• Journal of Microbiology and Biotechnology
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• v.23 no.11
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• pp.1529-1535
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• 2013

Tuberculosis is a worldwide epidemic disease caused by Mycobacterium tuberculosis, with an estimated one-third of the human population currently affected. Treatment of this disease with aminoglycoside antibiotics has become less effective owing to antibiotic resistance. Recent determination of the crystal structure of the M. tuberculosis Rv3168 protein suggests a structure similar to that of Enterococcus faecalis APH(3')-IIIa, and that this protein may be an aminoglycoside phosphotransferase. To determine whether Rv3168 confers antibiotic resistance against kanamycin, we performed dose-response antibiotic resistance experiments using kanamycin. Expression of the Rv3168 protein in Escherichia coli conferred antibiotic resistance against $100{\mu}M$ kanamycin, a concentration that effected cell growth arrest in the parental E. coli strain and an E. coli strain expressing the $Rv3168^{D249A}$ mutant, in which the catalytic Asp249 residue was mutated to alanine. Furthermore, we detected phosphotransferase activity of Rv3168 against kanamycin as a substrate. Moreover, docking simulation of kanamycin into the Rv3168 structure suggests that kanamycin fits well into the substrate binding pocket of the protein, and that the phosphorylation-hydroxyl-group of kanamycin was located at a position similar to that in E. faecalis APH(3')-IIIa. On the basis of these results, we suggest that the Rv3168 mediates kanamycin resistance in M. tuberculosis, likely through phosphotransferase targeting of kanamycin.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.31 no.1C
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• pp.14-19
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• 2006

The high encoding complexity of LDPC codes can be solved by designing structured parity-check matrix. If the parity-check matrix of LDPC codes is composed of same type of blocks, decoder implementation can be simple, this structure allow structured decoding and required memory for storing the parity-check matrix can be reduced largely. In this parer, we propose a construction algorithm for short block length structured LDPC codes based on girth condition, PEG algorithm and variable node connectivity. The code designed by this algorithm shows similar performance to other codes without structured constraint in low SNR and better performance in high SNR than those by simulation

• Proceedings of the KIEE Conference
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• 2005.07a
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• pp.712-714
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• 2005

With rapid growth of industry, underground power delivery systems are growing so rapidly and its capacity also growing. So if there are any accident in underground power cable, its inference is too great to count. So power system operators should find Its fault location as soon as possible and replace it But it is difficult to find its fault location for underground power cable. We are developing fault location system for underground power cable which can detect its fault location exactly. This system usually monitor underground power cable on-line But if there are an accident, it record Its transient signal and we can calculate fault location by analyzing it. To develop fault location system for power cable, we needed fault simulation system and we installed it physically and tested at various point. in this thesis, we describe on signal processing technology to detect fault location on power cable and on the result of tested fault location performance.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.14 no.6
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• pp.183-188
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• 2014

With the rapid growth of the mobile computing and sensor technologies, various application techniques related to USN converged with other related technologies are actively disseminated recently. Most of these applications are aimed at the proper control and system monitoring using context information gathered through various sensors. But it is not easy to control and monitor the system precisely and flexibly since data generated by sensors are huge and variety. In this paper, we design and implement the fuzzy-logic based central control system in USN to provide the flexibility and preciseness with sensed data. The performance of the proposed system is evaluated by a simulation study in terms of consumed electric power on the test bed of USN based streetlight control system.

• Journal of The Korean Association of Information Education
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• v.15 no.4
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• pp.533-542
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• 2011

In this paper, we have selected traveling algorithms of Line-Tracer as the focused learning elements with the PBL-based programming instruction method. Line-Tracer traveling algorithm programming has been simulated using the Scratch EPL. Development of robot web courseware such as Line-Tracer can create an effective educational environment and also provide solutions for lack of environmental conditions, such as time or spatial factor restrictions and excessive expense issues; these are major obstacles to developing robot programming education. Finally, we analyzed the effects on growth of student's logical thinking and problem solving abilities by demonstrating the Scratch application courseware to the field of elementary education.

• KSBB Journal
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• v.9 no.1
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• pp.72-84
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• 1994

A model to explain the observed kinetics in a whole process of Cheddar-cheese ripening has been developed. It includes growth and lysis of cells in the cheese matrix, cell-wall bound protelnases and intracellular dipeptidases that are released into cheese upon cell lysis, and the production of dipeptides and amino acids from casein in cheese. Model simulations have been conducted to figure out the crucial factors in the process of the cheese ripening. The influential factors have been found to be the cell numbers and the dipeptidase activity at the beginning of the cheese ripening, and the cell-lysis rate of cheese starters. The simulation results have also suggested the use of a mixed culture as well as the experimental screening for a more suitable organism as a cheese starter hence, the model shows how to accelerate the cheese ripening.

• Bulletin of Food Technology
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• v.9 no.2
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• pp.111-127
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• 1996

Potassium Sorbate의 향균능력측정결과 효모(Saccharomyces cerevisiae)의 성장에 대하여 uncompetitive 기작으로 작용하였다. 열처리 실험의 결과 Potassium Sorbate는 가열온도에 대하여 Arrhenius, 또한 가열시간에 대하여 1차반응식관계로 향균능력을 잃었으며 따라서 보존제로 Potassium Sorbate를 식품에 첨가후 포장, 가열살균하는 일반 식품가공공정상에서 가열살균공정이 첨가 보존제의 잔류향균능력을 잃게 하는 것으로 나타났다. 플라스틱 film과 치즈안에서 Potassium Sorbate의 확산계수 및 확산에 의한 물질전달 현상을 수학적모델과 컴퓨터 simulation 그리고 실험에 의해 구하였다. 저밀도폴리에틸렌(LDPE)이 범용플라스틱중에서 가장 작은 확산계수를 가져 빠른 물질전달이 요구되는 film층 또는 약물저장층으로 적합한것으로 나타났다. 그외 고밀도 폴리에틸렌(HDPE)과 폴리프로필렌(PP), 폴리에스터(PET)는 느린 물질전달이 요구되는층 또는 복합다층 film에서 물질전달에 단방향성을 주는 고차단층으로 적합한것으로 나타났다. Potassium Sorbate분말과 LDPE resin분말을 섞은후 단일스크루 익스트루더로 항균성 포장 film을 제조한 결과 LDPE film의 tensile strength과 elongation, elastic modulus는 Potassium Sorbate를 3% 이상 포함할때까지 변화하지 않았다. 그러나 film의 투명도는 급격히 낮아졌다. 향균성LDPE film은 효모가 접종된 한천배지상에서 항균물질인 Potassium Sorbate를 배지위로 서서히 방출시켜 효모의 성장속도(growth rate)를 저하시키고 초기성장지체기(lag period)를 연장시킨다. 따라서 식품포장재로 적용시에 미생물의 오염을 막고 식품저장기간을 연장할것이라 여겨진다.

• Journal of Korea Foundry Society
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• v.32 no.5
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• pp.219-224
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• 2012

The effects of Mg and Si contents on the microstructure and mechanical properties in Al-Mg alloy (ALDC6) were investigated. The results showed that phase fraction and size of $Mg_2Si$ and $Al_{15}(Fe,Mn)_3Si_2$ phase in the microstructure of Al-Mg alloy were increased as the Mg and Si contents were raised from 2.5 to 3.5 wt%. With Si content of 1.5 wt%, freezing range of the alloy was significantly reduced and solidification became more complex during the final stage of solidification. While there was no significant influence of Mg contents on mechanical properties, Si contents up to 1.5 wt%, strongly affected the mechanical properties. Especially elongation was reduced by about a half with more than 1.0 wt%Si in the alloy. The bending and impact strength were decreased with increased amount of Si in the alloy, as well. The lowered mechanical properties are because of the growth of particle shaped coarse $Mg_2Si$ phase and precipitation of the needle like $\beta$-AlFeSi in the microstructure at the last region to solidify due to presence of excess amount of Si in the alloy.

• International Journal of Precision Engineering and Manufacturing
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• v.6 no.3
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• pp.29-36
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• 2005

With the rapid growth of the Internet, the Internet-based robot has been realized by connecting off-line robot to the Internet. However, because the Internet is often irregular and unreliable, the varying time delay in data transmission is a significant problem for the construction of the Internet-based robot system. Thus, this paper is concerned with the development of an Internet-based robot system, which is insensitive to the Internet time delay. For this purpose, the PPS (Position Prediction Simulator) is suggested and implemented on the system. The PPS consists of two parts : the robot position prediction part and the projective virtual scene part. In the robot position prediction part, the robot position is predicted for more accurate operation of the mobile robot, based on the time at which the user's command reaches the robot system. The projective virtual scene part shows the 3D visual information of a remote site, which is obtained through image processing and position prediction. For the verification of this proposed PPS, the robot was moved to follow the planned path under the various network traffic conditions. The simulation and experimental results showed that the path error of the robot motion could be reduced using the developed PPS.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.12 no.10
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• pp.4703-4723
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• 2018

In recent years, dense small cell network has been deployed to address the challenge that has resulted from the unprecendented growth of mobile data traffic and users. It has proven to be a cost efficeient solution to offload traffic from macro-cells. Software defined heterogeneous wireless network can decouple the control plane from the data plane. The control signal goes through the macro-cell while the data traffic can be offloaded by small cells. In this paper, we propose a framework for cell virtualization and user association in order to satisfy versatile requirements of multiple tenants. In the proposed framework, we propose an interference graph partioning based virtual-cell association and customized physical-cell association for multi-homed users in a software defined small cell network. The proposed user association scheme includes 3 steps: initialization, virtual-cell association and physical-cell association. Simulation results show that the proposed virtual-cell association outperforms the other schemes. For physical-cell association, the results on resource utilization and user fairness are examined for mobile users and infrastructure providers.