• Journal of Plant Biology
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• 제6권4호
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• pp.1-4
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• 1963

Using conidia of Neurospora, changes in respiratory activities and the sensitivity to the ultraviolet light of the cells at different growing stages were measured by manometric methods, and the correlation between them was observed. Efficiency in the utilization of various carbon sources, such as, glucose, sucrose, maltose, starch and sodium acetate, in growth and exogenous respiration of N. crassa was also determined. Growth rate of N. crassa was decreased considerably in the medium containing sodium acetate than in the glucose medium and was almost zero in the lactose medium, whereas the utilization of sucrose, maltose and starch was ve교 high, as that of glucose. Respiratory activities of the cells veried considerably depending upon their different growing stages. Actively growing hyphae exhibited the greatest activity in exogenous glucose respiration, followed by germinating and activated conidia in decreasing order. There was no proportional relationship between the dose of ultraviolet light irradiated and its effect on the respiratory activity of the cells, though the more the dose of ultraviolet light, the more the injury. The sensitivity of the cells to ultraviolet light varied with the different respiratory activities of the cells linked to the developmental stages. In general, the more actively growing cells having high respiratory activities exhibited the more serious injury.

• 지역연구
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• 제10권1호
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• pp.39-52
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• 1994

This paper primarily aims to analyze the growth rate differentials of the economic activities in chung-Nam area. The research has been undertaken to find out the potentials of the economic activities and economic bases in the area. To analyze the economic potentials of the industries, the study employed the economic Growth Rate Differential Analysis by Henderson which is revised form of Shift-Share Analysis Methods. The research employed the employment data according to the standardized two-digit-classification-system during the period of 10 years from 1981 through 1991. The Growth Rate Differential Analysis calculates Total Growth Differentials which are dicomposed into two parts: Weight Part and Rate Part. Total Growth Differential can be calculated as the difference between national growth rate and regional growth rate by industry. The foundings are as follows: First, the economic bases of Chung-Nam area were found to be very weak, largely depending on primary industries such as agriculture and fisheries. Second, there was a great decline in urban industries in Tae Joeon, Cheon An and other cities over period of 1971-1981. It is strongly recommended that the planned items and products of each industrial complex must be reorgnized in a fashion to match those with high competitive power found in this research.

• The Korean Journal of Ecology
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• 제27권2호
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• pp.107-114
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• 2004

Tomato (Lycopersicon esculentum) seedlings exposed to various concentrations of $CdC1_2$ (0∼100 $\mu$M) in the nutrient solution for up to 9 days were analyzed with the seedling growth, $H_2O_2$ production, glutathione levels and activity changes of enzymes related to $H_2O_2$ removal. The growth of seedlings was inhibited with over 50 $\mu$M Cd, whereas the levels of $H_2O_2$ and glutathione were enhanced with Cd exposure level and time. Meanwhile, Cd exposure increased the activities of catalase (CAT) and glutathione reductase (GR) but decreased the activities of dehydroascorbate acid reductase (DHAR) and ascorbate peroxidase (APX) in both leaves and roots. These results suggest that the altered activities of antioxidant enzymes particularly involved in the $H_2O_2$ removal and the subsequent $H_2O$$_2$ accumulation could induce the Cd-induced phytotoxicity.

• Asian-Australasian Journal of Animal Sciences
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• 제20권10호
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• pp.1600-1605
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• 2007

This study was undertaken to investigate the effects of oxidative stress on growth performance, nutrient digestibilities and activities of antioxidant enzymes of weanling pigs. In the experiment, 24 male $Landrance{\times}Yorkshire $weanling pigs were allotted to three groups of 8 animals each. Pigs were fed individually. According to a single factorial arrangement, pigs received diets with 5% of either fresh (group 1 and group 3) or oxidized fish oil (peroxide value was 786.50 meq $O_2/kg$ before inclusion in the diet, group 2). At the beginning of the experiment, pigs in group 3 received an intraperitoneal injection of diquat at 12 mg/kg of body weight. The trial lasted for 26 d. A metabolism test was carried out during the last 4 days of the second week. The results showed that feeding diets containing oxidized fish oil or injection with diquat depressed the growth performance and nutrient digestibilities of weanling pigs, decreased activities of antioxidant enzymes and increased concentration of malondialdehyde in plasma and liver. Intraperitoneal injection of diquat would induce more serious oxidative stress than oral intake of oxidized fish oil in the diet. In conclusion, administration of oxidized fish oil or diquat could induce oxidative stress in weanling pigs, and oxidative stress could depress growth performance and impact anti-oxidative ability of young pigs.

• 한국식품영양과학회지
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• 제41권2호
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• pp.261-269
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• 2012

본 연구에서 18종의 한약재추출물을 제조하여 병원성세균에 대한 한약재의 항균활성을 측정하였다. 오배자, 오미자 및 소목 메탄올 추출물은 대부분 균주에 대해 5 mg/mL 수준에서 항균활성을 나타냈으나 15여 종의 한약재추출물들은 30 mg/mL 수준에서 항균활성을 나타냈다. 오배자의 S. epidermidis와 Bor. bronchiseptica에 대한 최소저해농도는 0.6 mg/mL로 나타났다. 우수한 항균활성이 확인된 오배자, 소목, 오미자, 황금을 대상으로 극성이 다른 5가지 용매로 순차 분획하여 항균활성을 검토한 결과 대부분의 균주에서 EtOAc층이 다른 분획층에 비해 성장억제효과가 높게 나타났다. 항균력이 우수한 한약재추출물의 미생물 증식억제 효과를 조사하기 위해 증식배지에 0, 100, 300 및 500 ppm의 메탄올 추출물을 첨가하였다. 한약재 추출물을 첨가하지 않은 대조구에서는 12시간 이후 급격한 균의 성장을 나타내고 있으나 오배자와 소목추출물의 첨가 농도가 높을수록 그람 양성균인 S. aureus, S. epidermidis 및 L. monocytogenes는 뚜렷한 억제효과를 나타냈다. 오배자추출물은 그람음성균인 Sal. Pullorum과 Sal. Choleraesuis의 성장을 저해하였고 Bor. bronchiseptica, E. coli serotype $O_8$은 오배자와 소목추출물은 낮은 농도에서 성장이 다소 저해되었음을 보여주었고, 추출물의 농도가 높을수록 균의 성장이 강하게 억제되었다.

• The Korean Journal of Ecology
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• 제26권3호
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• pp.115-121
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• 2003

Leaves of two-week old seedlings of tomato (Lycopersicon esculentum) were treated with various concentrations (0∼100 M) of $CdCl_2$ for up to 9 days and subsequent growth of seedlings, symptoms of oxidative stress and isozyme activities of antioxidant enzymes including superoxide dismutase (SOD), catalase (CAT), ascorbate peroxidase (APX) and peroxidase (POX) were investigated. Compared with the non-treated control, Cd exposure decreased biomass but increased Cd accumulation, hydrogen peroxide production and lipid peroxidation as malondialdehyde (MDA) formation in leaves and roots. Further studies on the developmental changes of isozyme activities showed that Fe-SOD, Cu/Zn-SOD and one of three APX isozymes decreased and CAT and one of four POX isozymes increased in leaves, whereas Fe-SOD, one of three POX isozymes and two of four APX isozymes decreased and CAT increased in roots, showing different expression of isozymes in leaves and roots with Cd exposure level and time. Based on our results, we suggest that the reduction of seedling growth by Cd exposure is the oxidative stress resulting from the over production of $H_2O_2$ and the insufficient activities of antioxidant enzymes particularly involved in the scavenging of $H_2O_2$. Further, the decreased activities of SOD and APX isozymes of chloroplast origin, the increased activities of CAT and POX and high $H_2O_2$ contents with Cd exposure might indicate that Cd-induced oxidative stress starts outside chloroplast.

• 기술혁신연구
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• 제16권1호
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• pp.215-237
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• 2008

KIPRIS patent database was analyzed for identifying the technological status of Daedeok Innopolis Biocluster. It was found that the pattern of activities among various technological areas in Daedeok Biocluster is similar to that of an advanced country rather than those of other cities in Korea. The technological growth in Daedeok Innopolis Biocluster is in the progressive stage, which may be due to the innovative activities rather than the rise in the number of new firms or institutes. The concentration of technology in Daedeok Innopolis Biocluster is a favorable condition for the innovation activities. The trend for the technological concentration was remarkably consistent with the growth curve that a population increases according to the logistic equation. The logistic growth may be represented by the result of competition due to the limited resource allocation and then innovation cluster is corresponding to the ecosystem composed by biological individuals. There is strong competition in Daedeok Innopolis Biocluster in around 2009, so the government might make a policy to encourage the technological diversity for healthy knowledge ecosystem.

• 한국산학기술학회논문지
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• 제13권11호
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• pp.5130-5139
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• 2012

글로벌화 시대의 역동적 경영환경 측면에서나 국가경제 전략측면에서 볼 때 창업활동은 경제의 유연성, 산업구조와 노동시장의 유연화, 국가경제의 균형적인 발전에 그게 기여하고 있다. 이에 창업활동이 성장의도를 매개로 기업성과에 미치는 영향을 살펴본 연구목적은, 현재 중국에서 기업경영하고 있는 기업가들 402명을 대상으로 어떤 영향이 있었는지를 확인하고 발견하기 위한 것이다. 본 연구에서 창업활동은 창업가의 주관적 활률(실현가능성)에 대한 믿음으로, 성장의도는 최고경영자인 기업가의 성장에 대한 의지로 정의되었으며, 기업성과는 기업의 비재무적 성과로 측정되었다. 다중회귀분석 방법을 활용해서 연구가설을 검정한 연구결과에 따르면 제시된 가설 모두가 채택되었다. 즉 중국기업가의 창업활동이 성장의도 및 기업성과에 모두 유의한 정(+)영향을 미치는 것으로 나타났다. 그리고 성장의도가 기업성과에 유의한 정(+)의 영향을 미치는 것으로 나타났다. 특히 성장의도가 매개효과를 가졌는지 검정하는 결과에서는 성장의도가 보완적 부분매개역할을 하는 것으로 나타났다. 본 연구는 중소기업 창업가의 창업프로세스과정에서의 관련된 첫 탐색적인 연구로서 공헌점이 적지 않다. 가령 창업전체 프로세스에서 살펴볼 수 있는 중요 변수들 간의 인과관련 모형을 토대로 한 탐색적 이론적 검토 및 실증적 검증 모두를 살폈다는 공헌은 인정할 만하기 때문이다.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2007년도 춘계학술대회A
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• pp.485-489
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• 2007

Knowledge-based economy is the economy or economic structure based on production, accumulation and utilization of knowledge. With the emergence of knowledge-based economy, the importance to the corporate competitiveness of IP and IP-related activities has increased. This paper discuss the issues related to the mode of IP-related activities, including the comparison of SMEs and large firms. Especially, I focus on the role and impact of IP-related activities on innovation and growth of firm in machinery industry. The result of this study can help to set up strategy for supporting firm's technology innovation.

• Journal of Microbiology and Biotechnology
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• 제8권3호
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• pp.229-236
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• 1998

6-Substituted derivatives of 1-［(2-hydroxyethoxy)methyl］-6-(phenylthio)thymine (HEPT) were synthesized by introducing alkyl groups with the aid of chlorotrimethylsilane, and then purified ranging 40 to 81 % of yield. Because of their peculiar structures, we presumed that HEPT derivatives would contain extra biological activities other than their already known anti-human immunodeficiency viral (HIV -1) activities. In this study, we investigated the possible effects of the HEPT derivatives on bacterial growth and found their selective antibiotic activities against gram-positive strains. We could not observe the corresponding activity from a disc-zone test, but confirmed the activity by liquid cultivation. Since the growth rate of cells was easily recovered, the antibiotic function was suggested to be bacteriostatic. We also suggested that the intracellular fate of HEPT derivatives would be fast. A HEPT derivative f-3 was shown to synergize unidirectionally toward chloramphenicol (Chr). With 0.1 mM f-3, the Chr-directed growth-inhibitory curve appeared 4 hours earlier than found without the additive. Interestingly, from the data of SDS-polyacrylamide gel electrophoresis (PAGE), we found that a membrane-bound protein having a molecular weight of 70-kDa was overexpressed by f-3 in S. aureus.