• Proceedings of the Ginseng society Conference
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• 1984.09a
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• pp.83-88
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• 1984

It is now well established that the rodenticide Vacor (N-3-pyridyl-mehtyl-N'-p-nitropheny-lurea) causes a hyperglycemia in human and rats. It is also reported that there are some components (DPG-3) in ginseng radix which cause hypoglycemic effect on alloxan diabetic mice. In the present study, attempts were made to demonstrate in Vacor-poisoned rats the hypo-glycemic activity of red ginseng component(RGC), which was extracted by Kimura's DPG-3 extraction procedure and found to be effective for lowering a hyperglycemia in alloxan-diabetic rats. Vacor in a dose of $LD_{50}$ (10mg/kg) produced a glucose intolerance with a paradoxical moderate increase in blood immunoreactive insulin and derangement in glucose metabolism of epididymal adipocytes in rats. Although RGC (20mg/kg, i.p.) did not exert any significant influence on a hyperglycemia induced by large lethal doses (25mg/kg) of Vacor ingestion, it improved the LDso Vacor-induced glucose intolerance and caused a further increase in blood insulin levels in Vacor-poisoned rats. The administration of RGC (20mg/kg, i.p.) normalized Vacor-induced depression of glucose metabolism and lipogenesis in the epididymal adipocytes with an improvement of reduced responses to insulin of adipocytes from Vacor-poisoned rats. These results suggest that some red ginsneng components contained in RGC fraction normalize the depressed peripheral glucose unitlization and insulin response and eventually lead to an improvement of abnormal glucose tolerance developed in rats poisoned with small doses of Vacor.

• Journal of Practical Agriculture & Fisheries Research
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• v.25 no.2
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• pp.12-19
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• 2023

This study conducted an experiment with EC 1.0ms/cm ratio and excellent soil conditions for germination in ICT-based ginseng process cultivation. The first growth survey was conducted before transplantation of ginseng 1-year roots grown by seeding ginseng in the process cultivation, conventional cultivation and a second growth comparison survey was conducted after 3 months of growth. In the results, it was confirmed that ginseng grown in the process cultivation grew more than in the field. As a result of comparing the contents of 11 ginsenosides of 1-year and 2-year-old ginsenosides in the process cultivation and conventional cultivation ginseng, it was confirmed that the content of the process cultivation ginseng was higher than that of practice cultivation ginseng. In conclusion, conventional cultivation ginseng grows due to various factors under the natural cultivation environment, but process cultivation can secure the growth stability of ginseng by allowing stable soil and environmental control, so continuous research is needed in the future.