• Journal of Korean Physical Therapy Science
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• v.6 no.2
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• pp.1019-1040
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• 1999

The purpose of this study is to clarify the repercussions of swimming exercise therapy that has an effect on lipid in blood and liver enzyme of the 3D-Rat dosage high fat diet. The object of this study consisted of two groups. One was the swimming exercise SD-Rat group, the other was the non-exercise SD-Rat group. Sample size was seven Rats repectively. Exercise period was ten week. Exercise group swimmed twenty minutes per a day and 5 times per a week. And then collecting blood from these two group's SD-Rats, making M Health center a request for a blood test on TC, TG, GOT, GPT, we come to a conclusion like below. The weight of the swimming exercise group has decreased 5.93% in comparison with non-exercise group. and has a significant difference(p<0.05). The liver weight of the swimming exercise group has decreased 7.83% in comparison with non-exercise group, and has not a significant difference. The TC of the swimming exercise group has decreased 39.22% in comparison with non-exercise group, and has a significant difference(p<0.05). The TG of the swimming exercise group has decreased 62.88% in comparison with non-exercise group, and has a significant difference(p<0.05). The GOT of the swimming exercise group has decreased 3.22% in comparison with non-exercise group, and has not a significant difference. The GPT of the swimming exercise group has decreased 16.14% in comparison with non-exercise group, and has a significant difference(p<0.05). In regard to above results, the regular swimming exercise therapy with dosage of high fat diet has an important role in healing and preventing a fattyliver, a hyperlipidemia, and an arteriosclerosis, intervening the lipid in blood.

• Journal of Sasang Constitutional Medicine
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• v.23 no.3
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• pp.374-390
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• 2011

1. Objectives: The purpose of this study is to investigate the effect of Suhwagije-tang(SGT) distillate on the immune activity of spleen cells of aged SD rats. 2. Methods: We used 10, 50, 72 weeks old SD rats in this study. Spleen cells from SD rats were stimulated with ConA and treated with 1% Vitamin C(Vit.C) or Suhwagijetang distillate(SGT). After 24 hours, the concentrations of IL-2, IL-4, IL-10, IFN-${\gamma}$ in the cell culture supernatant were measured by ELISA. 3. Results and Conclusions 1) At all concentration of SGT distillate, survival rates of liver cells were higher than the control group. In addition, 50% SGT distillate group's cell survival rates were significantly higher than other groups. 2) In 10 weeks SD rats(SGT group), the concentration of IL-2 significantly decreased in comparison with ConA group, Vit.C group. In 52 weeks SD rats(SGT group), the concentration of IL-2 significantly decreased in comparison with ConA group. 3) In 10, 52 weeks SD rats(SGT group), the concentration of IL-4 significantly decreased in comparison with ConA group. 4) In 10 weeks SD rats(SGT group), the concentration of IL-10 significantly decreased in comparison with ConA group. And in 72 weeks SD rats(SGT group), the concentration of IL-10 significantly increased in comparison with Vit.C group. 5) In 52, 72 weeks SD rats(SGT group), the concentration of IFN-${\gamma}$ significantly decreased in comparison with 10 weeks SD rats(SGT group). These results suggest that Suhwagije-tang(SGT) distillate has the effect of increasing the immune activity of spleen cells of aged SD rats.

• Journal of Korean Physical Therapy Science
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• v.28 no.3
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• pp.30-41
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• 2021

Background: The purpose of this study was to investigate the effects of WBC on the pressure pain threshold, CK and LDH after exercise-induced muscle injury. Design: A Randomized Controlled Trial. Methods: In this study, these subjects were assigned into three groups, a control group (n=10), experiment group I (n=10) and experiment group II (n=10). The subjects in experimental group I were intervened by WBC (-130℃, 3 minutes) before induced EIMD, experimental group II were intervened by WBC (-130℃, 3 minutes) after induced EIMD and control group weren't by any intervened after induced EIMD. Results: First, In the comparison of the PPT, there were significant variations with the lapse the time in three groups (p<.001) and there was a significant interaction of time and group (p<.001). In the among group comparison, the PPT of experimental group II was significantly larger than those of other groups (p<.01). Second, In the comparison of the CK, there were significant variations with the lapse the time in three groups (p<.001) and there was a significant interaction of time and group (p<.001). In the among group comparison, the CK of experimental group II was significantly smaller than those of other groups (p<.001). Third, In the comparison of the LDH, there were significant variations with the lapse the time in three groups (p<.01) and there was a significant interaction of time and group (p<.001). In the among group comparison, the LDH of experimental group II was significantly smaller than those of other groups (p<.001). Conclusion: The above results revealed that the WBC intervention after an exercise had a positive effect of muscle function after EIMD.

• Journal of Physiology & Pathology in Korean Medicine
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• v.18 no.5
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• pp.1476-1484
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• 2004

Aging is characterized by an age-dependent reduction in bone density. Pronounced bone loss by postmenopausal estrogen deficiency induces a bad effect on dynamic balance of bone metabolism. When the bone density is reduced to the level below the fracture threshold, the risk for fracture is greatly increased. The purpose of this study is to examine what are the effects of the Guisinhwan(GSH : 歸腎丸) on the ovariectomized rat model of postmenopausal osteoporosis. The results of the experiment are as follows: Body weight in control group showed significant increase in comparison with sham, but that in GSH-treated showed no change in comparison with control. The level of serum albumin in control group showed significant decrease in comparison with sham. That in GSH-treated was slightly decreased in comparison with control. The level of serum ALP activity in control group showed significant increase in comparison with sham, but that in GSH-treated was significantly decreased in comparison with control. The level of serum phosphorous, calcium, GOT, GPT, T3 did not significant change among the three groups. The level of serum estrogen in control group showed slightly decreased in comparison with sham, but that in GSH-treated showed no change in comparison with control. The level of serum T4 in control group showed significant increase in comparison with sham, but that in GSH-treated was significantly decreased in comparison with control. Trabecular bone area as well as trabecular thickness in control group showed significant decrease In comparison with sham. Those in GSH-treated showed significant increase in comparison with control. Trabecular number did not significant change among the three groups. Trabecular separation only in GSH-treated showed significant decrease in comparison with control. Osteoclast number in control group showed significant increase in comparison with sham. That in GSH-treated showed significant decrease in comparison with control. Oseoblast surface in control group showed significant increase in comparison with sham, but that in GSH-treated showed no change in comparison with control. According to the above these results, GSH has shown to be capable of preventing and curing osteoporosis caused by old-aged and postmenopause.

• Journal of Acupuncture Research
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• v.24 no.3
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• pp.145-161
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• 2007

Objectives : The purpose of this study is to investigate the effect of electroacupuncture at Joksanmi($ST_{36}$) on Rat's aging by experimental methods. Methods : The author performed several experimental procedures to observe the effects of the EC-HAS at the arthritis. First, I measured the cell survival rate of the mice lung fibroblasts. Second, the incidence rate of arthritis and arthritis index of CIA were analyzed. Third, the levels of IL-6, $INF-{\gamma}$ , $INF-{\alpha}$ , $IL-1{\beta}$, IgG, IgM and anti-collagen II were measured in serum and the level of $INF-{\gamma}$, $INF-{\gamma}$/IL-4 ratio in the CIA mouse spleen cell culture. Fourth, histological analysis of the mice joint was performed. Fifth, the expression ratio of $CD3e^+$ cells to $CD19^+$ cells, $CD4^+$ cells to $CD8^+$ cells, $CD11a^+CD19^+$ cells, $CD4^+CD25^+$ cells, $CD3^+CD69^+$ cells, and $CD11b^+Gr-1^+$ cells were checked. Results: 1. The hematocrit was meaningfully (p<0.01, p<0.05) decreased in $ST_{36}$ group in comparison with the control and sham group. 2. The glucose, ALP were meaningfully (p<0.05, p<0.05) decreased in $ST_{36}$ group in comparison with the control group. 3. In the activation of hepatic antioxidase, the catalase was meaningfully (p<0.01) increased in $ST_{36}$ group in comparison with the control group. 4. In the liver, the NO formation was meaningfully (p<0.001) decreased in $ST_{36}$ group in comparison with the nomal, control and sham group. 5. In the activation of splenetic antioxidase, the GSH was meaningfully (p<0.01) increased in $ST_{36}$ group in comparison with the sham group, and the catalase was meaningfully (p<0.001) increased in $ST_{36}$ group in comparison with the control group. 6. In the spleen, the MDA formation was meaningfully (p<0.01, p<0.05) decreased in $ST_{36}$ group in comparison with the control and sham group. 7. In the spleen cell culture, the levels of IL-6 was meaningfully (p<0.05) decreased in comparison with the sham group, $INF-{\gamma}$( was meaningfully (p<0.05) increased in comparison with the control group. Conclusions: According to the results, it is considered that electroacupuncture at Joksamni($ST_{36}$) is effective in increasing the activities of antioxidative enzyme and inhibiting lipid peroxides, and has an immunomodulatory reaction. In conclusion, it han an significant anti-aging effect and need more experimental study.

• The Korea Journal of Herbology
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• v.26 no.3
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• pp.31-36
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• 2011

Objectives : This study was performed to investigate the effect of water extracts from Phyllostachys Folium(PF) on hyperlipiderma and liver damage induced by alcohol. Methods : Except for the normal group, we fed rat on 25% alcohol for 55 days. And extract was administrated for the same period. We measured the serum component in rat's blood, body weight and weight of liver. Results : At first, we observed effects of PF on hyperlipidemia induced by alcohol. PF group didn't show significant change of total cholesterol in comparison with those of the control group. PF group showed significant increase of HDL(High-Density lipoprotein) cholesterol in comparison with those of the control group. PF group showed significant decrease of triglyceride in comparison with those of the control group. PF group showed significant increase of body weight in comparison with those of the control group at 4weeks and 8weeks. At second, I observed effects of PF group on liver damage induced by alcohol. PF group showed significant decrease of GOT, GPT, ALP and LDH in comparison with those of the control group. PF group showed significant increase of liver weight in comparison with those of the control group. Conclusions : Reviewing these experimental results, it appears that water extracts from Phyllostachys Folium(PF) have pharmaceutical efficacy on hyperlipidemia and liver damage induced by alcohol. Therefore further additional study should be conducted to elucidate in depth the pharmaceutical efficacy of these.

• Journal of Korean Physical Therapy Science
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• v.27 no.3
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• pp.56-66
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• 2020

Background: The purpose of this study was to investigate the effects of pulsed-ultrasound intervention and continued-ultrasound on the PPT (pressure pain threshold), CK (creatine kinase) and LDH (lactate dehydrogenase) recovery of before EIMD (exercise-induced muscle damage). Design: Randomized Controlled Trial. Methods: Thirty subjects who are student in their 20s at a university participated in this study, these subjects were assigned into three groups, a control group (n=10), experiment group I (n=10), and experiment group II (n=10). The subjects in experimental group were intervened by pulsed-ultrasound and continued-ultrasound, while ones on control group weren't by any intervention after induced EIMD. Results: First, In the comparison of the PPT, there were significant variations with the lapse the time in three groups (p<.001) and there was a significant interaction of time and group (p<.001). In the among group comparison, the PPT of experimental group II was significantly larger than those of other groups (p<.01). Second, In the comparison of the CK, there were significant variations with the lapse the time in three groups (p<.001) and there was a significant interaction of time and group (p<.001). In the among group comparison, the CK of experimental group II was significantly smaller than those of other groups (p<.001). Third, In the comparison of the LDH, there were significant variations with the lapse the time in three groups (p<.001) and there was a significant interaction of time and group (p<.001). In the among group comparison, the LDH of experimental group II was significantly smaller than those of other groups (p<.001). Conclusion: The above results revealed that the continued-ultrasound intervention before an exercise had a positive effect of muscle function after EIMD. Therefore we can consider the continued ultrasound as a considerable intervention method to prevent or reduce an exercise injury.

• Journal of The Korean Society of Integrative Medicine
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• v.9 no.1
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• pp.183-192
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• 2021

Purpose : The purpose of this study was to investigate the impact of postural correction training on pulmonary function on 28 college students suspected of turtle neck syndrome, and the following conclusions were obtained. Methods : Turtle neck syndrome suspicion 28 person were randomly divided into a posture training group (n = 14) and group that does not perform posture training (n = 14). Respiratory function was measured by SPIROVIT SP-1 and respiratory gas analyzer. The posture training group performed balloon blowing and stair climbing after 20 minutes of posture training, and the group without posture training carried out balloon blowing training and stair climbing. Five times a week and for two weeks. Results : 1. The comparison of the FVC before and after experiments caused by balloon blowing showed a higher level of effortful pulmonary function in the control group than in the experimental group. 2. Comparison of PEFs before and after the experiment by balloon blowing showed that the experimental group's peak flow rate was higher than that of the control group. 3. Comparison of the FIVC before and after experiments with balloon blowing showed that the comparison of the FIVC showed a higher level of effortless intake pulmonary function in the control group than in the experimental group. 4. The comparison of the maximum ventilation volume(VE) before and after the experimental gas measurement showed that the maximum ventilation rate of the experimental group was higher than that of the control group. 5. The comparison of pre-test and post-test heart rate(HR) by breath gas measurement showed that the heart rate of the control group was higher than that of the experimental group. Conclusion : the results of this study showed that postural correction training, balloon blowing training, and stair climbing could have a positive impact on improving pulmonary function. However, the two-week experiment conducted five times a week showed an increase in pulmonary function, but it was difficult to see the effect due to the short study period. Therefore, it is hoped that later studies will be conducted more systematically on the effects of breathing exercises on improving pulmonary function after post-postural correction training for patients with pulmonary function problems.

• Journal of Sasang Constitutional Medicine
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• v.7 no.1
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• pp.281-293
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• 1995

In order to investigate the effects of the $So{\breve{u}}m$-In $Sipj{\breve{o}}ndaebot^{\prime}ang$ and the Gukbang $Sipj{\breve{o}}ndaebot^{\prime}ang$ on Yang-insufficient syndrome(陽虛)induced by hydrocortisone acetate and cold condition in experiemental animals(Rats), the author experimented with Body temperature, Body weight, Exercise time, cyclic-AMP and Hair conditions. The results were obtained as follows ; 1. In Changes of body Temperature, the soum-In $Sipj{\breve{o}}ndaebot^{\prime}ang$ group rose with statistical significance in comparison to the controlled group, and the Soum-In $Sipj{\breve{o}}ndaebot^{\prime}ang$ treated group rose with statistical singificance in comparison to the Gukbang $Sipj{\breve{o}}ndaebot^{\prime}ang$ treated group. 2. In changes of Body weight, the Soum-In Sipjondaebot'ang treated group and the Gukbang Sipjondabot'ang treatd group had increased with statistical significance in comparison to the controlled group, and the $So{\breve{u}}m$-In $Sipj{\breve{o}}ndaebot^{\prime}ang$ treated group showed an increasing tendency in comparison to the Gukbang $Sipj{\breve{o}}ndaebot^{\prime}ang$treated group. 3. In changes of Exercise time, the $So{\breve{u}}m$-In $Sipj{\breve{o}}ndaebot^{\prime}ang$ treated group and the Gukbang $Sipj{\breve{o}}ndaebot^{\prime}ang$ treated group had increased with statistical significance in comparison to the controlled group and the $So{\breve{u}}m$ $Sipj{\breve{o}}ndaebot^{\prime}ang$ treated group showed an increasing tendency in comparison to the Gukbang $Sipj{\breve{o}}ndaebot^{\prime}ang$ treated group. 4. In changes of plasma cyclic-AMP concentration, the Gukbang $Sipj{\breve{o}}ndaebot^{\prime}ang$ treated group and the $So{\breve{u}}m$ $Sipj{\breve{o}}ndaebot^{\prime}ang$ treated group showed an increased tendency in comparison to the controlled group. 5. In changes hair condition, the $So{\breve{u}}m$ $Sipj{\breve{o}}ndaebot^{\prime}ang$ terated group and the Gukbang $Sipj{\breve{o}}ndaebot^{\prime}ang$ treated group showed a betterment tendency in comparison to the controlled group. From the above findings, thd $So{\breve{u}}m$ $Sipj{\breve{o}}ndaebot^{\prime}ang$ and the Gukbang $Sipj{\breve{o}}ndaebot^{\prime}ang$ groups also had an effect of Yang-insuffient syndrome, moreover, on Body thmperature, Body weight and Exercise time, both showed a singnificant effect.

• The Korea Journal of Herbology
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• v.23 no.1
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• pp.9-15
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• 2008

Objectives : This study was performed to investigate the effect of water extracts from Lagocephalus wheeled with several herbs(LW) on hyperlipemia and liver damage induced by alcohol. Methods : Except for the normal group, we fed rat on 25% alcohol for 55 days. And each extract was administrated for the same period. We measured the serum component in rat's blood, body weight and weight of liver. Results : At first, we observed effects of LW on hyperlipemia induced by alcohol. LW group didn't show significant increase of total cholesterol in comparison with those of the control group. LW group didn't show significant increase of HDL(High-Density lipoprotein) cholesterol in comparison with those of the control group. LW group showed significant decrease of triglyceride in comparison with those of the control group. LW group showed significant increase of body weight in comparison with those of the control group in 4weeks and 8weeks. LW group showed significant increase of liver weight in comparison with those of the control group. At second, we observed effects of LW on liver damage induced by alcohol. LW group showed significant decrease of ALP, GOT, GPT and LDH in comparison with those of the control group. Conclusions : Reviewing these experimental results, it appears that water extracts from Lagocephalus wheeleri with several herbs have pharmaceutical efficacy on hyperlipidemia and liver damage induced by alcohol. Therefore further additional study should be conducted to elucidate in depth the pharmaceutical efficacy of this.