
    • /
    • pp.264-273
    • /
    • 2016
  • The insulation of a building envelope influences the hygrothermal performance as well as the thermal performance of the building. While most of Korean wood frame houses have an interior insulation system, the exterior insulation system with high thermal performance has recently been applied. While it can be effective in energy savings for better insulation performance, without consideration of the moisture, condensation and mould growth can occur. Therefore, in this study, hygrothermal behaviour, water content, and mould growth were analyzed using hygrothermal simulation of an exterior wall of a wood frame house with which the interior insulation and exterior insulation systems were applied. The wall layer included Wall A (Interior insulation) and Wall B (Exterior insulation). The U-values were identified as 0.173 and $0.157W/m^2K$, respectively. The total water content and OSB absolute water content of Wall A were confirmed to be higher than those of Wall B, but the absolute water content did not exceed the reference value of 20%. The moisture content of the two walls was determined to be stable in the selected areas. However, mould growth risk analysis confirmed that both Wall A and Wall B were at risk of mould growth. It was confirmed that as the indoor setting temperature decreased, the mould index and growth rate in the same area increased. Therefore, the mould growth risk was affected more by indoor and outdoor climate conditions than by the position of the insulation. Consequently, the thermal performance of Wall B was superior to that of Wall A but the hygrothermal performances were confirmed to be similar.

Large-Scale Integrated Network System Simulation with DEVS-Suite

  • Zengin, Ahmet
    • KSII Transactions on Internet and Information Systems (TIIS)
    • /
    • 제4권4호
    • /
    • pp.452-474
    • /
    • 2010
  • Formidable growth of Internet technologies has revealed challenging issues about its scale and performance evaluation. Modeling and simulation play a central role in the evaluation of the behavior and performance of the large-scale network systems. Large numbers of nodes affect simulation performance, simulation execution time and scalability in a weighty manner. Most of the existing simulators have numerous problems such as size, lack of system theoretic approach and complexity of modeled network. In this work, a scalable discrete-event modeling approach is described for studying networks' scalability and performance traits. Key fundamental attributes of Internet and its protocols are incorporated into a set of simulation models developed using the Discrete Event System Specification (DEVS) approach. Large-scale network models are simulated and evaluated to show the benefits of the developed network models and approaches.

시뮬레이션 시험에 의한 황산화세균의 생장 특성 및 생화학적 부식 저항성 평가 (Evaluation of Properties of Sulfur-Oxidizing Bacteria Growth and Resistance to Biochemical Corrosion by Simulation Test)

  • 김규용;이의배;길배수;이승훈
    • 콘크리트학회논문집
    • /
    • 제20권4호
    • /
    • pp.495-502
    • /
    • 2008
  • 본 연구에서는 황산화세균의 생장과 이에 따른 콘크리트의 생화학적 부식의 단계적인 개연성을 실증적으로 분석하기 위해 고안된 생화학적 부식 시뮬레이션 시험 및 장치를 구축하였으며, 황산화세균인 Thiobacillus novellus의 생장 활성화를 위해 여러 기본조건을 설정하였다. 또한 세균의 이식 방법과 황화수소농도 조건에 따라 크게 2종류의 시험이 진행되었으며, 이에 따른 Thiobacillus novellus의 생장특성과 항균금속의 첨가에 따른 항균성능을 검증할 수 있었다. 우선 황화수소 120 ppm의 조건하에서 시험체를 세균배양액에 침지시켜 Thiobacillus novellus을 간접적으로 이식한 시뮬레이션 시험의 경우, 사슬형태의 대단위 군집을 형성하는 Thiobacillus novellus의 급속한 생장과 높은 황원소의 검출을 관찰할 수 있었으나 장기적으로 Thiobacillus novellus의 생장을 유도하기는 곤란하였다. 황화수소 50 ppm의 조건하에서 황산화세균인 Thiobacillus novellus를 직접 이식한 시뮬레이션 시험의 경우, Thiobacillus novellus의 비교적 장기적인 개별생장이 관찰되었으며, 항균금속을 첨가한 시험체에서 세포막과 내부 조직이 파괴된 Thiobacillus novellus의 개체가 관찰되어 항균금속 성분에 의한 Thiobacillus novellus의 생장억제 성능을 실증적으로 검증하는 것이 가능하였다.