• Journal of the Korean Society of Tobacco Science
• /
• v.11 no.1
• /
• pp.27-39
• /
• 1989

This study was conducted to determine the time and methods of predicting tobacco yield. by analysis of climatic factors in the period of tobacco season during 8 years from 1979 to 1986 at the Daegu district, south eastern part of Korean peninsular. The results obtained are summarised as follows: 1. Climatic factors of each month which have influence on tobacco yield were the amount of rainfall in May and sunshine hours in July. Among climatic factors at tobacco growth stages, the precipitation yield. But these meteorological factors had different effect on variety. 2. Between tobacco yields and climatic factors by even values of each month, tobacco yield was estimated by equations, flue cured tobacco :Y=190.6-5.230X1+ 0.474$\times$2 + 0.142X3(Xl : Minimum temperature of April, X2: Precipitation during May, X3:Sunshine duration on July), air cured tobacco : Y= 195.3-0.447Xl + 0.363$\times$2 + 0.l12$\times$3(Xl :Maximum temperature of May, X2:Precipitation during May. X3: Sunshine duration on July). While between tobacco yield and climatic factors at different growth stage, predicting equation of yield could be derived, flue cured tobacco : Y=205.8+0.510Xl +0.289$\times$2 + 0.305$\times$3 (Xl :Average temperature during the early growth stage, X2 :Precipitation during the early and maximum growth stage, X3 : Sunshine hours during the leaf and tips maturing stage), air cured tobacco Y=194.T-0.498Xl 10.615$\times$2+0.121$\times$3(Xl ;Maximum temperature during the transplanting time, X2 : Precipitation during the maximum growth stage, X3 : Sunshine hours during the leaf and tips maturing stage).

• Journal of Korean Society of Forest Science
• /
• v.83 no.3
• /
• pp.380-390
• /
• 1994

This study was conducted to investigate the effects of the topographical factors (16 items), physico-chemical properties of soil (13 items) and meteorological factors(9 items) on the height growth of Pinus thunbergii stands along the coastal area in Korea. According to the coefficients by partial correlation analysis in total area, it was found that tree height growth was considerably affected by local topography, soil hardness, soil B-horizental depth, effective soil depth, soil moisture, parent rock, soil texture, and etc.. And the soil factors were available $P_2O_5$, total nitrogen, base saturation, exchangeable $Ca^{{+}+}$, and etc.. In partial correlation analysis, annual relative humidity, annual precipitation, index of aridity, and etc. were found to be the most important factors influencing on tree height growth of Pinus thunbergii stands. In conlusion, the topographical, soil and meteorological factors have multiplex influence on the tree height growth in the Pinus thunbergii stands. They promise to provide the basis of improving not only the selection of suitable sites and the management of soil fertilizer but also the estimation of growth and yield. Hence these results would be used successfully for the design in the scientific forest working plan.

• The Journal of Dong Guk Oriental Medicine
• /
• v.9
• /
• pp.1-23
• /
• 2000

Osteoporosis is a common disorder characterized by reduced bone mineral density, deterioration of the microarchitecture of bone tissue and increased risk of fracture. The aim of treatment of osteoporosis is to maintain and, ideally, to restore bone strength safely. In recent years the role of polypeptide growth factors in bone metabolism has begun to appear. It has been proposed that alterations in the expression or production of growth factor can modulate the proliferation and activity of bone forming cells. Thus, the role of structurally diverse peptides for the management and diagnosis of osteoporosis has attracted the attention of many investigators. This paper reviews numerous findings concerning the use of polypeptides, hormones, and growth factors, for the management of osteoporosis. Many of the compounds mentioned here are experimental prototypes of new therapeutic classes. Though it is unlikely that some of the compounds may ever be used clinically, development of safe and efficacious agents in each class will define the future course of therapy for osteoporosis.

• Korean Management Science Review
• /
• v.34 no.1
• /
• pp.15-25
• /
• 2017

We evaluated industry growth and employment effects of every possible pairs of 22 manufacturing sectors and 16 regions (i.e, 352 region-sectors). We used annual data of manufacturing sectors from 2008 to 2014 for the evaluation. The evaluation comprises of two steps; We first find several region-sectors that outperform others with respect to the effects of industry growth and employment, which are measured by location quotient analysis, shift share method, employment to GDP ratio and employment elasticity. In addition, cross-efficiency analysis follows to classify region-sector pairs into two sub-categories : efficient region-sectors that deserve to hold the current level of investments and inefficient region-sectors where we should consider efficiency improvements. To examine the efficiency, R&D investment, employment size, and capital investment were used as input factors and production volume, added value, changes in employment size, changes in annual salary per capita were used as output factors. For region-sector pairs that have outstanding growth and employment effects but are inefficient, we employed a CCR DEA model and analyzed how much to adjust the values of input and output factors to improve the efficiency scores. The analysis results showed that inefficiency is mainly due to several factors such as R&D investment, changes in employment size and changes in annual salary per capita.

• Applied Microscopy
• /
• v.43 no.1
• /
• pp.27-33
• /
• 2013

Inflammatory cells express the inflammatory cytokines and growth factors induced by lipopolysaccharide (LPS). Odontoblasts are located at the pulp-dentin interface and extend their cell processes far into the dentin where they are the first cells to encounter microorganisms or their products. Therefore, this study examined the expression of some growth factors related to the signal pathway, such as growth factor receptor binding protein 2 (Grb2)-Ras in odontoblast-like dental pulp cells, after a treatment with LPS. After 60 minutes, the mRNA and protein expression levels of Grb2 and Ras were higher in the LPS-treated cells than in the control cells. The level of vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF) mRNA expression was increased significantly to a level similar to that of Grb2 and Ras at 60 minutes. The platelet-derived growth factor-AA (PDGF-AA) mRNA level was expressed strongly in the odontoblast like dental pulp cells without an association with LPS stimulation. Scanning electron microscopy revealed many extensions of the cytoplasmic processes and the number of processes increased gradually at 30, 60 and 90 minutes after LPS stimulation. From these results VEGF and bFGF expression might be induced through the Grb2-Ras signal transduction pathway in LPS treated odontoblasts.

• Proceedings of the Korean Society of Machine Tool Engineers Conference
• /
• 2003.04a
• /
• pp.398-404
• /
• 2003

Most previous researches for the hybrid composite materials such as FRMLs(Al/AFRP, Al/GFRP) have evaluated the fatigue delamination behavior using the traditional fracture mechanism. However, most previous researches have not generally been firmed yet. Because delamination growth behavior in hybrid composite should be consider delamination growth rate, $dA_D$/da using the delamination shape factors, fs instead of traditional fracture mechanic parameters. The major purpose of this study was to evaluate the relationship between delamination shape factor, fs and delamination growth rate, $dA_D$ . And a propose parameter on the delamination aspect ratio, b/a. The details of the study are as follow : 1) Relationship between crack length, a and delamination width,b. 2) Relationship between delamination aspect ration, b/a and delamination area rate,($(A_D)_{N}(A_D)_{ALL}$. 3) Variation of delamination growth rate, $dA_D/da$ was attendant on delamination shape factors, $fs_1$, $fs_2$, $fs_3$. The test results indicated the delamination growth rate depends on delamination shape factors.

• Knowledge Management Research
• /
• v.20 no.2
• /
• pp.197-216
• /
• 2019

The Korean government has been focusing on supporting technology startups to solve social and economic problems such as low growth, declining economic growth rate, rising youth unemployment rate and lack of new growth engine. Although the failure rate of young technology startups is very high, relevant researches are still scant. On the basis of previous researches, this study has identified four growth factors of technology startups: characteristics of entrepreneurs, technical superiority and originality of business items, focused marketing strategy, and follow-up government support projects. Five young technology startup cases were selected and analyzed in the cosmetics industry which were supported by the Six-month Challenge Platform project of Chungbuk Creation Economic Innovation Center. The main findings of the case study were as follows: First, product development through inhouse R&D rather than external contracted R&D was beneficial to acquiring follow-up government support projects and external investment. Second, choosing a small niche market and concentrating marketing efforts on the target market had a positive effect on firm performance. And, third, relevance of entrepreneurs' college major and technological originality of business items were confirmed to influence firm performance positively in the early stage. The results are expected to help young technology startups survive successfully and establish a foothold for growth in their early stage.

• Journal of Distribution Science
• /
• v.21 no.1
• /
• pp.23-31
• /
• 2023

Purpose: this study is aimed at assessing the contribution of education and innovation to the economic growth of Kazakhstan, the correlation between them is checked based on two levels on a national scale and a regional scale. Based on the literature review, it was revealed that in the vastness of the scientific community, there are many views concerning the influence of educational and innovative factors on economic growth. Research design, data and methodology: the research methodology is divided into two levels, at the first level, a correlation analysis is carried out between key factors and the economic growth of the country (GDP), at the second level, the same factors are analyzed, but the impact on the economic growth of the region (GRP) is estimated. Statistical data on educational and innovation potential is taken from the Bureau of National Statistics for the period 2003-2021. Results: in this study, it was revealed that the economic development of regions could be influenced by such indicators that cannot affect the entire state in aggregate and vice versa. In addition, the correlation analysis results showed that investments in innovations affect economic growth at the country and the regional level. Conclusions: based on the results of the assessment of educational and innovative potential, policy recommendations and further research in this area were proposed.

• Journal of Korean Society of Forest Science
• /
• v.107 no.1
• /
• pp.35-42
• /
• 2018

This study was carried out to investigate site and soil factors affecting growth of root collar diameter (RCD) and height (HT) of Larix kaempferi trees planted in harvested Larix kaempferi plantations. We were found effect factors of growth of RCD and HT using 15 of site and soil factors. And then we made the growth estimated equations of RCD and HT of 6-years-old L. kaempferi tree by the derived affecting factors. The growth of RCD was affected in order of available phosphorus (+), effective soil depth (+), organic matter (-), sand separate in soil (-), pH (-), and elevation (-), and the coefficient of determination ($R^2$) of the growth estimated equation of RCD was 0.51. The growth of HT was affected in order of effective soil depth (+), elevation (-) slope (-), and available phosphorus (+) and the $R^2$ of the growth estimated equation of HT was 0.46. The growth of RCD and HT were commonly affected by effective soil depth, available phosphorus, and elevation. Therefore, planting site of L. kaempferi should be considered the mainly effect factors in order to keep better early growth based on the current study.

• Biomolecules & Therapeutics
• /
• v.31 no.1
• /
• pp.89-96
• /
• 2023

Uric acid produced by guanine deaminase (GDA) is involved in photoaging and hyperpigmentation. Reactive oxygen species (ROS) generated by uric acid plays a role in photoaging. However, the mechanism by which uric acid stimulates melanogenesis in GDA-overexpressing keratinocytes is unclear. Keratinocyte-derived paracrine factors have been identified as important mechanisms of ultraviolet-induced melanogenesis. Therefore, the role of paracrine melanogenic growth factors in GDA-induced hypermelanosis mediated by uric acid was examined. The relationships between ROS and these growth factors were examined. Primary cultured normal keratinocytes overexpressed with wild type or mutant GDA and those treated with xanthine or uric acid in the presence or absence of allopurinol, H₂O₂, or N-acetylcysteine (NAC) were used in this study. Intracellular and extracellular bFGF and SCF levels were increased in keratinocytes by wild type, but not by loss-of-function mutants of GDA overexpression. Culture supernatants from GDA-overexpressing keratinocytes stimulated melanogenesis, which was restored by anti-bFGF and anti-SCF antibodies. Allopurinol treatment reduced the expression levels of bFGF and SCF in both GDA-overexpressing and normal keratinocytes exposed to exogenous xanthine; the exogenous uric acid increased their expression levels. H₂O₂-stimulated tyrosinase expression and melanogenesis were restored by NAC pretreatment. However, H₂O₂ or NAC did not upregulate or downregulate bFGF or SCF, respectively. Overall, uric acid could be involved in melanogenesis induced by GDA overexpression in keratinocytes via bFGF and SCF upregulation not via ROS generation.