• Title/Summary/Keyword: growth factors

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Growth Factors and Their Function in Colostrum: A Review (초유에 함유된 성장인자와 기능: 총설)

  • Renchinkhand, Gereltuya;Son, Ji Yoon;Nam, Myoung Soo
    • Journal of Dairy Science and Biotechnology
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    • v.34 no.1
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    • pp.1-7
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    • 2016
  • Colostrum, a nutrient-rich fluid produced by female mammals after giving birth, is the specific initial diet of mammalian neonates. Colostrum is important for the nutrition, growth, and development of newborn infants and contributes to the immunologic defense of neonates. It contains immunoglobulins, antimicrobial peptides, such as lactoferrin and lactoperoxidase, and other bioactive molecules, including growth factors, such as IGF (insulin-like growth factor), EGF (epithermal growth factor), $TGF-{\beta}$ (transforming growth factor), and FGF (fibroblast growth factor). Bovine colostrum is a rich source of growth factors, which play a central role in wound healing. The biological activities of colostrum emphasize the relevance of the synergistic activity of growth factors to stimulate keratinocyte proliferation and migration, which are essential for tissue repair. Colostrum increases the expression of early differentiation markers, such as keratin 1 and 10 and involucrin, and late differentiation markers, including loricrin and filaggrin. Additionally, colostrum increases granulation tissue volume in the dermis, suggesting that it has a beneficial effect on wound healing. The therapeutic use of colostrum or individual peptides present in colostrum has a positive and curative influence on various gastrointestinal diseases.

Soil Environment's Impact on the Growth of Pinus thunbergii by Season in Urban Forests (도시림의 계절별 토양환경이 곰솔의 생육에 미치는 영향)

  • Kim, Seok-Kyu
    • Journal of Environmental Impact Assessment
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    • v.20 no.4
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    • pp.455-464
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    • 2011
  • The purpose of this study is to clarify correlations between soil environments and the growth of trees in forests and thereon analyze effects of seasonal changes in such environments on such growth. To determine seasonal factors of soil affecting the Tree Vitality of Pinus thunbergii, first of all, the study designated the Tree Vitality as a dependent variable and soil hardness, moisture, pH, K, Na, Mg and Ca as independent variables. Then the study performed Pearson's coefficient analysis. To clarify what soil factors influence the seasonal growth of Pinus thunbergii multiple regression analysis is carried out, and findings are as follow; the growth of Pinus thunbergii was basically influenced by pH, followed by soil hardness in spring, K, followed by moisture in summer, and by soil hardness in winter. However, no soil factors affected the vitality at the significance level of 5% for t.

An Analysis of Sasa Borealis' Growth Properties and Positional Environmental Factors in Jirisan National Park (조릿대의 생장특성 및 입지환경요인 분석)

  • Park, Seok-Gon
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.16 no.2
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    • pp.53-61
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    • 2013
  • The present study elucidated the growth properties of Sasa borealis communities distributed in the lower layer of deciduous broadleaf forests in temperate zones and analyzed the correlation between the growth properties of S. borealis and positional environmental factors. The higher the culm height of S. borealis was, the higher the values of the leaf number, leaf area, and foliage layer thickness became. This might be because as the culm height of S. borealis increased, the acquisition of light sources became easier so that the biomass of leaves increased simultaneously for smooth anabolism. S. borealis seem to change their growth mode for smooth acquisition of light resources. The culm density of S. borealis and the leaf number, leaf area and foliage layer thickness of S. borealis did not show any clear correlation. The values of the culm height, leaf number, leaf area, and foliage layer thickness of S. borealis as the above altitude of the location of S. borealis increased. It seems like that growth conditions such as temperatures and winds are deteriorated as the above altitude of the location of S. borealis increased so that S. borealis becomes smaller. No clear correlations were shown between the physiochemical properties of soil and S. borealis' growth properties. It seems like that the growth of S. borealis complexly intertwined with diverse environmental factors and that due to the physiological integration of S. borealis, certain physiochemical properties do not unilaterally affect S. borealis' growth properties.

An Exploratory Study on the Success Factors of Research-based Spin-off Venture Across Stages of Growth: Pertaining to Theoretical and Case Study (연구기반 스핀오프 벤처기업의 성장단계별 성공요인에 관한 탐색적 연구: 이론 및 사례 연구를 중심으로)

  • Jung, Gang-Ok
    • Journal of Korea Technology Innovation Society
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    • v.9 no.4
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    • pp.654-687
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    • 2006
  • Research-based spin-off venture, generally formed to commercialize technology originating from public research institution, could contribute to economic wealth creation and regional development. Although there are some interests in research-based spin-off venture and its success factors across stages of growth, little empirical research was done on research-based spin-off venture's success factors in Korea. The purpose of this research is to investigate research-based spin-off venture's success factors across stages of growth. The methodology used is theoretical and case study. Based on theoretical study, it is found that there are four stages of growth in research-based spin-off ventures such as generating business ideas, finalizing new venture projects, launching spin-off firm, and strengthening the creation of economic value. Then, in order to verify them, a case was analyzed focused on success factors across stages of growth. Additionally, implications and limitations of the result of this study are discussed.

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Role of Growth Differentiation Factor 9 and Bone Morphogenetic Protein 15 in Ovarian Function and Their Importance in Mammalian Female Fertility - A Review

  • Castro, Fernanda Cavallari de;Cruz, Maria Helena Coelho;Leal, Claudia Lima Verde
    • Asian-Australasian Journal of Animal Sciences
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    • v.29 no.8
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    • pp.1065-1074
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    • 2016
  • Growth factors play an important role during early ovarian development and folliculogenesis, since they regulate the migration of germ cells to the gonadal ridge. They also act on follicle recruitment, proliferation/atresia of granulosa cells and theca, steroidogenesis, oocyte maturation, ovulation and luteinization. Among the growth factors, the growth differentiation factor 9 (GDF9) and the bone morphogenetic protein 15 (BMP15), belong to the transforming growth factor beta (TGF-${\beta}$) superfamily, have been implicated as essential for follicular development. The GDF9 and BMP15 participate in the evolution of the primordial follicle to primary follicle and play an important role in the later stages of follicular development and maturation, increasing the steroidogenic acute regulatory protein expression, plasminogen activator and luteinizing hormone receptor (LHR). These factors are also involved in the interconnections between the oocyte and surrounding cumulus cells, where they regulate absorption of amino acids, glycolysis and biosynthesis of cholesterol cumulus cells. Even though the mode of action has not been fully established, in vitro observations indicate that the factors GDF9 and BMP15 stimulate the growth of ovarian follicles and proliferation of cumulus cells through the induction of mitosis in cells and granulosa and theca expression of genes linked to follicular maturation. Thus, seeking greater understanding of the action of these growth factors on the development of oocytes, the role of GDF9 and BMP15 in ovarian function is summarized in this brief review.

A Study on Correlation between Height Growth, Obesity and Bone maturity in Childhood (소아기에 있어 키성장과 비만도, 골성숙도와의 상관성 연구)

  • CHoi, Sang Rak;Kim, Yun Young;Jang, Eun Jin;Koo, Jin Suk
    • The Journal of Korean Medicine
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    • v.40 no.1
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    • pp.24-33
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    • 2019
  • Objectives: The purpose of this study is to analyze the causes of short stature through a clinical review of factors related to childhood height growth. So we can find the way to meet the needs of the heightism which is widely spread among modern people. Methods: Among 160 patients who came to Andong B oriental clinic for the purpose of growth therapy, 112 children whose height was smaller than other normal children were analyzed. When the children first came to the clinic, we checked their height and weight. The parents' height was recorded through a questionnaire. The relationship between obesity index and height growth was examined through growth plate test and Inbody test. We want to identify the genetic factors related to parental factors based on the data of the parent height. Results: For short stature children, weight was often normal or low. When we examined the relationship between parental genetic factors and child growth, we found that they were more influenced by father's height rather than mother's. We investigated the correlation between skeletal maturity and the five viscera. There was no apparent correlation between skeletal maturity and the five viscera but we found that there was some degree of relevance. Conclusions: For short stature children, the weight was often normal or low and parental genetic factors were more influenced by father than by mother. In the case of bone maturity it did not show a direct correlation between the five viscera.

Internal Company Factors as Determining Variables for Improving Bank Lending

  • PRAWITASARI, Dian;KADARNINGSIH, Ana;MACHMUDDAH, Zaky;UD-DIN, Maaz
    • The Journal of Asian Finance, Economics and Business
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    • v.7 no.8
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    • pp.205-212
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    • 2020
  • This study seeks to examine the main factors, external and internal to the bank, that enhance bank lending. Bank lending is one of the connecting bridges in sustaining society. Internal factors consist of ROA, DPK, and CAR. External factors are economic growth and interest rate of Bank Indonesia. The population of this research consists of traditional commercial banks listed on the IDX over the 2014-2017 period. Samples were chosen by purposive sampling method. This study uses secondary data with 56 samples; data analysis uses multiple linear regression. The findings of the study show that internal factors have a greater impact on increasing bank lending than external factors. The main variable among internal factors that influences increase in bank lending is ROA. DPK is the internal factor with the smallest impact on increasing bank lending. The implication of the study is that determining the bank lending should take more account of CAR, DPK, ROA, BI interest rates, and economic growth in making decisions about the amount of lending. These variables can only have a slight effect on increasing lending, though. Besides, internal factors such as NPL, LDR or non-economic factors also need to be considered in channeling bank credit.

A Study on Succeeding Together-Busan New Port & BJFEZ (부산항 신항과 부산진해경제자유구역의 연계 발전 방안)

  • Song, Gye-Eui
    • Journal of Korea Port Economic Association
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    • v.28 no.1
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    • pp.123-142
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    • 2012
  • The purpose of this paper is to suggest a plan on succeeding together-Busan New Port & BJFEZ(that is, port hinterland development). This study deals with the terms of three connection growth factors which are a firm's subjective factors, a industrial environment factors, and a governmental policy factors. According to analysis results of the factors, a firm's subjective factors(4.11 score) are scored the most ones of connection growth factors of Busan New Port & BJFEZ, to be compared with a governmental policy factors(4.01 score). with a industrial environment factors(3.92 score). Therefore, first of all, Busan New Port & BJFEZ have to promote connection growth through as follows, a firm's subjective factors : (1) to procure competitiveness through establishment of connection growth model, (2) to promote concentrated marketing strategy & market response ability, (3) speedy meeting to customer's needs, (4) to procure reliability of Busan New Port & BJFEZ. And, the next, Busan New Port & BJFEZ have to promote connection growth through considering a governmental policy factors, a industrial environment factors.

A Study on Success Factors of Marine Special Economic Zone (해양경제특구의 성공 요인)

  • Song, Gye-Eui
    • Journal of Korea Port Economic Association
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    • v.31 no.1
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    • pp.51-68
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    • 2015
  • Recently, it has been emphasized that 'marine special economic zone' need to be designated and developed. Therefore, the purpose of this paper is to analyse on successful growth factors of 'marine special economic zone'. This study deals with the terms of three connection success factors which are a firm's subjective factors, a industrial environment factors, and a governmental policy factors. According to analysis results of the three successful growth factors, a firm's subjective factors(4.11 score) are scored at the most ones of the three successful growth factors, to be compared with a industrial environment factors(3.89 score). with a government policy factors(3.72 score). Therefore, first of all, it is important to enhance competitiveness of 'marine special economic zone' through as follows, a firm's subjective factors : (1) to procure concentrated market strategy and real market capacity, (2) to promote customer service, (3) to procure speedy satisfaction of customer needs and confidence, (4) to enhance competitiveness through standing in a trio of connection growth model. And, the next, we have to enhance competitiveness of 'marine special economic zone' through considering a industrial environment factors, that is, sustainable growth of marine industry, clustering of marine industry, expansion of infrastructure, etc., and a government policy factors, that is, leading law improvement and policy of leading 'marine special economic zone' designation and development, etc.,

A Study on Success Factors for Entrepreneurs in IT Ventures (IT 창업 기업의 창업 성공 요인에 대한 연구)

  • Shin, Yu-Sub;Choi, Myeong-Gil
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.11 no.7
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    • pp.2371-2385
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    • 2010
  • What are the success factors of IT venture entrepreneur that through initial phase and enter to the growth phase ? Both the duration of jobless growth and the economic recession are worsening employment market. Entrepreneurship is be proposed to a method for creating jobs and reducing the economic gap. Research on Entrepreneurship and the support of government policy has already been operated for a long time ago. Research on growth and duration of the entrepreneur in initial phase, compared with growth phase are insignificant in quantity or quality. Therefore, this study researches essential factors about growth and duration of the entrepreneur in the initial phase through cases related them. entrepreneur of this subject are classified the hardware development group and the software development group associated with manufacturing characteristic funded existence. There is a research on evaluation factors about selection and result evaluation of selecting Entrepreneur. And this can be investigated by studying to Entrepreneur's growth and duration in initial phase. There are affecting factors about growth and duration of first step. And they are divided by internal, external, synthetic, and characteristic factors of growth phase. The result of this study is be used to develop pre-established educational program, consulting guidelines and establish support policy.